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The map label for this gene is groS [H]

Identifier: 116249308

GI number: 116249308

Start: 697820

End: 698134

Strand: Reverse

Name: groS [H]

Synonym: pRL120643

Alternate gene names: 116249308

Gene position: 698134-697820 (Counterclockwise)

Preceding gene: 116249309

Following gene: 116249307

Centisome position: 80.24

GC content: 60.32

Gene sequence:

>315_bases
ATGTCGTTCCGACCGCTTCATGACCGCATTCTCGTCCGCCGGGTCGATTCAGAGGAAAAGACCAAGGGCGGCATCATCAT
TCCCGACACCGCCAAGGAGAAGCCGCAAGAAGGTGAGGTCATCGCCGTCGGCCCCGGCGCACGCAACGAGGCCGGCCAGA
TCCTGGCGCTCGATGTCAAGCCCGGCGATCGCATCCTGTTCGGCAAGTGGTCCGGCACCGAGATCAAGATCAATGGCGAA
GACCTGCTGATCATGAAGGAAAGCGACGTGATGGGTATCATCGAAAGCCAGGGCGAAAAGAAGCAGGCCGCCTGA

Upstream 100 bases:

>100_bases
ATTCTCGCAAGGCTCGCGCGCGAGCCCCGCGCACCCGCCCGGACTGGTCATCCGGTCCGGCTAGGGAACCACGTCATCAC
TGTTGTCGATGGAGGAAGAT

Downstream 100 bases:

>100_bases
GATCCCTGCGGACATCCGTCAATGCCGGAACGTTTCAGCTTTTCATGGAAACGCAGAACCGCTCCAACCTTTTATTTCTA
ACGCAATTCCGAACGGAAAA

Product: putative 10 kDa chaperonin

Products: NA

Alternate protein names: GroES protein 5; Protein Cpn10 5 [H]

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MSFRPLHDRILVRRVDSEEKTKGGIIIPDTAKEKPQEGEVIAVGPGARNEAGQILALDVKPGDRILFGKWSGTEIKINGE
DLLIMKESDVMGIIESQGEKKQAA

Sequences:

>Translated_104_residues
MSFRPLHDRILVRRVDSEEKTKGGIIIPDTAKEKPQEGEVIAVGPGARNEAGQILALDVKPGDRILFGKWSGTEIKINGE
DLLIMKESDVMGIIESQGEKKQAA
>Mature_103_residues
SFRPLHDRILVRRVDSEEKTKGGIIIPDTAKEKPQEGEVIAVGPGARNEAGQILALDVKPGDRILFGKWSGTEIKINGED
LLIMKESDVMGIIESQGEKKQAA

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=36.6666666666667, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790585, Length=97, Percent_Identity=45.360824742268, Blast_Score=86, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=44.6808510638298, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324594, Length=94, Percent_Identity=34.0425531914894, Blast_Score=68, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=42.5531914893617, Blast_Score=79, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=40.8602150537634, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 11366; Mature: 11235

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRPLHDRILVRRVDSEEKTKGGIIIPDTAKEKPQEGEVIAVGPGARNEAGQILALDVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
PGDRILFGKWSGTEIKINGEDLLIMKESDVMGIIESQGEKKQAA
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SFRPLHDRILVRRVDSEEKTKGGIIIPDTAKEKPQEGEVIAVGPGARNEAGQILALDVK
CCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
PGDRILFGKWSGTEIKINGEDLLIMKESDVMGIIESQGEKKQAA
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8097179; 11481431 [H]