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The map label for this gene is yhdG [H]

Identifier: 115353152

GI number: 115353152

Start: 3422279

End: 3423679

Strand: Direct

Name: yhdG [H]

Synonym: Bamb_3101

Alternate gene names: 115353152

Gene position: 3422279-3423679 (Clockwise)

Preceding gene: 115353151

Following gene: 115353153

Centisome position: 96.22

GC content: 67.52

Gene sequence:

>1401_bases
ATGTCCCTCTTCCGCAAGAAAAACGTCGATCGCATGATCGCCGGCGCGCATGGCGCCGGGCTCAAGAAAGCGCTCGGCGC
AATCGACCTCACCTTCCTCGGCATCGGCGCGATCATCGGCACCGGGATCTTCGTGCTGACCGGCACCGGCGCCGTTCAGG
CCGGCCCGGCGCTGATGCTGTCGTTCGTGATCGCGGCGATCGCGTGCGGCCTCGCGGCGCTGTCGTACGCCGAATTCGCG
TCGACGATTCCGGTCGCGGGCTCGATCTACACGTACTCGTACGCGACGCTCGGCGAGCTCGTCGCATGGATCATCGGCTG
GGACCTGATGCTCGAATACGGCCTCGCGGCGTCGGCCGTGTCGGTCGGCTGGTCGGGCTACCTGCAGTCGCTGCTGCAGG
GCTTCGGGCTCGCGCTGCCGACCGTGCTGACGGCCGCGCCCGGCGCGATCCCCGACGTCGTCACGTGGTTCAACCTGCCC
GCGTTCCTCGTGATGCTGGTGATCACGACGCTGCTGTCGATCGGCATCCGCGAGTCGACCCGCATCAACAACATCATGGT
GTTCATCAAGGTGTCGGTGGTGCTGCTCGTGATCGCGGTCGGCCTGTTCCACGTGACGCCCGCGAACTGGAAACCGTTCA
TGCCGCACGGCTGGAACGGCGTGTTCGGCGCGGCCGCGGTGATGTTCTTCGCGTTCATCGGCTTCGACGCGGTGTCGTCG
GCGGCCGAGGAAGTGAAGAATCCGAAGCGCGACCTGCCGATCGGCATCATCGCGTCGCTCGCCGTGTGCGCGGTGCTGTA
CGTGACGGTCGCGGCGGTCGCGACCGGCATCGTGCCGGCGGCCCAGTACGCGAACGTGTCGCACCCGATCTCGTATGCGC
TGCAGATCGCCGGCGAGAAGTGGGTCGCGGGCTTCATCGATCTTGGCGCGGTGCTCGGCATGCTGACCGTGATCCTCGTG
ATGAGCTACGGCCAGACGCGGATCATCTTCGCGATGTCGCGCGACGGGCTGCTGCCGGCGATGCTGTCGCGCGTGCATCC
GCGCTTCGCGACGCCGTTCCTGACGACCTGGCTCGTCGGCCTGTTCTTCGGGCTGATCGCCGCGCTCGTGCCGCTGAACG
TGCTCGCCGAGCTGATCAACATCGGCACGCTCGCCGCGTTCTCGATGGTGTCGATCGCGGTGCTGGTGCTGCGCCGCACG
CATCCGGAGCTGCCGCGCGCGTTCCGCTGCCCGGGCGTGCCGGTGGTGCCGATCCTCGCGGTCGCCGCGTGCCTGTTCCT
GATGCTGAACCTGCAGCCCGTCACGTGGGCCGCGTTCGGCATCTGGCTCGTGATCGGCCTCGTGATCTACTTCCTGTATT
CGCGTCACCACTCGAAGCTCGCCCGCGGCCACGCGGACTGA

Upstream 100 bases:

>100_bases
GCATCGCAGCAGGTCTTGCGCGCCAAATCGGCTAAAATTGCGGGTTTTCCTTCTCTCACTCGGCGCCGCCGCGTTCGCGC
GCGCTGGAGACTCATCCGCA

Downstream 100 bases:

>100_bases
CATCCGGCCGCGACGCGCCGCGTCGCTCCGCTGCAACGGCGCACCCGCCTCGCGGGCGCGCCGTTTGCGTTTGTGGGGCG
GCGGGCAGCGTGTGCGGGCA

Product: amino acid permease-associated protein

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSLFRKKNVDRMIAGAHGAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGLALPTVLTAAPGAIPDVVTWFNLP
AFLVMLVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPAAQYANVSHPISYALQIAGEKWVAGFIDLGAVLGMLTVILV
MSYGQTRIIFAMSRDGLLPAMLSRVHPRFATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPELPRAFRCPGVPVVPILAVAACLFLMLNLQPVTWAAFGIWLVIGLVIYFLYSRHHSKLARGHAD

Sequences:

>Translated_466_residues
MSLFRKKNVDRMIAGAHGAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGLALPTVLTAAPGAIPDVVTWFNLP
AFLVMLVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPAAQYANVSHPISYALQIAGEKWVAGFIDLGAVLGMLTVILV
MSYGQTRIIFAMSRDGLLPAMLSRVHPRFATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPELPRAFRCPGVPVVPILAVAACLFLMLNLQPVTWAAFGIWLVIGLVIYFLYSRHHSKLARGHAD
>Mature_465_residues
SLFRKKNVDRMIAGAHGAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFAS
TIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAVSVGWSGYLQSLLQGFGLALPTVLTAAPGAIPDVVTWFNLPA
FLVMLVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSSA
AEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPAAQYANVSHPISYALQIAGEKWVAGFIDLGAVLGMLTVILVM
SYGQTRIIFAMSRDGLLPAMLSRVHPRFATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRTH
PELPRAFRCPGVPVVPILAVAACLFLMLNLQPVTWAAFGIWLVIGLVIYFLYSRHHSKLARGHAD

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=439, Percent_Identity=35.5353075170843, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=34.5070422535211, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI258614005, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI258614003, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI181337167, Length=418, Percent_Identity=34.688995215311, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI110347453, Length=385, Percent_Identity=35.5844155844156, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI114326544, Length=433, Percent_Identity=32.5635103926097, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI114326550, Length=433, Percent_Identity=32.5635103926097, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI187423910, Length=493, Percent_Identity=26.5720081135903, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI7657591, Length=493, Percent_Identity=26.5720081135903, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI33286428, Length=482, Percent_Identity=25.5186721991701, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI115648063, Length=407, Percent_Identity=24.8157248157248, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI115648022, Length=407, Percent_Identity=24.8157248157248, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI186910308, Length=413, Percent_Identity=25.6658595641646, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI186910306, Length=413, Percent_Identity=25.6658595641646, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI186910304, Length=413, Percent_Identity=25.6658595641646, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7657683, Length=402, Percent_Identity=25.3731343283582, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI71979932, Length=449, Percent_Identity=25.3897550111359, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI9790235, Length=299, Percent_Identity=24.0802675585284, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786302, Length=477, Percent_Identity=24.1090146750524, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082023, Length=450, Percent_Identity=23.5555555555556, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786602, Length=476, Percent_Identity=24.1596638655462, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786789, Length=354, Percent_Identity=22.8813559322034, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081915, Length=431, Percent_Identity=24.3619489559165, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87081869, Length=464, Percent_Identity=22.8448275862069, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788480, Length=460, Percent_Identity=24.1304347826087, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081708, Length=488, Percent_Identity=21.9262295081967, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786694, Length=403, Percent_Identity=24.317617866005, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367353, Length=471, Percent_Identity=23.9915074309979, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87082250, Length=421, Percent_Identity=23.9904988123515, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789017, Length=360, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790653, Length=420, Percent_Identity=22.1428571428571, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786908, Length=328, Percent_Identity=22.2560975609756, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=36.1650485436893, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17533459, Length=411, Percent_Identity=34.3065693430657, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI17531343, Length=408, Percent_Identity=34.0686274509804, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17540018, Length=433, Percent_Identity=25.8660508083141, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17568033, Length=427, Percent_Identity=24.5901639344262, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=374, Percent_Identity=25.9358288770053, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193208714, Length=428, Percent_Identity=26.4018691588785, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32566695, Length=428, Percent_Identity=26.4018691588785, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537453, Length=331, Percent_Identity=25.3776435045317, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=443, Percent_Identity=22.1218961625282, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=443, Percent_Identity=22.1218961625282, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319991, Length=356, Percent_Identity=26.9662921348315, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=38.4057971014493, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=38.4057971014493, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24667468, Length=408, Percent_Identity=36.0294117647059, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24668806, Length=431, Percent_Identity=34.8027842227378, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI21356285, Length=431, Percent_Identity=34.8027842227378, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24668802, Length=431, Percent_Identity=34.8027842227378, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI161077963, Length=428, Percent_Identity=35.5140186915888, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI281366235, Length=413, Percent_Identity=34.8668280871671, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI116007820, Length=413, Percent_Identity=34.8668280871671, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=34.6246973365617, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=34.6246973365617, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI21357367, Length=426, Percent_Identity=27.9342723004695, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI221331183, Length=474, Percent_Identity=24.2616033755274, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17647653, Length=474, Percent_Identity=24.2616033755274, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24664379, Length=474, Percent_Identity=24.2616033755274, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24651635, Length=425, Percent_Identity=24.4705882352941, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24651633, Length=425, Percent_Identity=24.4705882352941, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45550968, Length=466, Percent_Identity=22.7467811158798, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19921172, Length=466, Percent_Identity=22.7467811158798, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24641993, Length=410, Percent_Identity=26.0975609756098, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641995, Length=410, Percent_Identity=25.609756097561, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49369; Mature: 49237

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFRKKNVDRMIAGAHGAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH
SFVIAAIACGLAALSYAEFASTIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLAASAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGWSGYLQSLLQGFGLALPTVLTAAPGAIPDVVTWFNLPAFLVMLVITTLLSIGIREST
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
RINNIMVFIKVSVVLLVIAVGLFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPAAQYANVSHPISYALQIAGEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHH
WVAGFIDLGAVLGMLTVILVMSYGQTRIIFAMSRDGLLPAMLSRVHPRFATPFLTTWLVG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCHHCHHHHHHHHHH
LFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRTHPELPRAFRCPGVPVVPILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHH
VAACLFLMLNLQPVTWAAFGIWLVIGLVIYFLYSRHHSKLARGHAD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLFRKKNVDRMIAGAHGAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]