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The map label for this gene is gsiC [H]

Identifier: 116249099

GI number: 116249099

Start: 465992

End: 466945

Strand: Reverse

Name: gsiC [H]

Synonym: pRL120433

Alternate gene names: 116249099

Gene position: 466945-465992 (Counterclockwise)

Preceding gene: 116249100

Following gene: 116249098

Centisome position: 53.67

GC content: 61.43

Gene sequence:

>954_bases
ATGCTGGCCTATGCCTTGAAACGACTGCTGCATGTCATTCCCGTGGCCATCGGTGTGAGCATCGTTTGCTTCATGCTGAT
CCATATAGCTCCAGGTGACCCACTGGCCGCGATCCTGCCATCCGACGCCTCTGCAGAGATGCAGAACCAGATGCGGGCCT
TCTACGGCCTTGATCGCCCGCTGCCGGTGCAATATGCCCTGTGGGCATGGCGTACGCTGCATGGCGACCTGGGTGTCTCG
ATCGCGTCCGGCCGCCCGGTGCTCAGCGAAATCATGGATGCCTCGGTCAACTCGATCATCCTGGCGCTTGCCGCGACGAT
CATCGGCTTCACCGTCGGCTCGGTACTCGGCTTCGTGGCAGGCGTCTTCCGGGGCGGCTGGATCGATCGCCTCGCCTCCG
CTTTCGCGATGCTTGGTGTCAGCGTCCCGCATTACTGGCTGGGCATGGTTCTCGTCATTGCATTTTCTGTCACGCTCGGT
TGGCTGCCGGCAATGGGCGGCGGGCCTGGAGGATCGGACGGACGCAGCTTCAGCTGGGAATATATGCAATACCTGATCCT
ACCTGCGGTCACGATGTCCGTCATCCCGATGGGAATAATCGCCCGCACCATCCGCTCGCTGGTGGCCGATATCCTGTCAC
AGGATTTCACCCAGGCGCTGGCTGCCAAGGGGCTGATGAACCGGCAGATCATGCGCCATGTGGTGCGCAATGCCGCCCCG
ACCGCAATTTCTGTCATGGGCCTGCAGCTCGGCTATCTCCTGGGCGGATCGATCCTGATCGAGACCGTGTTCTCCTGGCC
GGGCACCGGCTTCCTGTTGAACGGCGCCATCTTCACCCGCGACCTGCCGATCCTGCAGGGCACGATCCTCGTACTTGCGA
TGTTCTTCGTCCTCCTGAACCTCATCGTCGATGTGCTGCAGAGCGCAATCGATCCACGCATCCAGAGGAGCTGA

Upstream 100 bases:

>100_bases
CACCATCAGCATGGACCCCTGATCCAACGCATGGGCCTGCGCGCCGGCACGCCGGCGCGCAGTTCATTATGCCCGATCCG
AACAATATTGTGAGGAAACC

Downstream 100 bases:

>100_bases
CCCATGGCCGTCATTACAGCAGATCTGGCCTCGGAAGCGCCCAAAATCCTCAAATCACCGGGTTTCTGGAGCGGTGTCGT
TCGCCGTCTTTGTCGTGATC

Product: putative permease component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MLAYALKRLLHVIPVAIGVSIVCFMLIHIAPGDPLAAILPSDASAEMQNQMRAFYGLDRPLPVQYALWAWRTLHGDLGVS
IASGRPVLSEIMDASVNSIILALAATIIGFTVGSVLGFVAGVFRGGWIDRLASAFAMLGVSVPHYWLGMVLVIAFSVTLG
WLPAMGGGPGGSDGRSFSWEYMQYLILPAVTMSVIPMGIIARTIRSLVADILSQDFTQALAAKGLMNRQIMRHVVRNAAP
TAISVMGLQLGYLLGGSILIETVFSWPGTGFLLNGAIFTRDLPILQGTILVLAMFFVLLNLIVDVLQSAIDPRIQRS

Sequences:

>Translated_317_residues
MLAYALKRLLHVIPVAIGVSIVCFMLIHIAPGDPLAAILPSDASAEMQNQMRAFYGLDRPLPVQYALWAWRTLHGDLGVS
IASGRPVLSEIMDASVNSIILALAATIIGFTVGSVLGFVAGVFRGGWIDRLASAFAMLGVSVPHYWLGMVLVIAFSVTLG
WLPAMGGGPGGSDGRSFSWEYMQYLILPAVTMSVIPMGIIARTIRSLVADILSQDFTQALAAKGLMNRQIMRHVVRNAAP
TAISVMGLQLGYLLGGSILIETVFSWPGTGFLLNGAIFTRDLPILQGTILVLAMFFVLLNLIVDVLQSAIDPRIQRS
>Mature_317_residues
MLAYALKRLLHVIPVAIGVSIVCFMLIHIAPGDPLAAILPSDASAEMQNQMRAFYGLDRPLPVQYALWAWRTLHGDLGVS
IASGRPVLSEIMDASVNSIILALAATIIGFTVGSVLGFVAGVFRGGWIDRLASAFAMLGVSVPHYWLGMVLVIAFSVTLG
WLPAMGGGPGGSDGRSFSWEYMQYLILPAVTMSVIPMGIIARTIRSLVADILSQDFTQALAAKGLMNRQIMRHVVRNAAP
TAISVMGLQLGYLLGGSILIETVFSWPGTGFLLNGAIFTRDLPILQGTILVLAMFFVLLNLIVDVLQSAIDPRIQRS

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=38.9240506329114, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1789888, Length=324, Percent_Identity=38.8888888888889, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=36.1764705882353, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1787761, Length=331, Percent_Identity=35.9516616314199, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787497, Length=319, Percent_Identity=30.0940438871473, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=32.089552238806, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788504, Length=362, Percent_Identity=26.5193370165746, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34020; Mature: 34020

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAYALKRLLHVIPVAIGVSIVCFMLIHIAPGDPLAAILPSDASAEMQNQMRAFYGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCC
LPVQYALWAWRTLHGDLGVSIASGRPVLSEIMDASVNSIILALAATIIGFTVGSVLGFVA
CCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVFRGGWIDRLASAFAMLGVSVPHYWLGMVLVIAFSVTLGWLPAMGGGPGGSDGRSFSWE
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
YMQYLILPAVTMSVIPMGIIARTIRSLVADILSQDFTQALAAKGLMNRQIMRHVVRNAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TAISVMGLQLGYLLGGSILIETVFSWPGTGFLLNGAIFTRDLPILQGTILVLAMFFVLLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHH
LIVDVLQSAIDPRIQRS
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLAYALKRLLHVIPVAIGVSIVCFMLIHIAPGDPLAAILPSDASAEMQNQMRAFYGLDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCC
LPVQYALWAWRTLHGDLGVSIASGRPVLSEIMDASVNSIILALAATIIGFTVGSVLGFVA
CCHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVFRGGWIDRLASAFAMLGVSVPHYWLGMVLVIAFSVTLGWLPAMGGGPGGSDGRSFSWE
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
YMQYLILPAVTMSVIPMGIIARTIRSLVADILSQDFTQALAAKGLMNRQIMRHVVRNAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TAISVMGLQLGYLLGGSILIETVFSWPGTGFLLNGAIFTRDLPILQGTILVLAMFFVLLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHH
LIVDVLQSAIDPRIQRS
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA