Click here to switch to the map view.

The map label for this gene is prlC [H]

Identifier: 115352229

GI number: 115352229

Start: 2394843

End: 2396930

Strand: Direct

Name: prlC [H]

Synonym: Bamb_2178

Alternate gene names: 115352229

Gene position: 2394843-2396930 (Clockwise)

Preceding gene: 115352228

Following gene: 115352231

Centisome position: 67.34

GC content: 67.86

Gene sequence:

>2088_bases
ATGTCCGCCAGCGCCAATACCAATCCGCTCCTCGATTTCTCCGGCCTGCCCCGCTTCGGCGAGATTCGTCCGGAACATGT
GACGCCCGCGCTCGACACGCTGCTCGACACCGCCAACCGCGCGGTCGACACCGCGAGCGCACCCGCGACGCCGGCGACCT
GGGCCACGATCGTCGAGACGGTCGAGCAGGCGACGGAGCCGCTCGGGCGCGCATGGGGCGTCGTCGGCCATCTGAACGCG
GTCGCCGATACGCCGGAACTGCGGGCCGCCTACGGCGAAAACCTGCCACGCGTGACCGAATTCTGGTCGAGCGTCGGCCA
GAACCTCGCGCTGTACGAGAAGTACAAGGCGATCGCCGCGAGCGCCGAATACGCGACGCTGTCCGCCGAGCGCAAGAAGA
TCCTCGACAACGCGCTGCGCGATTTCCGCCTGTCGGGCGCCGAGCTGCCGGAAGACCAGAAGCCGCGCTTCGCGGAACTG
CAGGAGCAGCAGGCCGCGCTGTCGAAGGCGTTCTCCGACCACGTGCTCGACGCGACCAACGCGTATGCGTACTTCGCGCA
GGACGAGGCCGAACTCGCCGGCCTGCCGGGCGACGCGATCGAAGCGGCCCGCGAAGCCGCGCAGAAGGAAGGCAAGGAAG
GCTGGAAATTCACGCTGCACTTCCCGTCCTACTTCCCGGTGCTGCAATACGCGGAGAACCGCGCGATGCGCGAGACGCTG
TATCGCGCGTATGCGACGCGCGCCTCCGAACTCGGGCCGCAGTACGGCGGCGGCAAGGCCGAATGGGACAACACGGCGAT
CGTCGCCGACGAGCTGAAGCTGCGCCGTGAAGAGGCACAGATGCTCGGCTACCGCAACTTCGCCGAAGTGTCGCTCGCGC
CGAAGATGGCCGAGTCGCCGCAGCAGGTCATCGCGTTCCTCGAGGATCTCGCGACGCGCGCGCGCCCGCACGCCGACAAG
GACTGGGACGAACTGCGCGCGTTCGCCGCGAAGGAACTCGGCCTGACCGAACTCGCGCCGTGGGACGTCGCGTTCGCGGC
CGAGCGGCTGCGCCAGCAGCGCTACGCGTTCTCGGAAAACGAGGTCAAGCAGTACTTCCCGGAACCGGCCGTGCTGAAGG
GCCTCTTCACCGTCACCGAAACGCTGTTCGGCGTGCGGATCAAGCCGGACGACGCGCCGGTCTGGCACCGGGACGTGCGC
TTTTTCCGCGTCGAGAACCGCGACGGCTCGCTCGTCGCGCAGTTCTATCTCGACCTGTATGCACGCGAAGGCAAGCGCGG
CGGCGCGTGGATGGACGATGCGCGTGCGCGCGCGAAGCGCGGCGGCACCGTGCAGACGCCGGTCGCGTACCTGACCTGCA
ACTTCTCGGCGCCGGTCGGCGGCAAGCCCGCGTGCTTCACGCACGACGAAGTCATCACGCTGTTCCATGAATTCGGCCAC
GGGCTGCATCACATGCTCACGCGCGTCGACGAGCTCGGCGTGTCGGGCATCAACGGCGTCGAATGGGATGCGGTCGAGCT
GCCGTCGCAGTTCATGGAAAACTTCTGCTGGGAATGGGACGTGCTGTCGTCGATGTCGTCGCACATCGATACCGGCGCGT
CGCTGCCGCGCGAGCTGTTCGACAAGATGATCGCCGCGAAGAACTTCCAGAGCGGCCTCGGCACGCTGCGCCAGATCGTG
TTCTCGATGTTCGACATGCTGCTGCACGTCGACTTCGACCCGGCCGGCGCGACCGGCGTGAATGCGTTCGCGCGCGAGAT
CAACGAGCGCTACCACGTGATCCCGCAGGCAGCGTTCTCGCGCTGGCCGAACACGTTCAGCCACATCTTCGCGGGCGGCT
ATGCGGCCGGCTACTACAGCTACAAGTGGGCCGAGGTGCTGTCGGCCGACGCGTACGCGGCGTTCGAGGAAGCGGCCGCC
GCAGGCGGCAGCGTGCTCGACGCGGCGACCGGCACGCGCTATCGCCGCGAGATCCTCGAAGTCGGCGGCAGCCGCCCGGC
GATGGATTCGTTCAAGGCGTTCCGCGGCCGCGAGCCGGAAATCGACGCGCTGCTGCGCCACAACGGGATGACCTCCGCCG
CGCACTGA

