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The map label for this gene is map [H]

Identifier: 115351081

GI number: 115351081

Start: 1116295

End: 1117101

Strand: Direct

Name: map [H]

Synonym: Bamb_1027

Alternate gene names: 115351081

Gene position: 1116295-1117101 (Clockwise)

Preceding gene: 115351080

Following gene: 115351084

Centisome position: 31.39

GC content: 67.16

Gene sequence:

>807_bases
ATGGCGAAGCGAGAAATCCCGATCCGCGGTGCCGCGGAAATCGACAAGTCGCGCGAGGCCGCGAAGCTCGCATCGCGCGT
GCTGACGATGATCACCGAGCACGTGAAGCCGGGCGTCACCACGGACGAACTGGACGCCCGCTGCCGCGAATACATCGTCG
ACGAACTCGGCGCGATCCCGGCGAACATCGGCTATCACGGTTATCCGAAAACCCTGTGCACGTCGGTCAACCACGTGGTC
TGTCACGGTATTCCGTCGTCGCGGCCGATGCGCGACGGCGACATCGTGAATCTCGACATCGCGGTGATCAAGGACGGCTG
GTTCGGCGACACGAGCCGCATGTACTTCGTCGGCGAGCCGGGTGAACTGGCGCGGCGCCTCGTCGCGACGACCTACGAGG
CGATGCATGCGGGCATCCGCGCGGTGCGTCCGGGCGCGACGCTCGGCGACGTCGGCTATGCGATCCAGCAGGTCGCGCAT
CGCGAAGGGTTCAGCGTGGTTCGCGAGTACTGCGGGCACGGGATCGGCGACGTGTACCACGACGAGCCGCAGGTGCTGCA
CTATGGCCGCCCGGGCACCGGCGTGCCGCTGCGGCCGGGGATGATCTTCACGATCGAGCCGATGCTGAATGCGGGCAAGC
GCGATACGCGCGTGCTGGCGGACGGCTGGACGGTCGTCACGCAAGACCATTCGCTGTCCGCGCAATGGGAGCACATGGTC
GTGGTGACGGAGCAGGGCGTCGAGATCCTGTCGGACGACGTGAAGCCGCAGGCGTTCGCGGCGCTCTCCGGCACGCACGC
GGCCTGA

Upstream 100 bases:

>100_bases
CCTACGGCGATATCTGCCGAATGCTGATCGAGATCGAAGCGCGCGGCGGCGACGCGGGGCCGACCGAGTCGGTGGCGCGC
GACATCGAGCAGGTGGCGTA

Downstream 100 bases:

>100_bases
CGCGCGGCAGCCCGCACTTAAAGGCGCAATCGAAACGGGCCCCGTCGTGGGGCCCGTGTCATTCATTGGCAGTCGCGCGG
GACGGTCAGCAGGCCGCCGT

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAKREIPIRGAAEIDKSREAAKLASRVLTMITEHVKPGVTTDELDARCREYIVDELGAIPANIGYHGYPKTLCTSVNHVV
CHGIPSSRPMRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPGELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAH
REGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTQDHSLSAQWEHMV
VVTEQGVEILSDDVKPQAFAALSGTHAA

Sequences:

>Translated_268_residues
MAKREIPIRGAAEIDKSREAAKLASRVLTMITEHVKPGVTTDELDARCREYIVDELGAIPANIGYHGYPKTLCTSVNHVV
CHGIPSSRPMRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPGELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAH
REGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTQDHSLSAQWEHMV
VVTEQGVEILSDDVKPQAFAALSGTHAA
>Mature_267_residues
AKREIPIRGAAEIDKSREAAKLASRVLTMITEHVKPGVTTDELDARCREYIVDELGAIPANIGYHGYPKTLCTSVNHVVC
HGIPSSRPMRDGDIVNLDIAVIKDGWFGDTSRMYFVGEPGELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAHR
EGFSVVREYCGHGIGDVYHDEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTQDHSLSAQWEHMVV
VTEQGVEILSDDVKPQAFAALSGTHAA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=261, Percent_Identity=41.3793103448276, Blast_Score=216, Evalue=1e-56,
Organism=Homo sapiens, GI40385867, Length=246, Percent_Identity=39.8373983739837, Blast_Score=206, Evalue=2e-53,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=55.6862745098039, Blast_Score=298, Evalue=2e-82,
Organism=Escherichia coli, GI1788728, Length=250, Percent_Identity=26, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789275, Length=285, Percent_Identity=25.9649122807018, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=39.4422310756972, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323273, Length=249, Percent_Identity=42.570281124498, Blast_Score=218, Evalue=7e-58,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=42.1052631578947, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=38.6178861788618, Blast_Score=191, Evalue=5e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29223; Mature: 29091

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKREIPIRGAAEIDKSREAAKLASRVLTMITEHVKPGVTTDELDARCREYIVDELGAIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
ANIGYHGYPKTLCTSVNHVVCHGIPSSRPMRDGDIVNLDIAVIKDGWFGDTSRMYFVGEP
CCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEECCC
GELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAHREGFSVVREYCGHGIGDVYH
HHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
DEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTQDHSLSAQWEHMV
CCCCEEEECCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEE
VVTEQGVEILSDDVKPQAFAALSGTHAA
EEECCCHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
AKREIPIRGAAEIDKSREAAKLASRVLTMITEHVKPGVTTDELDARCREYIVDELGAIP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
ANIGYHGYPKTLCTSVNHVVCHGIPSSRPMRDGDIVNLDIAVIKDGWFGDTSRMYFVGEP
CCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEECCC
GELARRLVATTYEAMHAGIRAVRPGATLGDVGYAIQQVAHREGFSVVREYCGHGIGDVYH
HHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCC
DEPQVLHYGRPGTGVPLRPGMIFTIEPMLNAGKRDTRVLADGWTVVTQDHSLSAQWEHMV
CCCCEEEECCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEE
VVTEQGVEILSDDVKPQAFAALSGTHAA
EEECCCHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]