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The map label for this gene is gylR [H]

Identifier: 115353013

GI number: 115353013

Start: 3265302

End: 3266177

Strand: Direct

Name: gylR [H]

Synonym: Bamb_2962

Alternate gene names: 115353013

Gene position: 3265302-3266177 (Clockwise)

Preceding gene: 115353006

Following gene: 115353014

Centisome position: 91.81

GC content: 70.32

Gene sequence:

>876_bases
ATGCCCGCCAACCCGCTTCCCGACGACGATCTCGCTGATTCCGACACCGACGACACCGGCTCCGGCGAGCATGGCGAAGG
CGGCGAGAAGGTCCGCTCCGGCATCCAGTCGATCGAGGTCGGCTTTCGCCTGCTCGAGGTGCTGACGAGCGAGCCGCGCG
CGATGATGCTGCGCGATCTCGCGCAGCGCGCGGGCATGAGCCCTGCGAAGGCGCACCGCTACCTGGTGAGCTTCTCGCGG
CTCGGTGTCGTGTCGCAGGATCCCGTGTCGGGCCGCTACGAACTCGGCGGCTTCGCGCTGCAGATGGGCCTCGCGCGGCT
CGCGCGCGTGGACGGCGTGAAGCTCGCGCGCATCGCGCTGACCGAGTTGCGCGACCGCGTCGACCAGACGGTCGGCATCG
CGGTGTGGGGCAATCAGGGCCCGACGATCGTGCACTGGATGGAGTCGAGCCACCCCGCGAAGGCGTCGCTGAAGCTCGGC
GACGTGATGCCGCTGCTCGGCTCCGCGACGGGCCTGCTGTTCGCCGCGTACCTGCCGCGCAGCAAGACCGCGGCGATGCT
CGAACGCGAACTCGCCGATACGCGCCGCTCGCCGCATCACGGCGGCCCGCGCACGCTCGAGGAAGTCGACGCGGTGCTCG
CCGACGTGCGCGCGCATCAGGCCGCGCGCGTCGAAGGGATGCTGCTGCCGACGATCCACGCGTTCTGCATGCCGGTGTTC
GATGCGGTCGGCGAACTGGCGCTCGCGATCGTCGCGCTCGGTCAGGAAGGCACGTTCGACATCGCGTGGGGCGGCGAGAT
GGACACCGCGCTGCGCGCGTGCGCGCAGAAACTGTCTTACGAACTCGGCTATAGTCCGGACGCGCGCGACGCCTGA

Upstream 100 bases:

>100_bases
GAGGGAATCTATTTTACGATGGTGAATCCGCGCGGCGCGCCACGATCGTGCGTGCCGCTTTCGTCCCGACCCTTGCCGCT
TCGCCGCGCCCCCGTTGCCC

Downstream 100 bases:

>100_bases
CACGCGACGCGCGCGACACCCGGACGAATGCGCGCGATGCAGCGCGAACGCGCGGCGCGGCCGGCGGTCCGATGGGTGTG
ACGTGCGATCGTGATGTGCC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MPANPLPDDDLADSDTDDTGSGEHGEGGEKVRSGIQSIEVGFRLLEVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFSR
LGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTELRDRVDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLG
DVMPLLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLEEVDAVLADVRAHQAARVEGMLLPTIHAFCMPVF
DAVGELALAIVALGQEGTFDIAWGGEMDTALRACAQKLSYELGYSPDARDA

Sequences:

>Translated_291_residues
MPANPLPDDDLADSDTDDTGSGEHGEGGEKVRSGIQSIEVGFRLLEVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFSR
LGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTELRDRVDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLG
DVMPLLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLEEVDAVLADVRAHQAARVEGMLLPTIHAFCMPVF
DAVGELALAIVALGQEGTFDIAWGGEMDTALRACAQKLSYELGYSPDARDA
>Mature_290_residues
PANPLPDDDLADSDTDDTGSGEHGEGGEKVRSGIQSIEVGFRLLEVLTSEPRAMMLRDLAQRAGMSPAKAHRYLVSFSRL
GVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIALTELRDRVDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGD
VMPLLGSATGLLFAAYLPRSKTAAMLERELADTRRSPHHGGPRTLEEVDAVLADVRAHQAARVEGMLLPTIHAFCMPVFD
AVGELALAIVALGQEGTFDIAWGGEMDTALRACAQKLSYELGYSPDARDA

Specific function: May be an activator protein for the gylABX operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789999, Length=279, Percent_Identity=26.5232974910394, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788131, Length=254, Percent_Identity=24.4094488188976, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786468, Length=154, Percent_Identity=25.3246753246753, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082359, Length=158, Percent_Identity=25.9493670886076, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31196; Mature: 31065

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPANPLPDDDLADSDTDDTGSGEHGEGGEKVRSGIQSIEVGFRLLEVLTSEPRAMMLRDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AQRAGMSPAKAHRYLVSFSRLGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIAL
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
TELRDRVDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLLFAAYLPR
HHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
SKTAAMLERELADTRRSPHHGGPRTLEEVDAVLADVRAHQAARVEGMLLPTIHAFCMPVF
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DAVGELALAIVALGQEGTFDIAWGGEMDTALRACAQKLSYELGYSPDARDA
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PANPLPDDDLADSDTDDTGSGEHGEGGEKVRSGIQSIEVGFRLLEVLTSEPRAMMLRDL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AQRAGMSPAKAHRYLVSFSRLGVVSQDPVSGRYELGGFALQMGLARLARVDGVKLARIAL
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
TELRDRVDQTVGIAVWGNQGPTIVHWMESSHPAKASLKLGDVMPLLGSATGLLFAAYLPR
HHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCC
SKTAAMLERELADTRRSPHHGGPRTLEEVDAVLADVRAHQAARVEGMLLPTIHAFCMPVF
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DAVGELALAIVALGQEGTFDIAWGGEMDTALRACAQKLSYELGYSPDARDA
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3225846; 12000953 [H]