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The map label for this gene is aldH [H]

Identifier: 116248905

GI number: 116248905

Start: 244958

End: 246475

Strand: Reverse

Name: aldH [H]

Synonym: pRL120235

Alternate gene names: 116248905

Gene position: 246475-244958 (Counterclockwise)

Preceding gene: 116248906

Following gene: 116248904

Centisome position: 28.33

GC content: 65.61

Gene sequence:

>1518_bases
ATGAGCTGGACCCCTTCAGGCAAGCATTTCATCGCCGGCGAATGGATTGCCGGAACGACGACATTTCAGTCCGAGCCGGC
GCATGGGCAGGCACACGACTTTGCTGTCGGCACAACGGAACTGGTCGACCGCGCCTGCCGCGCTGCCGAAGCTGCTTTTG
CAGCATTTTCGGCAACGACACGCGAGGAGCGCGCCATTTTCCTCGAGGCAATCGCCGAGGAGATCGACAAGCGCGGCGAG
GCCGTCACCCTCATCGGAACGCAGGAAACCGGGCTTCCGGAGGGCCGGCTCAACGGCGAACGTGCTCGTACCACCGGCCA
ACTCAGGCTGTTTGCCGACCATATCCGCAAGGGCGCGCATCTCGACGCCAGCGTCGATGCGGCGCAACCGGACCGGCAAC
CGGCGCCGCGGCCCGAGATCCGTCTGGTGCAACGGCCGATCGGCCCGGTCGCCGTCTTCGGCGCCTCGAATTTTCCGCTG
GCATTCTCGACCGCCGGCGGCGATACGGCAGCCGCGCTTGCCGCCGGTTGCCCGGTCGTGGTGAAGGGACATTCAGCCCA
TCCCGGCACAGGTGAGATCATCGCCGAGGCGATTGCAGCCGCTATCGAGCGCACTGGAATGCCGGCCGGCGTCTTCAGCC
TGATCCAGGGCGGTCGCCGTGATGTCGGAACGGCGCTGGTGACCCATCCGGCCATCAAAGCCGTTGGCTTTACCGGCTCG
CTTGCCGGCGGTCGGGCGCTCTTTGACCTTTGCGCCCAGCGCCCTGAGCCGATCCCCTTTTTCGGGGAACTCGGCAGCGT
TAATCCGATGTTCCTGCTGCCGGCCGCTACCGCTGCCCGGGCGGAGGCAATCGGTTCCGGCTGGGCCGGGTCACTGACGC
TTGGTGCCGGCCAGTTCTGCACCAAGCCCGGTATCGCCGTCGTCGTCGACGGGCCGGAGGCGGACAAGTTCACCAGTGCC
GCCAAGGCGGCTCTTGAAAAGGTGGCGCCGCAGACGATGCTGACCAAAGGTATCGCCACGGCCTATCACGACGGTGCCGA
CCGCCTGCGGGCGAGCAATGCCGTCGCGCCGGTTCTTGCTGCAAAGAGTGCTGACCGCGACGCAGCGCCGAACCTGTTCG
AGACCAACGGCTCGGCCTGGCTTGCCGATCACTCCCTCAGCGAAGAGGTGTTCGGCCCTCTCGGCCTCGTCGTGCGCGTC
GACTCGCCTGAAAAGATGCTCGCCCTTGCCGAAAGCTTCCAGGGACAGCTGACCGCGACGATCCATATGGACGACGCCGA
TCTTGGCCTTGCCCGCGACCTGCTGCCGATCCTCGAAAGGAAGGCTGGCAGATTGCTGGTCAATGGCTTCCCAACCGGCG
TCGAGGTTGTCGATTCCATGGTGCATGGCGGCCCCTACCCGGCCTCGACCAACTTCGGCGCAACCAGCGTCGGGACCATG
TCGATCCGCAGATTTCTGCGCCCCGTTGCCTACCAGAATTTCCCTGCCGGCCTGTTGCCCCAAGACCTGCGCAACTGA

Upstream 100 bases:

>100_bases
GACGCTCTTTGCCGAATGGCGGAAGGTGAGCGGCCGCTAAGCCGGCGTATCTTGAACAACGGAATCAGGACGGAGCCAGG
CTCCGCCGAGGAGAATAACA

Downstream 100 bases:

>100_bases
CATCGAGGAGTACCAAATTGATCGCCCCGACGGAACTTCGCGAGATCATTCGCAACGGCCTGCTGTCCTTTCCCGTCACC
CCTTTCGATGCCGAGGACCG

Product: putative fatty aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSWTPSGKHFIAGEWIAGTTTFQSEPAHGQAHDFAVGTTELVDRACRAAEAAFAAFSATTREERAIFLEAIAEEIDKRGE
AVTLIGTQETGLPEGRLNGERARTTGQLRLFADHIRKGAHLDASVDAAQPDRQPAPRPEIRLVQRPIGPVAVFGASNFPL
AFSTAGGDTAAALAAGCPVVVKGHSAHPGTGEIIAEAIAAAIERTGMPAGVFSLIQGGRRDVGTALVTHPAIKAVGFTGS
LAGGRALFDLCAQRPEPIPFFGELGSVNPMFLLPAATAARAEAIGSGWAGSLTLGAGQFCTKPGIAVVVDGPEADKFTSA
AKAALEKVAPQTMLTKGIATAYHDGADRLRASNAVAPVLAAKSADRDAAPNLFETNGSAWLADHSLSEEVFGPLGLVVRV
DSPEKMLALAESFQGQLTATIHMDDADLGLARDLLPILERKAGRLLVNGFPTGVEVVDSMVHGGPYPASTNFGATSVGTM
SIRRFLRPVAYQNFPAGLLPQDLRN

Sequences:

>Translated_505_residues
MSWTPSGKHFIAGEWIAGTTTFQSEPAHGQAHDFAVGTTELVDRACRAAEAAFAAFSATTREERAIFLEAIAEEIDKRGE
AVTLIGTQETGLPEGRLNGERARTTGQLRLFADHIRKGAHLDASVDAAQPDRQPAPRPEIRLVQRPIGPVAVFGASNFPL
AFSTAGGDTAAALAAGCPVVVKGHSAHPGTGEIIAEAIAAAIERTGMPAGVFSLIQGGRRDVGTALVTHPAIKAVGFTGS
LAGGRALFDLCAQRPEPIPFFGELGSVNPMFLLPAATAARAEAIGSGWAGSLTLGAGQFCTKPGIAVVVDGPEADKFTSA
AKAALEKVAPQTMLTKGIATAYHDGADRLRASNAVAPVLAAKSADRDAAPNLFETNGSAWLADHSLSEEVFGPLGLVVRV
DSPEKMLALAESFQGQLTATIHMDDADLGLARDLLPILERKAGRLLVNGFPTGVEVVDSMVHGGPYPASTNFGATSVGTM
SIRRFLRPVAYQNFPAGLLPQDLRN
>Mature_504_residues
SWTPSGKHFIAGEWIAGTTTFQSEPAHGQAHDFAVGTTELVDRACRAAEAAFAAFSATTREERAIFLEAIAEEIDKRGEA
VTLIGTQETGLPEGRLNGERARTTGQLRLFADHIRKGAHLDASVDAAQPDRQPAPRPEIRLVQRPIGPVAVFGASNFPLA
FSTAGGDTAAALAAGCPVVVKGHSAHPGTGEIIAEAIAAAIERTGMPAGVFSLIQGGRRDVGTALVTHPAIKAVGFTGSL
AGGRALFDLCAQRPEPIPFFGELGSVNPMFLLPAATAARAEAIGSGWAGSLTLGAGQFCTKPGIAVVVDGPEADKFTSAA
KAALEKVAPQTMLTKGIATAYHDGADRLRASNAVAPVLAAKSADRDAAPNLFETNGSAWLADHSLSEEVFGPLGLVVRVD
SPEKMLALAESFQGQLTATIHMDDADLGLARDLLPILERKAGRLLVNGFPTGVEVVDSMVHGGPYPASTNFGATSVGTMS
IRRFLRPVAYQNFPAGLLPQDLRN

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=406, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI25777721, Length=415, Percent_Identity=26.7469879518072, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI12007648, Length=446, Percent_Identity=23.0941704035874, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI115387104, Length=447, Percent_Identity=24.3847874720358, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI25952152, Length=424, Percent_Identity=22.1698113207547, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788042, Length=425, Percent_Identity=27.2941176470588, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789015, Length=436, Percent_Identity=27.7522935779816, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787558, Length=491, Percent_Identity=25.8655804480652, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081896, Length=456, Percent_Identity=27.4122807017544, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786504, Length=474, Percent_Identity=25.9493670886076, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787250, Length=317, Percent_Identity=30.5993690851735, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787684, Length=419, Percent_Identity=24.8210023866348, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082295, Length=529, Percent_Identity=23.2514177693762, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787715, Length=492, Percent_Identity=27.4390243902439, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71995606, Length=470, Percent_Identity=25.7446808510638, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71995613, Length=432, Percent_Identity=26.1574074074074, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551164, Length=443, Percent_Identity=24.1534988713318, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25143874, Length=469, Percent_Identity=24.5202558635394, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25143876, Length=469, Percent_Identity=24.5202558635394, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI133930964, Length=304, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319478, Length=437, Percent_Identity=24.7139588100687, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324950, Length=415, Percent_Identity=24.3373493975904, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323822, Length=480, Percent_Identity=24.375, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=461, Percent_Identity=24.5119305856833, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362580, Length=330, Percent_Identity=27.8787878787879, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI62472918, Length=330, Percent_Identity=27.8787878787879, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI62472926, Length=330, Percent_Identity=27.8787878787879, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI62472936, Length=330, Percent_Identity=27.8787878787879, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21356737, Length=330, Percent_Identity=27.8787878787879, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 52572; Mature: 52441

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWTPSGKHFIAGEWIAGTTTFQSEPAHGQAHDFAVGTTELVDRACRAAEAAFAAFSATT
CCCCCCCCEEEECCEEECCEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCC
REERAIFLEAIAEEIDKRGEAVTLIGTQETGLPEGRLNGERARTTGQLRLFADHIRKGAH
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCCC
LDASVDAAQPDRQPAPRPEIRLVQRPIGPVAVFGASNFPLAFSTAGGDTAAALAAGCPVV
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHHHHCCCCEE
VKGHSAHPGTGEIIAEAIAAAIERTGMPAGVFSLIQGGRRDVGTALVTHPAIKAVGFTGS
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCHHHHHCCCCCC
LAGGRALFDLCAQRPEPIPFFGELGSVNPMFLLPAATAARAEAIGSGWAGSLTLGAGQFC
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEECCCCHH
TKPGIAVVVDGPEADKFTSAAKAALEKVAPQTMLTKGIATAYHDGADRLRASNAVAPVLA
CCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHH
AKSADRDAAPNLFETNGSAWLADHSLSEEVFGPLGLVVRVDSPEKMLALAESFQGQLTAT
HCCCCCCCCCCCEECCCCEEEECCCCCHHHCCCEEEEEEECCHHHHHHHHHHCCCEEEEE
IHMDDADLGLARDLLPILERKAGRLLVNGFPTGVEVVDSMVHGGPYPASTNFGATSVGTM
EEECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHH
SIRRFLRPVAYQNFPAGLLPQDLRN
HHHHHHHHHHHCCCCCCCCCHHHCC
>Mature Secondary Structure 
SWTPSGKHFIAGEWIAGTTTFQSEPAHGQAHDFAVGTTELVDRACRAAEAAFAAFSATT
CCCCCCCEEEECCEEECCEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCC
REERAIFLEAIAEEIDKRGEAVTLIGTQETGLPEGRLNGERARTTGQLRLFADHIRKGAH
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCCCC
LDASVDAAQPDRQPAPRPEIRLVQRPIGPVAVFGASNFPLAFSTAGGDTAAALAAGCPVV
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCEEEECCCCCHHHHHHCCCCEE
VKGHSAHPGTGEIIAEAIAAAIERTGMPAGVFSLIQGGRRDVGTALVTHPAIKAVGFTGS
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCHHHHHCCCCCC
LAGGRALFDLCAQRPEPIPFFGELGSVNPMFLLPAATAARAEAIGSGWAGSLTLGAGQFC
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCEEEECCCCHH
TKPGIAVVVDGPEADKFTSAAKAALEKVAPQTMLTKGIATAYHDGADRLRASNAVAPVLA
CCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHH
AKSADRDAAPNLFETNGSAWLADHSLSEEVFGPLGLVVRVDSPEKMLALAESFQGQLTAT
HCCCCCCCCCCCEECCCCEEEECCCCCHHHCCCEEEEEEECCHHHHHHHHHHCCCEEEEE
IHMDDADLGLARDLLPILERKAGRLLVNGFPTGVEVVDSMVHGGPYPASTNFGATSVGTM
EEECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHH
SIRRFLRPVAYQNFPAGLLPQDLRN
HHHHHHHHHHHCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]