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The map label for this gene is tadA [H]

Identifier: 116326904

GI number: 116326904

Start: 72052

End: 72519

Strand: Direct

Name: tadA [H]

Synonym: LBL_0062

Alternate gene names: 116326904

Gene position: 72052-72519 (Clockwise)

Preceding gene: 116326903

Following gene: 116326905

Centisome position: 1.99

GC content: 33.12

Gene sequence:

>468_bases
ATGTACGAATCTTTAAATGATAGGATTCTCTCCGATTTTTTTAAAAGTATGAAAGACTTACTCTTAAAAGAAAGAGAAGA
AGTTCCCAGTTTTACGAGAATCTATCAAAAAGAAGAATTGATTAGCGAAACGTTTAACGAAGTCGAGAAACATTTGGATT
CTTCCTTTCACAGCGAAATTCTTTGCATCCGTGACGCGAAAAAAAAATTAAAAACTCGCTATCTTACAGATTGTACACTC
ATTACCTCCTTGGAACCTTGCCTCATGTGCACAGGTACAATTCTTCTTTCAAGAATTCCGAAAATAATTTATCTTTTACC
TGCACGACAAGGAGAAGGAATTTCGTCTCTCAGTATAGAGATGATTTATTCACGAAATTTTTTTCCCGAACTGATTTGTA
TTCCAGCTGAAATTTCTAAAAATGCATTCAAATCGTTTTTCAAAATCAGAAGAAAGAAATTCAATTGA

Upstream 100 bases:

>100_bases
TGTTACGATGAAAATTAGGATATTTGAAAATGTCCGAAGAACAATATTCATGGGTAGATGGGCAACTTAAAGAGATCGAA
GAATTCAAAATATTAACTGT

Downstream 100 bases:

>100_bases
CATACAACCTCTAGACGGAATTTCTGAAAGCTACAGGAGAAGTGTCAGAGTGGTCTATTGTGCATGCTTGGAAAGCATGT
GTGCCAAAAGCACCCCGGGT

Product: cytosine/adenosine deaminase

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MYESLNDRILSDFFKSMKDLLLKEREEVPSFTRIYQKEELISETFNEVEKHLDSSFHSEILCIRDAKKKLKTRYLTDCTL
ITSLEPCLMCTGTILLSRIPKIIYLLPARQGEGISSLSIEMIYSRNFFPELICIPAEISKNAFKSFFKIRRKKFN

Sequences:

>Translated_155_residues
MYESLNDRILSDFFKSMKDLLLKEREEVPSFTRIYQKEELISETFNEVEKHLDSSFHSEILCIRDAKKKLKTRYLTDCTL
ITSLEPCLMCTGTILLSRIPKIIYLLPARQGEGISSLSIEMIYSRNFFPELICIPAEISKNAFKSFFKIRRKKFN
>Mature_155_residues
MYESLNDRILSDFFKSMKDLLLKEREEVPSFTRIYQKEELISETFNEVEKHLDSSFHSEILCIRDAKKKLKTRYLTDCTL
ITSLEPCLMCTGTILLSRIPKIIYLLPARQGEGISSLSIEMIYSRNFFPELICIPAEISKNAFKSFFKIRRKKFN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 18219; Mature: 18219

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYESLNDRILSDFFKSMKDLLLKEREEVPSFTRIYQKEELISETFNEVEKHLDSSFHSEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCIRDAKKKLKTRYLTDCTLITSLEPCLMCTGTILLSRIPKIIYLLPARQGEGISSLSIE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHH
MIYSRNFFPELICIPAEISKNAFKSFFKIRRKKFN
HHHCCCCCCHHEEECHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYESLNDRILSDFFKSMKDLLLKEREEVPSFTRIYQKEELISETFNEVEKHLDSSFHSEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCIRDAKKKLKTRYLTDCTLITSLEPCLMCTGTILLSRIPKIIYLLPARQGEGISSLSIE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHH
MIYSRNFFPELICIPAEISKNAFKSFFKIRRKKFN
HHHCCCCCCHHEEECHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]