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The map label for this gene is ggt [H]

Identifier: 115352987

GI number: 115352987

Start: 3239019

End: 3240899

Strand: Direct

Name: ggt [H]

Synonym: Bamb_2936

Alternate gene names: 115352987

Gene position: 3239019-3240899 (Clockwise)

Preceding gene: 115352986

Following gene: 115352991

Centisome position: 91.07

GC content: 71.03

Gene sequence:

>1881_bases
ATGTTCGATCGGATTCGTCCGCATTCGCGTCCCTGGACGCTCGCCGCCGCAGTCGCATTCGCACTCGTCGCCTTCGGTGC
CGGCTGCACGTCACCGTCCGCGCCGTCGGGCGCCGTCGTCCCGGTCGCCGCCGCATCGGGCGCCGCCGTGCCGCTGCCCG
GCGTTCACTCCCCCGAACTGTCGTCGGGCTGGACCGACAAGCCGGGCTGGACCTCGCAGCACGCGATGATCGCGGCCGCG
AACCCGCTCGCGACGCAGGCCGGCTACGACATGCTGAAGGCCGGCGGCACCGCGATCGACGCGGCGATCGCGACGCAGAT
GGTGCTCGCGCTCGTCGAGCCGCAATCGTCGGGCATCGGCGGCGGCGCGTTCATGCTGTATTTCGACGGCCACGCGACGC
AGGCGTACGACGGCCGCGAGACCGCGCCGGCCGCCGCCACCGAGCGCCTGTTCTACGGGCCGACCGGCCAGCCGATGCGC
TTCTACGAAGGTGTCGTCGGCGGGCGCTCGGTCGGCACGCCGGGCGTGCTGCGGATGCTCGACGCCGCGCATCGCGCGCA
CGGCAAGCTGCCGTGGCGCCGGCTGTTCCAGCCCGCGATCCGGCTCGCCGAGCACGGCTTCACGATCAGCCCGCGGCTGG
CGATGCTGATCGCGAACGACAAGTACCTGATGAACGACCCGGCCGCGCGCGCGTACTTCTACAACGACGACGGCACGCCG
AAGGCGGCCGGCACCGTGCTGAAGAACCCCGCGCTCGCGACCGTGCTGCGCCAGGTCGCCGACCGCGGCGCGAACGCGTT
CTACACCGGCGCGATCGCGCGCGACATCGTCGCGAAGGTGCGCAAGCACCCGACCAATCCGGGTCTGCTGTCGCTGCAGG
ATCTCGCGCGCTACAAGGCGAAGGTGCGTGCGCCGCTGTGTACCGACTACCGGCGCTCGGTGGTGTGCGGGATGCCGCCG
CCGTCGTCGGGCGGCCTCGCGATCGCGCAGATGCTCGGCATCCTGGAGACGATGCCCGACTGGCAGCAGATCGGCGCGCA
GAAGCCGGTGCGCAACGAGGTCGGCTACGAGCCGACGCCGTTCGCCGCGCATCTGTTCAGCGAGGCCGGCCGCCTCGCGT
TCGCGGACCGCGCGCGCTACGTCGCCGATCCCGATTTCGCGCCGCTGCCGGGCGGCAGTTGGGCGAGCCTCACCGACAAG
GCCTACCTCGCGCAGCGTGCGCGCCTGATCGGCGACAACAGCATGGGCGTCGCGCAGGCCGGCACGCCGCAGGGCGCGGC
GCTCGCGCTGGCCGACGACCGCAGCCCCGAATTGCCGTCGACCTCCGACATCGCGATCGTCGACCGCTACGGTCAGGCGC
TGTCGATGACGACCAGCGTCGAGGACGCGTTCGGTTCGCGGCTGATGGTGCGCGGCTTCATGCTGAACAACCAGCTCACC
GATTTCTCGTTCGTGTCGAGCGAGAACGGCCGGCCGGTCGCGAACCGTGTGCAACCCGGCAAGCGGCCGCGCTCGGCGAT
GTCGCCGGAGCTCGTGTTCGACCAGAAGACGAAGCAGGTGACGATGATCGTCGGCTCGGCCGGCGGCCCCGCGATCATCA
ACCACGTCGCGAAAACGCTGATCGGCGTGCTCGACTGGGGGATGACGATGCAGCAGGCGATCGCGCTGCCGAACGTCGGG
TCGACGAACGGACCGACGCAGCTCGAGCGCGGCCGCGTGTCGGACGCGCTCGTCGACGGGCTGAAGGGACGTGGGCACGA
CGTGCAGGTCGTCGAGTTGAACTCGGGACTGCAGGGGATCCAGCGGCTGAACCTGCAGGGTCAGACGGTGTGGTTCGGCG
GCGCGGATCCGCGGCGCGAAGGAGTCGCGATGGGGGATTGA

Upstream 100 bases:

