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The map label for this gene is yrbE [H]

Identifier: 116248706

GI number: 116248706

Start: 29268

End: 30344

Strand: Direct

Name: yrbE [H]

Synonym: pRL120030

Alternate gene names: 116248706

Gene position: 29268-30344 (Clockwise)

Preceding gene: 116248705

Following gene: 116248707

Centisome position: 3.36

GC content: 59.89

Gene sequence:

>1077_bases
ATGCCAGCAAAACAGGAACGACGTCTCCGCATCGGCGTATTGGGAGCGGGCCAGATTGCCCAGGCCGCGCACTTCGAGAG
CTGCACGAAGGCAGCCAATGCCGACCTCTATGCGATTTGCGACGTCGCCGAGGATCTCCGCGAACGCATGGCTATCACCC
ACGGGGCAGAAAAAACCTATGGCGATTACGATCAGATGCTGGCCGATCCCGACCTCGATGCCGTGGTCATTGCGACGGCC
GATGCCTTTCACGTCCCGGCTTCCCTTCGCGCCCTTCAGGCGGGCAAACATGTCCTCTGCGAAAAACCGGTCGGCGTCAC
CATCGAGGAATGCCTTGAACTGAAGGCGGCAGTCGACAAGTCGGGAAAGGTGTTTCAGGTCGGGCACATGAAGCGTTTCG
ACGCCGGGCTCCAAGCTGCCAAATCCTTCATCCGCGATGAAATGGGCGAGATGGTCGCTCTGAAAGCATGGTATTGCGAC
AGCACGCACCGCTATCCGATGACCGATGCGGTCCAGCCTCTGATCGTCACCAGCGCCAATGCGAAGAAACCCTCCACCAA
TCCGAAGGCCGACCTGAGGCGCTACTATATGCTTGCGCACGGTTGCCATCTGATCGACACGGCACGTTATTTCGCCGGCG
ACATCGTTTCCGTCAACGCTCGTCTGTCGGAGCGAGCCGGTATCTGGTGCTGGTTCGTGGACGTGGAATTTGCCTCCGGC
ACGCTCGGCCATCTCGATCTCACCGTCCAGGTGCGCATGGACTGGCACGAAGGCTTTCAGATCTACGGCAAGAACGGCAG
CATTTTGGGCAAGACCTATAACCCATGGTATTACAAGACCAGCGAGGTGGACATTTTCCGGGAAGTGGACGGAGCCACCC
ATCGCGTTCTCGGTGCCGACGGCCATTTCTATCGCCGTCAGGTCGAAGGCTTCGCCCGCACCATTCTGGATGGCGCCGTA
ATGGAAGGCGCCGACATCGATGATGGTCTGGCATCCGTCCGGGCCATGGTCGCGGTTGCGCGCTCCGTCGAAAACGGCAA
GACGGTTGCGCTGGCTGACGTCACGGGTGGCGTGTGA

Upstream 100 bases:

>100_bases
TCCAGCCAGAAGACGTCGGCGACGTTTAATGTCTTGAAAGCATTCCATCCGACGCCGAAACCAGCATTCATCTTCAATAT
CCGATCCAAAGGGCTTATCG

Downstream 100 bases:

>100_bases
TGAAGCTCGGCATCTTCGCAAAGACCTTCGAGGGAACGGAACCCGCAACCGTTCTCAACTCGGTCGCAGGCGCCGGGTTC
AACTGCGCACAATACAATAT

Product: GFO/IDH/MocA family oxidoreductase/dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MPAKQERRLRIGVLGAGQIAQAAHFESCTKAANADLYAICDVAEDLRERMAITHGAEKTYGDYDQMLADPDLDAVVIATA
DAFHVPASLRALQAGKHVLCEKPVGVTIEECLELKAAVDKSGKVFQVGHMKRFDAGLQAAKSFIRDEMGEMVALKAWYCD
STHRYPMTDAVQPLIVTSANAKKPSTNPKADLRRYYMLAHGCHLIDTARYFAGDIVSVNARLSERAGIWCWFVDVEFASG
TLGHLDLTVQVRMDWHEGFQIYGKNGSILGKTYNPWYYKTSEVDIFREVDGATHRVLGADGHFYRRQVEGFARTILDGAV
MEGADIDDGLASVRAMVAVARSVENGKTVALADVTGGV

Sequences:

>Translated_358_residues
MPAKQERRLRIGVLGAGQIAQAAHFESCTKAANADLYAICDVAEDLRERMAITHGAEKTYGDYDQMLADPDLDAVVIATA
DAFHVPASLRALQAGKHVLCEKPVGVTIEECLELKAAVDKSGKVFQVGHMKRFDAGLQAAKSFIRDEMGEMVALKAWYCD
STHRYPMTDAVQPLIVTSANAKKPSTNPKADLRRYYMLAHGCHLIDTARYFAGDIVSVNARLSERAGIWCWFVDVEFASG
TLGHLDLTVQVRMDWHEGFQIYGKNGSILGKTYNPWYYKTSEVDIFREVDGATHRVLGADGHFYRRQVEGFARTILDGAV
MEGADIDDGLASVRAMVAVARSVENGKTVALADVTGGV
>Mature_357_residues
PAKQERRLRIGVLGAGQIAQAAHFESCTKAANADLYAICDVAEDLRERMAITHGAEKTYGDYDQMLADPDLDAVVIATAD
AFHVPASLRALQAGKHVLCEKPVGVTIEECLELKAAVDKSGKVFQVGHMKRFDAGLQAAKSFIRDEMGEMVALKAWYCDS
THRYPMTDAVQPLIVTSANAKKPSTNPKADLRRYYMLAHGCHLIDTARYFAGDIVSVNARLSERAGIWCWFVDVEFASGT
LGHLDLTVQVRMDWHEGFQIYGKNGSILGKTYNPWYYKTSEVDIFREVDGATHRVLGADGHFYRRQVEGFARTILDGAVM
EGADIDDGLASVRAMVAVARSVENGKTVALADVTGGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=364, Percent_Identity=24.7252747252747, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081947, Length=151, Percent_Identity=25.8278145695364, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082405, Length=91, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24581117, Length=167, Percent_Identity=26.9461077844311, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39236; Mature: 39105

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKQERRLRIGVLGAGQIAQAAHFESCTKAANADLYAICDVAEDLRERMAITHGAEKTY
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCC
GDYDQMLADPDLDAVVIATADAFHVPASLRALQAGKHVLCEKPVGVTIEECLELKAAVDK
CCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCC
SGKVFQVGHMKRFDAGLQAAKSFIRDEMGEMVALKAWYCDSTHRYPMTDAVQPLIVTSAN
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHCCCCEEEECCC
AKKPSTNPKADLRRYYMLAHGCHLIDTARYFAGDIVSVNARLSERAGIWCWFVDVEFASG
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCHHCCCCEEEEEEEEEECCC
TLGHLDLTVQVRMDWHEGFQIYGKNGSILGKTYNPWYYKTSEVDIFREVDGATHRVLGAD
CEEEEEEEEEEEEECCCCEEEECCCCCEEECCCCCCEEECCCEEEEECCCCCCEEEECCC
GHFYRRQVEGFARTILDGAVMEGADIDDGLASVRAMVAVARSVENGKTVALADVTGGV
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
>Mature Secondary Structure 
PAKQERRLRIGVLGAGQIAQAAHFESCTKAANADLYAICDVAEDLRERMAITHGAEKTY
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCC
GDYDQMLADPDLDAVVIATADAFHVPASLRALQAGKHVLCEKPVGVTIEECLELKAAVDK
CCHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCC
SGKVFQVGHMKRFDAGLQAAKSFIRDEMGEMVALKAWYCDSTHRYPMTDAVQPLIVTSAN
CCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHCCCCEEEECCC
AKKPSTNPKADLRRYYMLAHGCHLIDTARYFAGDIVSVNARLSERAGIWCWFVDVEFASG
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCHHCCCCEEEEEEEEEECCC
TLGHLDLTVQVRMDWHEGFQIYGKNGSILGKTYNPWYYKTSEVDIFREVDGATHRVLGAD
CEEEEEEEEEEEEECCCCEEEECCCCCEEECCCCCCEEECCCEEEEECCCCCCEEEECCC
GHFYRRQVEGFARTILDGAVMEGADIDDGLASVRAMVAVARSVENGKTVALADVTGGV
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]