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The map label for this gene is otsA [H]

Identifier: 115351090

GI number: 115351090

Start: 1123431

End: 1124810

Strand: Direct

Name: otsA [H]

Synonym: Bamb_1036

Alternate gene names: 115351090

Gene position: 1123431-1124810 (Clockwise)

Preceding gene: 115351089

Following gene: 115351092

Centisome position: 31.59

GC content: 67.68

Gene sequence:

>1380_bases
ATGAGTCGACTCATCATCGTTTCGAACCGCGTCGCCCCGATTTCGGAAGGTGAACCGGCGGCGGGTGGCCTCGCGATCGG
CGTCTACGATGCGCTGAAGGAGACGGGCGGCATGTGGTTCGGCTGGAGCGGCGAGGTGGTCGCATCCGGTGCGCCGCAGA
TCCGCATCGAGGAGCGCGGCCCCGTGACGTTCGCGACCGTCGGGCTGTCGCGCCGCGATTACGACCAGTACTACCGCGGT
TTCTCGAACGCGACGCTGTGGCCCGCGTTCCATTACCGCGCCGACCTGATCCAGTACGACCGCCACGAGTTCGACGGCTA
CCGCCGCGTGAACGTGTGGCTCGCGCAGCAGCTCGTGCCGCTGCTGCAGGACGACGACGTGATCTGGGTGCACGACTATC
ACCTGATCCCGTTCGCGCGTGCGCTGCGGGAGGCCGGCGTGAAGAACCGCATCGGCTTTTTCCTGCACATTCCGTTTCCG
GCCGCGCAGGTGCTCGTCAACGTGCCGCCGCATCGCGAGCTTGTCGAGTCGCTGTGCGCGTTCGACTTGCTCGGCTTCCA
GACCGAGCCCGACCTGCGCGCGTTCTGCGACTACATCGAGTTCGAGGCGGGCGGCGAAGTGGCGCGCGAAGGGCACACGG
TGCGCGTGAGCGCGTTCGGCAACACGCTGCGCGCGGCCGCCTATCCGATCGGCGTGTATCCGGACGAGATCGCGTCGCTC
GCGCAGGCGGCCGAGAACGGCAAGGCCGTGCGCACGCTGGCGACGTCGCTGCGCGGGCGCCAGTTGATCATGAGCGTCGA
CCGGCTCGATTATTCGAAAGGGCTCGTCGAGCGGTTCCGCGCGTTCGAGAAACTGCTGGAGCACCAGACGTCGATTCGCA
ACCGCGTGTCGTTCCTGCAGATCGCGCCATCGACGCGCGCCGACCTGCGCGCGTACCAGGACATCCGCCTGCAGCTCGAA
GCGGAGTCGGGGCGCATCAACGGCCGCTACGCGGAACTCGACTGGGCGCCGATCCTCTACATTCACCGCCAGTACGACCG
GCAGGTGCTGGCCGCGCTGTACCGGCTGGCGCGCGTGGGTTTCGTCACGCCGCTGCGCGACGGCATGAACCTCGTCGCGA
AGGAGTACGTGTCCGCGCAGAATCCGGACGATCCGGGCGTGCTGGTGCTGTCGCGCTTCGCGGGCGCGGCGCGTGAGCTG
ACGGGCGCGCTGATCGTGAATCCGATCGACATCGACGGAATGGCCGATGCGTTGTCGCAGGCGCTGACGATGCCGCTCGC
CGAGCGGCGCGCGCGTTATGCGGACATGATCGCGCAGCTGCGCGAGAACAACGTGTCGGTGTGGCGCGACAACTTCCTGC
GCGACCTGCAGCGCGTGTAG

Upstream 100 bases:

>100_bases
AGGTCGGCGCGGGCGAGACGTCGGCCCGCATGCGGCTCGACTCGGTCGACGCGCTGCACGCGCAGATTGCCCGCTGGCTT
GGCGCGGAGCAGCGGGGCGC

Downstream 100 bases:

>100_bases
CCGGCGCGCCGCGCGGCGGATGCCGCGCGATGCCATGAAAAAAGCCGCCGTGCGTCGCACAGGCGGCTTTCTTATCGGTT
GCGTGCCCGTGGCGTCAGGC

Product: alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRIEERGPVTFATVGLSRRDYDQYYRG
FSNATLWPAFHYRADLIQYDRHEFDGYRRVNVWLAQQLVPLLQDDDVIWVHDYHLIPFARALREAGVKNRIGFFLHIPFP
AAQVLVNVPPHRELVESLCAFDLLGFQTEPDLRAFCDYIEFEAGGEVAREGHTVRVSAFGNTLRAAAYPIGVYPDEIASL
AQAAENGKAVRTLATSLRGRQLIMSVDRLDYSKGLVERFRAFEKLLEHQTSIRNRVSFLQIAPSTRADLRAYQDIRLQLE
AESGRINGRYAELDWAPILYIHRQYDRQVLAALYRLARVGFVTPLRDGMNLVAKEYVSAQNPDDPGVLVLSRFAGAAREL
TGALIVNPIDIDGMADALSQALTMPLAERRARYADMIAQLRENNVSVWRDNFLRDLQRV

Sequences:

>Translated_459_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRIEERGPVTFATVGLSRRDYDQYYRG
FSNATLWPAFHYRADLIQYDRHEFDGYRRVNVWLAQQLVPLLQDDDVIWVHDYHLIPFARALREAGVKNRIGFFLHIPFP
AAQVLVNVPPHRELVESLCAFDLLGFQTEPDLRAFCDYIEFEAGGEVAREGHTVRVSAFGNTLRAAAYPIGVYPDEIASL
AQAAENGKAVRTLATSLRGRQLIMSVDRLDYSKGLVERFRAFEKLLEHQTSIRNRVSFLQIAPSTRADLRAYQDIRLQLE
AESGRINGRYAELDWAPILYIHRQYDRQVLAALYRLARVGFVTPLRDGMNLVAKEYVSAQNPDDPGVLVLSRFAGAAREL
TGALIVNPIDIDGMADALSQALTMPLAERRARYADMIAQLRENNVSVWRDNFLRDLQRV
>Mature_458_residues
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRIEERGPVTFATVGLSRRDYDQYYRGF
SNATLWPAFHYRADLIQYDRHEFDGYRRVNVWLAQQLVPLLQDDDVIWVHDYHLIPFARALREAGVKNRIGFFLHIPFPA
AQVLVNVPPHRELVESLCAFDLLGFQTEPDLRAFCDYIEFEAGGEVAREGHTVRVSAFGNTLRAAAYPIGVYPDEIASLA
QAAENGKAVRTLATSLRGRQLIMSVDRLDYSKGLVERFRAFEKLLEHQTSIRNRVSFLQIAPSTRADLRAYQDIRLQLEA
ESGRINGRYAELDWAPILYIHRQYDRQVLAALYRLARVGFVTPLRDGMNLVAKEYVSAQNPDDPGVLVLSRFAGAARELT
GALIVNPIDIDGMADALSQALTMPLAERRARYADMIAQLRENNVSVWRDNFLRDLQRV

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=460, Percent_Identity=53.0434782608696, Blast_Score=480, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI115533558, Length=429, Percent_Identity=28.6713286713287, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI115533560, Length=429, Percent_Identity=28.6713286713287, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71987012, Length=428, Percent_Identity=28.2710280373832, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319602, Length=470, Percent_Identity=31.2765957446809, Blast_Score=265, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6323537, Length=435, Percent_Identity=25.7471264367816, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320279, Length=402, Percent_Identity=25.8706467661692, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6323917, Length=380, Percent_Identity=26.5789473684211, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920676, Length=486, Percent_Identity=35.59670781893, Blast_Score=273, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 51666; Mature: 51535

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRIEERG
CCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCEEECCCCEEEEECCC
PVTFATVGLSRRDYDQYYRGFSNATLWPAFHYRADLIQYDRHEFDGYRRVNVWLAQQLVP
CEEEEEECCCCCCHHHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
LLQDDDVIWVHDYHLIPFARALREAGVKNRIGFFLHIPFPAAQVLVNVPPHRELVESLCA
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEEECCCHHHHHHHHHH
FDLLGFQTEPDLRAFCDYIEFEAGGEVAREGHTVRVSAFGNTLRAAAYPIGVYPDEIASL
HHHHCCCCCCCHHHHHHHHHHCCCCCHHHCCCEEEEEECCCHHHHHHCCCCCCHHHHHHH
AQAAENGKAVRTLATSLRGRQLIMSVDRLDYSKGLVERFRAFEKLLEHQTSIRNRVSFLQ
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IAPSTRADLRAYQDIRLQLEAESGRINGRYAELDWAPILYIHRQYDRQVLAALYRLARVG
ECCCCHHHHHHHEEEEEEEEECCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHC
FVTPLRDGMNLVAKEYVSAQNPDDPGVLVLSRFAGAARELTGALIVNPIDIDGMADALSQ
CCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCHHHHHCCEEEEECCCCCHHHHHHHH
ALTMPLAERRARYADMIAQLRENNVSVWRDNFLRDLQRV
HHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRIEERG
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCEEECCCCEEEEECCC
PVTFATVGLSRRDYDQYYRGFSNATLWPAFHYRADLIQYDRHEFDGYRRVNVWLAQQLVP
CEEEEEECCCCCCHHHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
LLQDDDVIWVHDYHLIPFARALREAGVKNRIGFFLHIPFPAAQVLVNVPPHRELVESLCA
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEEECCCHHHHHHHHHH
FDLLGFQTEPDLRAFCDYIEFEAGGEVAREGHTVRVSAFGNTLRAAAYPIGVYPDEIASL
HHHHCCCCCCCHHHHHHHHHHCCCCCHHHCCCEEEEEECCCHHHHHHCCCCCCHHHHHHH
AQAAENGKAVRTLATSLRGRQLIMSVDRLDYSKGLVERFRAFEKLLEHQTSIRNRVSFLQ
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
IAPSTRADLRAYQDIRLQLEAESGRINGRYAELDWAPILYIHRQYDRQVLAALYRLARVG
ECCCCHHHHHHHEEEEEEEEECCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHC
FVTPLRDGMNLVAKEYVSAQNPDDPGVLVLSRFAGAARELTGALIVNPIDIDGMADALSQ
CCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHCCHHHHHCCEEEEECCCCCHHHHHHHH
ALTMPLAERRARYADMIAQLRENNVSVWRDNFLRDLQRV
HHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA