Click here to switch to the map view.

The map label for this gene is erg3 [H]

Identifier: 115352718

GI number: 115352718

Start: 2938064

End: 2938978

Strand: Direct

Name: erg3 [H]

Synonym: Bamb_2667

Alternate gene names: 115352718

Gene position: 2938064-2938978 (Clockwise)

Preceding gene: 115352717

Following gene: 115352719

Centisome position: 82.61

GC content: 65.14

Gene sequence:

>915_bases
ATGCGATTCGACGTCGAATTGCTTCTGCTCGCGCTGGCGCCCGTCTTCCTGCTCTGCATCGCGTGGGAGGCCTGGCACCT
CGCCCGCACGCGTGCGCACGACCATGTCTATGCGTGGCGCGACACGCTGTGCAACGCGGCGCTCGCGCTGATGCACCAGG
GCGCCGACAAGCTCGCGTGGCTGTTCGTGATCCCCGTTTATGCGTACTGCTACGCACATTTCCGGCTGTTCACGTGGCAC
GACGGCTGGCTGTCGTTCGCCGTGCTGTTCATCGGCCAGGACTTCCTCTACTACGTGTTCCATCGCGCGAGCCATCGCGT
GCGCTGGCTGTGGGCCGCGCACGTCGTGCACCACTCGTCCGAGCGGATGAATTTCTCGACCGCGTTCCGGCAGAGCCTGA
TGTATCCCGTCGCGGGCATGTGGGCGTTCTGGCTGCCGCTCGCGTTCGTCGGCTTTCCGCCGCAGCAGATCGTCGGCGTC
GTGCTGATCAACCTCGCGTTCCAGTTCTTCGTGCACACGCAGGCGATCGGCAAGCTCGGCTGGCTCGAATACGTGTTCAA
CACGCCGTCGATCCATCGCGCGCACCATGCCCGCAACCCGCGCTACATCGACCGCAATTACGCAGGTGTGCTCGTGATCT
GGGATCGCCTGTTCGGCAGCTACGTCGAGGAGTCGCCCGACGATCCGCCGCGCTATGGAATCGTCGAGCCGCTCGGCTCG
AACAACCCGCTCGTCGCGACGTTCCACGAGTGGGTGTCGATGGCGGCCGACGCGTTGCGCATCGACGGATGGCGCAACAA
GCTGCGCGCGATTTTCGGCCCGCCCGAATGGGCGAGCGCTTATCATGCGCAGATTGCAGAGGCCGCGAACCAGGATCCGC
GCGCCGTGCCGCTTGCGGCTGCGCGTGACCAATAA

Upstream 100 bases:

>100_bases
CTAGCGCGTGGCGATTGCGTAGGCTGTTGGCCTGACCGATATCTACAACGGGCCATGGGCCCGGCCTCACGGCTTGCAGG
GGAAAGGAGGAGACACGTCC

Downstream 100 bases:

>100_bases
ACCGTTTCAGCCAACGGCCGCCGCGCAGCCCGGAACCGGGCAGGCACGCGGCAGATGAGAAATACATCAGGCCATATCTA
CGAGGAGATAGAACGATGCA

Product: sterol desaturase-like protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAHDHVYAWRDTLCNAALALMHQGADKLAWLFVIPVYAYCYAHFRLFTWH
DGWLSFAVLFIGQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWAFWLPLAFVGFPPQQIVGV
VLINLAFQFFVHTQAIGKLGWLEYVFNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEESPDDPPRYGIVEPLGS
NNPLVATFHEWVSMAADALRIDGWRNKLRAIFGPPEWASAYHAQIAEAANQDPRAVPLAAARDQ

Sequences:

>Translated_304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAHDHVYAWRDTLCNAALALMHQGADKLAWLFVIPVYAYCYAHFRLFTWH
DGWLSFAVLFIGQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWAFWLPLAFVGFPPQQIVGV
VLINLAFQFFVHTQAIGKLGWLEYVFNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEESPDDPPRYGIVEPLGS
NNPLVATFHEWVSMAADALRIDGWRNKLRAIFGPPEWASAYHAQIAEAANQDPRAVPLAAARDQ
>Mature_304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAHDHVYAWRDTLCNAALALMHQGADKLAWLFVIPVYAYCYAHFRLFTWH
DGWLSFAVLFIGQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWAFWLPLAFVGFPPQQIVGV
VLINLAFQFFVHTQAIGKLGWLEYVFNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEESPDDPPRYGIVEPLGS
NNPLVATFHEWVSMAADALRIDGWRNKLRAIFGPPEWASAYHAQIAEAANQDPRAVPLAAARDQ

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=246, Percent_Identity=39.0243902439024, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25144659, Length=257, Percent_Identity=35.408560311284, Blast_Score=147, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35100; Mature: 35100

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAHDHVYAWRDTLCNAALALMHQGADKLAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LFVIPVYAYCYAHFRLFTWHDGWLSFAVLFIGQDFLYYVFHRASHRVRWLWAAHVVHHSS
HHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCH
ERMNFSTAFRQSLMYPVAGMWAFWLPLAFVGFPPQQIVGVVLINLAFQFFVHTQAIGKLG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLEYVFNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEESPDDPPRYGIVEPLGS
HHHHHHCCCCHHHHHHCCCCCEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCC
NNPLVATFHEWVSMAADALRIDGWRNKLRAIFGPPEWASAYHAQIAEAANQDPRAVPLAA
CCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
ARDQ
CCCC
>Mature Secondary Structure
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAHDHVYAWRDTLCNAALALMHQGADKLAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LFVIPVYAYCYAHFRLFTWHDGWLSFAVLFIGQDFLYYVFHRASHRVRWLWAAHVVHHSS
HHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCH
ERMNFSTAFRQSLMYPVAGMWAFWLPLAFVGFPPQQIVGVVLINLAFQFFVHTQAIGKLG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLEYVFNTPSIHRAHHARNPRYIDRNYAGVLVIWDRLFGSYVEESPDDPPRYGIVEPLGS
HHHHHHCCCCHHHHHHCCCCCEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCC
NNPLVATFHEWVSMAADALRIDGWRNKLRAIFGPPEWASAYHAQIAEAANQDPRAVPLAA
CCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
ARDQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]