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The map label for this gene is kipA [H]

Identifier: 116248824

GI number: 116248824

Start: 150205

End: 151176

Strand: Reverse

Name: kipA [H]

Synonym: pRL120150

Alternate gene names: 116248824

Gene position: 151176-150205 (Counterclockwise)

Preceding gene: 116248825

Following gene: 116248821

Centisome position: 17.38

GC content: 68.11

Gene sequence:

>972_bases
ATGGCCATTAAGGTGCTGCACCCGGGACTATCGACCAGCGTCCAGGATCTCGGCCGTCCGGGCTATTTCCACCTCGGCAT
CCCGATCGGCGGCGCCATGGACCGCTACGCCATGCGTGCCGCCAATCTGCTCGTCGGCAACGACGAAGGGGCGGCGGGTC
TCGAGGCGGTCTTCATGGGACCGAAGCTCGAATTCGCCGAGGATGCCCTGGTGGCCGTCACCGGTGCCGACATGCCGGCC
AAGGTCGACGGCGTGGGGCAGCCCGGCTGGACGGCTTTCAAGGTCAAGGCCGGCCAGGTGTTGAGCTTCGACTTCCTGAA
ATCCGGCGCGCGCATCCTGATCGCGGTCGCGGGCGGCATCGACGTGCCGGAAGCGCTCGGCAGCCGCTCCACCTATCCGA
TCGGCGCGCTCGGCGGCTACAAGGGCAGGGCGCTGGCAGCCGGCGACGCACTGCCGGTCGGAAAGGCCGGCCTTGCCGAG
GAAGGAAAAAGCGTCGCCGAAGAGCTGCGGCGCAGACCCGGAACGCCGGCAGAGCTGCGCGTGCTGCCGGGGCTCTACTG
GGACCGGCTGACGGATGCCGCCAAGGCGAGCTTCTTCGCCGACGAGTGGAAGGTGGCGCCTGAGGCCGACCGCATGGGCT
ACCGCTTCCGCGGCGGGCGCAAGCTCGACTTCCTGGACCGCAAGCAGCCCTTCGGCGCCGGTTCCGATCCGTCGAACATC
GTCGACAGCTGCTACCCCTACGGCTCGATTCAGGTGCCGGGCGGAACGGAGCCGATCATCCTTCATCGCGACGCTGTCTC
CGGCGGCGGCTATTTCATGGTCGGCACGGTAATCTCGGCGGACATGGACCTCATCGGCCAGTTACAGCCGCATACACCGG
CGCGGTTCGTCGAGGTGACGATGGATGAGGCGCTGAAGGCGAGGGCCGATCGCGCAGCGCTGCTCGACCGCCTCCGCCAG
AGCCTGTCGTGA

Upstream 100 bases:

>100_bases
AAGAAGCTCTTCAGCCCGCCGATCCGCGAGGTCCGGTTCGATCTTCGCGAATTCAGCAAGGATATCCACGGTTACAACGC
CGCGCTGGAGGGCGTTCTCC

Downstream 100 bases:

>100_bases
GGTGACGAGGATGGCCTGTCGATCACTCGACGTGCGTCAGGTAATCGGCGGTCACGCTCGGGCCGGGAATGATGGCGACG
ATCTTCATCTGGGCGATCAT

Product: putative urea amidolyase related protein

Products: NA

Alternate protein names: Protein kipA [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAIKVLHPGLSTSVQDLGRPGYFHLGIPIGGAMDRYAMRAANLLVGNDEGAAGLEAVFMGPKLEFAEDALVAVTGADMPA
KVDGVGQPGWTAFKVKAGQVLSFDFLKSGARILIAVAGGIDVPEALGSRSTYPIGALGGYKGRALAAGDALPVGKAGLAE
EGKSVAEELRRRPGTPAELRVLPGLYWDRLTDAAKASFFADEWKVAPEADRMGYRFRGGRKLDFLDRKQPFGAGSDPSNI
VDSCYPYGSIQVPGGTEPIILHRDAVSGGGYFMVGTVISADMDLIGQLQPHTPARFVEVTMDEALKARADRAALLDRLRQ
SLS

Sequences:

