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The map label for this gene is opuCB [H]

Identifier: 116249415

GI number: 116249415

Start: 819865

End: 820500

Strand: Direct

Name: opuCB [H]

Synonym: pRL120753

Alternate gene names: 116249415

Gene position: 819865-820500 (Clockwise)

Preceding gene: 116249414

Following gene: 116249416

Centisome position: 94.24

GC content: 58.96

Gene sequence:

>636_bases
ATGATGAAATGGGTCCCTAAACACCTCGACCGGCTATTCGAAGCGCTGTTGGAGCACCTGTATCTCGTTTTTTCCTCGGT
CGGCATTGCCCTGGTGATCTCGCTGATCGTCGGGATATGGGCGGCAAGGCGACCGCGGAGCTTCGCGGTTATCATCATCT
TCACCGGTATCTTGTTCGCCGTGCCGAGCCTGGCGCTGTTTGCGCTTCTCATTCCCATTATGGGGATCGGGGCGGCACCT
GCCATTACCGGTCTTGCCGCCTACTCGCTGATGATCCTGATCCGCAATATCGGCATGGGGTTTCAGGCAATTCCGCGTGA
CATACTCGAAGCTGCCGATGGCATGGGCTACGGCACCGCGCGCCGGATCTGGGAGGTCGAGCTGCCGCTGGCGATGCCCT
ATATCGTCGGCGGTATCCGCATTGCCATGGTGACGGTCATCGGCATCGCGACCGTTGCCGCCTATATCAATGCCGGCGGC
CTCGGCGTCATCATTTTCGAAGGCATCGACCAGCGGTTTCCCGAAAAGATCATCGCCGGCGGGCTGCTGACGTCATTTCT
GGCGCTCTTTGCCGACTACTGTTTTGCATCCTTCGAAAAGCTGCTGCGCCGGCGCAGTGGAGGTAAAGCAGCATGA

Upstream 100 bases:

>100_bases
TCGGCCTACGATGTCCTGCCGCAGAGAGCCGACGACGCCGATCGCAGATTGGGGATCTCATGGTAGACAGGCGAACGAGC
GCTCGGACGCGGAGGTCTCG

Downstream 100 bases:

>100_bases
TCGTTATCGATGCATTCAGCTGGATCTTCAATAACTCCGGTACCTTCTTCAACGCTTTCAATCGCCATCTTCTGATGTGC
GTCCTATCGCTTGGCATCGC

Product: putative permease component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MMKWVPKHLDRLFEALLEHLYLVFSSVGIALVISLIVGIWAARRPRSFAVIIIFTGILFAVPSLALFALLIPIMGIGAAP
AITGLAAYSLMILIRNIGMGFQAIPRDILEAADGMGYGTARRIWEVELPLAMPYIVGGIRIAMVTVIGIATVAAYINAGG
LGVIIFEGIDQRFPEKIIAGGLLTSFLALFADYCFASFEKLLRRRSGGKAA

Sequences:

>Translated_211_residues
MMKWVPKHLDRLFEALLEHLYLVFSSVGIALVISLIVGIWAARRPRSFAVIIIFTGILFAVPSLALFALLIPIMGIGAAP
AITGLAAYSLMILIRNIGMGFQAIPRDILEAADGMGYGTARRIWEVELPLAMPYIVGGIRIAMVTVIGIATVAAYINAGG
LGVIIFEGIDQRFPEKIIAGGLLTSFLALFADYCFASFEKLLRRRSGGKAA
>Mature_211_residues
MMKWVPKHLDRLFEALLEHLYLVFSSVGIALVISLIVGIWAARRPRSFAVIIIFTGILFAVPSLALFALLIPIMGIGAAP
AITGLAAYSLMILIRNIGMGFQAIPRDILEAADGMGYGTARRIWEVELPLAMPYIVGGIRIAMVTVIGIATVAAYINAGG
LGVIIFEGIDQRFPEKIIAGGLLTSFLALFADYCFASFEKLLRRRSGGKAA

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=221, Percent_Identity=34.3891402714932, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788449, Length=207, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789033, Length=179, Percent_Identity=30.1675977653631, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22754; Mature: 22754

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKWVPKHLDRLFEALLEHLYLVFSSVGIALVISLIVGIWAARRPRSFAVIIIFTGILFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VPSLALFALLIPIMGIGAAPAITGLAAYSLMILIRNIGMGFQAIPRDILEAADGMGYGTA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHH
RRIWEVELPLAMPYIVGGIRIAMVTVIGIATVAAYINAGGLGVIIFEGIDQRFPEKIIAG
HHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHH
GLLTSFLALFADYCFASFEKLLRRRSGGKAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMKWVPKHLDRLFEALLEHLYLVFSSVGIALVISLIVGIWAARRPRSFAVIIIFTGILFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VPSLALFALLIPIMGIGAAPAITGLAAYSLMILIRNIGMGFQAIPRDILEAADGMGYGTA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHH
RRIWEVELPLAMPYIVGGIRIAMVTVIGIATVAAYINAGGLGVIIFEGIDQRFPEKIIAG
HHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHH
GLLTSFLALFADYCFASFEKLLRRRSGGKAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]