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The map label for this gene is hslU

Identifier: 115353190

GI number: 115353190

Start: 3456482

End: 3457825

Strand: Direct

Name: hslU

Synonym: Bamb_3139

Alternate gene names: 115353190

Gene position: 3456482-3457825 (Clockwise)

Preceding gene: 115353189

Following gene: 115353193

Centisome position: 97.19

GC content: 64.21

Gene sequence:

>1344_bases
ATGAGCACCATGACCCCTGCCGAGATCGTCTCGGAACTCGACAAGCACATCATTGGTCAGGCCAAGGCGAAGAAGGCCGT
CGCGGTCGCGCTGCGCAACCGCTGGCGCCGCCAGCAGGTCGGCGAGCCGCTGCGTCAGGAAATCACGCCGAAGAACATCC
TGATGATCGGGCCGACGGGCGTCGGCAAGACCGAAATCGCGCGCCGCCTCGCGAAGCTCGCCGATGCGCCGTTCGTCAAG
ATCGAAGCGACCAAGTTCACCGAAGTCGGCTACGTCGGCCGTGACGTCGACAGCATCGTGCGCGACCTGATCGAGATCTC
GGTCAAGCAGACGCGTGAAGCCGAGATGCGCAAGGTGCGCACCAAGGCGACCGACCAGGCGGAAGACCGCATCCTCGACG
TCCTGCTGCCGCAACCGCGCGCGGTCGGCTTCGGCGGCAACGCCGATCACGCGAACGACGACAACAACGCGACGCGCCAG
ACCTTCCGCAAACGCCTGCGCGAAGGCCAGCTCGACGACAAGGAAGTCGAGCTCGACCTCGAGCAGCCGTCGGCCGGCAT
GGACATCATGGCGCCGCCGGGGATGGAAGAGATGACCGAGCAGATCCGCTCGATGTTCTCGAACCTCGGCAGCGGCAAGA
AGCAGCGCCGCAAGGTCAAGATCAAGGAAGCGCTGAAGCTGCTGACCGACGAGGAAGCGGCGAAGATGCTCAACGACGAG
GAAGTGAAGACGAAGGCCGTGCAGAACGTCGAGCAGAACGGCATCGTGTTCCTCGACGAAATCGACAAGATCACGTCGCG
CAACAACGAAGGCAGCGGCGGCGAAGTGTCACGCCAGGGCGTGCAGCGCGACCTGCTGCCGCTCGTCGAGGGCACGACCG
TCAACACGAAGTACGGGATGGTGAAGACCGATCACATCCTGTTCATCGCGAGCGGCGCGTTCCACCTCGCGAAGCCGAGC
GACCTGATCCCCGAACTGCAGGGGCGCTTTCCGATCCGCGTCGAGCTCGACTCGCTGTCGGTTGAAGATTTCGAGGCGAT
CCTCGACGCGACCGACGCGAGCCTCGTCAAGCAGTACCAGGCGCTGCTCGCCACGGAAGACGTGCAGCTCGAGTTCGCCG
CGGACGGCATCCGCCGCCTCGCCGAGATCGCGTATGCGGTCAACGAGAAGACCGAGAACATCGGTGCGCGCCGGCTGTAC
ACGGTGATCGAGAAGCTGCTCGAGGAAGTGTCGTTCTCGGCCGGCAACCACGCCGGCGAGCGCGTGACGATCGACGCGAA
ATATGTCGAGCATGCGCTCGGCGAAGTGTCGCAAGACGAAGACCTGTCGCGCTACGTGCTGTAA

Upstream 100 bases:

>100_bases
CCGCGCGAAATCGTCGAGAAGTCGCTCGAGATCGCCGGCGACATGTGCATCTACACGAACCACAACCGCATCATCGAAAC
GATCGAGTAAGGACCGCACC

Downstream 100 bases:

>100_bases
CGCGCGCGGCGTCGAATGCGAAACGGGCGGCCCGGCGGGCCGCCCGTTTTCGTTGGTGCCGTTGGTGCCGTTGGTGCCGT
TGGTGCCGTTGGTGCGACAC

Product: ATP-dependent protease ATP-binding subunit HslU

Products: NA

Alternate protein names: Unfoldase HslU [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSTMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVGEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFVK
IEATKFTEVGYVGRDVDSIVRDLIEISVKQTREAEMRKVRTKATDQAEDRILDVLLPQPRAVGFGGNADHANDDNNATRQ
TFRKRLREGQLDDKEVELDLEQPSAGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNDE
EVKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGMVKTDHILFIASGAFHLAKPS
DLIPELQGRFPIRVELDSLSVEDFEAILDATDASLVKQYQALLATEDVQLEFAADGIRRLAEIAYAVNEKTENIGARRLY
TVIEKLLEEVSFSAGNHAGERVTIDAKYVEHALGEVSQDEDLSRYVL

Sequences:

>Translated_447_residues
MSTMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVGEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFVK
IEATKFTEVGYVGRDVDSIVRDLIEISVKQTREAEMRKVRTKATDQAEDRILDVLLPQPRAVGFGGNADHANDDNNATRQ
TFRKRLREGQLDDKEVELDLEQPSAGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNDE
EVKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGMVKTDHILFIASGAFHLAKPS
DLIPELQGRFPIRVELDSLSVEDFEAILDATDASLVKQYQALLATEDVQLEFAADGIRRLAEIAYAVNEKTENIGARRLY
TVIEKLLEEVSFSAGNHAGERVTIDAKYVEHALGEVSQDEDLSRYVL
>Mature_446_residues
STMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVGEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFVKI
EATKFTEVGYVGRDVDSIVRDLIEISVKQTREAEMRKVRTKATDQAEDRILDVLLPQPRAVGFGGNADHANDDNNATRQT
FRKRLREGQLDDKEVELDLEQPSAGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNDEE
VKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGMVKTDHILFIASGAFHLAKPSD
LIPELQGRFPIRVELDSLSVEDFEAILDATDASLVKQYQALLATEDVQLEFAADGIRRLAEIAYAVNEKTENIGARRLYT
VIEKLLEEVSFSAGNHAGERVTIDAKYVEHALGEVSQDEDLSRYVL

Specific function: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N

COG id: COG1220

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family. HslU subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790366, Length=447, Percent_Identity=64.6532438478747, Blast_Score=584, Evalue=1e-168,
Organism=Escherichia coli, GI1786642, Length=102, Percent_Identity=48.0392156862745, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR019489
- InterPro:   IPR004491 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 49761; Mature: 49630

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVGEPLRQEITPKNILMIGPTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCC
VGKTEIARRLAKLADAPFVKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTREAEMRKVR
CCHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKATDQAEDRILDVLLPQPRAVGFGGNADHANDDNNATRQTFRKRLREGQLDDKEVELDL
HHHCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEC
EQPSAGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNDE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGM
HHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCC
VKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVEDFEAILDATDASLVKQYQ
EEECEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALLATEDVQLEFAADGIRRLAEIAYAVNEKTENIGARRLYTVIEKLLEEVSFSAGNHAGE
HHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RVTIDAKYVEHALGEVSQDEDLSRYVL
EEEEEHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure 
STMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVGEPLRQEITPKNILMIGPTG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCC
VGKTEIARRLAKLADAPFVKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTREAEMRKVR
CCHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKATDQAEDRILDVLLPQPRAVGFGGNADHANDDNNATRQTFRKRLREGQLDDKEVELDL
HHHCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEC
EQPSAGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNDE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCHH
EVKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGM
HHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCC
VKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVEDFEAILDATDASLVKQYQ
EEECEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALLATEDVQLEFAADGIRRLAEIAYAVNEKTENIGARRLYTVIEKLLEEVSFSAGNHAGE
HHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RVTIDAKYVEHALGEVSQDEDLSRYVL
EEEEEHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA