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The map label for this gene is trpG [H]

Identifier: 116327040

GI number: 116327040

Start: 255709

End: 256287

Strand: Direct

Name: trpG [H]

Synonym: LBL_0213

Alternate gene names: 116327040

Gene position: 255709-256287 (Clockwise)

Preceding gene: 116327039

Following gene: 116327041

Centisome position: 7.07

GC content: 43.01

Gene sequence:

>579_bases
ATGCTTCTCCTAATTGATAATTACGATTCTTTCACGTACAATCTTTATCAATATTTTTGTCAGATCGGAAACGAAGTCGA
AGTTTATCGAAACGATAAAATTACGTTAAGCGATATTAACAAACTTGCTCCGAAAGCGATCATTCTTTCTCCTGGTCCGG
GTCGCCCTGAGGATTCCAAAATTTGTTTGGATGTGATCCGCGAACTCGGTGGTAAACTGCCCATTTTCGGAGTTTGTCTT
GGGCATCAAGCGATTGGCCTTGTTCACGGTGGTAAAATCGTATCCGCCCCTTCCATCATGCATGGAAAAATTTCTTTGAT
CGAACACGATGGGAAAGACATCTACAAAGGGATTCCTTCTCCTTTTGTTGCAACTCGCTATCATTCTCTCGTGATTCAAC
CGGAAAGTGTCCCGTCGGAACTCGAAGTAACTTCCAAAACTCCGGATGGGGTGATCATGGGAGTTCGTCACAAAACTAAA
AAGCATCTTTATGGTGTTCAGTTTCATCCGGAATCCATCATGACTAGCGCTGGGCTGGATCTGATCAGAAATTTTTCCTC
GATCGTTCAAGGGTTATGA

Upstream 100 bases:

>100_bases
CGGTTGCCGAGTTGGAACTGGAAGAAACAAAAAACAAAATGGCGGCTCTTTTAAAGGCGGTAGAGTTTGCAAGAAACGGG
CTCAAAGGGGAATGGAAATA

Downstream 100 bases:

>100_bases
AGTTTTTTTTCAGGCTTTTGTCCTATTCCGTACATTATAAATATCGATTCACGTTGGGGATCGTTTTCGCGTTATTGACA
GCCGTTTTAAATGCGGTCTC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLLLIDNYDSFTYNLYQYFCQIGNEVEVYRNDKITLSDINKLAPKAIILSPGPGRPEDSKICLDVIRELGGKLPIFGVCL
GHQAIGLVHGGKIVSAPSIMHGKISLIEHDGKDIYKGIPSPFVATRYHSLVIQPESVPSELEVTSKTPDGVIMGVRHKTK
KHLYGVQFHPESIMTSAGLDLIRNFSSIVQGL

Sequences:

>Translated_192_residues
MLLLIDNYDSFTYNLYQYFCQIGNEVEVYRNDKITLSDINKLAPKAIILSPGPGRPEDSKICLDVIRELGGKLPIFGVCL
GHQAIGLVHGGKIVSAPSIMHGKISLIEHDGKDIYKGIPSPFVATRYHSLVIQPESVPSELEVTSKTPDGVIMGVRHKTK
KHLYGVQFHPESIMTSAGLDLIRNFSSIVQGL
>Mature_192_residues
MLLLIDNYDSFTYNLYQYFCQIGNEVEVYRNDKITLSDINKLAPKAIILSPGPGRPEDSKICLDVIRELGGKLPIFGVCL
GHQAIGLVHGGKIVSAPSIMHGKISLIEHDGKDIYKGIPSPFVATRYHSLVIQPESVPSELEVTSKTPDGVIMGVRHKTK
KHLYGVQFHPESIMTSAGLDLIRNFSSIVQGL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=54.0540540540541, Blast_Score=223, Evalue=9e-60,
Organism=Escherichia coli, GI1787517, Length=192, Percent_Identity=41.6666666666667, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786215, Length=142, Percent_Identity=32.3943661971831, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=51.3089005235602, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=207, Percent_Identity=31.8840579710145, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21142; Mature: 21142

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLIDNYDSFTYNLYQYFCQIGNEVEVYRNDKITLSDINKLAPKAIILSPGPGRPEDSK
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCEEEHHHHHHHCCCEEEECCCCCCCCCCH
ICLDVIRELGGKLPIFGVCLGHQAIGLVHGGKIVSAPSIMHGKISLIEHDGKDIYKGIPS
HHHHHHHHHCCCCCEEEEECCCCEEEEEECCEEEECCCEECCEEEEEEECCCHHHHCCCC
PFVATRYHSLVIQPESVPSELEVTSKTPDGVIMGVRHKTKKHLYGVQFHPESIMTSAGLD
CHHHHHEEEEEECCCCCCCCEEEECCCCCCEEEECCHHHHHHEECEEECHHHHHHHHHHH
LIRNFSSIVQGL
HHHHHHHHHHCC
>Mature Secondary Structure
MLLLIDNYDSFTYNLYQYFCQIGNEVEVYRNDKITLSDINKLAPKAIILSPGPGRPEDSK
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCEEEHHHHHHHCCCEEEECCCCCCCCCCH
ICLDVIRELGGKLPIFGVCLGHQAIGLVHGGKIVSAPSIMHGKISLIEHDGKDIYKGIPS
HHHHHHHHHCCCCCEEEEECCCCEEEEEECCEEEECCCEECCEEEEEEECCCHHHHCCCC
PFVATRYHSLVIQPESVPSELEVTSKTPDGVIMGVRHKTKKHLYGVQFHPESIMTSAGLD
CHHHHHEEEEEECCCCCCCCEEEECCCCCCEEEECCHHHHHHEECEEECHHHHHHHHHHH
LIRNFSSIVQGL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]