Upstream 100 bases:

>100_bases
AAAGCGCGCGATGCGCCCCAATAATGTCGGTATCGGGCGCCGCTGCTTCGCGCCTCACCCTTTTCACCCCGGTTCATCCG
GCAACAGACAGGGAGTCTTA

Downstream 100 bases:

>100_bases
GCACGCGCTGGCCGGTTCGGCCCGCTGCTTTGGAAGGCACCGCTTCGGCGGTGCCTTTTTTCATGGTGCGGGGGGTTTGG
CGTTGGCGGCGTTGGCAGCA

Product: oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MSASANTNPLLDFSGLPRFGEIRPEHVTPALDTLLDTANRAVDTASAPATPATWATIVETVEQATEPLGRAWGVVGHLNA
VADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAASAEYATLSAERKKILDNALRDFRLSGAELPEDQKPRFAEL
QEQQAALSKAFSDHVLDATNAYAYFAQDEAELAGLPGDAIEAAREAAQKEGKEGWKFTLHFPSYFPVLQYAENRAMRETL
YRAYATRASELGPQYGGGKAEWDNTAIVADELKLRREEAQMLGYRNFAEVSLAPKMAESPQQVIAFLEDLATRARPHADK
DWDELRAFAAKELGLTELAPWDVAFAAERLRQQRYAFSENEVKQYFPEPAVLKGLFTVTETLFGVRIKPDDAPVWHRDVR
FFRVENRDGSLVAQFYLDLYAREGKRGGAWMDDARARAKRGGTVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
GLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHIDTGASLPRELFDKMIAAKNFQSGLGTLRQIV
FSMFDMLLHVDFDPAGATGVNAFAREINERYHVIPQAAFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAA
AGGSVLDAATGTRYRREILEVGGSRPAMDSFKAFRGREPEIDALLRHNGMTSAAH

Sequences:

>Translated_695_residues
MSASANTNPLLDFSGLPRFGEIRPEHVTPALDTLLDTANRAVDTASAPATPATWATIVETVEQATEPLGRAWGVVGHLNA
VADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAASAEYATLSAERKKILDNALRDFRLSGAELPEDQKPRFAEL
QEQQAALSKAFSDHVLDATNAYAYFAQDEAELAGLPGDAIEAAREAAQKEGKEGWKFTLHFPSYFPVLQYAENRAMRETL
YRAYATRASELGPQYGGGKAEWDNTAIVADELKLRREEAQMLGYRNFAEVSLAPKMAESPQQVIAFLEDLATRARPHADK
DWDELRAFAAKELGLTELAPWDVAFAAERLRQQRYAFSENEVKQYFPEPAVLKGLFTVTETLFGVRIKPDDAPVWHRDVR
FFRVENRDGSLVAQFYLDLYAREGKRGGAWMDDARARAKRGGTVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
GLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHIDTGASLPRELFDKMIAAKNFQSGLGTLRQIV
FSMFDMLLHVDFDPAGATGVNAFAREINERYHVIPQAAFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAA
AGGSVLDAATGTRYRREILEVGGSRPAMDSFKAFRGREPEIDALLRHNGMTSAAH
>Mature_694_residues
SASANTNPLLDFSGLPRFGEIRPEHVTPALDTLLDTANRAVDTASAPATPATWATIVETVEQATEPLGRAWGVVGHLNAV
ADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAASAEYATLSAERKKILDNALRDFRLSGAELPEDQKPRFAELQ
EQQAALSKAFSDHVLDATNAYAYFAQDEAELAGLPGDAIEAAREAAQKEGKEGWKFTLHFPSYFPVLQYAENRAMRETLY
RAYATRASELGPQYGGGKAEWDNTAIVADELKLRREEAQMLGYRNFAEVSLAPKMAESPQQVIAFLEDLATRARPHADKD
WDELRAFAAKELGLTELAPWDVAFAAERLRQQRYAFSENEVKQYFPEPAVLKGLFTVTETLFGVRIKPDDAPVWHRDVRF
FRVENRDGSLVAQFYLDLYAREGKRGGAWMDDARARAKRGGTVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGHG
LHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHIDTGASLPRELFDKMIAAKNFQSGLGTLRQIVF
SMFDMLLHVDFDPAGATGVNAFAREINERYHVIPQAAFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAAA
GGSVLDAATGTRYRREILEVGGSRPAMDSFKAFRGREPEIDALLRHNGMTSAAH

