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The map label for this gene is etfA [H]

Identifier: 116327462

GI number: 116327462

Start: 760426

End: 761385

Strand: Reverse

Name: etfA [H]

Synonym: LBL_0679

Alternate gene names: 116327462

Gene position: 761385-760426 (Counterclockwise)

Preceding gene: 116327463

Following gene: 116327461

Centisome position: 21.07

GC content: 48.02

Gene sequence:

>960_bases
GTGAGCAACGTATTAATTGTTGGCGAATTGAAAGATGGAGACTTGAAAAAAATCTCCAGAGAAATCACTTCAGCGGGTAG
AAAAATCGCTGATTCCATCGGAGGAAAAGTTGTAGCTCTTCTCATCGGAAGCGGCGTCGAAAAACACGCTCCCGAACTGG
CTGCGGTTGGTGCAGACACAATTCTTACCGTAAACTCCGGCGACTACAATGCGGAAACATACTCCAACCAAGTTGCGGAA
GTCATCAAAGCACAAAACCCTGCGGTTGTTCTTCTTCCTCATACTTCTCAAGGAAAAGATTATTCTCCTCGTGTTGCGGT
AAAAGTAGGAGCAGGAATCATCGCGGACGTAGTGGGATTCTCCGTTGACGGTGGAAAAGTCGTAGCAAAAAAGCCGATTT
ATTCCGGAAAAGCCTATGCAAACTTTAAAGTAACTAGTCCGATTCAAATCTTTACAGTCCGTCCTAACTCTCAAGAAATC
TCTCAAAAAGCCGGTACCGGTGCCGTAGAAACCGCTTCTCCATCCGCGGGCGACGCGAAAGTAAAAACCGTTTCCACCGA
TCTGAGCGGGGGATCCAAGGTCCAATTGACCGAAGCTTCCATCATCGTTTCCGGCGGACGCGGGATCAAAGGACCTGAGA
ATTGGCCTATCTTACAAGAACTTGCAGATACTCTCGGAGCGGCTCTCGGAGCTTCTCGCGCGGCCGTGGATGCCGGATGG
ATTTCTCACTCTCATCAGGTAGGACAAACAGGAAAAACTGTTTCTCCGAATTGTTACATCGCTTGCGGAATCTCGGGTGC
GATTCAACATTTAGCGGGAATGGGTTCTTCCAAATATATCGTTGCAATCAACAAAGACGGAGACGCTCCGATCTTTAAGG
TTGCGACTTACGGTATCGTAGGCGACCTGTTCGAGGTAGTTCCTGCGGTGACTGCTGAGTTCAAAAAAGTACTTGGATAA

Upstream 100 bases:

>100_bases
TCCAGGTAGAAAACTGGAAGCGGCAGATGCAAACGGTTTTGCATCCCAACTCGTAAAAGCTCTCAGAGAAGAAGCTAAGG
TCATATAAGGAGAACACCCA

Downstream 100 bases:

>100_bases
TCCACCTGCGAAACGACCTATTTCGCGATCTATCGAGTGCCCCTTAGGAAGCGAGATATTGAGTTCAGAGAGCGAAATTG
CGTTAGAGGGAGTTGAGCAT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSNVLIVGELKDGDLKKISREITSAGRKIADSIGGKVVALLIGSGVEKHAPELAAVGADTILTVNSGDYNAETYSNQVAE
VIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGFSVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEI
SQKAGTGAVETASPSAGDAKVKTVSTDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIVGDLFEVVPAVTAEFKKVLG

Sequences:

>Translated_319_residues
MSNVLIVGELKDGDLKKISREITSAGRKIADSIGGKVVALLIGSGVEKHAPELAAVGADTILTVNSGDYNAETYSNQVAE
VIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGFSVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEI
SQKAGTGAVETASPSAGDAKVKTVSTDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIVGDLFEVVPAVTAEFKKVLG
>Mature_318_residues
SNVLIVGELKDGDLKKISREITSAGRKIADSIGGKVVALLIGSGVEKHAPELAAVGADTILTVNSGDYNAETYSNQVAEV
IKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGFSVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEIS
QKAGTGAVETASPSAGDAKVKTVSTDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGWI
SHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIVGDLFEVVPAVTAEFKKVLG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=322, Percent_Identity=39.4409937888199, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI189181759, Length=220, Percent_Identity=47.7272727272727, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1787990, Length=259, Percent_Identity=32.8185328185328, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786226, Length=267, Percent_Identity=32.9588014981273, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87082157, Length=237, Percent_Identity=29.1139240506329, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=320, Percent_Identity=40.9375, Blast_Score=196, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6325261, Length=318, Percent_Identity=34.5911949685535, Blast_Score=155, Evalue=7e-39,
Organism=Drosophila melanogaster, GI17136898, Length=318, Percent_Identity=40.8805031446541, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24652801, Length=318, Percent_Identity=40.8805031446541, Blast_Score=194, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32667; Mature: 32535

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVLIVGELKDGDLKKISREITSAGRKIADSIGGKVVALLIGSGVEKHAPELAAVGADT
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCEECCCCE
ILTVNSGDYNAETYSNQVAEVIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGF
EEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHC
SVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEISQKAGTGAVETASPSAGDAK
CCCCCEEEEECCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHCCCCCEECCCCCCCCCE
VKTVSTDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
EEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIV
HCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHH
GDLFEVVPAVTAEFKKVLG
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNVLIVGELKDGDLKKISREITSAGRKIADSIGGKVVALLIGSGVEKHAPELAAVGADT
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCCCCEECCCCE
ILTVNSGDYNAETYSNQVAEVIKAQNPAVVLLPHTSQGKDYSPRVAVKVGAGIIADVVGF
EEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHC
SVDGGKVVAKKPIYSGKAYANFKVTSPIQIFTVRPNSQEISQKAGTGAVETASPSAGDAK
CCCCCEEEEECCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHCCCCCEECCCCCCCCCE
VKTVSTDLSGGSKVQLTEASIIVSGGRGIKGPENWPILQELADTLGAALGASRAAVDAGW
EEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
ISHSHQVGQTGKTVSPNCYIACGISGAIQHLAGMGSSKYIVAINKDGDAPIFKVATYGIV
HCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHH
GDLFEVVPAVTAEFKKVLG
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]