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The map label for this gene is yrpG [H]

Identifier: 116248784

GI number: 116248784

Start: 103454

End: 104491

Strand: Direct

Name: yrpG [H]

Synonym: pRL120108

Alternate gene names: 116248784

Gene position: 103454-104491 (Clockwise)

Preceding gene: 116248783

Following gene: 116248785

Centisome position: 11.89

GC content: 65.03

Gene sequence:

>1038_bases
ATGAATATGGATTATCGCAAGCTCGGTCCCAGCGGGACCGTCGTCACCGCCTATTGCCTCGGCACCATGACCTTCGGCGC
GGAGGCCGATGAGGCCGCCTCCCACAAGCTGCTCGACGATTATTTCGCCTGGGGCGGCAATTTCATCGATACCGCCGATG
TCTATAGCGCCGGCAAGTCGGAAGAGATCATCGGACGCTGGCTGAAGGCGCGCCCGACCGAGGCCCGCCAGGCGATCGTC
GCCACCAAGGGGCGGTTCCCGATGGGCAACGGCCCCAACGATATCGGCCTGTCGCGCCGGCATCTTAGCCAGGCGCTCGA
CGATTCGCTCCGCCGCCTCGGCCTCGAGCAGATCGACCTTTACCAGATGCATGCCTGGGACGCGCTGACGCCGATCGAGG
AAACGCTGCGTTTCCTCGACGATGCGGTTTCCTCCGGCAAGATCGGCTATTACGGCTTCTCCAATTATGTCGGCTGGCAT
ATCGCCAAGGCCTCCGAGATCGCCAAGGCGCGCGGCTATACCCGTCCGGTGACGCTGCAGCCGCAGTATAACCTGCTGGT
GCGCGACATCGAACTCGAGATCGTCGCGGCCTGCCAGGATGCCGGCATGGGTCTGTTGCCGTGGTCGCCACTCGGCGGCG
GCTGGCTGACCGGCAAATACAAGCGCGACGAGATGCCGACGGGCGCCACCCGCCTCGGCGAAAACCCCAATCGCGGCGGT
GAATCCTATGCGCCGCGCAATGCGATGGAGAGAACCTGGGCGATCATCGCTGTCGTCGAGGAGATCGCCAAGGCGCATGG
CGTCAGCATGGCGCAGGTGGCGCTCGGCTGGACGGCGGCGCAGCCGGCGATCACCTCCGTCATCCTCGGCGCCCGCACGC
CGGAACAGCTCGCTGACAATCTCGGCGCCATGAAGCTCAAGCTCTCCGACGACGACATGGCGCGGTTGAACGAGGTGAGT
GCGCCCCAGCCGTTCGACTACCCCTATGGCAAGGGCGGCATCAACCAGCGCCATCGCAAGATCGAGGGTGGGCGGTAG

Upstream 100 bases:

>100_bases
CGTTTGGGACGTGTGAAGGCAGTTCGCTGCTCGTTCTTTCACCGCCGTCGACATCGAAATGACAGCCGCCGCTGATGCCG
CAGTTGTGTTCAAAGAGGAG

Downstream 100 bases:

>100_bases
TTCGTGGACTGGGACGGTGGCCGAGCCGCCGTCCGGTTTGCCTCGTCACGGCGCCTGTCTCATCGGTCGTCCGCCAAGCC
GGCATTTCGATGGAACTCCA

Product: MocA family oxido-reductase/dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNMDYRKLGPSGTVVTAYCLGTMTFGAEADEAASHKLLDDYFAWGGNFIDTADVYSAGKSEEIIGRWLKARPTEARQAIV
ATKGRFPMGNGPNDIGLSRRHLSQALDDSLRRLGLEQIDLYQMHAWDALTPIEETLRFLDDAVSSGKIGYYGFSNYVGWH
IAKASEIAKARGYTRPVTLQPQYNLLVRDIELEIVAACQDAGMGLLPWSPLGGGWLTGKYKRDEMPTGATRLGENPNRGG
ESYAPRNAMERTWAIIAVVEEIAKAHGVSMAQVALGWTAAQPAITSVILGARTPEQLADNLGAMKLKLSDDDMARLNEVS
APQPFDYPYGKGGINQRHRKIEGGR

Sequences:

>Translated_345_residues
MNMDYRKLGPSGTVVTAYCLGTMTFGAEADEAASHKLLDDYFAWGGNFIDTADVYSAGKSEEIIGRWLKARPTEARQAIV
ATKGRFPMGNGPNDIGLSRRHLSQALDDSLRRLGLEQIDLYQMHAWDALTPIEETLRFLDDAVSSGKIGYYGFSNYVGWH
IAKASEIAKARGYTRPVTLQPQYNLLVRDIELEIVAACQDAGMGLLPWSPLGGGWLTGKYKRDEMPTGATRLGENPNRGG
ESYAPRNAMERTWAIIAVVEEIAKAHGVSMAQVALGWTAAQPAITSVILGARTPEQLADNLGAMKLKLSDDDMARLNEVS
APQPFDYPYGKGGINQRHRKIEGGR
>Mature_345_residues
MNMDYRKLGPSGTVVTAYCLGTMTFGAEADEAASHKLLDDYFAWGGNFIDTADVYSAGKSEEIIGRWLKARPTEARQAIV
ATKGRFPMGNGPNDIGLSRRHLSQALDDSLRRLGLEQIDLYQMHAWDALTPIEETLRFLDDAVSSGKIGYYGFSNYVGWH
IAKASEIAKARGYTRPVTLQPQYNLLVRDIELEIVAACQDAGMGLLPWSPLGGGWLTGKYKRDEMPTGATRLGENPNRGG
ESYAPRNAMERTWAIIAVVEEIAKAHGVSMAQVALGWTAAQPAITSVILGARTPEQLADNLGAMKLKLSDDDMARLNEVS
APQPFDYPYGKGGINQRHRKIEGGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=331, Percent_Identity=30.8157099697885, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI27436964, Length=330, Percent_Identity=30.3030303030303, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI4504825, Length=329, Percent_Identity=30.6990881458967, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI27436962, Length=330, Percent_Identity=30.3030303030303, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI27436966, Length=330, Percent_Identity=30, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27436971, Length=306, Percent_Identity=30.0653594771242, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI41152114, Length=302, Percent_Identity=32.1192052980132, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI41327764, Length=305, Percent_Identity=32.1311475409836, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI223718702, Length=303, Percent_Identity=32.013201320132, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI223718708, Length=165, Percent_Identity=33.9393939393939, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=36.6366366366366, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789199, Length=354, Percent_Identity=33.6158192090396, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=34.5679012345679, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788070, Length=333, Percent_Identity=29.4294294294294, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788081, Length=288, Percent_Identity=28.125, Blast_Score=88, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=28.4457478005865, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323998, Length=318, Percent_Identity=30.188679245283, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319958, Length=308, Percent_Identity=29.8701298701299, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319951, Length=333, Percent_Identity=30.6306306306306, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6322615, Length=258, Percent_Identity=29.0697674418605, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321052, Length=151, Percent_Identity=33.112582781457, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640980, Length=349, Percent_Identity=24.3553008595989, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45549126, Length=349, Percent_Identity=24.3553008595989, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646155, Length=339, Percent_Identity=27.1386430678466, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646159, Length=256, Percent_Identity=28.90625, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37766; Mature: 37766

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMDYRKLGPSGTVVTAYCLGTMTFGAEADEAASHKLLDDYFAWGGNFIDTADVYSAGKS
CCCCCCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCC
EEIIGRWLKARPTEARQAIVATKGRFPMGNGPNDIGLSRRHLSQALDDSLRRLGLEQIDL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
YQMHAWDALTPIEETLRFLDDAVSSGKIGYYGFSNYVGWHIAKASEIAKARGYTRPVTLQ
HHHHHCHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEC
PQYNLLVRDIELEIVAACQDAGMGLLPWSPLGGGWLTGKYKRDEMPTGATRLGENPNRGG
CCCCEEEEEEEEEEEEEHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHCCCCCCCCC
ESYAPRNAMERTWAIIAVVEEIAKAHGVSMAQVALGWTAAQPAITSVILGARTPEQLADN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHC
LGAMKLKLSDDDMARLNEVSAPQPFDYPYGKGGINQRHRKIEGGR
CCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MNMDYRKLGPSGTVVTAYCLGTMTFGAEADEAASHKLLDDYFAWGGNFIDTADVYSAGKS
CCCCCCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCC
EEIIGRWLKARPTEARQAIVATKGRFPMGNGPNDIGLSRRHLSQALDDSLRRLGLEQIDL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
YQMHAWDALTPIEETLRFLDDAVSSGKIGYYGFSNYVGWHIAKASEIAKARGYTRPVTLQ
HHHHHCHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEC
PQYNLLVRDIELEIVAACQDAGMGLLPWSPLGGGWLTGKYKRDEMPTGATRLGENPNRGG
CCCCEEEEEEEEEEEEEHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHCCCCCCCCC
ESYAPRNAMERTWAIIAVVEEIAKAHGVSMAQVALGWTAAQPAITSVILGARTPEQLADN
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCHHHHHHHHCCCCHHHHHHC
LGAMKLKLSDDDMARLNEVSAPQPFDYPYGKGGINQRHRKIEGGR
CCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]