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=622, Percent_Identity=31.3504823151125, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI14149738, Length=628, Percent_Identity=30.5732484076433, Blast_Score=279, Evalue=8e-75,
Organism=Homo sapiens, GI156105687, Length=694, Percent_Identity=25.3602305475504, Blast_Score=177, Evalue=3e-44,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=49.8542274052478, Blast_Score=689, Evalue=0.0,
Organism=Escherichia coli, GI1787819, Length=693, Percent_Identity=31.1688311688312, Blast_Score=276, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI71999758, Length=525, Percent_Identity=24.952380952381, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32565901, Length=595, Percent_Identity=22.0168067226891, Blast_Score=97, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319793, Length=694, Percent_Identity=28.8184438040346, Blast_Score=279, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6322715, Length=682, Percent_Identity=23.0205278592375, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21356111, Length=693, Percent_Identity=26.4069264069264, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI20129717, Length=564, Percent_Identity=25.531914893617, Blast_Score=161, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 77066; Mature: 76935

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASANTNPLLDFSGLPRFGEIRPEHVTPALDTLLDTANRAVDTASAPATPATWATIVET
CCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VEQATEPLGRAWGVVGHLNAVADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
SAEYATLSAERKKILDNALRDFRLSGAELPEDQKPRFAELQEQQAALSKAFSDHVLDATN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
AYAYFAQDEAELAGLPGDAIEAAREAAQKEGKEGWKFTLHFPSYFPVLQYAENRAMRETL
CEEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
YRAYATRASELGPQYGGGKAEWDNTAIVADELKLRREEAQMLGYRNFAEVSLAPKMAESP
HHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCH
QQVIAFLEDLATRARPHADKDWDELRAFAAKELGLTELAPWDVAFAAERLRQQRYAFSEN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHH
EVKQYFPEPAVLKGLFTVTETLFGVRIKPDDAPVWHRDVRFFRVENRDGSLVAQFYLDLY
HHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCCCHHCCCEEEEEECCCCHHHHHHHHHHH
AREGKRGGAWMDDARARAKRGGTVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
HHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHH
GLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHIDTGASLPRELF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHH
DKMIAAKNFQSGLGTLRQIVFSMFDMLLHVDFDPAGATGVNAFAREINERYHVIPQAAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
RWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAAAGGSVLDAATGTRYRREILE
HCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHH
VGGSRPAMDSFKAFRGREPEIDALLRHNGMTSAAH
CCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SASANTNPLLDFSGLPRFGEIRPEHVTPALDTLLDTANRAVDTASAPATPATWATIVET
CCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VEQATEPLGRAWGVVGHLNAVADTPELRAAYGENLPRVTEFWSSVGQNLALYEKYKAIAA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
SAEYATLSAERKKILDNALRDFRLSGAELPEDQKPRFAELQEQQAALSKAFSDHVLDATN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
AYAYFAQDEAELAGLPGDAIEAAREAAQKEGKEGWKFTLHFPSYFPVLQYAENRAMRETL
CEEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
YRAYATRASELGPQYGGGKAEWDNTAIVADELKLRREEAQMLGYRNFAEVSLAPKMAESP
HHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCH
QQVIAFLEDLATRARPHADKDWDELRAFAAKELGLTELAPWDVAFAAERLRQQRYAFSEN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHH
EVKQYFPEPAVLKGLFTVTETLFGVRIKPDDAPVWHRDVRFFRVENRDGSLVAQFYLDLY
HHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCCCHHCCCEEEEEECCCCHHHHHHHHHHH
AREGKRGGAWMDDARARAKRGGTVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHEFGH
HHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEECHHHHHHHHHHHHH
GLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSSMSSHIDTGASLPRELF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHH
DKMIAAKNFQSGLGTLRQIVFSMFDMLLHVDFDPAGATGVNAFAREINERYHVIPQAAFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
RWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAAAGGSVLDAATGTRYRREILE
HCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHH
VGGSRPAMDSFKAFRGREPEIDALLRHNGMTSAAH
CCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]