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The map label for this gene is livM [H]

Identifier: 115351348

GI number: 115351348

Start: 1419940

End: 1421166

Strand: Direct

Name: livM [H]

Synonym: Bamb_1295

Alternate gene names: 115351348

Gene position: 1419940-1421166 (Clockwise)

Preceding gene: 115351347

Following gene: 115351349

Centisome position: 39.92

GC content: 75.22

Gene sequence:

>1227_bases
ATGGATAGCCGCAGGCGGGCCGGCGCGCTGCGCTGGGTGCTGTTCGCCGCGTGCGTCGCGCTACCCGCGTGGCTGTGGCC
GCATGGCGCGGTGCTCGGCTATCTCACGCAGACGGCCGCGCTCGTCGTGCTCGCGCTGTCGTACAACCTGCAGCTCGGCA
CGACCGGGCTGCTGTCGTTCGGTCATGCCGCGTTCGCGGGCCTCGGCGCGTTCGCCGCCGCGCACTGGTTCAATCGTGTC
GGCGGTCCGCTGCCGCTGTTGCCGCTCGTCGGCGGCGTGGCGGGCGCCGGCTTCGGGTTCATCGCCGGGTTGCTCGCGAC
ACGCCGCGCGGGCACCGTGTTCGCGATGATCACGCTCGGTCTCGCCGAATGCGTCGCGGCCGCCGCGTGGAGCGTGCCCG
CGTGGTTCGGCGGCCTCGGCGGCGTGCCGATCGACCGCGCGAGCGGCACGCCCTGGGGCGGCTGGCAGTTCGGCGCGCCG
GCGCAGGCCTACGCGGTGATCGCCGCGTGGTGCATCGTGTCGGCGCTGGCGATGCGCGCGCTGACGCGCACGCCGCTCGC
TCGGCTCGCGAACGCGGTGCGCGACAACCCCGCGCGCGTGGCTGCGCTCGGCACCGAGCCGCGCCGCGTGCGGCTCGCGA
TGGTCACCTGCGCGTCGTTCTTCGCGGGTATCGCCGGCACGCTGACGCTGATCGACGTCGAGATCGCGACGCCCGACAGC
CTGTCGATGGCGCGCTCGGCGACCGTGCTGATCGCCGCGGTGATCGGCGGCACCGGCACGTTCTTCGGGCCGGCGGCCGG
TGCCGTGGTGCTGACCGCGCTGAGCGTGGTCGTCGCCGGCGTGTCGCGTGCGTGGGCGCTGTATCTGGGCGTGCTGTTCG
TCGCGGTCGTCGTCGCGGCGCCCGGCGGGATCGCGGGCGTCGCACAGACGCTCGCGCATGCGTTGCGCCGCGACGCACCG
GCCGCCGAGCGCTGGCGCGTGCTGTGCGGCGTCGGCGCGTGCGTGTTCTGGGGCGTCGCGATCGTCTGCGCGGCCGAGCT
TGGCTATGCGTGGCGCTTCGCGCAGGACGACGGCGTGGGCACTGCATTCGGCGCGTGGGGCATCGATGCCGATGCGCCGG
CCGGCTGGGTCGTCGCGTGCGCGGCGGCCGGCGTCGGCATGCTGCTGTGGGGCTGGCGCGCGCGGCTGATGCACCCCGGG
CACGGCAAGCGGGAGGACGGGCGATGA

Upstream 100 bases:

>100_bases
GCGGCCGTATCGATCGCGCAACTGGCACCGCTGGTGCCGTATCTGCTGCTCGTCGCGGTGCTGGTCGCCCGTCCGCACGG
CTTGTTCGGCGAGCGTGTCG

Downstream 100 bases:

>100_bases
ACGGCAACGCGATCGCGCTGCACGGCATCGTGCAGCGCTTCGGCGCACAGACGGTGCTCGACGGTATCGAGCTGAGCGTC
TGCGCCGGCGAGCGTCACGC

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MDSRRRAGALRWVLFAACVALPAWLWPHGAVLGYLTQTAALVVLALSYNLQLGTTGLLSFGHAAFAGLGAFAAAHWFNRV
GGPLPLLPLVGGVAGAGFGFIAGLLATRRAGTVFAMITLGLAECVAAAAWSVPAWFGGLGGVPIDRASGTPWGGWQFGAP
AQAYAVIAAWCIVSALAMRALTRTPLARLANAVRDNPARVAALGTEPRRVRLAMVTCASFFAGIAGTLTLIDVEIATPDS
LSMARSATVLIAAVIGGTGTFFGPAAGAVVLTALSVVVAGVSRAWALYLGVLFVAVVVAAPGGIAGVAQTLAHALRRDAP
AAERWRVLCGVGACVFWGVAIVCAAELGYAWRFAQDDGVGTAFGAWGIDADAPAGWVVACAAAGVGMLLWGWRARLMHPG
HGKREDGR

