Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 115350995

GI number: 115350995

Start: 1034040

End: 1034588

Strand: Direct

Name: lrp [H]

Synonym: Bamb_0941

Alternate gene names: 115350995

Gene position: 1034040-1034588 (Clockwise)

Preceding gene: 115350993

Following gene: 115350996

Centisome position: 29.07

GC content: 58.65

Gene sequence:

>549_bases
ATGGTATTGTCGAATGTGCAGGTTTTGTTATCGTATTTTTCAGGTTTTCAGAATAAACAAATGAGAACGCAACGCCAGCC
AGTACGCTCGCTCGACAAGCTCGACCGGCGCATCCTCAAACTGCTGCAGGACGACGGCCGGATGGCGATGAAGGACCTCG
CGGAACAGGTCGGCCTGACCGTGACGCCATGCATCGAGCGCGTGCGGCGCATGGAGCGCGACGGGGTCATCACCGGCTAT
CACGCACGCGTCGATCCGGGCCAGCTCGGTGCCGCGCTGCTGGTGTTCGTCGAGATCACGCTTGGCCACAAGGGCGGCAA
CATGTTCGAGCAGTTCCGTCGCGAAGTGATGAAGATCGACGAGGTGCTCGAATGCCATCTCGTGTCCGGCGACTTCGACT
ATCTGATCAAGGCGCGGATCGGTGAAATGGCCGACTATCGCAAGCTGCTCGGCGACATCCTGCTGCAACTGCCCGGCGCG
GTGCAGTCGAAGAGCTATGTCGTGATGGAGGAAATCAAGGAAACGCTGACGATTTCGGTCGGCGAATGA

Upstream 100 bases:

>100_bases
AACGACGACTCGCATAGCTGCTCCAGATGGAAGGGATCAGGTCGAGGCCGGGCGCACCTGCGTCTCCGTGTAACCTCTAG
CTGATCTAGTTTTTTGAGCT

Downstream 100 bases:

>100_bases
CCGCTGCCGCTGCCGCGGCCGGTTGCCGGCGCCGCTGTCGGGCCCCTTATCTCGCCCTTGGCATGCTGCACCCAATACTG
TATAAATATACAGTATTGGG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MVLSNVQVLLSYFSGFQNKQMRTQRQPVRSLDKLDRRILKLLQDDGRMAMKDLAEQVGLTVTPCIERVRRMERDGVITGY
HARVDPGQLGAALLVFVEITLGHKGGNMFEQFRREVMKIDEVLECHLVSGDFDYLIKARIGEMADYRKLLGDILLQLPGA
VQSKSYVVMEEIKETLTISVGE

Sequences:

>Translated_182_residues
MVLSNVQVLLSYFSGFQNKQMRTQRQPVRSLDKLDRRILKLLQDDGRMAMKDLAEQVGLTVTPCIERVRRMERDGVITGY
HARVDPGQLGAALLVFVEITLGHKGGNMFEQFRREVMKIDEVLECHLVSGDFDYLIKARIGEMADYRKLLGDILLQLPGA
VQSKSYVVMEEIKETLTISVGE
>Mature_182_residues
MVLSNVQVLLSYFSGFQNKQMRTQRQPVRSLDKLDRRILKLLQDDGRMAMKDLAEQVGLTVTPCIERVRRMERDGVITGY
HARVDPGQLGAALLVFVEITLGHKGGNMFEQFRREVMKIDEVLECHLVSGDFDYLIKARIGEMADYRKLLGDILLQLPGA
VQSKSYVVMEEIKETLTISVGE

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=153, Percent_Identity=54.2483660130719, Blast_Score=181, Evalue=2e-47,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=35.3333333333333, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 20688; Mature: 20688

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSNVQVLLSYFSGFQNKQMRTQRQPVRSLDKLDRRILKLLQDDGRMAMKDLAEQVGLT
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
VTPCIERVRRMERDGVITGYHARVDPGQLGAALLVFVEITLGHKGGNMFEQFRREVMKID
HHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EVLECHLVSGDFDYLIKARIGEMADYRKLLGDILLQLPGAVQSKSYVVMEEIKETLTISV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
GE
CC
>Mature Secondary Structure
MVLSNVQVLLSYFSGFQNKQMRTQRQPVRSLDKLDRRILKLLQDDGRMAMKDLAEQVGLT
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
VTPCIERVRRMERDGVITGYHARVDPGQLGAALLVFVEITLGHKGGNMFEQFRREVMKID
HHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EVLECHLVSGDFDYLIKARIGEMADYRKLLGDILLQLPGAVQSKSYVVMEEIKETLTISV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
GE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]