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The map label for this gene is mrdB [H]

Identifier: 115353220

GI number: 115353220

Start: 3504037

End: 3505185

Strand: Direct

Name: mrdB [H]

Synonym: Bamb_3169

Alternate gene names: 115353220

Gene position: 3504037-3505185 (Clockwise)

Preceding gene: 115353219

Following gene: 115353234

Centisome position: 98.52

GC content: 66.06

Gene sequence:

>1149_bases
ATGCAATTCGACAAGCGCGCCTGGCTCGACAAGATCAAGCAGATGTTCGCGGGTTTCGACCGCCCGCTCGCCCTCATCGT
GTTCCTGCTGCTGTGCGTCGGCATCGTCACGCTGTACAGCGCGGCGATCGACATGCCGGGCCGCGTCGAGGACCAATTGC
GCAACATCCTGCTGACGTTCGTGCTGATGTGGGTGATCGCCAACATCCCGCCGACGACGCTGATGCGCTTCGCGGTCCCG
CTATACACGTTCGGGGTCGCGCTGCTAATCGCGGTCGCGCTGTTCGGGATGACCAAGAAAGGCGCGAAGCGCTGGCTGAA
CGTCGGCGTCGTGATCCAGCCGTCCGAAATCCTCAAGATCGCGACACCGCTGATGCTCGCGTGGTACTACCAGCGCCGCG
AAGGCGGGCTGCGCTGGTACGACTTCGTCGTCGCGTTCGGGATCCTGCTCGTGCCGGTCGGCCTGATCGCGAAGCAGCCC
GACCTCGGCACCGGCCTGCTCGTGTTCGCGGCCGGCCTCTTCGTGATCTACCTCGCCGGCCTGTCGTTCAAGCTGATCGT
GCCGGTGCTGGTCGCGGGCGTGATCGCGGTCGGCTCGATCGCCGTGTTCGAGGATCGCATCTGCCAGCCCGAAGTGCAGT
GGCCGCTGATGCACGACTACCAGAAGCACCGCGTGTGCACGCTGCTCGACCCGACCTCCGACCCGCTCGGCAAGGGCTTC
CACACGATCCAGGCCGTGATCGCGATCGGCTCGGGCGGCGCACTCGGCAAGGGCTACCTGAAGGGCACGCAGGCCCACCT
CGAATTCATTCCGGAGAAGCACACCGACTTCATCTTCGCGGTGTTCTCGGAAGAATGGGGGCTCGCCGGCGGCCTCGTGC
TGCTGACGCTGTACATGGCGCTGATCGCGCGCGGGCTCTACATCGCCGCGCAGGGCGCGACGCTGTTCGGCCGGCTGCTC
GCGGGCTCGCTCACGCTCGCGTTCTTCGTCTACGCGTTCGTCAACATCGGGATGGTGAGCGGCGTGCTGCCCGTCGTCGG
CGTGCCGTTGCCGTTCATGAGCTATGGCGGCACCGCGCTGGCGACGCTCGGCGTCGCGATCGGGATGATCATGAGCGTCG
GGCGACAGCGGCGGTTGATGAAGAGCTGA

Upstream 100 bases:

>100_bases
GCGCACAGCCGGTCGCCACCGGGCCGCGCGACGACAACTTCCGTGCCTCGGCCACCGCGAAAGCGGTGAACGCCGGCACC
GCTCATTAACGGAGAAAGGC

Downstream 100 bases:

>100_bases
CGCTGCGGCGTGGCACGCGGCTGCGAGCAGTCGCAGCAATGAAAAACGGCGCCGCGGGCGCCGTTTTTCGTTGGGCAGGC
CGAGTTCAGCCGGCCGCCGT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLIAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFVVAFGILLVPVGLIAKQP
DLGTGLLVFAAGLFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEDRICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGALGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALATLGVAIGMIMSVGRQRRLMKS

Sequences:

>Translated_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLIAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFVVAFGILLVPVGLIAKQP
DLGTGLLVFAAGLFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEDRICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGALGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALATLGVAIGMIMSVGRQRRLMKS
>Mature_382_residues
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTFVLMWVIANIPPTTLMRFAVP
LYTFGVALLIAVALFGMTKKGAKRWLNVGVVIQPSEILKIATPLMLAWYYQRREGGLRWYDFVVAFGILLVPVGLIAKQP
DLGTGLLVFAAGLFVIYLAGLSFKLIVPVLVAGVIAVGSIAVFEDRICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
HTIQAVIAIGSGGALGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMALIARGLYIAAQGATLFGRLL
AGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTALATLGVAIGMIMSVGRQRRLMKS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=382, Percent_Identity=48.1675392670157, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1786277, Length=378, Percent_Identity=30.1587301587302, Blast_Score=156, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41600; Mature: 41600

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVALLIAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGLRWYDFVVAFGILLVPVGLIAKQPDLGTGLLVFAAGLFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
LSFKLIVPVLVAGVIAVGSIAVFEDRICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGALGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMA
HHHHHHHHCCCCCCCCCHHHCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
ATLGVAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFDKRAWLDKIKQMFAGFDRPLALIVFLLLCVGIVTLYSAAIDMPGRVEDQLRNILLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VLMWVIANIPPTTLMRFAVPLYTFGVALLIAVALFGMTKKGAKRWLNVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGLRWYDFVVAFGILLVPVGLIAKQPDLGTGLLVFAAGLFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
LSFKLIVPVLVAGVIAVGSIAVFEDRICQPEVQWPLMHDYQKHRVCTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGALGKGYLKGTQAHLEFIPEKHTDFIFAVFSEEWGLAGGLVLLTLYMA
HHHHHHHHCCCCCCCCCHHHCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LIARGLYIAAQGATLFGRLLAGSLTLAFFVYAFVNIGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
ATLGVAIGMIMSVGRQRRLMKS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]