BacMap

Definition	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL12, complete sequence.
Accession	NC_008378
Length	870,021

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The map label for this gene is fabG [H]

Identifier: 116248793

GI number: 116248793

Start: 117411

End: 118196

Strand: Reverse

Name: fabG [H]

Synonym: pRL120119

Alternate gene names: 116248793

Gene position: 118196-117411 (Counterclockwise)

Preceding gene: 116248794

Following gene: 116248779

Centisome position: 13.59

GC content: 60.69

Gene sequence:

>786_bases
ATGGATCTCGGATTGAAAGGCAAGACTGCCCTGGTATTGGGCGCCGGCGGCGGGCTTGGTGGGGCAATTGCAAAAACCCT
TGCCGTCGAAGGCGCGCGGATCGCGGTTGCAGATATCAACAGGGAAGCAGCGGAAAAAACGGTTACCGATATCCGCACGG
CTGGCGGCTTAGCGATGGCGCTTCAATGGGACCTTGCCGAACTCGGCGTGATCGAGCCCAATCTCGCCGCCATCGACGAG
CAGCTCGGCTCGGTAGACGTTCTTGTCAATATCACCGGCGGCCCGCCGCCGACGCTCGTTTCCGGTCAGAATGCCGAGAG
CTGGCGCAAATACTTCGACAGCATGGTTCTGTCGGTCATAGCAATCTCCGATGCCGTACTTCCCCGGATGCGTGAAAAGA
AGTGGGGACGCATCATCACCTCGACATCATCTGGCGTCGTCGCGCCCATTCCCAATCTTGGCCTGTCGAATGCCCTGCGC
ATGTCGCTTCTCGGATGGTCGAAAACACTGGCGGGCGAGGTCGGTCGTGATGGCGTGACCGTCAATGTCGTGTTGCCAGG
CCGTGTCGCCACACAGCGTATCGCCTTCCTCGACGAACAGAAGGCGAAGCGCGAAGGGAAGGCCGTCGAAGAGGTTTCAG
CGGCAAGCACTGCATCGATCCCCGTCGGGCGCTACGGCGAACCGCAGGAATATGCCGACGTTGTCGCGTTCATGGCAAGC
AGCCGCGCCTCCTATCTGACCGGGTCGGTGATCCGGGTGGACGGTGGTCTAATCTCGAGCGTGTGA

Upstream 100 bases:

>100_bases
GCTACATGACCGGCGTTAACCTGATGGTCGATGGCGGCTGGATGGCGGGCTGATGATCACAGCGTATGAAGATCGCCAAT
AACGGAAAGGAAAACGGACC

Downstream 100 bases:

>100_bases
TTGCCCCTGCCTTCGATTTCTGTTGGCAAGCAGGGCCTTTGACTGAAATTTCGACTGCCTTGACTGCGAGAAGAAACCAT
CGGTTGGCCAGCGATGTTTG

Product: putative short-chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MDLGLKGKTALVLGAGGGLGGAIAKTLAVEGARIAVADINREAAEKTVTDIRTAGGLAMALQWDLAELGVIEPNLAAIDE
QLGSVDVLVNITGGPPPTLVSGQNAESWRKYFDSMVLSVIAISDAVLPRMREKKWGRIITSTSSGVVAPIPNLGLSNALR
MSLLGWSKTLAGEVGRDGVTVNVVLPGRVATQRIAFLDEQKAKREGKAVEEVSAASTASIPVGRYGEPQEYADVVAFMAS
SRASYLTGSVIRVDGGLISSV

Sequences:

>Translated_261_residues
MDLGLKGKTALVLGAGGGLGGAIAKTLAVEGARIAVADINREAAEKTVTDIRTAGGLAMALQWDLAELGVIEPNLAAIDE
QLGSVDVLVNITGGPPPTLVSGQNAESWRKYFDSMVLSVIAISDAVLPRMREKKWGRIITSTSSGVVAPIPNLGLSNALR
MSLLGWSKTLAGEVGRDGVTVNVVLPGRVATQRIAFLDEQKAKREGKAVEEVSAASTASIPVGRYGEPQEYADVVAFMAS
SRASYLTGSVIRVDGGLISSV
>Mature_261_residues
MDLGLKGKTALVLGAGGGLGGAIAKTLAVEGARIAVADINREAAEKTVTDIRTAGGLAMALQWDLAELGVIEPNLAAIDE
QLGSVDVLVNITGGPPPTLVSGQNAESWRKYFDSMVLSVIAISDAVLPRMREKKWGRIITSTSSGVVAPIPNLGLSNALR
MSLLGWSKTLAGEVGRDGVTVNVVLPGRVATQRIAFLDEQKAKREGKAVEEVSAASTASIPVGRYGEPQEYADVVAFMAS
SRASYLTGSVIRVDGGLISSV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=31.7460317460317, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=31.3207547169811, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=29.4573643410853, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=27.843137254902, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=24.6153846153846, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=27.1276595744681, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=213, Percent_Identity=27.6995305164319, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI31542939, Length=216, Percent_Identity=27.3148148148148, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=37.2093023255814, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=30.1158301158301, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=30.4347826086957, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=29.2490118577075, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=26.615969581749, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=29.5454545454545, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=28.2945736434109, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789208, Length=268, Percent_Identity=27.2388059701493, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=266, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=30.1526717557252, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=30, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=29.4573643410853, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=32.0610687022901, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=26.2548262548263, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=28.0632411067194, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=27.843137254902, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=25.5639097744361, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=33, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=29.296875, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=29.9212598425197, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=27.6119402985075, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=27.5193798449612, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=29.2307692307692, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=26.8939393939394, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=26.8199233716475, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=27.3764258555133, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=26.5917602996255, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.5151515151515, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=26.0377358490566, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=26.0536398467433, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=26.5917602996255, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=24.907063197026, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=31.4720812182741, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=24.031007751938, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=28.7878787878788, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=31.4176245210728, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=27.5590551181102, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=32.994923857868, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355631, Length=178, Percent_Identity=28.6516853932584, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=29.6875, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=31.25, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649181, Length=205, Percent_Identity=31.219512195122, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27083; Mature: 27083

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLKGKTALVLGAGGGLGGAIAKTLAVEGARIAVADINREAAEKTVTDIRTAGGLAMA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEE
LQWDLAELGVIEPNLAAIDEQLGSVDVLVNITGGPPPTLVSGQNAESWRKYFDSMVLSVI
EEECHHHCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHH
AISDAVLPRMREKKWGRIITSTSSGVVAPIPNLGLSNALRMSLLGWSKTLAGEVGRDGVT
HHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
VNVVLPGRVATQRIAFLDEQKAKREGKAVEEVSAASTASIPVGRYGEPQEYADVVAFMAS
EEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
SRASYLTGSVIRVDGGLISSV
CCCHHHCCCEEEECCCHHCCC
>Mature Secondary Structure
MDLGLKGKTALVLGAGGGLGGAIAKTLAVEGARIAVADINREAAEKTVTDIRTAGGLAMA
CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEE
LQWDLAELGVIEPNLAAIDEQLGSVDVLVNITGGPPPTLVSGQNAESWRKYFDSMVLSVI
EEECHHHCCCCCCCHHHHHHHCCCEEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHH
AISDAVLPRMREKKWGRIITSTSSGVVAPIPNLGLSNALRMSLLGWSKTLAGEVGRDGVT
HHHHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
VNVVLPGRVATQRIAFLDEQKAKREGKAVEEVSAASTASIPVGRYGEPQEYADVVAFMAS
EEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
SRASYLTGSVIRVDGGLISSV
CCCHHHCCCEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]