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The map label for this gene is dctM [H]

Identifier: 116249068

GI number: 116249068

Start: 434296

End: 435702

Strand: Direct

Name: dctM [H]

Synonym: pRL120402

Alternate gene names: 116249068

Gene position: 434296-435702 (Clockwise)

Preceding gene: 116249067

Following gene: 116249069

Centisome position: 49.92

GC content: 61.41

Gene sequence:

>1407_bases
ATGCTGCTGCTTCTAGGTTCGTTCCTGGTGTTGATGCTGATCGGGGTGCCCGTCGCCATTTCGATGGCCGTCGCATCCGT
GCTCTACATCGTCCTTTATGGCGTCGCGCCGGACATTATCGTCGCCCAGCGCATGATCGCCGGCGTCGAAAGCTTCCCGC
TGCTCGCCGTGCCGTTCTTCATCCTCGCGGGCAACCTGATGAACTCGGCCGGTGTCACCGGCCGCATCTATTCCTTTGCC
GTTGCTCTCGTCGGCTGGATGAAGGGCGGTCTCGCGCAGGTCAACATCATCGGTTCGGTGATCTTCTCCGGCATGTCGGG
CACCGCGCTTGCCGATGCCGCGGGTATCGGCACGATCGAGATCAAGGCGATGAAGGATCACGGCTATCCGGTCGAGGCCG
CGGTCGGCGTGACGGCGGCCTCGGCAACGCTCGGCCCGATCTTCCCGCCATCGCTGCCTTTCGTGATCTACGGCATGATG
GCGAACGTCTCGATCGGCGCTCTTTTCATGGCGGGCATCCTGCCCGGCATCGTCATGACGCTGTTGATGATGATCACGGT
CGCCGCCTTTGCTTATAAGAAGCGGTGGGGCTCGGATGCGCCGTTTAATGTCAGAGAGCTCCTATCGGCGGGGATGGAAA
TCGTCGTCGTCCTGGCGGTGCCGCTGGCCATCTATCTGATGATGCGGGCCGGCGTATCGATGAATGTTGCGGCGGGCATT
GCTCTTGCCCTCCTTCTAGCCCTCGACTGGTATTTCCGCTTCTCCGCCGTCATGGCGCTGATGACGCCCGTCATCCTGAT
CGGCGGCATGACGATGGGCTGGTTCACGCCGACGGAGGCAGCCGTCGCAGCCGTCCTCTGGTCTCTGTTCCTCGGTCTGG
TGCGTTACCGCACGATGACGCCCTCGACGCTCGCCAAGGCAAGCTTCGATACGATCGAGACGACGGCATCCGTTCTCTTC
ATCGTCACCGCGGCATCGGTCTTCGCATGGCTGCTGACGGTAAGCCAGGCGGCCCAGCTGCTGTCCGATGCAATCCTGTC
GATCACCGACAATAAATGGGTTTTCCTGATCCTCGTGAACCTGCTGATGCTCTTCGTCGGCTGCTTCCTGGACACGATCG
CGGCCATCACCATCCTCGTGCCGATCCTTCTGCCGATCGTCCTGAAATTCGGGATCGATCCCGTCCAGTTCGGCCTCATC
ATGACGCTGAACCTGATGATCGGTCTGTTGCACCCGCCGCTCGGCATGGTGCTTTTCGTGCTGTCGAGGGTCGCGAAACT
TTCTGTCGAACGCACGACCATGGCGATCCTGCCCTGGCTGGTGCCGCTCTTCCTGGCGCTGATCCTGATCACCTTCGTGC
CCGCCATATCGCTGTGGCTGCCGCAGCAACTCGGGCTGCTGAGATAG

Upstream 100 bases:

>100_bases
ATGCTGATCCGCGCGGTCATCGTCTTCATCGCCAACATGCGCCGCGGCTACTCCGTTCTGGAGCGCCCCGAAGAATTCCA
GACCGTCGAGGGTTGATCAG

Downstream 100 bases:

>100_bases
GAGTGGAAGATGCGGACACGTGTGGCACGGCTTTACCAAAAGGGCGACCTCAGGATCGAGACCGCCGCGGTTGCGGCCCC
TGGTCCCGGGGAGGTGCTTC

Product: putative large transmembrane TRAP C4-dicarboxylate membrane transport protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MLLLLGSFLVLMLIGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFFILAGNLMNSAGVTGRIYSFA
VALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIEIKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMM
ANVSIGALFMAGILPGIVMTLLMMITVAAFAYKKRWGSDAPFNVRELLSAGMEIVVVLAVPLAIYLMMRAGVSMNVAAGI
ALALLLALDWYFRFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMTPSTLAKASFDTIETTASVLF
IVTAASVFAWLLTVSQAAQLLSDAILSITDNKWVFLILVNLLMLFVGCFLDTIAAITILVPILLPIVLKFGIDPVQFGLI
MTLNLMIGLLHPPLGMVLFVLSRVAKLSVERTTMAILPWLVPLFLALILITFVPAISLWLPQQLGLLR

Sequences:

>Translated_468_residues
MLLLLGSFLVLMLIGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFFILAGNLMNSAGVTGRIYSFA
VALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIEIKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMM
ANVSIGALFMAGILPGIVMTLLMMITVAAFAYKKRWGSDAPFNVRELLSAGMEIVVVLAVPLAIYLMMRAGVSMNVAAGI
ALALLLALDWYFRFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMTPSTLAKASFDTIETTASVLF
IVTAASVFAWLLTVSQAAQLLSDAILSITDNKWVFLILVNLLMLFVGCFLDTIAAITILVPILLPIVLKFGIDPVQFGLI
MTLNLMIGLLHPPLGMVLFVLSRVAKLSVERTTMAILPWLVPLFLALILITFVPAISLWLPQQLGLLR
>Mature_468_residues
MLLLLGSFLVLMLIGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFFILAGNLMNSAGVTGRIYSFA
VALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIEIKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMM
ANVSIGALFMAGILPGIVMTLLMMITVAAFAYKKRWGSDAPFNVRELLSAGMEIVVVLAVPLAIYLMMRAGVSMNVAAGI
ALALLLALDWYFRFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMTPSTLAKASFDTIETTASVLF
IVTAASVFAWLLTVSQAAQLLSDAILSITDNKWVFLILVNLLMLFVGCFLDTIAAITILVPILLPIVLKFGIDPVQFGLI
MTLNLMIGLLHPPLGMVLFVLSRVAKLSVERTTMAILPWLVPLFLALILITFVPAISLWLPQQLGLLR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=456, Percent_Identity=33.9912280701754, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 49775; Mature: 49775

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLLGSFLVLMLIGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHCCHHHHHHHH
ILAGNLMNSAGVTGRIYSFAVALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEE
IKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMMANVSIGALFMAGILPGIVMT
EEEECCCCCCCHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMMITVAAFAYKKRWGSDAPFNVRELLSAGMEIVVVLAVPLAIYLMMRAGVSMNVAAGI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ALALLLALDWYFRFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PSTLAKASFDTIETTASVLFIVTAASVFAWLLTVSQAAQLLSDAILSITDNKWVFLILVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLMLFVGCFLDTIAAITILVPILLPIVLKFGIDPVQFGLIMTLNLMIGLLHPPLGMVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LSRVAKLSVERTTMAILPWLVPLFLALILITFVPAISLWLPQQLGLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLLLGSFLVLMLIGVPVAISMAVASVLYIVLYGVAPDIIVAQRMIAGVESFPLLAVPFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHCCHHHHHHHH
ILAGNLMNSAGVTGRIYSFAVALVGWMKGGLAQVNIIGSVIFSGMSGTALADAAGIGTIE
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCEEE
IKAMKDHGYPVEAAVGVTAASATLGPIFPPSLPFVIYGMMANVSIGALFMAGILPGIVMT
EEEECCCCCCCHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMMITVAAFAYKKRWGSDAPFNVRELLSAGMEIVVVLAVPLAIYLMMRAGVSMNVAAGI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ALALLLALDWYFRFSAVMALMTPVILIGGMTMGWFTPTEAAVAAVLWSLFLGLVRYRTMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PSTLAKASFDTIETTASVLFIVTAASVFAWLLTVSQAAQLLSDAILSITDNKWVFLILVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLMLFVGCFLDTIAAITILVPILLPIVLKFGIDPVQFGLIMTLNLMIGLLHPPLGMVLFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
LSRVAKLSVERTTMAILPWLVPLFLALILITFVPAISLWLPQQLGLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]