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The map label for this gene is glmS [H]

Identifier: 115353080

GI number: 115353080

Start: 3348216

End: 3350033

Strand: Direct

Name: glmS [H]

Synonym: Bamb_3029

Alternate gene names: 115353080

Gene position: 3348216-3350033 (Clockwise)

Preceding gene: 115353079

Following gene: 115353081

Centisome position: 94.14

GC content: 67.38

Gene sequence:

>1818_bases
ATGTGCGGCATTGTCGGCGCAGTTGCGCAGCGTAATATCGTTCCGGTGCTGATCGAAGGATTGCGGCGCCTCGAATACCG
TGGCTACGATTCGTGCGGTGTCGCCGTGCTCGAGCCAGGCGCACCGAAGCGCGCGCGCAGCGTCGCGCGCGTCGCCGATC
TCGACGCGCAGGTCCACGAATCGCACCTCGAAGGCACGACCGGCGTCGCGCACACGCGCTGGGCCACGCACGGCGCGCCC
GTCACGCACAACGCGCACCCGATCTTCTCGTCGAACGCGCTCGCGCTGGTGCACAACGGCATCATCGAGAACTTCGAGAC
GCTGCGCGAAACACTGCGTGCGAAGGGCTACGAATTCGTGTCGCAGACCGACACTGAAGTGATCGCGCACCTCGTGCACA
GCCTGTATCGCGGCAACCTGTTCGACGCCGTGCGCGAAGCCGTGCAGCAGCTGCACGGCGCGTATGCGATCGCGGTCACC
CACAAGGACGAGCCGCACACGGTCGTCGGTGCGCGCCAGGGTTCGCCGCTCGTCGTCGGTCACGGCGACGGCGAGAACTT
CCTCGCGTCCGACGCGCTGGCGCTGGCCGGCAGCACCGACCGCTTCACGTTCCTCGAGGAAGGCGACGTGTGCGAACTGT
CGCTCGACGGCGTGAAGATCGTCGACCGCCACGGCGCGCTCGCGCAGCGCGAGATCCGCGTCGTCAGCGCATACGGCGGC
GCGGTCGAGCTGGGCCCGTATCGCCACTTCATGCAGAAGGAAATCTTCGAGCAGCCGCGCGCGATCGGCGACACGGTGCC
GCAAACCGACGCGTTCGACGCGACGCTGTTCGGCGACGCGGCCCCCGCCGCGTTCGCTAACGTTGACAGCCTGCTGATCC
TCGCGTGCGGCACGAGCTACTACTCGGGCCTCACCGCGAAGTACTGGCTCGAATCGATCGCGAAGATCCCGACCCAGGTC
GAGATCGCGAGCGAATACCGCTACCGCGAATCGGTGCCGAACCCGCGCCAGCTCGTGCTGGTGATCTCGCAATCGGGCGA
GACGGCCGACACGCTCGCCGCGCTCAAGCACGCGCAGTCGCTCGGCCACACGCATACGCTCGCGGTGTGCAACGTCGCGA
CGAGCGCGATGGTGCGCCTCACCGAGATGCAGTTCCTGACGCACGCGGGCACCGAGATCGGCGTCGCGTCGACGAAGGCG
TTCACGACCCAGCTCGTCGCGCTGTTCGTGCTGGCCGCGACGCTCGGCAAGCTGCGCGGGCACGTCGATGCCGCGCAGGA
AGCGGAATTCCTGAAGCAGCTGCGCCACCTGCCGGCCGCGCTGAACAGCGTGCTCGCGCTCGAGCCGCAGATCATCGCGT
GGTCGGAGGAATTCGCACGCAAGGAAAACGCGCTGTTCCTCGGCCGCGGGCTGCACTACCCGATCGCGCTCGAAGGCGCG
CTGAAGCTGAAGGAAATCTCGTACATCCACGCGGAGGCCTATCCGGCCGGCGAACTGAAGCACGGGCCGCTCGCGCTCGT
CACGGAAGCGATGCCGGTCGTCACGGTCGCGCCGAACGACACGCTGCTCGAGAAGCTGAAGTCGAACATGCAGGAAGTGC
GTGCGCGCGGCGGCGAGCTGTACGTGTTCGCGGATGCCGACACGCAGATCGTCAACGACGACGGCCTGCACGTGATCCGG
ATGCCGGAACACTACGGGCAGCTGTCGCCGATCCTGCATGTGGTGCCGCTGCAGCTGCTCGCGTATCACACCGCGTGCGC
GCGCGGCACCGATGTGGACAAGCCGCGCAACCTCGCGAAGTCGGTGACGGTGGAGTAA

Upstream 100 bases:

>100_bases
CGCAGACCGCGAAGAGCGGCTACGTCCGCCCGGTCAAGAAGAAAAGTTGACATCACGCGGGCGCCCCACGGCGCCCGTTT
CCACATAGAGGGTAAGTTTC

Downstream 100 bases:

>100_bases
CGCAGGTTCCCCGGACGGGCTGTCGTTGCCCGTCCGGGCCGCATATCGGTAGGAAGCAGCGCACGAAGCAGGCCATTCGG
CCAGGTCGAAATATGTACCA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVHESHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFETLRETLRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVT
HKDEPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFANVDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVHESHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFETLRETLRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVT
HKDEPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFANVDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVHESHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFETLRETLRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVT
HKDEPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFANVDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=36.3503649635037, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=35.6204379562044, Blast_Score=380, Evalue=1e-105,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=55.1554828150573, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=228, Percent_Identity=28.0701754385965, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=431, Percent_Identity=39.2111368909513, Blast_Score=279, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17532897, Length=439, Percent_Identity=37.129840546697, Blast_Score=271, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17532899, Length=439, Percent_Identity=37.129840546697, Blast_Score=271, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6322745, Length=449, Percent_Identity=36.5256124721604, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=29.3981481481481, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=36.7647058823529, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=35.7664233576642, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28573187, Length=256, Percent_Identity=28.515625, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24659598, Length=256, Percent_Identity=26.5625, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65505; Mature: 65505

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVHE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
SHLEGTTGVAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFETLRETLRAKGYEFV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVTHKDEPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
CCCCCCHHHHCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCHHHHHEEEEEECCC
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFANVDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEECCCCCCHHHHCCCEEEEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQS
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNDDGLHVIRMPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVHE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
SHLEGTTGVAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFETLRETLRAKGYEFV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGNLFDAVREAVQQLHGAYAIAVTHKDEPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRHGALAQREIRVVSAYGG
CCCCCCHHHHCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCHHHHHEEEEEECCC
AVELGPYRHFMQKEIFEQPRAIGDTVPQTDAFDATLFGDAAPAAFANVDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEECCCCCCHHHHCCCEEEEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQS
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNDDGLHVIRMPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]