Click here to switch to the map view.

The map label for this gene is 116248966

Identifier: 116248966

GI number: 116248966

Start: 314299

End: 315636

Strand: Direct

Name: 116248966

Synonym: pRL120297

Alternate gene names: NA

Gene position: 314299-315636 (Clockwise)

Preceding gene: 116248965

Following gene: 116248972

Centisome position: 36.13

GC content: 59.79

Gene sequence:

>1338_bases
ATGAAGAAGTTTGACAATATTCTCGCCTGGCGCCGGCTTGCCCGCGGAGCAATGGTGATGGCGGTTGGACCGATGTTGCT
GTTCCCAGCCGGTTACCTTGTGCCAGCGAGTGCCGCCGACGTCACATCGGACGGGCCGGCGACGCCGATCGAGGCCGACG
AAACGATCCGCCCGTTCCAGATCCACGTTCCGCAGTCACAGCTTGACGATCTGCGCAAGCGCATTGCCGAAGCGCGTTGG
CCAGATAAGGAAACCGTGAGCGACACCTCGCAAGGCATCCAGCTTTCGCGCGTCCAGGATCTGGTCCGTTACTGGGGCAC
TGATTACGATTGGCGCAAAGCCGAGGCGGAGCTCAATGCACTTCCGGAATTCATCACGACGATCGACGGGGTCGATATCC
AGTTCATCCATGTGCGATCGCGTCATCCCAACGCCCTTCCGGTCATTCTGACCCATGGTTGGCCGGGTTCGACCTTCGAG
TTCATCAAGGCGATCGGCCCTCTTACCGATCCGACTGCTTATGGCGGTAAAGCGGAGGACGCATTTGACGTGGTCATTCC
TTCCATCCCCGGCTACGGCTTTTCGGGTAAGCCGACGGAGCTTGGCTGGGGCCCCGACCGCGTTGCGCGGGCATGGGACA
TCCTGATGAAGCGGCTCGGCTATGCGCACTACGTTTCCCAGGGTGGCGACCATGGTTCCGTTATCTCCGACGCGCTGGCG
CGCCAGGCACCGAAGGGCCTGCTTGGTATCCATCTCAACATGCCGGCGACCGTTCCGGGCAATCTCACCAAGGCGATCAA
CAGTGGAGACCCGGCTCCTGCGGGACTGTCGGCGCTCGAGCGGGATGCCTATGAATCGTTGAGCACCTTCTTCGGCCGGA
ATGCGGCCTACGGGGCCGTGATGGTGACGCGTCCGCAGACGATCGGCTACTCGCTTTCCGACTCACCGTCGGGACTGGCT
GCCTGGATCTACGAAAAATTTGCTCAATGGAGCGACAGCGAGGGCATTCCCGAGCGCGTTTTTTCCAAGGACGAAATGCT
GAATGACATCACATTGTACTGGCTGACCAACACGGGGGCATCCTCGTCGCGGTTCTATTGGGAGAACAACAACAACAACT
TCAGCTCAGACGCGCAGAAGACCAAAGAGATCAAGATCCCGGTGGCAATCAGCGTATTCCCAAAGGAGATCTACCAGGCG
CCGGAGAGTTGGAGCAAGGAGGCCTACCCCACGCTGCATTACTACCACCGTGTCGATATGGGCGGTCACTTCGCCGCCTG
GGAACAGCCCCAGCTTTTCGCTGAGGAACTGCGAGAGGCATTCAGGTCGGTGCGTTGA

Upstream 100 bases:

>100_bases
ACGTTTTTGGCATTTCCTGAAACATGCCAGATACGCAGACCCGTCAGACATCACTCCGTCACGAAATGTCGCCTCGGGCG
ACAAGAACATGGAGTGCCTC

Downstream 100 bases:

>100_bases
TACATCGGCTGCAGAATGACGGCTTGGCATATCCGCGGCTGAGAGTGGCGAATTCAAAGCCGCGGAGAATCCAGCTCGAA
CCGTTTCATCAAATCTTCCT

Product: putative epoxide hydrolase

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKKFDNILAWRRLARGAMVMAVGPMLLFPAGYLVPASAADVTSDGPATPIEADETIRPFQIHVPQSQLDDLRKRIAEARW
PDKETVSDTSQGIQLSRVQDLVRYWGTDYDWRKAEAELNALPEFITTIDGVDIQFIHVRSRHPNALPVILTHGWPGSTFE
FIKAIGPLTDPTAYGGKAEDAFDVVIPSIPGYGFSGKPTELGWGPDRVARAWDILMKRLGYAHYVSQGGDHGSVISDALA
RQAPKGLLGIHLNMPATVPGNLTKAINSGDPAPAGLSALERDAYESLSTFFGRNAAYGAVMVTRPQTIGYSLSDSPSGLA
AWIYEKFAQWSDSEGIPERVFSKDEMLNDITLYWLTNTGASSSRFYWENNNNNFSSDAQKTKEIKIPVAISVFPKEIYQA
PESWSKEAYPTLHYYHRVDMGGHFAAWEQPQLFAEELREAFRSVR

Sequences:

>Translated_445_residues
MKKFDNILAWRRLARGAMVMAVGPMLLFPAGYLVPASAADVTSDGPATPIEADETIRPFQIHVPQSQLDDLRKRIAEARW
PDKETVSDTSQGIQLSRVQDLVRYWGTDYDWRKAEAELNALPEFITTIDGVDIQFIHVRSRHPNALPVILTHGWPGSTFE
FIKAIGPLTDPTAYGGKAEDAFDVVIPSIPGYGFSGKPTELGWGPDRVARAWDILMKRLGYAHYVSQGGDHGSVISDALA
RQAPKGLLGIHLNMPATVPGNLTKAINSGDPAPAGLSALERDAYESLSTFFGRNAAYGAVMVTRPQTIGYSLSDSPSGLA
AWIYEKFAQWSDSEGIPERVFSKDEMLNDITLYWLTNTGASSSRFYWENNNNNFSSDAQKTKEIKIPVAISVFPKEIYQA
PESWSKEAYPTLHYYHRVDMGGHFAAWEQPQLFAEELREAFRSVR
>Mature_445_residues
MKKFDNILAWRRLARGAMVMAVGPMLLFPAGYLVPASAADVTSDGPATPIEADETIRPFQIHVPQSQLDDLRKRIAEARW
PDKETVSDTSQGIQLSRVQDLVRYWGTDYDWRKAEAELNALPEFITTIDGVDIQFIHVRSRHPNALPVILTHGWPGSTFE
FIKAIGPLTDPTAYGGKAEDAFDVVIPSIPGYGFSGKPTELGWGPDRVARAWDILMKRLGYAHYVSQGGDHGSVISDALA
RQAPKGLLGIHLNMPATVPGNLTKAINSGDPAPAGLSALERDAYESLSTFFGRNAAYGAVMVTRPQTIGYSLSDSPSGLA
AWIYEKFAQWSDSEGIPERVFSKDEMLNDITLYWLTNTGASSSRFYWENNNNNFSSDAQKTKEIKIPVAISVFPKEIYQA
PESWSKEAYPTLHYYHRVDMGGHFAAWEQPQLFAEELREAFRSVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=418, Percent_Identity=37.5598086124402, Blast_Score=281, Evalue=7e-76,
Organism=Homo sapiens, GI209862837, Length=418, Percent_Identity=37.5598086124402, Blast_Score=281, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17564944, Length=430, Percent_Identity=35.8139534883721, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI193207462, Length=414, Percent_Identity=27.2946859903382, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24655327, Length=457, Percent_Identity=30.6345733041575, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI20130139, Length=413, Percent_Identity=30.9927360774818, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19922580, Length=413, Percent_Identity=29.7820823244552, Blast_Score=175, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 49402; Mature: 49402

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFDNILAWRRLARGAMVMAVGPMLLFPAGYLVPASAADVTSDGPATPIEADETIRPFQ
CCHHHHHHHHHHHHCCCEEEHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
IHVPQSQLDDLRKRIAEARWPDKETVSDTSQGIQLSRVQDLVRYWGTDYDWRKAEAELNA
EECCHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEHHHHHHHHHHHCCCCCHHHHHHHHHH
LPEFITTIDGVDIQFIHVRSRHPNALPVILTHGWPGSTFEFIKAIGPLTDPTAYGGKAED
HHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCC
AFDVVIPSIPGYGFSGKPTELGWGPDRVARAWDILMKRLGYAHYVSQGGDHGSVISDALA
CCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHH
RQAPKGLLGIHLNMPATVPGNLTKAINSGDPAPAGLSALERDAYESLSTFFGRNAAYGAV
HHCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
MVTRPQTIGYSLSDSPSGLAAWIYEKFAQWSDSEGIPERVFSKDEMLNDITLYWLTNTGA
EEECCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHCCEEEEEEECCCC
SSSRFYWENNNNNFSSDAQKTKEIKIPVAISVFPKEIYQAPESWSKEAYPTLHYYHRVDM
CCCEEEEECCCCCCCCHHHHHHEEEEEEEEEECHHHHHHCCHHCCCCCCCCEEEEEEECC
GGHFAAWEQPQLFAEELREAFRSVR
CCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKFDNILAWRRLARGAMVMAVGPMLLFPAGYLVPASAADVTSDGPATPIEADETIRPFQ
CCHHHHHHHHHHHHCCCEEEHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
IHVPQSQLDDLRKRIAEARWPDKETVSDTSQGIQLSRVQDLVRYWGTDYDWRKAEAELNA
EECCHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEHHHHHHHHHHHCCCCCHHHHHHHHHH
LPEFITTIDGVDIQFIHVRSRHPNALPVILTHGWPGSTFEFIKAIGPLTDPTAYGGKAED
HHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCC
AFDVVIPSIPGYGFSGKPTELGWGPDRVARAWDILMKRLGYAHYVSQGGDHGSVISDALA
CCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHH
RQAPKGLLGIHLNMPATVPGNLTKAINSGDPAPAGLSALERDAYESLSTFFGRNAAYGAV
HHCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEE
MVTRPQTIGYSLSDSPSGLAAWIYEKFAQWSDSEGIPERVFSKDEMLNDITLYWLTNTGA
EEECCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHCCEEEEEEECCCC
SSSRFYWENNNNNFSSDAQKTKEIKIPVAISVFPKEIYQAPESWSKEAYPTLHYYHRVDM
CCCEEEEECCCCCCCCHHHHHHEEEEEEEEEECHHHHHHCCHHCCCCCCCCEEEEEEECC
GGHFAAWEQPQLFAEELREAFRSVR
CCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]