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The map label for this gene is gbpR [H]

Identifier: 115351673

GI number: 115351673

Start: 1793138

End: 1794076

Strand: Direct

Name: gbpR [H]

Synonym: Bamb_1620

Alternate gene names: 115351673

Gene position: 1793138-1794076 (Clockwise)

Preceding gene: 115351671

Following gene: 115351674

Centisome position: 50.42

GC content: 63.79

Gene sequence:

>939_bases
ATGATCCCGCCCGCATCCACTCTTCGAAGCCGCCTGAAGATGCAGCATCTGCGCTTGCTGCTGTCGATCGAGGAGCGCGG
TTCGTTGCGCCAGGCGGCGGACGCGCTTTCGCTATCGCAGCCGGCGGTGACGAAGATGCTTCAGGACATGGAAGCGCTGC
TGGGCGTCACGTTGTTCGAGCGGCATCTTCGCGGACTTCGACCCACACGCTTCGGCATGGCGGTCACGCGCTACGCGAAC
CTCGTCTTCTCGGACCTGGCCAATCTGCATGACGAACTGGTGTCGCTTGAAACGGGCAGGATCGGCAAGGTGCGCATCGG
TGCGGTCATGGCTCCGACACCGGTGCTGATGGCGGAAGTGATCCGCCGGCTCAAGCGCGATCATCCCGGGCTCAACATGA
CAGTTCACGTCGATACCAGCGACATGCTCGTGCCGATGCTCGAGCGCGATCAACTCGATCTGGTGCTCGGGCGCGTGCCG
GAAGGCTGGGATGCCAGTCATTTGACCTTCGAGCAACTGGGTGACGAGCGGCTTGCTGTCGTGGTGGGATGCGATCACCC
GTTGGCGAAGCGGACTGATCCCACGTTCGGTGAGCTGGCCACTTACCCGTGGATTCTTCAACCGCGTCCGAGCCCGATGC
GTGCATTGATCGATCGTTCGTTCGAGGAGGCGGGCGTCACGGCGCCGCAGAGCACCATCGAAACCGCGGCGATCCTGATG
ACGACCTCATTGTTGACCGGCAGCGATCTGGTTGCCGTTGTCCCGATGGCGGTCGCGACGTTTCACGCGAGCATGGGCCT
GCTGCACATCCTGCCCGTACCGCTGCCGCGCAAGCTCGACCCGTACGGCATCGTCACGCGCCTGGGTCGTCCACCGAGCG
CGTCGATGACGTTGTTCGTCGACGTGTTGCGGGCGGTGGTCGAGGAGGGCGGCCAGTAG

Upstream 100 bases:

>100_bases
TTTTTCTATGCCTCGATAACTATTTTTGATATCCCGGCGAACGCCCCCCAACGTTCTTCCTTCATCGTTGGCAGCCAGTT
CCTTTCCTTTCGAGCGTTCC

Downstream 100 bases:

>100_bases
TAGAGGGGGATCAGGCTATATCGGCGTTGATGATCAATGACACGGGCTATCTCCGGGGCGAGCACGATATCGCCGCGCGC
GAATTGAGCGATGTCGTGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MIPPASTLRSRLKMQHLRLLLSIEERGSLRQAADALSLSQPAVTKMLQDMEALLGVTLFERHLRGLRPTRFGMAVTRYAN
LVFSDLANLHDELVSLETGRIGKVRIGAVMAPTPVLMAEVIRRLKRDHPGLNMTVHVDTSDMLVPMLERDQLDLVLGRVP
EGWDASHLTFEQLGDERLAVVVGCDHPLAKRTDPTFGELATYPWILQPRPSPMRALIDRSFEEAGVTAPQSTIETAAILM
TTSLLTGSDLVAVVPMAVATFHASMGLLHILPVPLPRKLDPYGIVTRLGRPPSASMTLFVDVLRAVVEEGGQ

Sequences:

>Translated_312_residues
MIPPASTLRSRLKMQHLRLLLSIEERGSLRQAADALSLSQPAVTKMLQDMEALLGVTLFERHLRGLRPTRFGMAVTRYAN
LVFSDLANLHDELVSLETGRIGKVRIGAVMAPTPVLMAEVIRRLKRDHPGLNMTVHVDTSDMLVPMLERDQLDLVLGRVP
EGWDASHLTFEQLGDERLAVVVGCDHPLAKRTDPTFGELATYPWILQPRPSPMRALIDRSFEEAGVTAPQSTIETAAILM
TTSLLTGSDLVAVVPMAVATFHASMGLLHILPVPLPRKLDPYGIVTRLGRPPSASMTLFVDVLRAVVEEGGQ
>Mature_312_residues
MIPPASTLRSRLKMQHLRLLLSIEERGSLRQAADALSLSQPAVTKMLQDMEALLGVTLFERHLRGLRPTRFGMAVTRYAN
LVFSDLANLHDELVSLETGRIGKVRIGAVMAPTPVLMAEVIRRLKRDHPGLNMTVHVDTSDMLVPMLERDQLDLVLGRVP
EGWDASHLTFEQLGDERLAVVVGCDHPLAKRTDPTFGELATYPWILQPRPSPMRALIDRSFEEAGVTAPQSTIETAAILM
TTSLLTGSDLVAVVPMAVATFHASMGLLHILPVPLPRKLDPYGIVTRLGRPPSASMTLFVDVLRAVVEEGGQ

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=299, Percent_Identity=26.7558528428094, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI157672245, Length=263, Percent_Identity=27.7566539923954, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787601, Length=268, Percent_Identity=24.6268656716418, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=24.1496598639456, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789506, Length=243, Percent_Identity=20.9876543209877, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786508, Length=182, Percent_Identity=26.3736263736264, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787879, Length=200, Percent_Identity=26, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788481, Length=210, Percent_Identity=28.0952380952381, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787530, Length=256, Percent_Identity=24.21875, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34265; Mature: 34265

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPPASTLRSRLKMQHLRLLLSIEERGSLRQAADALSLSQPAVTKMLQDMEALLGVTLFE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RHLRGLRPTRFGMAVTRYANLVFSDLANLHDELVSLETGRIGKVRIGAVMAPTPVLMAEV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEECCCHHHHHHH
IRRLKRDHPGLNMTVHVDTSDMLVPMLERDQLDLVLGRVPEGWDASHLTFEQLGDERLAV
HHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHCCCCEEEE
VVGCDHPLAKRTDPTFGELATYPWILQPRPSPMRALIDRSFEEAGVTAPQSTIETAAILM
EEECCCCCCCCCCCCHHHHHCCCEEECCCCCHHHHHHHCCHHHCCCCCCHHHHHHHHHHH
TTSLLTGSDLVAVVPMAVATFHASMGLLHILPVPLPRKLDPYGIVTRLGRPPSASMTLFV
HHHHHCCCHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCHHHHHHCCCCCCCHHHHHH
DVLRAVVEEGGQ
HHHHHHHHCCCC
>Mature Secondary Structure
MIPPASTLRSRLKMQHLRLLLSIEERGSLRQAADALSLSQPAVTKMLQDMEALLGVTLFE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RHLRGLRPTRFGMAVTRYANLVFSDLANLHDELVSLETGRIGKVRIGAVMAPTPVLMAEV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEECCCHHHHHHH
IRRLKRDHPGLNMTVHVDTSDMLVPMLERDQLDLVLGRVPEGWDASHLTFEQLGDERLAV
HHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHCCCCEEEE
VVGCDHPLAKRTDPTFGELATYPWILQPRPSPMRALIDRSFEEAGVTAPQSTIETAAILM
EEECCCCCCCCCCCCHHHHHCCCEEECCCCCHHHHHHHCCHHHCCCCCCHHHHHHHHHHH
TTSLLTGSDLVAVVPMAVATFHASMGLLHILPVPLPRKLDPYGIVTRLGRPPSASMTLFV
HHHHHCCCHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCHHHHHHCCCCCCCHHHHHH
DVLRAVVEEGGQ
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]