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The map label for this gene is glpD [H]

Identifier: 116249423

GI number: 116249423

Start: 828064

End: 829812

Strand: Direct

Name: glpD [H]

Synonym: pRL120761

Alternate gene names: 116249423

Gene position: 828064-829812 (Clockwise)

Preceding gene: 116249422

Following gene: 116249424

Centisome position: 95.18

GC content: 63.12

Gene sequence:

>1749_bases
ATGAAACGGCAAGAGATATTGGACGGGCTCCGCCAGAGCCCGAAGGTGGACGTCTGTGTCATCGGCGGCGGCATCAACGG
CATCAGCGTCTTTCGGGAGCTGTCGCTGCAGGGGCTGAACGTGCTGCTCGTCGAGAAACACGACTATTGCTCCGGGGCCA
GTTCGGCGCTGTCGCGCATGGTGCATGGCGGGCTTCGCTATCTTGAAAACGGCGAATTCAAGCTGGTGCAGGAATCGCTG
GTCGAGCGGGACCGGCTGTTGCGCAATGCGCCGCATTACGTCGCGCCGCTGCCGACGACGGTGCCGGTGTTCGATATCTT
TTCCGGCCTCGGCAATGGCATCGTCCGCTTCCTGGGTCTCAGCCGCCGCCCGAGCCGGCGTGGCGCTATCGCCATCAAGG
CAGGCCTGAGCATCTATGATTTCCTGACCCGCAAGCGGGCACTGATGCCGCGCCACCAGTTTCGCGGCCGACGCACGACG
CTTGCCAAGTGGCCGGCGCTCAATCCCGACATCAAGAGTTCCGCCACCTATTTCGACGCCTGGGTCAGCCATCCGGAGCG
GCTCGGCATCGAGCTTCTGCAGGATGGTCTATCAGCAGAGTTCGGGGCGATGGCGCTGAACTATGCGGAACTGCGGCGGA
CAGAGGATGGTCAGTACCGTGTCGAAGACCAGATCGGCGGCGCGTCCGTTGCCGTCAAACCGGCGCTGATCATCAACGCC
ACCGGCGGCTGGATCGACATCGCCAATCAGACCCTGTTTTCGCCGGAAGCGCGGCCGGCTCCGCTGATGGGCGGCACAAA
GGGCTCGCATCTGATCGTCGACAATGCGGACCTGCGCGACGCACTCGCCGATCACATGATCTACTATGAAAACGAGGACG
GGCGGATCTGCATCCTGTTTCCCTATCTCGGCAAGGTTCTCGTCGGTTCCACCGATATCCGCGTCGACGATCCGGAAACG
GTGCGCTGCGAGGCGGACGAGCGGGACTATATCCTGCAATCGCTCGCCTTCGTGCTGCCTGATATCGCCGTCCGGCCGGA
ACAGATCGTTTTCCAGTTTTCCGGCGTGCGGCCGCTGCCGGCCAGCACCGACAGTTTTACCGGGCGCATTCCGCGCGATC
ATTTCTGCACGGTCGTAGAGCCGAAGGATGGCGGCCCACCGGTTCTGTGCATGATCGGCGGCAAGTGGACGACATTCCGG
TCCTTCGGGGAACTGGCCGCCGACATGGCTCTGGAACGGCTAGACAGGCAGCGCCGTGTTGCGACAACCGATCGGCCGAT
CGGCGGCGGGCAGGCATTTCCCGCCAACGCGCCTGTCTGGCTTGCGCAGGCGGCGGCCAGCAAAGGCCTTTCCATCCGGC
GCATGGCTGAGCTGTTTGCCCGATACGGCACGGACGCGGAGGCGGTTGCCGGTTTCATCGCGGCCGGCCCCGATGCAGTG
CTGCCGCACGCCGGCTACTCGGTGCGCGAATTGCAGTTCCTGATCCGCGGTGAAGCGGTGGAACATCTGGACGACCTGCT
TTTACGGCGCACAACGCTTGCCGTTTCGGGCGAGCTTACGCTCGACATGATGGATGCCGTACTCGACCTGCTGGCGCAGG
AAAAGCACTGGACGCTCGCGCATCACGCCCGTGAGCGCGACCGTTTTCTCACCCTTCTCACCGAACGCCACGGCGTCGAC
GAAGACATGCTTTCCGCAAGGAACGAACCAAGGAGCATAGAATGCGACACAACAGCAAAGTCCGGATGA

