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The map label for this gene is cph2 [H]

Identifier: 116249172

GI number: 116249172

Start: 551340

End: 553268

Strand: Direct

Name: cph2 [H]

Synonym: pRL120508

Alternate gene names: 116249172

Gene position: 551340-553268 (Clockwise)

Preceding gene: 116249171

Following gene: 116249173

Centisome position: 63.37

GC content: 59.67

Gene sequence:

>1929_bases
ATGATTGGTTCGGTACATGTATTGGAAGGTGGATCCAACGCAGTGAATGGCATCTGGACGCAATTCGGTGGCAACCTGTC
ATTCGTGTGCCTGGCGATTTCGCTCTGGGCGCATTTCTCGATCCAATTTCAGAGTCGTTCGGTCACACAGGAAAAAATCG
CCTTCGGAATCATAGCCGGCGGCGCCTCCATCGGATCCATATTGCTGGCCGTCGAAGTCAATCCCGGCATCTATATCGAC
ATCCGCTTTTCGCCGCTTGCTTTGGCGGGCATGTTTGGCGGACCGATCGCAGCGGCTTTTGCCGCGTCGCTGGCGATGGT
CTTCCGCTTTGCTGTCGGCGGCACGGCAATGATCGATGGCCTGATCGCAATTGCTGTCGCAACCGGGATTGGCCTGGCTG
CCAATGTCTGGATCCGGAGGAGATCTGCCGAGCTCATGGACGTTGCGCTGCTGAGCCTCGCGCTCGGCGTTGCACTTATC
GTATTGATGGCGGTGCTTCCCACACTGGTGCACGCCCGCGTATTGGCCATCATCGGTCTGCCGATGACGGTATTGAACTG
CCTGGCGACGGCGCTGTGTGGTTTCGTTCTGTTGAAGACGCAGCAATGGGAGCTGGAGCGGAGCATCTTGGTGACCGCGT
TTTCGCAGTCGCCCGACTATCTCTACGTGAAGGACAGAAACAGCCGGTTCATCACCGTCAATGAAAATATGAGCCGCCTT
TTTCGTTTCAGAACCACGGCGGAGATGACCGGATTGTCGGATTTCAATCTTATATCGCGGCCGCGCGCCGAAGAATTTTA
CTATCTCGAACAGCAGGTCATGGACACCGGGGTGCCCCTGATCGACTCCGTCGAGCGTATCGAAGACAGATACCTGCTCG
CCTCCAAGGTGCCGCTGAAGGATAGGCAGGGACGGGTGATCGGCCTTGCCGGCGTCACGCGTGACGTGACGGAGCGGACT
GCCCTGGAGCGGGAATTGCGCAAGAGCAAGAACCTGTTGTCGCATGCGATGGCCGGCATGTCCGATGGCATCGCCATGTA
CGACAGCAAGGGTTTCCTCGTTTTTTGCAACGACCAGTATCGCACCGCCTTTCCGCTATCCGGGGACGCTCGCGTGGTTG
GTGCGCATATCAGCGACATCCTTCGCCGTGTTGCCGAAACCGGCGAGCGCACCGGTATCCCGGACAATGACCGCGAGGAG
TGGATCAAGGCCGCTAGCGCGACGTTGCATAGCAACAAGGACGAAGAGGTTCAGCTTCACAACGGCGACTGGCGCAGCAT
CCGGACAAGGCTTGCGGAAGACGGCACGGCGATGGCCGTTGTCTCGGACATCACGGCGACCAAGCAGGCGGAAATCGCCC
TCAGGCTGTCGGCGGAGCAACTGAGGAATCTCGCCGAGACCGATGGGCTCACCGGCATCGTCAATCGCCGGGCCTTCGAC
GAGGCTTTCGCCCGCGAGACCGCCGGCAGCGCCAGGAAAAACACGCCGTTCAGCCTTCTGATGGTCGATATCGACCGCTT
CAAGGCCTATAACGACACCTATGGTCATCCCGCCGGAGACCAATGCCTGCGTGTCGTCAGTAAGTGTCTGCGCCAGTCCG
TAAGCCGCCCGGCAGACATCGTCGCACGCTACGGCGGAGAGGAATTCGTGGTTCTGCTGCCTGCAACCAGTGCGAAAGGG
GCAATGATCGTTGCCGAGCAATTCGCGCGTCTCCTCAGCCAGGAGAATATCGTTCATACGGGCAGCGAATTCGGACGGGT
AACCGCCAGCATCGGCATATCCTGCGCGACGGGGGCCACGTTGAGGCTCAACCCGAACCGCCTCCTGATCGAGGCCGATG
CCGCGCTCTACGACGCCAAGACGCAGGGCCGCAATCGCATCCTGGCACATTCGCCCGAGGAGCGGCACTCCATGAAGGAC
GTCGGTTAG

