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The map label for this gene is lyx [H]

Identifier: 116249425

GI number: 116249425

Start: 830660

End: 832189

Strand: Direct

Name: lyx [H]

Synonym: pRL120763

Alternate gene names: 116249425

Gene position: 830660-832189 (Clockwise)

Preceding gene: 116249424

Following gene: 116249426

Centisome position: 95.48

GC content: 65.95

Gene sequence:

>1530_bases
ATGGGAAACTATCTTTTGGGGCTCGACGCCGGAAACACCGTCATCAAGGCGGTGATTTTCGACCGGGCGGGCAACGAGAT
CGCAGCTGCGTCCGAAGAAGGACACAGCCGCATGCCGAGCCCGGGGCATGTCGAGCGGGGTCTGGACGAATTATGGGCGA
ATGCCCGCCAGGTCATCCGCGCTTGCATCGAAAAGGCAGAGATCCAGCCGGAGGAAATTGCCGCGATCGGTTGCGCCGGG
CATGGCAACGGTCTCTATGCGCTTGATCGCGACGGCGCTCCGCTGCTCGGCATCCAGTCGCTCGACACGCGGGCGGCCGG
GCTGGTCGATGAATGGCGAGAGGCCGGCGTTGGTGACCGGACCTATCCGATTGCTCGCCAGCGTCCGTGGCCATCCCAGA
CGCCGACATTGCTTGCCTGGCTGAAGCGTCATCGGCCGGATCTGTTCAACCGCATCGGTACGGTGTTCTTCTCCAAGGAT
TTCGTCGTCAACCGCCTGACCGGCCGCCGCGTCAGCGAGGTGTCCGACATGTCGGGGGCCGGTCTGCTCGATCTTGCCGC
GCGCCGCTACGACAAGGGGCTGATGGAAGCCTATGGATTGGACGATTGCATGGACCTCTTGCCGCCGCTCATCGAAAGCG
CCGACATTGCCGGTACGATAACGGACGAGGTGGCGACGCAAACCGGGCTTGCCGCCGGTACGCCTGTGGTCGGCGGGCTG
TTCGACGTTGTCGCCTCGGCGCTCGGCTCGGGCGTTTCGCGCACTGGCAGCGCCTCGATCATTGCCGGCACCTGGAGCAT
CAACCAGGTCGTTATAGATAGTCCCGACCTCGACGGGCCGGTCTTCATGTCCTCGACCTTCGATCGCAGCCGTTACATGG
CGATGGAGAACAGCGCCACCTCGGCTGCCAATCTCGAATGGCTGGTGCGGGAGTTTTTCGAAGGCGTGCATGCGGAAGGC
GTTTCGCCCTTCGATGCCTGCTGCGCACTGGCCGGGGCGATCGAGCCCGCGGCAGACGACCCGCTCTACCATCCGTATCT
CTATGGCGCCCAGCAGGACGGCCACGCACGCGCCGGCTTCTACGGCATTGCCGGCTGGCACACCAAGGGGCATCTGGTTC
GCGCGCTTCTCGAGGGTGTCGCCTTCGGTCATCGCCAGCACATCGAGACGATCCGAAAGGCCGGCGCGGTGTTCAACGAG
GCGGTGCTCTCCGGCGGCGGCTCGCGCAGCCTGATCTGGCCGCAGATCTTTGCCGATGTGCTCGGCGTACCCGTCACCGT
CGCCCGCTCGCGCGAAACCGGTGCACTGGGGGCGGCGATCGCGGCCGGAACCGGTGTCGGCGTCTTCGCGGACTTCGGCG
CTGGTGCTGCGGCCATGGTCCGGACCGAGCGCCATTATCGCCCGGATGTCTCGCTTGAGGCGCATTACGCGCGGCGCTAC
GCTCTCTATCAGGATATCGCCGAAGCGATGGCACCGCTCTGGCGGCGTCTGACGGCGGTCCCGCCGGCGGCAGCGGGGGC
GGCGGCGTGA

Upstream 100 bases:

>100_bases
GGCTGATGGCGATCGTGCACGAGGGTGCGAGCGGCGAACAGGCCTTTGCGCTCTACCAGCAGCGCTGAGCAGCGATCTCG
AACCTTGGGAGGGGTTCTGC

Downstream 100 bases:

>100_bases
ATATGCGTGTGAATGATGCAGCCATTGATGCGGCCATTGATGCAGGAACCTACGATTTCATCATCGTCGGCGCGGGATCG
GCGGGATGCGTTCTGGCCAA

Product: putative L-xylulose kinase

Products: NA

Alternate protein names: L-xylulokinase [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MGNYLLGLDAGNTVIKAVIFDRAGNEIAAASEEGHSRMPSPGHVERGLDELWANARQVIRACIEKAEIQPEEIAAIGCAG
HGNGLYALDRDGAPLLGIQSLDTRAAGLVDEWREAGVGDRTYPIARQRPWPSQTPTLLAWLKRHRPDLFNRIGTVFFSKD
FVVNRLTGRRVSEVSDMSGAGLLDLAARRYDKGLMEAYGLDDCMDLLPPLIESADIAGTITDEVATQTGLAAGTPVVGGL
FDVVASALGSGVSRTGSASIIAGTWSINQVVIDSPDLDGPVFMSSTFDRSRYMAMENSATSAANLEWLVREFFEGVHAEG
VSPFDACCALAGAIEPAADDPLYHPYLYGAQQDGHARAGFYGIAGWHTKGHLVRALLEGVAFGHRQHIETIRKAGAVFNE
AVLSGGGSRSLIWPQIFADVLGVPVTVARSRETGALGAAIAAGTGVGVFADFGAGAAAMVRTERHYRPDVSLEAHYARRY
ALYQDIAEAMAPLWRRLTAVPPAAAGAAA

Sequences:

>Translated_509_residues
MGNYLLGLDAGNTVIKAVIFDRAGNEIAAASEEGHSRMPSPGHVERGLDELWANARQVIRACIEKAEIQPEEIAAIGCAG
HGNGLYALDRDGAPLLGIQSLDTRAAGLVDEWREAGVGDRTYPIARQRPWPSQTPTLLAWLKRHRPDLFNRIGTVFFSKD
FVVNRLTGRRVSEVSDMSGAGLLDLAARRYDKGLMEAYGLDDCMDLLPPLIESADIAGTITDEVATQTGLAAGTPVVGGL
FDVVASALGSGVSRTGSASIIAGTWSINQVVIDSPDLDGPVFMSSTFDRSRYMAMENSATSAANLEWLVREFFEGVHAEG
VSPFDACCALAGAIEPAADDPLYHPYLYGAQQDGHARAGFYGIAGWHTKGHLVRALLEGVAFGHRQHIETIRKAGAVFNE
AVLSGGGSRSLIWPQIFADVLGVPVTVARSRETGALGAAIAAGTGVGVFADFGAGAAAMVRTERHYRPDVSLEAHYARRY
ALYQDIAEAMAPLWRRLTAVPPAAAGAAA
>Mature_508_residues
GNYLLGLDAGNTVIKAVIFDRAGNEIAAASEEGHSRMPSPGHVERGLDELWANARQVIRACIEKAEIQPEEIAAIGCAGH
GNGLYALDRDGAPLLGIQSLDTRAAGLVDEWREAGVGDRTYPIARQRPWPSQTPTLLAWLKRHRPDLFNRIGTVFFSKDF
VVNRLTGRRVSEVSDMSGAGLLDLAARRYDKGLMEAYGLDDCMDLLPPLIESADIAGTITDEVATQTGLAAGTPVVGGLF
DVVASALGSGVSRTGSASIIAGTWSINQVVIDSPDLDGPVFMSSTFDRSRYMAMENSATSAANLEWLVREFFEGVHAEGV
SPFDACCALAGAIEPAADDPLYHPYLYGAQQDGHARAGFYGIAGWHTKGHLVRALLEGVAFGHRQHIETIRKAGAVFNEA
VLSGGGSRSLIWPQIFADVLGVPVTVARSRETGALGAAIAAGTGVGVFADFGAGAAAMVRTERHYRPDVSLEAHYARRYA
LYQDIAEAMAPLWRRLTAVPPAAAGAAA

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=467, Percent_Identity=23.5546038543897, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI189409120, Length=467, Percent_Identity=23.5546038543897, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4504007, Length=467, Percent_Identity=23.5546038543897, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI41393575, Length=458, Percent_Identity=23.1441048034935, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790005, Length=494, Percent_Identity=34.2105263157895, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI1787789, Length=504, Percent_Identity=30.952380952381, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789987, Length=509, Percent_Identity=27.5049115913556, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1789168, Length=479, Percent_Identity=25.8872651356994, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789138, Length=504, Percent_Identity=23.015873015873, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=454, Percent_Identity=24.4493392070485, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321755, Length=496, Percent_Identity=25.2016129032258, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.53 [H]

Molecular weight: Translated: 54067; Mature: 53935

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNYLLGLDAGNTVIKAVIFDRAGNEIAAASEEGHSRMPSPGHVERGLDELWANARQVIR
CCCEEEEECCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ACIEKAEIQPEEIAAIGCAGHGNGLYALDRDGAPLLGIQSLDTRAAGLVDEWREAGVGDR
HHHHHHCCCHHHEEEEEECCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCCCC
TYPIARQRPWPSQTPTLLAWLKRHRPDLFNRIGTVFFSKDFVVNRLTGRRVSEVSDMSGA
CCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHCCCCC
GLLDLAARRYDKGLMEAYGLDDCMDLLPPLIESADIAGTITDEVATQTGLAAGTPVVGGL
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHH
FDVVASALGSGVSRTGSASIIAGTWSINQVVIDSPDLDGPVFMSSTFDRSRYMAMENSAT
HHHHHHHHCCCCCCCCCCEEEEEEEEECEEEECCCCCCCCEEECCCCCHHHHEEECCCCC
SAANLEWLVREFFEGVHAEGVSPFDACCALAGAIEPAADDPLYHPYLYGAQQDGHARAGF
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCE
YGIAGWHTKGHLVRALLEGVAFGHRQHIETIRKAGAVFNEAVLSGGGSRSLIWPQIFADV
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LGVPVTVARSRETGALGAAIAAGTGVGVFADFGAGAAAMVRTERHYRPDVSLEAHYARRY
HCCCEEEECCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
ALYQDIAEAMAPLWRRLTAVPPAAAGAAA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GNYLLGLDAGNTVIKAVIFDRAGNEIAAASEEGHSRMPSPGHVERGLDELWANARQVIR
CCEEEEECCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ACIEKAEIQPEEIAAIGCAGHGNGLYALDRDGAPLLGIQSLDTRAAGLVDEWREAGVGDR
HHHHHHCCCHHHEEEEEECCCCCCEEEECCCCCCEEECCCCCHHHHHHHHHHHHCCCCCC
TYPIARQRPWPSQTPTLLAWLKRHRPDLFNRIGTVFFSKDFVVNRLTGRRVSEVSDMSGA
CCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHCCCCC
GLLDLAARRYDKGLMEAYGLDDCMDLLPPLIESADIAGTITDEVATQTGLAAGTPVVGGL
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHH
FDVVASALGSGVSRTGSASIIAGTWSINQVVIDSPDLDGPVFMSSTFDRSRYMAMENSAT
HHHHHHHHCCCCCCCCCCEEEEEEEEECEEEECCCCCCCCEEECCCCCHHHHEEECCCCC
SAANLEWLVREFFEGVHAEGVSPFDACCALAGAIEPAADDPLYHPYLYGAQQDGHARAGF
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCE
YGIAGWHTKGHLVRALLEGVAFGHRQHIETIRKAGAVFNEAVLSGGGSRSLIWPQIFADV
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LGVPVTVARSRETGALGAAIAAGTGVGVFADFGAGAAAMVRTERHYRPDVSLEAHYARRY
HCCCEEEECCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
ALYQDIAEAMAPLWRRLTAVPPAAAGAAA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]