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The map label for this gene is yeiI [H]

Identifier: 116248845

GI number: 116248845

Start: 174836

End: 175999

Strand: Direct

Name: yeiI [H]

Synonym: pRL120174

Alternate gene names: 116248845

Gene position: 174836-175999 (Clockwise)

Preceding gene: 116248839

Following gene: 116248846

Centisome position: 20.1

GC content: 61.86

Gene sequence:

>1164_bases
TTGTTGTCCATATCAAAAATAACGAAACTTCAACCCAGTGAACTAGACAAGATGGATGACCTTGCCCCCCAGGAAGCGGC
CGTCCTGGCAATCATTAAGGACAACCCTTTCGCAGGGCAGCAGGAAATCGCGTCGATGCTCGGCCTGGCCCGCTCGACCG
TGGCTGCCCACATCGTCCAGCTGATGCAGAAGGGCTATATTCTCGGCCGCGGTTATGTGATGCCGGCCAGGACGCGGGCC
GTTTGCATCGGTGGCGCCGTGCTCGACCACAAGTACCGCGCCAAGGAAGCACTTGTGTTCGAAACCTCCAACCCGGTGGA
TGGCATTCGCAGTCTCGGCGGCGTTGCCCGCAACGTTGCGGAAAACCTTGCACTGCTGGGTACCTCGACGAGCTTCGTCT
CGATCGTCGGCGATGACGAAGGCGGAAGGGCGATCCTGAAGCATATGCGCGACCGCGGCATCGATGTGAGCCAGGTCGTC
ACCACCTCGGAACGCCCGACAGCCGAATATGCTGCGATCCTCGATCCACAGGGCGAACTTGTTCTCGGCATTGCCGACAT
GGGCATTTTCGACCTGCTTCTGCCGAACCATATCGAGCGGATCTGGCCGCATCTGGCCGCCGCCAGCTGGGTGTTTTCCG
ACTGTAACCCGCCCGCCGAAATGCTGGCAGCCCTGATCGCCAAGCGCCAGGGCGGCGCCCGCTTCAAGCTAGCGATCGAC
GCGGTCTCGACCCCCAAGGCTGCTCGCCTGCCGAAAAATCTGACCGGCATTGACCTCCTGTTCATGAATATCGACGAGGC
GAATTCGATCCTGAAGCGCCAGGGCCACGAAACGATCGAGGATGCCCGCGAAGCCGCGCTTGCGCTGCAGGCAGCCGGCG
CACGGGAAGCGATCGTCACCATGGCTGCACGCGGCATCGCAGTTGCCGGGATCGAAGGCGCCAAGACGTTTCCGGCGGTC
ACTGCCCGGCCGATCGACATTACCGGCGCGGGCGATGCCATGATTGCTGGTACGCTTCACAGCATTCTGAACGGCGAAAA
CACCTATGCCGCGGCCCGCACCGGCGCGCTGCTCGCCACGCTGACGACGGAAAGCACCGCCAGCGTCCACACCGAATTGT
CCGAACGCTTCCTCGAAGCGAACATGCACCGGCTTGTCGGCTAA

Upstream 100 bases:

>100_bases
CCGGCCCCGACACCGTTGGACGACGCGGTATTGGCGTTCGATACGGACATAAGCCTACCTCCAAACTCGACTGACAAACA
GATGTTGACAAAAACATCTG

Downstream 100 bases:

>100_bases
CCTCGCCGGCTGAATCAAGGAATTGTCACAATGACCCTCATGAAGCCCCGACTGAGCCGCGAAATGGCCGAAGCCATTGC
AGCCGGCAGCCCGGTCGTAG

Product: PfkB family kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLSISKITKLQPSELDKMDDLAPQEAAVLAIIKDNPFAGQQEIASMLGLARSTVAAHIVQLMQKGYILGRGYVMPARTRA
VCIGGAVLDHKYRAKEALVFETSNPVDGIRSLGGVARNVAENLALLGTSTSFVSIVGDDEGGRAILKHMRDRGIDVSQVV
TTSERPTAEYAAILDPQGELVLGIADMGIFDLLLPNHIERIWPHLAAASWVFSDCNPPAEMLAALIAKRQGGARFKLAID
AVSTPKAARLPKNLTGIDLLFMNIDEANSILKRQGHETIEDAREAALALQAAGAREAIVTMAARGIAVAGIEGAKTFPAV
TARPIDITGAGDAMIAGTLHSILNGENTYAAARTGALLATLTTESTASVHTELSERFLEANMHRLVG

Sequences:

>Translated_387_residues
MLSISKITKLQPSELDKMDDLAPQEAAVLAIIKDNPFAGQQEIASMLGLARSTVAAHIVQLMQKGYILGRGYVMPARTRA
VCIGGAVLDHKYRAKEALVFETSNPVDGIRSLGGVARNVAENLALLGTSTSFVSIVGDDEGGRAILKHMRDRGIDVSQVV
TTSERPTAEYAAILDPQGELVLGIADMGIFDLLLPNHIERIWPHLAAASWVFSDCNPPAEMLAALIAKRQGGARFKLAID
AVSTPKAARLPKNLTGIDLLFMNIDEANSILKRQGHETIEDAREAALALQAAGAREAIVTMAARGIAVAGIEGAKTFPAV
TARPIDITGAGDAMIAGTLHSILNGENTYAAARTGALLATLTTESTASVHTELSERFLEANMHRLVG
>Mature_387_residues
MLSISKITKLQPSELDKMDDLAPQEAAVLAIIKDNPFAGQQEIASMLGLARSTVAAHIVQLMQKGYILGRGYVMPARTRA
VCIGGAVLDHKYRAKEALVFETSNPVDGIRSLGGVARNVAENLALLGTSTSFVSIVGDDEGGRAILKHMRDRGIDVSQVV
TTSERPTAEYAAILDPQGELVLGIADMGIFDLLLPNHIERIWPHLAAASWVFSDCNPPAEMLAALIAKRQGGARFKLAID
AVSTPKAARLPKNLTGIDLLFMNIDEANSILKRQGHETIEDAREAALALQAAGAREAIVTMAARGIAVAGIEGAKTFPAV
TARPIDITGAGDAMIAGTLHSILNGENTYAAARTGALLATLTTESTASVHTELSERFLEANMHRLVG

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788484, Length=345, Percent_Identity=32.463768115942, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788491, Length=275, Percent_Identity=29.0909090909091, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 41013; Mature: 41013

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSISKITKLQPSELDKMDDLAPQEAAVLAIIKDNPFAGQQEIASMLGLARSTVAAHIVQ
CCCHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LMQKGYILGRGYVMPARTRAVCIGGAVLDHKYRAKEALVFETSNPVDGIRSLGGVARNVA
HHHCCEEEECCEECCCCCCEEEECCHHHCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHH
ENLALLGTSTSFVSIVGDDEGGRAILKHMRDRGIDVSQVVTTSERPTAEYAAILDPQGEL
HHHEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHEECCCCCCCHHHEEECCCCCE
VLGIADMGIFDLLLPNHIERIWPHLAAASWVFSDCNPPAEMLAALIAKRQGGARFKLAID
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEE
AVSTPKAARLPKNLTGIDLLFMNIDEANSILKRQGHETIEDAREAALALQAAGAREAIVT
CCCCCHHHHCCCCCCCEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHH
MAARGIAVAGIEGAKTFPAVTARPIDITGAGDAMIAGTLHSILNGENTYAAARTGALLAT
HHHCCEEEECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCEEEEE
LTTESTASVHTELSERFLEANMHRLVG
EECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSISKITKLQPSELDKMDDLAPQEAAVLAIIKDNPFAGQQEIASMLGLARSTVAAHIVQ
CCCHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LMQKGYILGRGYVMPARTRAVCIGGAVLDHKYRAKEALVFETSNPVDGIRSLGGVARNVA
HHHCCEEEECCEECCCCCCEEEECCHHHCCHHHCCEEEEEECCCCHHHHHHHHHHHHHHH
ENLALLGTSTSFVSIVGDDEGGRAILKHMRDRGIDVSQVVTTSERPTAEYAAILDPQGEL
HHHEEEECCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHEECCCCCCCHHHEEECCCCCE
VLGIADMGIFDLLLPNHIERIWPHLAAASWVFSDCNPPAEMLAALIAKRQGGARFKLAID
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEE
AVSTPKAARLPKNLTGIDLLFMNIDEANSILKRQGHETIEDAREAALALQAAGAREAIVT
CCCCCHHHHCCCCCCCEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHH
MAARGIAVAGIEGAKTFPAVTARPIDITGAGDAMIAGTLHSILNGENTYAAARTGALLAT
HHHCCEEEECCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCEEEEE
LTTESTASVHTELSERFLEANMHRLVG
EECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 2460435 [H]