Upstream 100 bases:

>100_bases
CCTGTTGTCGCGTTGCTGGCGACCAGCCTGGAGACGCAACTGCTGACGAATATAGGCTGACGGGTCTGCGATTTAACGAA
GCTCAAACCAGTATTGCCCT

Downstream 100 bases:

>100_bases
ATCGAATCCTTGATAGGTTTTTCCTATCGAGCCATCGCGCGTGCGCCCTTGATGTTTTCCCCGCTTCGACAATACAGGGC
GCATGGACACAAAATTCATT

Product: response regulator

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MIGSVHVLEGGSNAVNGIWTQFGGNLSFVCLAISLWAHFSIQFQSRSVTQEKIAFGIIAGGASIGSILLAVEVNPGIYID
IRFSPLALAGMFGGPIAAAFAASLAMVFRFAVGGTAMIDGLIAIAVATGIGLAANVWIRRRSAELMDVALLSLALGVALI
VLMAVLPTLVHARVLAIIGLPMTVLNCLATALCGFVLLKTQQWELERSILVTAFSQSPDYLYVKDRNSRFITVNENMSRL
FRFRTTAEMTGLSDFNLISRPRAEEFYYLEQQVMDTGVPLIDSVERIEDRYLLASKVPLKDRQGRVIGLAGVTRDVTERT
ALERELRKSKNLLSHAMAGMSDGIAMYDSKGFLVFCNDQYRTAFPLSGDARVVGAHISDILRRVAETGERTGIPDNDREE
WIKAASATLHSNKDEEVQLHNGDWRSIRTRLAEDGTAMAVVSDITATKQAEIALRLSAEQLRNLAETDGLTGIVNRRAFD
EAFARETAGSARKNTPFSLLMVDIDRFKAYNDTYGHPAGDQCLRVVSKCLRQSVSRPADIVARYGGEEFVVLLPATSAKG
AMIVAEQFARLLSQENIVHTGSEFGRVTASIGISCATGATLRLNPNRLLIEADAALYDAKTQGRNRILAHSPEERHSMKD
VG

Sequences:

>Translated_642_residues
MIGSVHVLEGGSNAVNGIWTQFGGNLSFVCLAISLWAHFSIQFQSRSVTQEKIAFGIIAGGASIGSILLAVEVNPGIYID
IRFSPLALAGMFGGPIAAAFAASLAMVFRFAVGGTAMIDGLIAIAVATGIGLAANVWIRRRSAELMDVALLSLALGVALI
VLMAVLPTLVHARVLAIIGLPMTVLNCLATALCGFVLLKTQQWELERSILVTAFSQSPDYLYVKDRNSRFITVNENMSRL
FRFRTTAEMTGLSDFNLISRPRAEEFYYLEQQVMDTGVPLIDSVERIEDRYLLASKVPLKDRQGRVIGLAGVTRDVTERT
ALERELRKSKNLLSHAMAGMSDGIAMYDSKGFLVFCNDQYRTAFPLSGDARVVGAHISDILRRVAETGERTGIPDNDREE
WIKAASATLHSNKDEEVQLHNGDWRSIRTRLAEDGTAMAVVSDITATKQAEIALRLSAEQLRNLAETDGLTGIVNRRAFD
EAFARETAGSARKNTPFSLLMVDIDRFKAYNDTYGHPAGDQCLRVVSKCLRQSVSRPADIVARYGGEEFVVLLPATSAKG
AMIVAEQFARLLSQENIVHTGSEFGRVTASIGISCATGATLRLNPNRLLIEADAALYDAKTQGRNRILAHSPEERHSMKD
VG
>Mature_642_residues
MIGSVHVLEGGSNAVNGIWTQFGGNLSFVCLAISLWAHFSIQFQSRSVTQEKIAFGIIAGGASIGSILLAVEVNPGIYID
IRFSPLALAGMFGGPIAAAFAASLAMVFRFAVGGTAMIDGLIAIAVATGIGLAANVWIRRRSAELMDVALLSLALGVALI
VLMAVLPTLVHARVLAIIGLPMTVLNCLATALCGFVLLKTQQWELERSILVTAFSQSPDYLYVKDRNSRFITVNENMSRL
FRFRTTAEMTGLSDFNLISRPRAEEFYYLEQQVMDTGVPLIDSVERIEDRYLLASKVPLKDRQGRVIGLAGVTRDVTERT
ALERELRKSKNLLSHAMAGMSDGIAMYDSKGFLVFCNDQYRTAFPLSGDARVVGAHISDILRRVAETGERTGIPDNDREE
WIKAASATLHSNKDEEVQLHNGDWRSIRTRLAEDGTAMAVVSDITATKQAEIALRLSAEQLRNLAETDGLTGIVNRRAFD
EAFARETAGSARKNTPFSLLMVDIDRFKAYNDTYGHPAGDQCLRVVSKCLRQSVSRPADIVARYGGEEFVVLLPATSAKG
AMIVAEQFARLLSQENIVHTGSEFGRVTASIGISCATGATLRLNPNRLLIEADAALYDAKTQGRNRILAHSPEERHSMKD
VG

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=217, Percent_Identity=35.9447004608295, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1787262, Length=180, Percent_Identity=39.4444444444444, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=38.75, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1786584, Length=194, Percent_Identity=37.1134020618557, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788381, Length=349, Percent_Identity=28.6532951289398, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=39.1566265060241, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=35.1515151515151, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787802, Length=170, Percent_Identity=31.7647058823529, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788085, Length=205, Percent_Identity=33.6585365853659, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787541, Length=202, Percent_Identity=32.1782178217822, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787056, Length=173, Percent_Identity=31.2138728323699, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 69874; Mature: 69874

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGSVHVLEGGSNAVNGIWTQFGGNLSFVCLAISLWAHFSIQFQSRSVTQEKIAFGIIAG
CCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHEEEEEEC
GASIGSILLAVEVNPGIYIDIRFSPLALAGMFGGPIAAAFAASLAMVFRFAVGGTAMIDG
CCCCCEEEEEEEECCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
LIAIAVATGIGLAANVWIRRRSAELMDVALLSLALGVALIVLMAVLPTLVHARVLAIIGL
HHHHHHHHCCCHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMTVLNCLATALCGFVLLKTQQWELERSILVTAFSQSPDYLYVKDRNSRFITVNENMSRL
HHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEEECCCCCEEEEEECCCEEEEECCCHHHH
FRFRTTAEMTGLSDFNLISRPRAEEFYYLEQQVMDTGVPLIDSVERIEDRYLLASKVPLK
HHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCC
DRQGRVIGLAGVTRDVTERTALERELRKSKNLLSHAMAGMSDGIAMYDSKGFLVFCNDQY
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCC
RTAFPLSGDARVVGAHISDILRRVAETGERTGIPDNDREEWIKAASATLHSNKDEEVQLH
CEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
NGDWRSIRTRLAEDGTAMAVVSDITATKQAEIALRLSAEQLRNLAETDGLTGIVNRRAFD
CCCHHHHHHHHHCCCCEEEEEHHHHHCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHH
EAFARETAGSARKNTPFSLLMVDIDRFKAYNDTYGHPAGDQCLRVVSKCLRQSVSRPADI
HHHHHHHCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VARYGGEEFVVLLPATSAKGAMIVAEQFARLLSQENIVHTGSEFGRVTASIGISCATGAT
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCHHHHEEHHHCCEEEECCCE
LRLNPNRLLIEADAALYDAKTQGRNRILAHSPEERHSMKDVG
EEECCCEEEEEECCHHCCCCCCCCCCEECCCCHHHHCCCCCC
>Mature Secondary Structure
MIGSVHVLEGGSNAVNGIWTQFGGNLSFVCLAISLWAHFSIQFQSRSVTQEKIAFGIIAG
CCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHEEEEEEC
GASIGSILLAVEVNPGIYIDIRFSPLALAGMFGGPIAAAFAASLAMVFRFAVGGTAMIDG
CCCCCEEEEEEEECCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
LIAIAVATGIGLAANVWIRRRSAELMDVALLSLALGVALIVLMAVLPTLVHARVLAIIGL
HHHHHHHHCCCHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMTVLNCLATALCGFVLLKTQQWELERSILVTAFSQSPDYLYVKDRNSRFITVNENMSRL
HHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEEECCCCCEEEEEECCCEEEEECCCHHHH
FRFRTTAEMTGLSDFNLISRPRAEEFYYLEQQVMDTGVPLIDSVERIEDRYLLASKVPLK
HHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCC
DRQGRVIGLAGVTRDVTERTALERELRKSKNLLSHAMAGMSDGIAMYDSKGFLVFCNDQY
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCC
RTAFPLSGDARVVGAHISDILRRVAETGERTGIPDNDREEWIKAASATLHSNKDEEVQLH
CEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEE
NGDWRSIRTRLAEDGTAMAVVSDITATKQAEIALRLSAEQLRNLAETDGLTGIVNRRAFD
CCCHHHHHHHHHCCCCEEEEEHHHHHCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHH
EAFARETAGSARKNTPFSLLMVDIDRFKAYNDTYGHPAGDQCLRVVSKCLRQSVSRPADI
HHHHHHHCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHH
VARYGGEEFVVLLPATSAKGAMIVAEQFARLLSQENIVHTGSEFGRVTASIGISCATGAT
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCHHHHEEHHHCCEEEECCCE
LRLNPNRLLIEADAALYDAKTQGRNRILAHSPEERHSMKDVG
EEECCCEEEEEECCHHCCCCCCCCCCEECCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]