Sequences:

>Translated_408_residues
MDSRRRAGALRWVLFAACVALPAWLWPHGAVLGYLTQTAALVVLALSYNLQLGTTGLLSFGHAAFAGLGAFAAAHWFNRV
GGPLPLLPLVGGVAGAGFGFIAGLLATRRAGTVFAMITLGLAECVAAAAWSVPAWFGGLGGVPIDRASGTPWGGWQFGAP
AQAYAVIAAWCIVSALAMRALTRTPLARLANAVRDNPARVAALGTEPRRVRLAMVTCASFFAGIAGTLTLIDVEIATPDS
LSMARSATVLIAAVIGGTGTFFGPAAGAVVLTALSVVVAGVSRAWALYLGVLFVAVVVAAPGGIAGVAQTLAHALRRDAP
AAERWRVLCGVGACVFWGVAIVCAAELGYAWRFAQDDGVGTAFGAWGIDADAPAGWVVACAAAGVGMLLWGWRARLMHPG
HGKREDGR
>Mature_408_residues
MDSRRRAGALRWVLFAACVALPAWLWPHGAVLGYLTQTAALVVLALSYNLQLGTTGLLSFGHAAFAGLGAFAAAHWFNRV
GGPLPLLPLVGGVAGAGFGFIAGLLATRRAGTVFAMITLGLAECVAAAAWSVPAWFGGLGGVPIDRASGTPWGGWQFGAP
AQAYAVIAAWCIVSALAMRALTRTPLARLANAVRDNPARVAALGTEPRRVRLAMVTCASFFAGIAGTLTLIDVEIATPDS
LSMARSATVLIAAVIGGTGTFFGPAAGAVVLTALSVVVAGVSRAWALYLGVLFVAVVVAAPGGIAGVAQTLAHALRRDAP
AAERWRVLCGVGACVFWGVAIVCAAELGYAWRFAQDDGVGTAFGAWGIDADAPAGWVVACAAAGVGMLLWGWRARLMHPG
HGKREDGR

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=291, Percent_Identity=29.2096219931272, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 41734; Mature: 41734

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSRRRAGALRWVLFAACVALPAWLWPHGAVLGYLTQTAALVVLALSYNLQLGTTGLLSF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHH
GHAAFAGLGAFAAAHWFNRVGGPLPLLPLVGGVAGAGFGFIAGLLATRRAGTVFAMITLG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LAECVAAAAWSVPAWFGGLGGVPIDRASGTPWGGWQFGAPAQAYAVIAAWCIVSALAMRA
HHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LTRTPLARLANAVRDNPARVAALGTEPRRVRLAMVTCASFFAGIAGTLTLIDVEIATPDS
HHHCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCC
LSMARSATVLIAAVIGGTGTFFGPAAGAVVLTALSVVVAGVSRAWALYLGVLFVAVVVAA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGGIAGVAQTLAHALRRDAPAAERWRVLCGVGACVFWGVAIVCAAELGYAWRFAQDDGVG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCC
TAFGAWGIDADAPAGWVVACAAAGVGMLLWGWRARLMHPGHGKREDGR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDSRRRAGALRWVLFAACVALPAWLWPHGAVLGYLTQTAALVVLALSYNLQLGTTGLLSF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHH
GHAAFAGLGAFAAAHWFNRVGGPLPLLPLVGGVAGAGFGFIAGLLATRRAGTVFAMITLG
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LAECVAAAAWSVPAWFGGLGGVPIDRASGTPWGGWQFGAPAQAYAVIAAWCIVSALAMRA
HHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LTRTPLARLANAVRDNPARVAALGTEPRRVRLAMVTCASFFAGIAGTLTLIDVEIATPDS
HHHCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCC
LSMARSATVLIAAVIGGTGTFFGPAAGAVVLTALSVVVAGVSRAWALYLGVLFVAVVVAA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGGIAGVAQTLAHALRRDAPAAERWRVLCGVGACVFWGVAIVCAAELGYAWRFAQDDGVG
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCC
TAFGAWGIDADAPAGWVVACAAAGVGMLLWGWRARLMHPGHGKREDGR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]