Upstream 100 bases:

>100_bases
GCGGGCCGGGACCGTCCGGCTGGATGCGGCCGATCTTGCGGCCATCGATACGGCCATAGCGGCGAAACTGACTGACATGG
ACAGGTAGCGGATCGCCATC

Downstream 100 bases:

>100_bases
ACCGGCTGTTCGGCGGCGGCCGCTGCCTCGACGTGGCGATCGATCACGGCGTCTGCAACGAACCGTCCTTCCTCAACGGG
CTGGAGGATATTCAGGCCGT

Product: putative glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MKRQEILDGLRQSPKVDVCVIGGGINGISVFRELSLQGLNVLLVEKHDYCSGASSALSRMVHGGLRYLENGEFKLVQESL
VERDRLLRNAPHYVAPLPTTVPVFDIFSGLGNGIVRFLGLSRRPSRRGAIAIKAGLSIYDFLTRKRALMPRHQFRGRRTT
LAKWPALNPDIKSSATYFDAWVSHPERLGIELLQDGLSAEFGAMALNYAELRRTEDGQYRVEDQIGGASVAVKPALIINA
TGGWIDIANQTLFSPEARPAPLMGGTKGSHLIVDNADLRDALADHMIYYENEDGRICILFPYLGKVLVGSTDIRVDDPET
VRCEADERDYILQSLAFVLPDIAVRPEQIVFQFSGVRPLPASTDSFTGRIPRDHFCTVVEPKDGGPPVLCMIGGKWTTFR
SFGELAADMALERLDRQRRVATTDRPIGGGQAFPANAPVWLAQAAASKGLSIRRMAELFARYGTDAEAVAGFIAAGPDAV
LPHAGYSVRELQFLIRGEAVEHLDDLLLRRTTLAVSGELTLDMMDAVLDLLAQEKHWTLAHHARERDRFLTLLTERHGVD
EDMLSARNEPRSIECDTTAKSG

Sequences:

>Translated_582_residues
MKRQEILDGLRQSPKVDVCVIGGGINGISVFRELSLQGLNVLLVEKHDYCSGASSALSRMVHGGLRYLENGEFKLVQESL
VERDRLLRNAPHYVAPLPTTVPVFDIFSGLGNGIVRFLGLSRRPSRRGAIAIKAGLSIYDFLTRKRALMPRHQFRGRRTT
LAKWPALNPDIKSSATYFDAWVSHPERLGIELLQDGLSAEFGAMALNYAELRRTEDGQYRVEDQIGGASVAVKPALIINA
TGGWIDIANQTLFSPEARPAPLMGGTKGSHLIVDNADLRDALADHMIYYENEDGRICILFPYLGKVLVGSTDIRVDDPET
VRCEADERDYILQSLAFVLPDIAVRPEQIVFQFSGVRPLPASTDSFTGRIPRDHFCTVVEPKDGGPPVLCMIGGKWTTFR
SFGELAADMALERLDRQRRVATTDRPIGGGQAFPANAPVWLAQAAASKGLSIRRMAELFARYGTDAEAVAGFIAAGPDAV
LPHAGYSVRELQFLIRGEAVEHLDDLLLRRTTLAVSGELTLDMMDAVLDLLAQEKHWTLAHHARERDRFLTLLTERHGVD
EDMLSARNEPRSIECDTTAKSG
>Mature_582_residues
MKRQEILDGLRQSPKVDVCVIGGGINGISVFRELSLQGLNVLLVEKHDYCSGASSALSRMVHGGLRYLENGEFKLVQESL
VERDRLLRNAPHYVAPLPTTVPVFDIFSGLGNGIVRFLGLSRRPSRRGAIAIKAGLSIYDFLTRKRALMPRHQFRGRRTT
LAKWPALNPDIKSSATYFDAWVSHPERLGIELLQDGLSAEFGAMALNYAELRRTEDGQYRVEDQIGGASVAVKPALIINA
TGGWIDIANQTLFSPEARPAPLMGGTKGSHLIVDNADLRDALADHMIYYENEDGRICILFPYLGKVLVGSTDIRVDDPET
VRCEADERDYILQSLAFVLPDIAVRPEQIVFQFSGVRPLPASTDSFTGRIPRDHFCTVVEPKDGGPPVLCMIGGKWTTFR
SFGELAADMALERLDRQRRVATTDRPIGGGQAFPANAPVWLAQAAASKGLSIRRMAELFARYGTDAEAVAGFIAAGPDAV
LPHAGYSVRELQFLIRGEAVEHLDDLLLRRTTLAVSGELTLDMMDAVLDLLAQEKHWTLAHHARERDRFLTLLTERHGVD
EDMLSARNEPRSIECDTTAKSG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=572, Percent_Identity=26.2237762237762, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI285002231, Length=572, Percent_Identity=26.2237762237762, Blast_Score=143, Evalue=5e-34,
Organism=Escherichia coli, GI2367226, Length=484, Percent_Identity=29.9586776859504, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1788574, Length=409, Percent_Identity=27.6283618581907, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17509253, Length=600, Percent_Identity=24.6666666666667, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI115534726, Length=430, Percent_Identity=27.6744186046512, Blast_Score=119, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6322036, Length=632, Percent_Identity=25.9493670886076, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI161077125, Length=590, Percent_Identity=24.406779661017, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653942, Length=590, Percent_Identity=24.406779661017, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653944, Length=590, Percent_Identity=24.406779661017, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI20130025, Length=590, Percent_Identity=24.406779661017, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24586295, Length=585, Percent_Identity=23.5897435897436, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19921278, Length=577, Percent_Identity=22.1837088388215, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 64178; Mature: 64178

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQEILDGLRQSPKVDVCVIGGGINGISVFRELSLQGLNVLLVEKHDYCSGASSALSRM
CCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
VHGGLRYLENGEFKLVQESLVERDRLLRNAPHYVAPLPTTVPVFDIFSGLGNGIVRFLGL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCC
SRRPSRRGAIAIKAGLSIYDFLTRKRALMPRHQFRGRRTTLAKWPALNPDIKSSATYFDA
CCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHCCCCCEEEECCCCCCCCCCCCHHHHH
WVSHPERLGIELLQDGLSAEFGAMALNYAELRRTEDGQYRVEDQIGGASVAVKPALIINA
HHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCEEEEEC
TGGWIDIANQTLFSPEARPAPLMGGTKGSHLIVDNADLRDALADHMIYYENEDGRICILF
CCCEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCEEEEECCCCCEEEEH
PYLGKVLVGSTDIRVDDPETVRCEADERDYILQSLAFVLPDIAVRPEQIVFQFSGVRPLP
HHHHHHHCCCCCEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCC
ASTDSFTGRIPRDHFCTVVEPKDGGPPVLCMIGGKWTTFRSFGELAADMALERLDRQRRV
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATTDRPIGGGQAFPANAPVWLAQAAASKGLSIRRMAELFARYGTDAEAVAGFIAAGPDAV
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
LPHAGYSVRELQFLIRGEAVEHLDDLLLRRTTLAVSGELTLDMMDAVLDLLAQEKHWTLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHH
HHARERDRFLTLLTERHGVDEDMLSARNEPRSIECDTTAKSG
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKRQEILDGLRQSPKVDVCVIGGGINGISVFRELSLQGLNVLLVEKHDYCSGASSALSRM
CCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
VHGGLRYLENGEFKLVQESLVERDRLLRNAPHYVAPLPTTVPVFDIFSGLGNGIVRFLGL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCC
SRRPSRRGAIAIKAGLSIYDFLTRKRALMPRHQFRGRRTTLAKWPALNPDIKSSATYFDA
CCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHCCCCCEEEECCCCCCCCCCCCHHHHH
WVSHPERLGIELLQDGLSAEFGAMALNYAELRRTEDGQYRVEDQIGGASVAVKPALIINA
HHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCEEEEEC
TGGWIDIANQTLFSPEARPAPLMGGTKGSHLIVDNADLRDALADHMIYYENEDGRICILF
CCCEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCEEEEECCCCCEEEEH
PYLGKVLVGSTDIRVDDPETVRCEADERDYILQSLAFVLPDIAVRPEQIVFQFSGVRPLP
HHHHHHHCCCCCEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCC
ASTDSFTGRIPRDHFCTVVEPKDGGPPVLCMIGGKWTTFRSFGELAADMALERLDRQRRV
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATTDRPIGGGQAFPANAPVWLAQAAASKGLSIRRMAELFARYGTDAEAVAGFIAAGPDAV
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
LPHAGYSVRELQFLIRGEAVEHLDDLLLRRTTLAVSGELTLDMMDAVLDLLAQEKHWTLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHH
HHARERDRFLTLLTERHGVDEDMLSARNEPRSIECDTTAKSG
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]