>100_bases
GACAATCCGCCGCCCGCACGGCGACAATAGCGCGCCGCCCGTGCGGAGCGCGTGCCGCGCACACGCCGCCGCCTTCGAAT
TCACCGTTGCCGAGGGTTCA

Downstream 100 bases:

>100_bases
GGCTGCGGAAGCGGTGCGGCCCGCGCATGCGGTATCAGACTGGCAACCTTGCTCATGCCGAAAATGGCCATGCCCAGACA
GGGTGAACAAGATACGCTCC

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MFDRIRPHSRPWTLAAAVAFALVAFGAGCTSPSAPSGAVVPVAAASGAAVPLPGVHSPELSSGWTDKPGWTSQHAMIAAA
NPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGGAFMLYFDGHATQAYDGRETAPAAATERLFYGPTGQPMR
FYEGVVGGRSVGTPGVLRMLDAAHRAHGKLPWRRLFQPAIRLAEHGFTISPRLAMLIANDKYLMNDPAARAYFYNDDGTP
KAAGTVLKNPALATVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSLQDLARYKAKVRAPLCTDYRRSVVCGMPP
PSSGGLAIAQMLGILETMPDWQQIGAQKPVRNEVGYEPTPFAAHLFSEAGRLAFADRARYVADPDFAPLPGGSWASLTDK
AYLAQRARLIGDNSMGVAQAGTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSVEDAFGSRLMVRGFMLNNQLT
DFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDQKTKQVTMIVGSAGGPAIINHVAKTLIGVLDWGMTMQQAIALPNVG
STNGPTQLERGRVSDALVDGLKGRGHDVQVVELNSGLQGIQRLNLQGQTVWFGGADPRREGVAMGD

Sequences:

>Translated_626_residues
MFDRIRPHSRPWTLAAAVAFALVAFGAGCTSPSAPSGAVVPVAAASGAAVPLPGVHSPELSSGWTDKPGWTSQHAMIAAA
NPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGGAFMLYFDGHATQAYDGRETAPAAATERLFYGPTGQPMR
FYEGVVGGRSVGTPGVLRMLDAAHRAHGKLPWRRLFQPAIRLAEHGFTISPRLAMLIANDKYLMNDPAARAYFYNDDGTP
KAAGTVLKNPALATVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSLQDLARYKAKVRAPLCTDYRRSVVCGMPP
PSSGGLAIAQMLGILETMPDWQQIGAQKPVRNEVGYEPTPFAAHLFSEAGRLAFADRARYVADPDFAPLPGGSWASLTDK
AYLAQRARLIGDNSMGVAQAGTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSVEDAFGSRLMVRGFMLNNQLT
DFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDQKTKQVTMIVGSAGGPAIINHVAKTLIGVLDWGMTMQQAIALPNVG
STNGPTQLERGRVSDALVDGLKGRGHDVQVVELNSGLQGIQRLNLQGQTVWFGGADPRREGVAMGD
>Mature_626_residues
MFDRIRPHSRPWTLAAAVAFALVAFGAGCTSPSAPSGAVVPVAAASGAAVPLPGVHSPELSSGWTDKPGWTSQHAMIAAA
NPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGGAFMLYFDGHATQAYDGRETAPAAATERLFYGPTGQPMR
FYEGVVGGRSVGTPGVLRMLDAAHRAHGKLPWRRLFQPAIRLAEHGFTISPRLAMLIANDKYLMNDPAARAYFYNDDGTP
KAAGTVLKNPALATVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSLQDLARYKAKVRAPLCTDYRRSVVCGMPP
PSSGGLAIAQMLGILETMPDWQQIGAQKPVRNEVGYEPTPFAAHLFSEAGRLAFADRARYVADPDFAPLPGGSWASLTDK
AYLAQRARLIGDNSMGVAQAGTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSVEDAFGSRLMVRGFMLNNQLT
DFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDQKTKQVTMIVGSAGGPAIINHVAKTLIGVLDWGMTMQQAIALPNVG
STNGPTQLERGRVSDALVDGLKGRGHDVQVVELNSGLQGIQRLNLQGQTVWFGGADPRREGVAMGD

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=558, Percent_Identity=29.7491039426523, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI73915090, Length=558, Percent_Identity=29.7491039426523, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI73915096, Length=558, Percent_Identity=29.7491039426523, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI73915094, Length=558, Percent_Identity=29.7491039426523, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI113429324, Length=527, Percent_Identity=29.6015180265655, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI113429326, Length=532, Percent_Identity=29.3233082706767, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI153266885, Length=569, Percent_Identity=28.1195079086116, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI153266901, Length=570, Percent_Identity=27.719298245614, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI109148539, Length=530, Percent_Identity=27.3584905660377, Blast_Score=136, Evalue=8e-32,
Organism=Homo sapiens, GI153266907, Length=567, Percent_Identity=27.1604938271605, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI30581157, Length=195, Percent_Identity=31.7948717948718, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI30581155, Length=195, Percent_Identity=31.7948717948718, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI171543825, Length=215, Percent_Identity=30.6976744186047, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789856, Length=562, Percent_Identity=33.6298932384342, Blast_Score=261, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI72000294, Length=569, Percent_Identity=29.5254833040422, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI212646519, Length=569, Percent_Identity=29.5254833040422, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI193208245, Length=520, Percent_Identity=31.1538461538462, Blast_Score=205, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI193208247, Length=520, Percent_Identity=31.1538461538462, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17542894, Length=566, Percent_Identity=28.9752650176678, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17506189, Length=564, Percent_Identity=27.4822695035461, Blast_Score=165, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI72001497, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72001495, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323330, Length=553, Percent_Identity=25.8589511754069, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859893, Length=557, Percent_Identity=30.3411131059246, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI45551474, Length=565, Percent_Identity=29.5575221238938, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24642670, Length=565, Percent_Identity=29.5575221238938, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24642666, Length=565, Percent_Identity=29.5575221238938, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI161077880, Length=565, Percent_Identity=29.5575221238938, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI161077878, Length=565, Percent_Identity=29.5575221238938, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI161077496, Length=529, Percent_Identity=26.8431001890359, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI18859741, Length=584, Percent_Identity=25.8561643835616, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 66190; Mature: 66190

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRIRPHSRPWTLAAAVAFALVAFGAGCTSPSAPSGAVVPVAAASGAAVPLPGVHSPEL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
SSGWTDKPGWTSQHAMIAAANPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIG
CCCCCCCCCCCCCCEEEEECCCHHHHHCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
GGAFMLYFDGHATQAYDGRETAPAAATERLFYGPTGQPMRFYEGVVGGRSVGTPGVLRML
CCEEEEEEECCCCCCCCCCCCCCHHHHCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHHH
DAAHRAHGKLPWRRLFQPAIRLAEHGFTISPRLAMLIANDKYLMNDPAARAYFYNDDGTP
HHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEECCCEEECCCCCEEEEECCCCCC
KAAGTVLKNPALATVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSLQDLARYKA
HHHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHH
KVRAPLCTDYRRSVVCGMPPPSSGGLAIAQMLGILETMPDWQQIGAQKPVRNEVGYEPTP
HHCCCCHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHCCCCCCC
FAAHLFSEAGRLAFADRARYVADPDFAPLPGGSWASLTDKAYLAQRARLIGDNSMGVAQA
HHHHHHHHCCCEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSVEDAFGSRLMVRGFMLNNQLT
CCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHCCCEEHEEEECCCCCC
DFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDQKTKQVTMIVGSAGGPAIINHVAKTL
CEEEECCCCCCCHHHHCCCCCCCCHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHH
IGVLDWGMTMQQAIALPNVGSTNGPTQLERGRVSDALVDGLKGRGHDVQVVELNSGLQGI
HHHHHCCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHH
QRLNLQGQTVWFGGADPRREGVAMGD
HHHCCCCCEEEECCCCCHHCCCCCCC
>Mature Secondary Structure
MFDRIRPHSRPWTLAAAVAFALVAFGAGCTSPSAPSGAVVPVAAASGAAVPLPGVHSPEL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
SSGWTDKPGWTSQHAMIAAANPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIG
CCCCCCCCCCCCCCEEEEECCCHHHHHCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
GGAFMLYFDGHATQAYDGRETAPAAATERLFYGPTGQPMRFYEGVVGGRSVGTPGVLRML
CCEEEEEEECCCCCCCCCCCCCCHHHHCCEEECCCCCCHHHHHHCCCCCCCCCHHHHHHH
DAAHRAHGKLPWRRLFQPAIRLAEHGFTISPRLAMLIANDKYLMNDPAARAYFYNDDGTP
HHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCEEEEEECCCEEECCCCCEEEEECCCCCC
KAAGTVLKNPALATVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSLQDLARYKA
HHHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHH
KVRAPLCTDYRRSVVCGMPPPSSGGLAIAQMLGILETMPDWQQIGAQKPVRNEVGYEPTP
HHCCCCHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHCCCCCCC
FAAHLFSEAGRLAFADRARYVADPDFAPLPGGSWASLTDKAYLAQRARLIGDNSMGVAQA
HHHHHHHHCCCEEEHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GTPQGAALALADDRSPELPSTSDIAIVDRYGQALSMTTSVEDAFGSRLMVRGFMLNNQLT
CCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHCCCEEHEEEECCCCCC
DFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDQKTKQVTMIVGSAGGPAIINHVAKTL
CEEEECCCCCCCHHHHCCCCCCCCHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHH
IGVLDWGMTMQQAIALPNVGSTNGPTQLERGRVSDALVDGLKGRGHDVQVVELNSGLQGI
HHHHHCCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHH
QRLNLQGQTVWFGGADPRREGVAMGD
HHHCCCCCEEEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA