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The map label for this gene is glpR [H]

Identifier: 115352778

GI number: 115352778

Start: 3005062

End: 3005934

Strand: Direct

Name: glpR [H]

Synonym: Bamb_2727

Alternate gene names: 115352778

Gene position: 3005062-3005934 (Clockwise)

Preceding gene: 115352774

Following gene: 115352779

Centisome position: 84.49

GC content: 67.81

Gene sequence:

>873_bases
ATGAATGACGGGCTACCGTGCGCCGCGCGCCGGCCGAACGCCCTTTCCGCCCCTTACAATACGCGCTCCGCCTCACGATC
CGACCGCCCAGCCATGACCCGAGATCCCCGCCTCACCCTCAACGCGCGCCAGCAGGAATTGCTCGAATGGGTGCAGCGCG
ACGGCTTCGTGACCGTCGACGATCTCGCCGCGCACTTCGCGGTCACGCCGCAGACGATCCGCCGCGACGTCAACTGGCTC
GCGGATCTGAACCTGCTGCGCCGCTACCACGGCGGCGCGAGCCTGCCGACCAGCTCGGAGAACGTGTCGTACACCGCGCG
CCAGCGGATGTTCCACGACGAGAAGCGGCGCATCGCGGCGCTGGCGGCATCGCACATCCCCGACCAGGCGTCGCTGTTCA
TCAACCTCGGCACGACGACCGAGGAAGTCGCGCGCGCGCTGAACCGCCATCACGGGCTGCATGTGATCACGAACAACCTG
AACGTCGCGTCGATGATGAGCGGCTATCCCGACTGCGAGGTGCTGATCACGGGCGGCATCGTGCGGCCGTGGGACAAGGG
GATCGTCGGCGAACTCGCGATCGACTTCATCCGCCAGTTCAAGGTCGACTACGCGATCATCGGCACGTCGGCGATCGAGG
CCGACGGCACGCTGCGCGACTTCGACACGCGCGAGGTGCGCGTGGCCGAGGCGATCATGCAGCATGCGCGCACGGTCTAC
CTCGTCGCCGACCACTCGAAGGTCGGCCGCCCGGCGCTCGTGCGCCAGGGGCATCTGAGCCAGGTCCATGCGCTCTTCAC
CGACAAGCCGCTGCCGCCGGAGATGGCCGACGCGGTAGCCGCCGCAGGCACCGAAGTGTACGTCGCTGAATAA

Upstream 100 bases:

>100_bases
CGCCGCGCGCAGGCTCGGCGTGCGCGGACAGTCCGCCATTGCAGCGCGATCCGCGCGATCGCGCAAATTCATTTGTCAAA
TTAATCCATGCACTTTTCGC

Downstream 100 bases:

>100_bases
CGCTTGCGATGCTGCACCGCACCCGAAACTTCAAGTGAAATCAAGAAGTTGGCGCACCGACCGAACCGCTAGCGACCCGC
GTGCCTGTCAAACGGAAAAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MNDGLPCAARRPNALSAPYNTRSASRSDRPAMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRDVNWL
ADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVITNNL
NVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHARTVY
LVADHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADAVAAAGTEVYVAE

Sequences:

>Translated_290_residues
MNDGLPCAARRPNALSAPYNTRSASRSDRPAMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRDVNWL
ADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVITNNL
NVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHARTVY
LVADHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADAVAAAGTEVYVAE
>Mature_290_residues
MNDGLPCAARRPNALSAPYNTRSASRSDRPAMTRDPRLTLNARQQELLEWVQRDGFVTVDDLAAHFAVTPQTIRRDVNWL
ADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALAASHIPDQASLFINLGTTTEEVARALNRHHGLHVITNNL
NVASMMSGYPDCEVLITGGIVRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHARTVY
LVADHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADAVAAAGTEVYVAE

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=230, Percent_Identity=47.3913043478261, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI87082344, Length=237, Percent_Identity=42.1940928270042, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1788069, Length=230, Percent_Identity=29.1304347826087, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=29.4354838709677, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790753, Length=249, Percent_Identity=26.9076305220884, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=26.1044176706827, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=28.5140562248996, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=29.1845493562232, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787063, Length=239, Percent_Identity=27.6150627615063, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=25.6916996047431, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 32084; Mature: 32084

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDGLPCAARRPNALSAPYNTRSASRSDRPAMTRDPRLTLNARQQELLEWVQRDGFVTVD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCEEHH
DLAAHFAVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LAASHIPDQASLFINLGTTTEEVARALNRHHGLHVITNNLNVASMMSGYPDCEVLITGGI
HHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCEEEEECCC
VRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHARTVY
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHCCEEE
LVADHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADAVAAAGTEVYVAE
EEECCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MNDGLPCAARRPNALSAPYNTRSASRSDRPAMTRDPRLTLNARQQELLEWVQRDGFVTVD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHCCCEEHH
DLAAHFAVTPQTIRRDVNWLADLNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LAASHIPDQASLFINLGTTTEEVARALNRHHGLHVITNNLNVASMMSGYPDCEVLITGGI
HHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCEEEEECCC
VRPWDKGIVGELAIDFIRQFKVDYAIIGTSAIEADGTLRDFDTREVRVAEAIMQHARTVY
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHCCEEE
LVADHSKVGRPALVRQGHLSQVHALFTDKPLPPEMADAVAAAGTEVYVAE
EEECCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]