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The map label for this gene is hyuE [H]

Identifier: 116249095

GI number: 116249095

Start: 462328

End: 463008

Strand: Reverse

Name: hyuE [H]

Synonym: pRL120429

Alternate gene names: 116249095

Gene position: 463008-462328 (Counterclockwise)

Preceding gene: 116249096

Following gene: 116249094

Centisome position: 53.22

GC content: 60.35

Gene sequence:

>681_bases
ATGACACACATCGTTATCATCAATCCAAACACATCGGAGGCGACCACGGCGATGATGACCGACATCGCTCGCCAGTCTGT
TCCCGCTGGCATTTCGGTCGAAGGCGTGACCGCGGCAAGAGGCGTGCCGATGATCCTCAACGGCAATGAGCTTGCCGCCT
CCGCCGACGGCGTCGTGCAGATGGGGTTGACCGCGGCGTCAAGGGCTGATGGCATCATCGTCAGCGCTTTCGGGGATCCG
GGGCTCGAACCGCTGAGACAAATGACCGATATACCCATTATCGGCATATGCGAGGCAAGCATGCTGGAAGCTGCGTTCGG
CGGACGACGGTTCGGCATTGCGACAGTCACACCAGATCTCGTCGAGAGCTTCGCGGCAAAGGCAGTGAGCCTCGGGCTTG
CCAACCTTTTCACCGGCACTCGATTGACCAGTGGGGACCCAATCTCTCTCTCCTTCGAGCCAGAGCGGCTGCAGACAGCC
CTCGCCATTGCCGTCAAAGAGTGCCTGGATTTTGATGGCGCCGAGGTGGTCATCATCGGCGGCGGGCCGCTTGGCAGAGC
AGCGGCCCAACTTCAGCAGCAGCTGTCCGCGCCAGTGATCGCCCCGATTGAATCAGCCACTAAACTCCTCCTCAAGCGGA
TGTTTCCTCTCGCATCAGTCGCTGCGAGTTTGGCGCAGTGA

Upstream 100 bases:

>100_bases
GGACGAGCTGGCCGGGTTGCCTGCCTTCTATACGGCTGAGAAACCCGAAAAATACAATAAATCAGGGAGGTGGACGCGCG
GCTGCGGCGTCCGAAGGACC

Downstream 100 bases:

>100_bases
CAAGGGCGCTCGGGCGCGGCAGCTTGAGTTTTCCGATTGCAAATCGGGAGATTGCGACGGAAAGTCCGCCGCCTGGAGAT
GTCGCGGAGAGTACTGTGCC

Product: putative hydantoin racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTHIVIINPNTSEATTAMMTDIARQSVPAGISVEGVTAARGVPMILNGNELAASADGVVQMGLTAASRADGIIVSAFGDP
GLEPLRQMTDIPIIGICEASMLEAAFGGRRFGIATVTPDLVESFAAKAVSLGLANLFTGTRLTSGDPISLSFEPERLQTA
LAIAVKECLDFDGAEVVIIGGGPLGRAAAQLQQQLSAPVIAPIESATKLLLKRMFPLASVAASLAQ

Sequences:

>Translated_226_residues
MTHIVIINPNTSEATTAMMTDIARQSVPAGISVEGVTAARGVPMILNGNELAASADGVVQMGLTAASRADGIIVSAFGDP
GLEPLRQMTDIPIIGICEASMLEAAFGGRRFGIATVTPDLVESFAAKAVSLGLANLFTGTRLTSGDPISLSFEPERLQTA
LAIAVKECLDFDGAEVVIIGGGPLGRAAAQLQQQLSAPVIAPIESATKLLLKRMFPLASVAASLAQ
>Mature_225_residues
THIVIINPNTSEATTAMMTDIARQSVPAGISVEGVTAARGVPMILNGNELAASADGVVQMGLTAASRADGIIVSAFGDPG
LEPLRQMTDIPIIGICEASMLEAAFGGRRFGIATVTPDLVESFAAKAVSLGLANLFTGTRLTSGDPISLSFEPERLQTAL
AIAVKECLDFDGAEVVIIGGGPLGRAAAQLQQQLSAPVIAPIESATKLLLKRMFPLASVAASLAQ

Specific function: Responsible for racemization of the D-5-substituted hydantoins to their corresponding L-amino acids [H]

COG id: COG4126

COG function: function code E; Hydantoin racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To yeast DCG1 and S.pombe SPAC1F7.10 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.99.5 [H]

Molecular weight: Translated: 23169; Mature: 23038

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIVIINPNTSEATTAMMTDIARQSVPAGISVEGVTAARGVPMILNGNELAASADGVVQ
CEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHCCCEEEECCCCCCCCCCCCEE
MGLTAASRADGIIVSAFGDPGLEPLRQMTDIPIIGICEASMLEAAFGGRRFGIATVTPDL
ECCHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEECHHHHHHHHHCCCEEEEEECCHHH
VESFAAKAVSLGLANLFTGTRLTSGDPISLSFEPERLQTALAIAVKECLDFDGAEVVIIG
HHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEC
GGPLGRAAAQLQQQLSAPVIAPIESATKLLLKRMFPLASVAASLAQ
CCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THIVIINPNTSEATTAMMTDIARQSVPAGISVEGVTAARGVPMILNGNELAASADGVVQ
EEEEEECCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHCCCEEEECCCCCCCCCCCCEE
MGLTAASRADGIIVSAFGDPGLEPLRQMTDIPIIGICEASMLEAAFGGRRFGIATVTPDL
ECCHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEECHHHHHHHHHCCCEEEEEECCHHH
VESFAAKAVSLGLANLFTGTRLTSGDPISLSFEPERLQTALAIAVKECLDFDGAEVVIIG
HHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEC
GGPLGRAAAQLQQQLSAPVIAPIESATKLLLKRMFPLASVAASLAQ
CCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339422 [H]