>Translated_323_residues
MAIKVLHPGLSTSVQDLGRPGYFHLGIPIGGAMDRYAMRAANLLVGNDEGAAGLEAVFMGPKLEFAEDALVAVTGADMPA
KVDGVGQPGWTAFKVKAGQVLSFDFLKSGARILIAVAGGIDVPEALGSRSTYPIGALGGYKGRALAAGDALPVGKAGLAE
EGKSVAEELRRRPGTPAELRVLPGLYWDRLTDAAKASFFADEWKVAPEADRMGYRFRGGRKLDFLDRKQPFGAGSDPSNI
VDSCYPYGSIQVPGGTEPIILHRDAVSGGGYFMVGTVISADMDLIGQLQPHTPARFVEVTMDEALKARADRAALLDRLRQ
SLS
>Mature_322_residues
AIKVLHPGLSTSVQDLGRPGYFHLGIPIGGAMDRYAMRAANLLVGNDEGAAGLEAVFMGPKLEFAEDALVAVTGADMPAK
VDGVGQPGWTAFKVKAGQVLSFDFLKSGARILIAVAGGIDVPEALGSRSTYPIGALGGYKGRALAAGDALPVGKAGLAEE
GKSVAEELRRRPGTPAELRVLPGLYWDRLTDAAKASFFADEWKVAPEADRMGYRFRGGRKLDFLDRKQPFGAGSDPSNIV
DSCYPYGSIQVPGGTEPIILHRDAVSGGGYFMVGTVISADMDLIGQLQPHTPARFVEVTMDEALKARADRAALLDRLRQS
LS

Specific function: Counteracts the inhibitory action of kipI on sporulation. May bind to kipI, preventing its function as an inhibitor of kinase A [H]

COG id: COG1984

COG function: function code E; Allophanate hydrolase subunit 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786930, Length=319, Percent_Identity=36.3636363636364, Blast_Score=181, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6319685, Length=325, Percent_Identity=34.4615384615385, Blast_Score=159, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003778 [H]

Pfam domain/function: PF02626 AHS2 [H]

EC number: NA

Molecular weight: Translated: 34144; Mature: 34013

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVLHPGLSTSVQDLGRPGYFHLGIPIGGAMDRYAMRAANLLVGNDEGAAGLEAVFMG
CEEEEECCCCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHEEEECCCCCCCEEEEEEC
PKLEFAEDALVAVTGADMPAKVDGVGQPGWTAFKVKAGQVLSFDFLKSGARILIAVAGGI
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHCCCEEEEEEECCC
DVPEALGSRSTYPIGALGGYKGRALAAGDALPVGKAGLAEEGKSVAEELRRRPGTPAELR
CCHHHHCCCCCCCEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
VLPGLYWDRLTDAAKASFFADEWKVAPEADRMGYRFRGGRKLDFLDRKQPFGAGSDPSNI
ECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEECCCCEECCCCCCCCCCCCCCHHHH
VDSCYPYGSIQVPGGTEPIILHRDAVSGGGYFMVGTVISADMDLIGQLQPHTPARFVEVT
HHHHCCCCCEECCCCCCCEEEEECCCCCCCEEEEEEHHHCCHHHHHCCCCCCCHHEEEEE
MDEALKARADRAALLDRLRQSLS
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIKVLHPGLSTSVQDLGRPGYFHLGIPIGGAMDRYAMRAANLLVGNDEGAAGLEAVFMG
EEEEECCCCCHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHEEEECCCCCCCEEEEEEC
PKLEFAEDALVAVTGADMPAKVDGVGQPGWTAFKVKAGQVLSFDFLKSGARILIAVAGGI
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHCCCEEEEEEECCC
DVPEALGSRSTYPIGALGGYKGRALAAGDALPVGKAGLAEEGKSVAEELRRRPGTPAELR
CCHHHHCCCCCCCEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
VLPGLYWDRLTDAAKASFFADEWKVAPEADRMGYRFRGGRKLDFLDRKQPFGAGSDPSNI
ECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEECCCCEECCCCCCCCCCCCCCHHHH
VDSCYPYGSIQVPGGTEPIILHRDAVSGGGYFMVGTVISADMDLIGQLQPHTPARFVEVT
HHHHCCCCCEECCCCCCCEEEEECCCCCCCEEEEEEHHHCCHHHHHCCCCCCCHHEEEEE
MDEALKARADRAALLDRLRQSLS
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]