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The map label for this gene is yahK [H]

Identifier: 115353210

GI number: 115353210

Start: 3492211

End: 3493263

Strand: Direct

Name: yahK [H]

Synonym: Bamb_3159

Alternate gene names: 115353210

Gene position: 3492211-3493263 (Clockwise)

Preceding gene: 115353208

Following gene: 115353216

Centisome position: 98.19

GC content: 66.0

Gene sequence:

>1053_bases
ATGAGCACAACCTACGCTTACGCGGCGACCGATGCGCAATCGCCGCTCGCCCCGTTCGAATTCCAGCGCCGCGCGCTGCG
CGACCTCGACGTCCAGATCGAGGTGCTGTACTGCGGCGTCTGCCACTCGGACCTGCACCAGGCCCGCAACGAATGGCGCA
ACACGATCTATCCGGTCGTGCCGGGCCATGAAATCGTCGGCCGCGTGACCGCAACCGGCCCGCAGGTGTCGCGTTTCAAG
GTCGGCGAGCTGGTCGGCGTCGGCTGTCTCGTCGATTCGTGCCGCACCTGCCCGAGCTGCGCGGAAGGTCTCGAACAGTA
TTGCGAGAACGGCTTCGTCGGCACCTACAACGGCCAGGACCGCGTGACGGGCGACATCACGTACGGCGGCTATTCGACCC
AGCTCGTCGTCGACGAGGCGTTCGTGCTGCGCGTGCCCGAGACGCTGGACCCGGCCGGCGCCGCGCCGCTGCTGTGCGCG
GGGATCACGACCTACTCGCCGCTGCGCCAGTGGAACGTCGGGCCCGGCAAGAAGGTCGGGATCGTCGGCCTCGGCGGGCT
CGGCCACATGGGCGTGAAGCTCGCGCGCGCGATGGGCGCGCACGTCGTGCTGTTCACGACCTCGCCGTCGAAGATCGAGG
ACGGCAAGCGGCTCGGCGCGCACGAAGTGGTGATTTCGAAGGACGAAGCTCAGATGAACGCGCACCTGAACAGCTTCGAC
TTCATCCTGAACACGGTGGCCGCGCAGCACGACCTGAATCCGTTCCTGCACCTGCTGAAGCGCGACGGCACGATGACGCT
CGTCGGCGCGCCGGAGCACGACCATCCGTCGCCGCAGGTGTTCAACCTGATCTTCAAGCGCCGCCGCCTCGCGGGCTCGC
TGATCGGCGGGATCGCGGAAACGCAGGAAATGCTCGATTTCTGCGCGGAGCACGGGATCACGTCGGACATCGAAACGATC
CCGATGCAGCAGATCAATGCCGCTTACGAGCGCATGCTCAAGAGCGACGTGAAGTATCGGTTCGTGGTGGACATGGCGTC
GCTCAAGCAGTAA

Upstream 100 bases:

>100_bases
CGGCTCGCTCCGTACGATGGGCACCTGTCTCGCCGCGTCGCCACATGGCGCGGCGGCAGTCTGTTTCGCCGGATGTTTTC
CCGGACAAGGAGCCCCCTGC

Downstream 100 bases:

>100_bases
CGCAGCAAGCGCTACCCCAAGCGAAACGGGCCGCATGTTCGACATGCGGCCCGTTTTGCATCTGGCTACCGGTCGGCCCG
GCCGCTACGCGCATCGCATC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSTTYAYAATDAQSPLAPFEFQRRALRDLDVQIEVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCPSCAEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQLVVDEAFVLRVPETLDPAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETI
PMQQINAAYERMLKSDVKYRFVVDMASLKQ

Sequences:

>Translated_350_residues
MSTTYAYAATDAQSPLAPFEFQRRALRDLDVQIEVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCPSCAEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQLVVDEAFVLRVPETLDPAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETI
PMQQINAAYERMLKSDVKYRFVVDMASLKQ
>Mature_349_residues
STTYAYAATDAQSPLAPFEFQRRALRDLDVQIEVLYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFKV
GELVGVGCLVDSCRTCPSCAEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQLVVDEAFVLRVPETLDPAGAAPLLCAG
ITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFDF
ILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGITSDIETIP
MQQINAAYERMLKSDVKYRFVVDMASLKQ

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI262073058, Length=367, Percent_Identity=23.433242506812, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI71743840, Length=367, Percent_Identity=23.433242506812, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4501933, Length=363, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=24.1847826086957, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786518, Length=344, Percent_Identity=63.953488372093, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI87082401, Length=345, Percent_Identity=36.5217391304348, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=26.0736196319018, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI226510992, Length=315, Percent_Identity=27.9365079365079, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788073, Length=257, Percent_Identity=27.6264591439689, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082125, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788407, Length=273, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790045, Length=273, Percent_Identity=26.7399267399267, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=336, Percent_Identity=26.4880952380952, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17562584, Length=339, Percent_Identity=27.4336283185841, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17562582, Length=352, Percent_Identity=27.8409090909091, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25146526, Length=329, Percent_Identity=26.4437689969605, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=331, Percent_Identity=26.2839879154079, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=331, Percent_Identity=38.368580060423, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6319949, Length=346, Percent_Identity=34.6820809248555, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=34.1538461538462, Blast_Score=156, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=32.9230769230769, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6319621, Length=324, Percent_Identity=31.4814814814815, Blast_Score=152, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6323729, Length=324, Percent_Identity=30.2469135802469, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319258, Length=314, Percent_Identity=26.1146496815287, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=367, Percent_Identity=25.6130790190736, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737895, Length=376, Percent_Identity=24.468085106383, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38208; Mature: 38077

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTYAYAATDAQSPLAPFEFQRRALRDLDVQIEVLYCGVCHSDLHQARNEWRNTIYPVV
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCPSCAEGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCC
RVTGDITYGGYSTQLVVDEAFVLRVPETLDPAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCEEEEEEEECEEEEECCCCCCCCCCCHHHHHCCCHHCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGITSDIETIPMQQINAAYERMLKSDVKYRFVVDMASLKQ
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCC
>Mature Secondary Structure 
STTYAYAATDAQSPLAPFEFQRRALRDLDVQIEVLYCGVCHSDLHQARNEWRNTIYPVV
CCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCPSCAEGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCC
RVTGDITYGGYSTQLVVDEAFVLRVPETLDPAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCEEEEEEEECEEEEECCCCCCCCCCCHHHHHCCCHHCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGITSDIETIPMQQINAAYERMLKSDVKYRFVVDMASLKQ
HHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]