Click here to switch to the map view.

The map label for this gene is argF [H]

Identifier: 115352652

GI number: 115352652

Start: 2864142

End: 2865824

Strand: Direct

Name: argF [H]

Synonym: Bamb_2601

Alternate gene names: 115352652

Gene position: 2864142-2865824 (Clockwise)

Preceding gene: 115352651

Following gene: 115352654

Centisome position: 80.53

GC content: 63.28

Gene sequence:

>1683_bases
ATGCGCGCTCGTCCGTCGATCTCACTTCTTCTCGTTGTAGTCCGGCAGCTCGCACGCCTCGGTGACGACGAGGTTGTTGT
CCTTCGCGAAATTCAGCACGAAATCGAATGCCATCGGCTCGATGTCGCGCAGCCGGGAATCGAGGATCACGCATTTCAGC
TCGCCGAGCATCGTCGGGCGCACGTACAGCGAATATTTCAGGCGCGCGTTCGGGCCGCTCGCGCCGGGCCCGAAGCAGGC
CATCACGCCGGCCAGACGCTCCGACCAGTCGCTCGGGCGAAACTTTTTCCCGTCTTTCGTGATGCCCTGGATGAAGAATT
CGGTCGGAGGGGTTTCAGCCATGTGGTTACCCAAGTGACGGCCCGGCGATGTCCAGGCGACGGCGCCTGGATACGCGAAC
ACAAAGCTGGAGTGGACGACACACGCGCTTCGATATCCCGAAAACAGGCCGTCGATGCGTGCCGCCGGCGCGCCGCACCG
GATGTGTGCAGCGCATGGCTTGTGTCCGGCAGAGCGCGAAAAGCCTTGCCTGCCGGGCTGGAGAAAACTTTTGGATTATA
CCGCAGCGCGCCATCGCGCGTCGTCTCGCCACCCCTCTCCCGGCGTGCTCCAGCGTGCGCGACGATGCCGCCCCGGTTTG
TGGCGCGGCTCGTCAAAGCACAGAAAATCCTTTATGCTGCTTTGCAGTTATCCACACCCGACGGCTGCCGCGTCCGGCTC
CGCAGCCGGCTCCAACCCGCCGTATTTCGTTTCATGACCGCCAAAACCATTCGTCACTACCTGCAGTTCAAGGATTTCTC
GCTGGAAGACTACGAGTACGTGCTCGAACGCACGGGTATCCTGAAGCGCAAGTTCAAGAACTACGAGACCTATCACCCGC
TGCACGACCGCACGCTCGCGATGATCTTCGAGAAGAGCTCGACGCGCACGCGGCTGTCGTTCGAAGCCGGCATCTTCCAG
CTGGGCGGCCACGCGGTGTTCATGAGCACGCGCGACACGCAGCTCGGCCGCGGCGAGCCCGTCGAGGATTCCGCGCAGGT
CATCTCGCGAATGGTCGACATCATCATGATCCGCACGTTCGAGCAGGACGTGATCACGCGCTTCGCGCAGAACTCCCGCG
TGCCGGTGATCAACGGCCTGACCAACGATTACCACCCGTGCCAGGTGCTCGCCGACATCTTCACGTACTACGAGCACCGC
GGCCCGATCGCCGGCAAGACCGTCGCATGGGTCGGTGATGCGAACAACATGCTGTACACGTGGATCGAAGCCGCGCAGAT
CCTCGGCTTCAAGTTGCGCCTGTCGACGCCGCCGGGCTATGCGCTCGACATGAAGCTCGTGTCGCCGGACAGCGCGCCGT
TCTACGAAGTGTTCGACGATCCGAACGAAGCGTGCAAGGGCGCCGATCTCGTGACGACCGACGTGTGGACGAGCATGGGC
TTCGAGGCCGAGAACGAAGCGCGCATGCAGGCGTTTGCCGACTGGTGCGTCGACGAGGAAATGATGGGCCACGCGAACGC
GGACGCGCTCTTCATGCACTGCCTGCCCGCGCACCGCGGCGAGGAAGTGACGGCCGGCGTGATCGACGGCCCGCAGAGCG
TCGTGTGGGACGAGGCGGAAAACCGCCTGCACGTGCAGAAGGCGCTGATGGAGTTCCTGCTGCTCGGCCGCCTGAAGCAC
TGA

Upstream 100 bases:

>100_bases
GCGTTCCTGTTTCCTGCGATCGCAAAAAAGCCCGCCTAGGCGGGCTTTTTTGCGTGTCGTCCGCGCATCGCACCGGACGA
CCACCAGACGCGAGCGCGGC

Downstream 100 bases:

>100_bases
ACGCAGCACTCGCGCGCCGCCTGAATCCGGCGGCATGCAAAGAAAAGCGCCGATCGATGATCGGCGCTTTTTGTTTGCGC
GGGCGAAAGCGCATGAAAGG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MRARPSISLLLVVVRQLARLGDDEVVVLREIQHEIECHRLDVAQPGIEDHAFQLAEHRRAHVQRIFQARVRAARAGPEAG
HHAGQTLRPVARAKLFPVFRDALDEEFGRRGFSHVVTQVTARRCPGDGAWIREHKAGVDDTRASISRKQAVDACRRRAAP
DVCSAWLVSGRARKALPAGLEKTFGLYRSAPSRVVSPPLSRRAPACATMPPRFVARLVKAQKILYAALQLSTPDGCRVRL
RSRLQPAVFRFMTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQ
LGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQNSRVPVINGLTNDYHPCQVLADIFTYYEHR
GPIAGKTVAWVGDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMG
FEAENEARMQAFADWCVDEEMMGHANADALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Sequences:

>Translated_560_residues
MRARPSISLLLVVVRQLARLGDDEVVVLREIQHEIECHRLDVAQPGIEDHAFQLAEHRRAHVQRIFQARVRAARAGPEAG
HHAGQTLRPVARAKLFPVFRDALDEEFGRRGFSHVVTQVTARRCPGDGAWIREHKAGVDDTRASISRKQAVDACRRRAAP
DVCSAWLVSGRARKALPAGLEKTFGLYRSAPSRVVSPPLSRRAPACATMPPRFVARLVKAQKILYAALQLSTPDGCRVRL
RSRLQPAVFRFMTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQ
LGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQNSRVPVINGLTNDYHPCQVLADIFTYYEHR
GPIAGKTVAWVGDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMG
FEAENEARMQAFADWCVDEEMMGHANADALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH
>Mature_560_residues
MRARPSISLLLVVVRQLARLGDDEVVVLREIQHEIECHRLDVAQPGIEDHAFQLAEHRRAHVQRIFQARVRAARAGPEAG
HHAGQTLRPVARAKLFPVFRDALDEEFGRRGFSHVVTQVTARRCPGDGAWIREHKAGVDDTRASISRKQAVDACRRRAAP
DVCSAWLVSGRARKALPAGLEKTFGLYRSAPSRVVSPPLSRRAPACATMPPRFVARLVKAQKILYAALQLSTPDGCRVRL
RSRLQPAVFRFMTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQ
LGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQDVITRFAQNSRVPVINGLTNDYHPCQVLADIFTYYEHR
GPIAGKTVAWVGDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMG
FEAENEARMQAFADWCVDEEMMGHANADALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=39.1447368421053, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI18105007, Length=372, Percent_Identity=25, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=36.9230769230769, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=35.0769230769231, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI2367364, Length=311, Percent_Identity=27.6527331189711, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=295, Percent_Identity=26.1016949152542, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=326, Percent_Identity=32.5153374233129, Blast_Score=189, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6322331, Length=304, Percent_Identity=24.6710526315789, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24642586, Length=321, Percent_Identity=26.1682242990654, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 63186; Mature: 63186

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARPSISLLLVVVRQLARLGDDEVVVLREIQHEIECHRLDVAQPGIEDHAFQLAEHRRA
CCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
HVQRIFQARVRAARAGPEAGHHAGQTLRPVARAKLFPVFRDALDEEFGRRGFSHVVTQVT
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRCPGDGAWIREHKAGVDDTRASISRKQAVDACRRRAAPDVCSAWLVSGRARKALPAGL
HHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCHH
EKTFGLYRSAPSRVVSPPLSRRAPACATMPPRFVARLVKAQKILYAALQLSTPDGCRVRL
HHHHHHHHCCCCHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RSRLQPAVFRFMTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLA
HHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEE
MIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTF
EEEECCCCCEEEEHHHCHHEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EQDVITRFAQNSRVPVINGLTNDYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYT
HHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
WIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMG
HHHHHHHHCEEEEECCCCCCEEEEEEECCCCCCCHHHCCCHHHHHCCCCEEEHHHHHHCC
FEAENEARMQAFADWCVDEEMMGHANADALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAE
CCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
NRLHVQKALMEFLLLGRLKH
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRARPSISLLLVVVRQLARLGDDEVVVLREIQHEIECHRLDVAQPGIEDHAFQLAEHRRA
CCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
HVQRIFQARVRAARAGPEAGHHAGQTLRPVARAKLFPVFRDALDEEFGRRGFSHVVTQVT
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRCPGDGAWIREHKAGVDDTRASISRKQAVDACRRRAAPDVCSAWLVSGRARKALPAGL
HHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCHH
EKTFGLYRSAPSRVVSPPLSRRAPACATMPPRFVARLVKAQKILYAALQLSTPDGCRVRL
HHHHHHHHCCCCHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RSRLQPAVFRFMTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLA
HHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEE
MIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTF
EEEECCCCCEEEEHHHCHHEECCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
EQDVITRFAQNSRVPVINGLTNDYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYT
HHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
WIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMG
HHHHHHHHCEEEEECCCCCCEEEEEEECCCCCCCHHHCCCHHHHHCCCCEEEHHHHHHCC
FEAENEARMQAFADWCVDEEMMGHANADALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAE
CCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
NRLHVQKALMEFLLLGRLKH
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA