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The map label for this gene is lsrR [H]

Identifier: 116249421

GI number: 116249421

Start: 826055

End: 827059

Strand: Direct

Name: lsrR [H]

Synonym: pRL120759

Alternate gene names: 116249421

Gene position: 826055-827059 (Clockwise)

Preceding gene: 116249420

Following gene: 116249422

Centisome position: 94.95

GC content: 62.69

Gene sequence:

>1005_bases
ATGCCGATAGCCAAGCTCAAACCCGCAAATGCGCCGCGCGAGGAAATCGTCATCGCCCGGCAGATGCACCAGGCTCTGGT
CCTGCATTTCCTCGAGGGACTGACACAGGCGCAGATTGCCGATCAGCTCGGCATCTCGCACGCCACCGTCAACCGGCTGA
TCAAGCGCGGCCGCCAGCTCGGCCTGGTCGAGATCAAGATCAAGTCGCCGGTCGAGCCGCTGGTCGATATGGAAGAACGG
CTACGCGCACTTGGCGGCATCGGCCGCGCAGTGGTGGTGCCGACAGTGTCCGACAATCCGCAGACGGCGCTTCAAGCCGT
CGGCGAAGCGGCTGCAAGGTTGCTGCTGGAAGAGATCACCGACGGCGATACGATCTGCATCACTGGCGGCAAAGGGGTGA
GCGCCGTCGTTGCCGGTCTGCAGCCGCCGCGTCGGTTCAATGTCGAGGTCATTCCAGCAACCGGCTGCGTCCAGGGTAAA
CACTATACCGACGTCAATCATGTCTCGACCTTGATGGCCGATCGGCTTGGGGGACGTTCCTACCAGATCCATGCGCCCCT
CTTTGCCGATGATGCCGAGCAGCGGGCGATGCTGATCAACATGCGTTCCGTCGCAGACGTTTTCAAACGGGCGCGCGAAG
CGAAGGTAGCGGTGGTCGGCATCGGCTCGATCCTGTCGGACGATTCGAGCTATTACGACCTGCATCCGTCCTCGAGCACA
GACCGCGCTGCGATCGAGCGCTCCGGCGCCTCCTGCGAATTGCTGGCGCATCTGCTCGATGATCATGGCCAGGTCTGCGA
CTACAGCCTCAACCGTTCGCTGGTGTCGCTGACGCTGCCGGAATTCGCCTCGATCCCCACCAAGATCGGTGTGGCGAGCG
GGCCGAACAAGGCAGGCCCGATCCTCAGCGTTCTGCGCGGCAATCATCTGGATACGCTGGTGACCGATGAGGCGACGGGT
GCGCGGGTGCTGGCACTGGCGAATGGCGAAGGAAAATGGGCATGA

Upstream 100 bases:

>100_bases
CTCGACGTGTCTGTCTATTGGCAAGACATGATCAAAGGCTGCATTCTGCTTGCCGCCGTCTCGATCGACCATTTCCTGCA
CAAGCGGAAGGCTGCCTGAT

Downstream 100 bases:

>100_bases
GCGGACAGCAATTGACACGTGAGATCGGCAAATCGGGCGTTTCCGCCTCGGCGGTGGGATTGGGCACCTGGGCGATCGGC
GGCTGGATGTGGGGCGGAAC

Product: putative transcriptional regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MPIAKLKPANAPREEIVIARQMHQALVLHFLEGLTQAQIADQLGISHATVNRLIKRGRQLGLVEIKIKSPVEPLVDMEER
LRALGGIGRAVVVPTVSDNPQTALQAVGEAAARLLLEEITDGDTICITGGKGVSAVVAGLQPPRRFNVEVIPATGCVQGK
HYTDVNHVSTLMADRLGGRSYQIHAPLFADDAEQRAMLINMRSVADVFKRAREAKVAVVGIGSILSDDSSYYDLHPSSST
DRAAIERSGASCELLAHLLDDHGQVCDYSLNRSLVSLTLPEFASIPTKIGVASGPNKAGPILSVLRGNHLDTLVTDEATG
ARVLALANGEGKWA

Sequences:

>Translated_334_residues
MPIAKLKPANAPREEIVIARQMHQALVLHFLEGLTQAQIADQLGISHATVNRLIKRGRQLGLVEIKIKSPVEPLVDMEER
LRALGGIGRAVVVPTVSDNPQTALQAVGEAAARLLLEEITDGDTICITGGKGVSAVVAGLQPPRRFNVEVIPATGCVQGK
HYTDVNHVSTLMADRLGGRSYQIHAPLFADDAEQRAMLINMRSVADVFKRAREAKVAVVGIGSILSDDSSYYDLHPSSST
DRAAIERSGASCELLAHLLDDHGQVCDYSLNRSLVSLTLPEFASIPTKIGVASGPNKAGPILSVLRGNHLDTLVTDEATG
ARVLALANGEGKWA
>Mature_333_residues
PIAKLKPANAPREEIVIARQMHQALVLHFLEGLTQAQIADQLGISHATVNRLIKRGRQLGLVEIKIKSPVEPLVDMEERL
RALGGIGRAVVVPTVSDNPQTALQAVGEAAARLLLEEITDGDTICITGGKGVSAVVAGLQPPRRFNVEVIPATGCVQGKH
YTDVNHVSTLMADRLGGRSYQIHAPLFADDAEQRAMLINMRSVADVFKRAREAKVAVVGIGSILSDDSSYYDLHPSSSTD
RAAIERSGASCELLAHLLDDHGQVCDYSLNRSLVSLTLPEFASIPTKIGVASGPNKAGPILSVLRGNHLDTLVTDEATGA
RVLALANGEGKWA

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=303, Percent_Identity=29.042904290429, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082414, Length=311, Percent_Identity=23.4726688102894, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35613; Mature: 35482

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAKLKPANAPREEIVIARQMHQALVLHFLEGLTQAQIADQLGISHATVNRLIKRGRQL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GLVEIKIKSPVEPLVDMEERLRALGGIGRAVVVPTVSDNPQTALQAVGEAAARLLLEEIT
CEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHC
DGDTICITGGKGVSAVVAGLQPPRRFNVEVIPATGCVQGKHYTDVNHVSTLMADRLGGRS
CCCEEEEECCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCE
YQIHAPLFADDAEQRAMLINMRSVADVFKRAREAKVAVVGIGSILSDDSSYYDLHPSSST
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECHHHCCCCCEEEECCCCCC
DRAAIERSGASCELLAHLLDDHGQVCDYSLNRSLVSLTLPEFASIPTKIGVASGPNKAGP
CHHHHHCCCCHHHHHHHHHHCCCCEECHHCCCCEEEEECHHHHCCCCCCCCCCCCCCCCH
ILSVLRGNHLDTLVTDEATGARVLALANGEGKWA
HHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
PIAKLKPANAPREEIVIARQMHQALVLHFLEGLTQAQIADQLGISHATVNRLIKRGRQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
GLVEIKIKSPVEPLVDMEERLRALGGIGRAVVVPTVSDNPQTALQAVGEAAARLLLEEIT
CEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHC
DGDTICITGGKGVSAVVAGLQPPRRFNVEVIPATGCVQGKHYTDVNHVSTLMADRLGGRS
CCCEEEEECCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCE
YQIHAPLFADDAEQRAMLINMRSVADVFKRAREAKVAVVGIGSILSDDSSYYDLHPSSST
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECHHHCCCCCEEEECCCCCC
DRAAIERSGASCELLAHLLDDHGQVCDYSLNRSLVSLTLPEFASIPTKIGVASGPNKAGP
CHHHHHCCCCHHHHHHHHHHCCCCEECHHCCCCEEEEECHHHHCCCCCCCCCCCCCCCCH
ILSVLRGNHLDTLVTDEATGARVLALANGEGKWA
HHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA