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The map label for this gene is lolE-1 [H]

Identifier: 116327122

GI number: 116327122

Start: 353423

End: 354796

Strand: Direct

Name: lolE-1 [H]

Synonym: LBL_0298

Alternate gene names: 116327122

Gene position: 353423-354796 (Clockwise)

Preceding gene: 116327118

Following gene: 116327123

Centisome position: 9.78

GC content: 39.59

Gene sequence:

>1374_bases
ATGAAGGTAAATTTGTTCCGAGGTTCTTTGATATTTCTGATAACCTCCCGTTATATTCGAGGATCTCGGGTAGCAGGTCT
TCTCTCGTTGAAATCCAGATTGTCTTTTATTGTTATGACAGTCGGAGTTTCTCTTCTGATTGTCGTCTTATCCATATTCA
ACGGCTTTCAACGGCAAGTAAAAGAATCTCTTTGGCAAGGGGGGCCTCATATCACGGTTGAAAATAAATTCGATTCCGGT
GATATTCAAAATTACGAAAAGATAATTGCTTGGATCCGTAAAAATCCTTATCTCAAGGATAGAATCGTTTCTATCGGCGG
AAGTATTACAAGTCACGGCTTGATTCAAAATGCCAATTCGTTTATTCCCATTATGGTACGTGCGCTTCCCGTCGAAAACA
TTCATGATCTTATCGCGAACCGTCTTACTAATTTTCCTAGAATCGTTCATCACAATAGGGAAGAGATTGAGAAATACAAT
GTCGACAATCAGGTTTTGATTGGGAAAGAAATGGCCGGTCTTTATGATTTTAATCTTGGAGCTAATTTAACCATGGCCGT
TCCTGGCGGTAGGTTTTCCCTTGGGAAAGGCGTGGACGTTTCCATCAAAACATTTCGTACAGTGGGATTTTTTAAAACCG
GTTATTATAATTACGACACACATTACGTTTTTCTCTCGCTTCCGGTCGCACAGAAATTTTTTAATTTGAAGAATTCCGTA
AATCAGATCGCGATCAAAGTGAAATCTTTGGACGATTTGCAGAATTGTAAAAGGGAAATTTTGAAAGAATTTAGGGATCC
CGAATTTGAGAACGAGATCGGTTATTCTGCGTCTTTTAGTGTAAGGACGATTGCAGAGGAACAGGAAAATTTTTTCACGG
CTTTGAAGCTGGAAAAAACAATCATTTCCATCATTGTTTTTTTATTTATCATTCTCGCTGCACTGGGAATGGTCGCGAGC
GTTTATAGTTTAGTGAGAGCGAAAAGAAAATCGATCGGAGTATTAAAAGCTCTCGGGTTGCCTTCGTCCGGGGTCTTACT
GATTTTTACCTTAAATGCAATGGTTGTTGGAGTTCTTGCTTCTCTTGTTGGAGGGGTTTCCGGGATTTTTATAGCAAGTA
ATTTGGAAACGATCGTAAACGGAATTTCCGAGTTAATCAATATGGTCGGATTTTATTTTTATCATTCCGAGTGGACTAAC
GTAGAACTGGTTCCGAAAGACGTTTATTACTTCGATCATATCCCCGTTGATATAGATATTTCATTTATCTTTATGGTGAC
TACTGCCGCTACGATTTTATCCGGAATCGCGGGTTATTTTCCCGCAAGATGGGCCGCCGGTCTTAATCCAGTGGATACGA
TAAGGAACGACTAA

Upstream 100 bases:

>100_bases
GTTTGAGAAACTTTCTTCTTTATTTTTGACATTCTGGTTCGGATTCAGAGAATTGTCAAACTAAGGAAGGATTTCACCTT
CTAATTTTAAGAGTTTTTTG

Downstream 100 bases:

>100_bases
CGTGAGTCTGATTAAAGTAAGAAATCTGGTAAAAAATTACCGTATTCTCGATAAGGAATTTAAGATTCTGGATCACTTGG
ATCTGGACGTGGAAGAAGGT

Product: lipoprotein releasing system, LolE permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKVNLFRGSLIFLITSRYIRGSRVAGLLSLKSRLSFIVMTVGVSLLIVVLSIFNGFQRQVKESLWQGGPHITVENKFDSG
DIQNYEKIIAWIRKNPYLKDRIVSIGGSITSHGLIQNANSFIPIMVRALPVENIHDLIANRLTNFPRIVHHNREEIEKYN
VDNQVLIGKEMAGLYDFNLGANLTMAVPGGRFSLGKGVDVSIKTFRTVGFFKTGYYNYDTHYVFLSLPVAQKFFNLKNSV
NQIAIKVKSLDDLQNCKREILKEFRDPEFENEIGYSASFSVRTIAEEQENFFTALKLEKTIISIIVFLFIILAALGMVAS
VYSLVRAKRKSIGVLKALGLPSSGVLLIFTLNAMVVGVLASLVGGVSGIFIASNLETIVNGISELINMVGFYFYHSEWTN
VELVPKDVYYFDHIPVDIDISFIFMVTTAATILSGIAGYFPARWAAGLNPVDTIRND

Sequences:

>Translated_457_residues
MKVNLFRGSLIFLITSRYIRGSRVAGLLSLKSRLSFIVMTVGVSLLIVVLSIFNGFQRQVKESLWQGGPHITVENKFDSG
DIQNYEKIIAWIRKNPYLKDRIVSIGGSITSHGLIQNANSFIPIMVRALPVENIHDLIANRLTNFPRIVHHNREEIEKYN
VDNQVLIGKEMAGLYDFNLGANLTMAVPGGRFSLGKGVDVSIKTFRTVGFFKTGYYNYDTHYVFLSLPVAQKFFNLKNSV
NQIAIKVKSLDDLQNCKREILKEFRDPEFENEIGYSASFSVRTIAEEQENFFTALKLEKTIISIIVFLFIILAALGMVAS
VYSLVRAKRKSIGVLKALGLPSSGVLLIFTLNAMVVGVLASLVGGVSGIFIASNLETIVNGISELINMVGFYFYHSEWTN
VELVPKDVYYFDHIPVDIDISFIFMVTTAATILSGIAGYFPARWAAGLNPVDTIRND
>Mature_457_residues
MKVNLFRGSLIFLITSRYIRGSRVAGLLSLKSRLSFIVMTVGVSLLIVVLSIFNGFQRQVKESLWQGGPHITVENKFDSG
DIQNYEKIIAWIRKNPYLKDRIVSIGGSITSHGLIQNANSFIPIMVRALPVENIHDLIANRLTNFPRIVHHNREEIEKYN
VDNQVLIGKEMAGLYDFNLGANLTMAVPGGRFSLGKGVDVSIKTFRTVGFFKTGYYNYDTHYVFLSLPVAQKFFNLKNSV
NQIAIKVKSLDDLQNCKREILKEFRDPEFENEIGYSASFSVRTIAEEQENFFTALKLEKTIISIIVFLFIILAALGMVAS
VYSLVRAKRKSIGVLKALGLPSSGVLLIFTLNAMVVGVLASLVGGVSGIFIASNLETIVNGISELINMVGFYFYHSEWTN
VELVPKDVYYFDHIPVDIDISFIFMVTTAATILSGIAGYFPARWAAGLNPVDTIRND

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=442, Percent_Identity=24.8868778280543, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 51023; Mature: 51023

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNLFRGSLIFLITSRYIRGSRVAGLLSLKSRLSFIVMTVGVSLLIVVLSIFNGFQRQV
CEEEEECCHHEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KESLWQGGPHITVENKFDSGDIQNYEKIIAWIRKNPYLKDRIVSIGGSITSHGLIQNANS
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHCCHHHCCCC
FIPIMVRALPVENIHDLIANRLTNFPRIVHHNREEIEKYNVDNQVLIGKEMAGLYDFNLG
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCEEEEEHHHCCEEEECCC
ANLTMAVPGGRFSLGKGVDVSIKTFRTVGFFKTGYYNYDTHYVFLSLPVAQKFFNLKNSV
CCEEEECCCCCEECCCCCCEEHHHHHHHHEEECCEEECCCEEEEEECHHHHHHHHHHCCH
NQIAIKVKSLDDLQNCKREILKEFRDPEFENEIGYSASFSVRTIAEEQENFFTALKLEKT
HHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IISIIVFLFIILAALGMVASVYSLVRAKRKSIGVLKALGLPSSGVLLIFTLNAMVVGVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEHHHHHHHHHHH
SLVGGVSGIFIASNLETIVNGISELINMVGFYFYHSEWTNVELVPKDVYYFDHIPVDIDI
HHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCEEEECCCCEEECH
SFIFMVTTAATILSGIAGYFPARWAAGLNPVDTIRND
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MKVNLFRGSLIFLITSRYIRGSRVAGLLSLKSRLSFIVMTVGVSLLIVVLSIFNGFQRQV
CEEEEECCHHEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KESLWQGGPHITVENKFDSGDIQNYEKIIAWIRKNPYLKDRIVSIGGSITSHGLIQNANS
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHCCHHHCCCC
FIPIMVRALPVENIHDLIANRLTNFPRIVHHNREEIEKYNVDNQVLIGKEMAGLYDFNLG
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCEEEEEHHHCCEEEECCC
ANLTMAVPGGRFSLGKGVDVSIKTFRTVGFFKTGYYNYDTHYVFLSLPVAQKFFNLKNSV
CCEEEECCCCCEECCCCCCEEHHHHHHHHEEECCEEECCCEEEEEECHHHHHHHHHHCCH
NQIAIKVKSLDDLQNCKREILKEFRDPEFENEIGYSASFSVRTIAEEQENFFTALKLEKT
HHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IISIIVFLFIILAALGMVASVYSLVRAKRKSIGVLKALGLPSSGVLLIFTLNAMVVGVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEHHHHHHHHHHH
SLVGGVSGIFIASNLETIVNGISELINMVGFYFYHSEWTNVELVPKDVYYFDHIPVDIDI
HHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEECCEEEECCCCEEECH
SFIFMVTTAATILSGIAGYFPARWAAGLNPVDTIRND
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]