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The map label for this gene is pccB [H]

Identifier: 115351202

GI number: 115351202

Start: 1258858

End: 1259793

Strand: Direct

Name: pccB [H]

Synonym: Bamb_1149

Alternate gene names: 115351202

Gene position: 1258858-1259793 (Clockwise)

Preceding gene: 115351201

Following gene: 115351203

Centisome position: 35.4

GC content: 71.26

Gene sequence:

>936_bases
ATGACGACCGACATGATCCATGACACGCCCGCGTTCGTCGCGAACGGCGCGAGCTGGTACGAAGCGTCGGCGCGCCAGCG
CGTCGACGGGCTGCTCGACGCGGGCAGCTTCACGGAATTTCTCGGGCCGGGCGAACGCGTGACGAGCCCGCACCTGCCGC
TGTTCGACCTGCCGCAGCAGTTCGACGACGGGATGGTGGTCGGCCACGGCCGGCTCGACGGCAAGCCGGTGTTCGTCGCC
GCGCAGGAAGGCCGCTTCATGGGCGGCGCGTTCGGCGAAGTGCACGGCGCGAAGCTCACCGGGCTGCTGCGGGCGGCGCG
CGAACTCGGCACGCCGGTGCTGATCCTGTTCGATACGGGCGGCGTGCGGCTGCAGGAAGCGAACGCGGGCGAGCTCGCGA
TCGCCGAGATCATGCGGGCGCTCGTCGACGCGCGTGCAGCCGGCGTGCCGGTGATCGGACTGATCGGCGGGCGCTCCGGC
TGCTACGGCGGCGGTGGGCTGCTCGCCGCGTGCTGCTCGGCGCTCGCGGTGTCCGAGCAGGGGCGCATCAGCGTGTCGGG
CCCCGAGGTGATCGAGACCAATCGCGGTGTCGAGGAGTTCGACGCGAAGGATCGCGCGCTGATCTGGCGCACGATGGGCG
GCAAGCATCGGCGGCTGATCGGCGGCGCGGATCGTTACGTGGCCGACACGCCCGACGCGTTTCGCGCGGCGGCGCTCGCG
CTGCTCGAGCGTGCGCCGACATTCGACGTGGCGATGCTGCGCGCGGAGCAGGCGCGTCTCGAAGCCCGCGTCGAACGGTT
TGGTGGCTGCAAGGACGCTCTGGATGTGTGGCGCGCGCTCGGCGCGGACACGCCGGAAGCGATCCCCGGGATGCCCGACG
ACGAATTCGCGAAGCTCGCCGACCAACTGCAGGAGCCGCAGCATGACGCTCGATGA

Upstream 100 bases:

>100_bases
CGCCGGGCGGCCTGAAGCTGTCGATCAACGACGGCGGCGCGCGGCCCGACATGGTGTCGTTGCGGCTCGCGCAGGCCGTG
CGCGCGATCGAGGGGGACGC

Downstream 100 bases:

>100_bases
AGTCCTGACCTCGCTGTTTCCCAAAGGCCATTCGATTACGCGCAGCGGCGGCCTGCTGACGGGCCACGCGCTGCTGACCG
GCACGCGCGTCGACGTGATT

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTTDMIHDTPAFVANGASWYEASARQRVDGLLDAGSFTEFLGPGERVTSPHLPLFDLPQQFDDGMVVGHGRLDGKPVFVA
AQEGRFMGGAFGEVHGAKLTGLLRAARELGTPVLILFDTGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGRSG
CYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAALA
LLERAPTFDVAMLRAEQARLEARVERFGGCKDALDVWRALGADTPEAIPGMPDDEFAKLADQLQEPQHDAR

Sequences:

>Translated_311_residues
MTTDMIHDTPAFVANGASWYEASARQRVDGLLDAGSFTEFLGPGERVTSPHLPLFDLPQQFDDGMVVGHGRLDGKPVFVA
AQEGRFMGGAFGEVHGAKLTGLLRAARELGTPVLILFDTGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGRSG
CYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAALA
LLERAPTFDVAMLRAEQARLEARVERFGGCKDALDVWRALGADTPEAIPGMPDDEFAKLADQLQEPQHDAR
>Mature_310_residues
TTDMIHDTPAFVANGASWYEASARQRVDGLLDAGSFTEFLGPGERVTSPHLPLFDLPQQFDDGMVVGHGRLDGKPVFVAA
QEGRFMGGAFGEVHGAKLTGLLRAARELGTPVLILFDTGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGRSGC
YGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAALAL
LERAPTFDVAMLRAEQARLEARVERFGGCKDALDVWRALGADTPEAIPGMPDDEFAKLADQLQEPQHDAR

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=181, Percent_Identity=32.0441988950276, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788655, Length=184, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147359, Length=184, Percent_Identity=30.9782608695652, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25147362, Length=184, Percent_Identity=30.9782608695652, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 33037; Mature: 32906

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDMIHDTPAFVANGASWYEASARQRVDGLLDAGSFTEFLGPGERVTSPHLPLFDLPQQ
CCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCHH
FDDGMVVGHGRLDGKPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARELGTPVLILFDTG
CCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHCCCEEEEECCC
GVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGRSGCYGGGGLLAACCSALAVSEQ
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
GRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAALA
CEEEECCCCCEECCCCHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHH
LLERAPTFDVAMLRAEQARLEARVERFGGCKDALDVWRALGADTPEAIPGMPDDEFAKLA
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHCCCCCCHHHHHHH
DQLQEPQHDAR
HHHHCCCCCCC
>Mature Secondary Structure 
TTDMIHDTPAFVANGASWYEASARQRVDGLLDAGSFTEFLGPGERVTSPHLPLFDLPQQ
CCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCHH
FDDGMVVGHGRLDGKPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARELGTPVLILFDTG
CCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHHCCCEEEEECCC
GVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGRSGCYGGGGLLAACCSALAVSEQ
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
GRISVSGPEVIETNRGVEEFDAKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAALA
CEEEECCCCCEECCCCHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHH
LLERAPTFDVAMLRAEQARLEARVERFGGCKDALDVWRALGADTPEAIPGMPDDEFAKLA
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHCCCCCCHHHHHHH
DQLQEPQHDAR
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]