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The map label for this gene is mdtA [H]

Identifier: 116249360

GI number: 116249360

Start: 753665

End: 754750

Strand: Direct

Name: mdtA [H]

Synonym: pRL120697

Alternate gene names: 116249360

Gene position: 753665-754750 (Clockwise)

Preceding gene: 116249359

Following gene: 116249361

Centisome position: 86.63

GC content: 64.64

Gene sequence:

>1086_bases
GTGATTATTCGTCCCAAGATAGTCGCACTGATGATGGGTACGGCCCTGATCTCCTCCTGCACGCCGCAGGAGGAAAGCAA
GGAGGAAGCGCCCCGTCCCGTGCTGTCGACGACGGTCAAGCCAACGTCGTCTTCGAGCTTAAGCCTGACCGGCACGATCG
AACCGACGATCGAGACCGAACTCGGCTTCCGGATTCTCGGGCGGATGATCGCCCGCAACGTCAATGTCGGCGATCTCGTC
AAGAAGGATGATGTTGTTGCCGCCATCGATCCGCTGGCGCTGGAGCTTGCCGTGCGCAACGCGCAGTCGGACGTAGAGAA
CAGCGACGCCCAGCTCAGGAACGCGGTGACCACAGAGCAGCGCCAGCGCGCGTTGCTGGAGTCGCGCTCAGGCACCGAAG
CCTCGCTCGAAGAGGCCGAACAGGCAAGGCGGACGGCGGCCGCAGCCGTCGCCAAGGCACAGGCCAATCTCGACAAGGCC
ACGGAGCAACTCGGCTACGCGCAGCTTCGGGCGGAATTCGACGGGGTGGTGACGGCGACCTCTGCTGAGGTCGGACAAGT
GGTGTCGGCCGGCCAGACGGTCGTGACCATCGCACGGCCGGATAAGCGCGATGCCGTGGTCGACGTACCCCAGGCAGCCG
CCCAGAAACTGAAGATCGGCGCGCCCTTCGAGGTGATGCTGCAGCTCGATCCGACCATCCGCACGTCCGGGATCGTGCGT
GAAATAGCACCAGAGGCGGAGACCTCCACCCGCACGAGCAGGACCAAGATCGCGCTGAGCGATCCTCCCGCGACCTTCCG
GCTGGGCTCGGTCATATCAGCCTCGGCAACCATTGCAGCCGATCCGCAGATCGTCCTGCCTTCCTCCGCAATCCTTGTCG
GCAGCGACGGCCCGAGCGTCTGGATCGTCGATGCGCCGGCCAGGAAGGTATCGCTTCGCCGCGTGAAGATCGACGGCGAC
GTCGAAGACGGCGGCAGCGTCCGCGTCACCGAGGGGCTCGCCCCCGGAGAAAGGGTCGTCGTGGCAGGCGTGCATAAACT
TGAAGATGGCCAGGCCATCAGGATCGACCAGGAGATCAGCCAGTGA

Upstream 100 bases:

>100_bases
TCGTCAAGTCAGGCGTGTCGGACGGAGAGGTCGTGGTGGCCGACGGAACCAAGTTCCTCAGGCCGGGTGAAATCGTGTCT
TATGTCAAGGAAGCTTCCAA

Downstream 100 bases:

>100_bases
AATCCTTCAACCTTTCCGACTGGGCGCTCGAACACCGTTCGCTCGTCTGGTACTTCCTGATCGTCTTCATTCTCGCAGGC
GCTTTCTCCTACGTGAAGCT

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MIIRPKIVALMMGTALISSCTPQEESKEEAPRPVLSTTVKPTSSSSLSLTGTIEPTIETELGFRILGRMIARNVNVGDLV
KKDDVVAAIDPLALELAVRNAQSDVENSDAQLRNAVTTEQRQRALLESRSGTEASLEEAEQARRTAAAAVAKAQANLDKA
TEQLGYAQLRAEFDGVVTATSAEVGQVVSAGQTVVTIARPDKRDAVVDVPQAAAQKLKIGAPFEVMLQLDPTIRTSGIVR
EIAPEAETSTRTSRTKIALSDPPATFRLGSVISASATIAADPQIVLPSSAILVGSDGPSVWIVDAPARKVSLRRVKIDGD
VEDGGSVRVTEGLAPGERVVVAGVHKLEDGQAIRIDQEISQ

Sequences:

>Translated_361_residues
MIIRPKIVALMMGTALISSCTPQEESKEEAPRPVLSTTVKPTSSSSLSLTGTIEPTIETELGFRILGRMIARNVNVGDLV
KKDDVVAAIDPLALELAVRNAQSDVENSDAQLRNAVTTEQRQRALLESRSGTEASLEEAEQARRTAAAAVAKAQANLDKA
TEQLGYAQLRAEFDGVVTATSAEVGQVVSAGQTVVTIARPDKRDAVVDVPQAAAQKLKIGAPFEVMLQLDPTIRTSGIVR
EIAPEAETSTRTSRTKIALSDPPATFRLGSVISASATIAADPQIVLPSSAILVGSDGPSVWIVDAPARKVSLRRVKIDGD
VEDGGSVRVTEGLAPGERVVVAGVHKLEDGQAIRIDQEISQ
>Mature_361_residues
MIIRPKIVALMMGTALISSCTPQEESKEEAPRPVLSTTVKPTSSSSLSLTGTIEPTIETELGFRILGRMIARNVNVGDLV
KKDDVVAAIDPLALELAVRNAQSDVENSDAQLRNAVTTEQRQRALLESRSGTEASLEEAEQARRTAAAAVAKAQANLDKA
TEQLGYAQLRAEFDGVVTATSAEVGQVVSAGQTVVTIARPDKRDAVVDVPQAAAQKLKIGAPFEVMLQLDPTIRTSGIVR
EIAPEAETSTRTSRTKIALSDPPATFRLGSVISASATIAADPQIVLPSSAILVGSDGPSVWIVDAPARKVSLRRVKIDGD
VEDGGSVRVTEGLAPGERVVVAGVHKLEDGQAIRIDQEISQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=377, Percent_Identity=24.4031830238727, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082036, Length=319, Percent_Identity=25.0783699059561, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081796, Length=238, Percent_Identity=26.890756302521, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38108; Mature: 38108

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIRPKIVALMMGTALISSCTPQEESKEEAPRPVLSTTVKPTSSSSLSLTGTIEPTIETE
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHEECCCCCCCCEEEEEEECCCCCHH
LGFRILGRMIARNVNVGDLVKKDDVVAAIDPLALELAVRNAQSDVENSDAQLRNAVTTEQ
HHHHHHHHHHHCCCCHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RQRALLESRSGTEASLEEAEQARRTAAAAVAKAQANLDKATEQLGYAQLRAEFDGVVTAT
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SAEVGQVVSAGQTVVTIARPDKRDAVVDVPQAAAQKLKIGAPFEVMLQLDPTIRTSGIVR
CHHHHHHHHCCCEEEEEECCCCCCCEEECCHHHHHHEECCCCEEEEEEECCCCCCCCHHH
EIAPEAETSTRTSRTKIALSDPPATFRLGSVISASATIAADPQIVLPSSAILVGSDGPSV
HHCCCCCCCCCCCCEEEEECCCCCCEECCCHHCCCEEEECCCEEECCCCEEEEECCCCEE
WIVDAPARKVSLRRVKIDGDVEDGGSVRVTEGLAPGERVVVAGVHKLEDGQAIRIDQEIS
EEEECCCCEEEEEEEEECCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCEEEECHHHC
Q
C
>Mature Secondary Structure
MIIRPKIVALMMGTALISSCTPQEESKEEAPRPVLSTTVKPTSSSSLSLTGTIEPTIETE
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHEECCCCCCCCEEEEEEECCCCCHH
LGFRILGRMIARNVNVGDLVKKDDVVAAIDPLALELAVRNAQSDVENSDAQLRNAVTTEQ
HHHHHHHHHHHCCCCHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RQRALLESRSGTEASLEEAEQARRTAAAAVAKAQANLDKATEQLGYAQLRAEFDGVVTAT
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SAEVGQVVSAGQTVVTIARPDKRDAVVDVPQAAAQKLKIGAPFEVMLQLDPTIRTSGIVR
CHHHHHHHHCCCEEEEEECCCCCCCEEECCHHHHHHEECCCCEEEEEEECCCCCCCCHHH
EIAPEAETSTRTSRTKIALSDPPATFRLGSVISASATIAADPQIVLPSSAILVGSDGPSV
HHCCCCCCCCCCCCEEEEECCCCCCEECCCHHCCCEEEECCCEEECCCCEEEEECCCCEE
WIVDAPARKVSLRRVKIDGDVEDGGSVRVTEGLAPGERVVVAGVHKLEDGQAIRIDQEIS
EEEECCCCEEEEEEEEECCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCEEEECHHHC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA