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The map label for this gene is capD [H]

Identifier: 115350819

GI number: 115350819

Start: 850042

End: 851934

Strand: Direct

Name: capD [H]

Synonym: Bamb_0765

Alternate gene names: 115350819

Gene position: 850042-851934 (Clockwise)

Preceding gene: 115350818

Following gene: 115350820

Centisome position: 23.9

GC content: 63.5

Gene sequence:

>1893_bases
ATGTTCCGATCCAAAGCATCGTGGCTTTCACTGAGTGCTTTCCTGTTCGACCTGACAGCGGTTGTCGCGTCGTGGTTGTT
TGCTTACCTCGTTCGTTTCAACGGCAGTATTCCGGCTGATTTTCTCGGCGGCGCACTGCAGGCACTCGTCTGGGCGTTGC
CGGTCTACGCGCTGATGTTCCATCTGTTCGGCCTGTACCGCGGCCTGTGGGTGTTCGCGAGCCTGCCGGACCTGATGCGC
ATTTCGAAGGCGGTCGGAGGCGGCGGTGTGATCGTGATGATCGGTGCGGTGATGTTCCAGCCGTCCCCGATCATTCCGCG
CTCGGTGCTGATCGTGTCGCCGCTGATGTTGTTCCTCGCGATGGGCGGCGCTCGCGCGCTTTACCGCGCGACAAAGGAGT
TCTACCTGTATGGCGGGCTGGTCGGGCAGGGCAAGCCGGTGCTGGTGCTCGGGGCCGGCACGGCAGGCGCGAGCCTCGCG
CGTGAGCTGTCGCGTTCGGGTGAGTGGCGTCTGGTTGGCCTGCTCGACGACGATGTCACAAAGCAAGGACGCGAGATCTA
TGGCTACAAGGTGCTCGGTTCGTTCAACGACCTGAAGCACTGGACCGACGCGATGAAGATCGAATACGCGATCATCGCGA
TTCCGTCGGCGTCGGTCGAAACGCAGCGGCGCGTCGCGACGCTGTGCGTGCGGGCGGGCGTGAAGGCGATGGTACTGCCG
TCGCTGACCGCGTTGATGCCGGGGCAGGGGTTCCTGTCGCAAGTGCGCAATATCGACCTCGAGGATCTGCTTGGCCGCGA
CGCGGTGACGATCGACACGCCGCACGTCGAGGCGTTGCTGCGCGGTCGCGTCGTGATGGTGACGGGCGCTGGCGGTTCAA
TCGGTTCGGAGCTGTGCCGGCAGATCCTTCGTTTCGCGCCGGCGCAGCTCGTTGCGTTCGACCTGTCCGAATACGCGATG
TACCGGCTTGCCGAAGAGTTGCGCGAACGCTTTCCGGATCAGCCGGTGGTGCCGATCATTGGCGATGCCAAGGATTCGCT
GCTGCTCGATCAGGTGATGTCGCGTCATGCGCCGCACATCGTGTTCCATGCGGCCGCGTACAAACACGTGCCGCTGATGG
AGGAACACAACGCGTGGCAGGCGCTACGCAACAATGTACTCGGCACGTACCGCGTTGCATGCGCCGCGATCCGCCACGAC
GTGCGCCATTTCGTGCTCATCTCTACCGACAAGGCCGTCAACCCGACCAACGTGATGGGCGCGAGCAAGCGTTTGGCTGA
GATGGTCTGCCAGGCGCTGCAGCAGACGAGCGGCGGTACGCAGTTCGAGACCGTGCGCTTCGGCAACGTGCTCGGCAGCG
CCGGTAGCGTGATTCCGAAGTTCCAGCAGCAGATCGCCAAGGGTGGCCCGGTGACGGTCACGCACCCGGAAATCACGCGG
TTCTTCATGACGATTCCGGAAGCGTCGCAGCTCGTGCTGCAGGCGTCGAGCATGGGGCATGGGGGCGAAATCTTTATTCT
CGAGATGGGGCAGCCGGTCAGGATCGTTGATCTCGCTCGCGATCTGATCCGCCTGTACGGCTTCTCGGAAGGGCAGATCC
GGATCGACTTTACGGGGCTGAGGCCCGGCGAGAAGCTCTACGAGGAACTCCTCGCGGACGACGAGACGACCACGCGCACA
CCGCATCCGAAGCTGCGGATCGCACGCGCGCGCGAAGTGCCGGACCACCTCCTTGACGAACTGCTGCCGTGGCTGATGCA
GCGTCGTGTATTGAGCGACGACGAAGTGCGTCGGGATCTGCGGCGCTGGGTGCCCGAATACCAGACGGCTGCGAGTCCCG
CCCTTCAAACCGTACCCACGTTGTTCCCCTCGAAGTCGGCGGCGCGAGATTAG

Upstream 100 bases:

>100_bases
CGCGTGGTACGGCGTCCTGGCATGTCTCGGATTGGTGATTGACATGCGCTGGCGCCGGTTCCAGTCGGCAGCCGAAAACA
ACTCCTGAGGTTTCCCGCCG

Downstream 100 bases:

>100_bases
CGGCCGCCCCATGCCGGTGCGCGACCGTCAGTCATGGCAGGTCGCCACGGTCACCACGGCTTCGCATCGAATCTGCATTC
CTCATCAAGCAATGACAGCG

Product: polysaccharide biosynthesis protein CapD

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MFRSKASWLSLSAFLFDLTAVVASWLFAYLVRFNGSIPADFLGGALQALVWALPVYALMFHLFGLYRGLWVFASLPDLMR
ISKAVGGGGVIVMIGAVMFQPSPIIPRSVLIVSPLMLFLAMGGARALYRATKEFYLYGGLVGQGKPVLVLGAGTAGASLA
RELSRSGEWRLVGLLDDDVTKQGREIYGYKVLGSFNDLKHWTDAMKIEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCRQILRFAPAQLVAFDLSEYAM
YRLAEELRERFPDQPVVPIIGDAKDSLLLDQVMSRHAPHIVFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVACAAIRHD
VRHFVLISTDKAVNPTNVMGASKRLAEMVCQALQQTSGGTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILEMGQPVRIVDLARDLIRLYGFSEGQIRIDFTGLRPGEKLYEELLADDETTTRT
PHPKLRIARAREVPDHLLDELLPWLMQRRVLSDDEVRRDLRRWVPEYQTAASPALQTVPTLFPSKSAARD

Sequences:

>Translated_630_residues
MFRSKASWLSLSAFLFDLTAVVASWLFAYLVRFNGSIPADFLGGALQALVWALPVYALMFHLFGLYRGLWVFASLPDLMR
ISKAVGGGGVIVMIGAVMFQPSPIIPRSVLIVSPLMLFLAMGGARALYRATKEFYLYGGLVGQGKPVLVLGAGTAGASLA
RELSRSGEWRLVGLLDDDVTKQGREIYGYKVLGSFNDLKHWTDAMKIEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCRQILRFAPAQLVAFDLSEYAM
YRLAEELRERFPDQPVVPIIGDAKDSLLLDQVMSRHAPHIVFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVACAAIRHD
VRHFVLISTDKAVNPTNVMGASKRLAEMVCQALQQTSGGTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILEMGQPVRIVDLARDLIRLYGFSEGQIRIDFTGLRPGEKLYEELLADDETTTRT
PHPKLRIARAREVPDHLLDELLPWLMQRRVLSDDEVRRDLRRWVPEYQTAASPALQTVPTLFPSKSAARD
>Mature_630_residues
MFRSKASWLSLSAFLFDLTAVVASWLFAYLVRFNGSIPADFLGGALQALVWALPVYALMFHLFGLYRGLWVFASLPDLMR
ISKAVGGGGVIVMIGAVMFQPSPIIPRSVLIVSPLMLFLAMGGARALYRATKEFYLYGGLVGQGKPVLVLGAGTAGASLA
RELSRSGEWRLVGLLDDDVTKQGREIYGYKVLGSFNDLKHWTDAMKIEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCRQILRFAPAQLVAFDLSEYAM
YRLAEELRERFPDQPVVPIIGDAKDSLLLDQVMSRHAPHIVFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVACAAIRHD
VRHFVLISTDKAVNPTNVMGASKRLAEMVCQALQQTSGGTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
FFMTIPEASQLVLQASSMGHGGEIFILEMGQPVRIVDLARDLIRLYGFSEGQIRIDFTGLRPGEKLYEELLADDETTTRT
PHPKLRIARAREVPDHLLDELLPWLMQRRVLSDDEVRRDLRRWVPEYQTAASPALQTVPTLFPSKSAARD

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 69433; Mature: 69433

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSKASWLSLSAFLFDLTAVVASWLFAYLVRFNGSIPADFLGGALQALVWALPVYALMF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
HLFGLYRGLWVFASLPDLMRISKAVGGGGVIVMIGAVMFQPSPIIPRSVLIVSPLMLFLA
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEHHHHCCCCCCCCHHHHHHHHHHHHHH
MGGARALYRATKEFYLYGGLVGQGKPVLVLGAGTAGASLARELSRSGEWRLVGLLDDDVT
CCCHHHHHHHHHHHEEECCEECCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHH
KQGREIYGYKVLGSFNDLKHWTDAMKIEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
HCCCCEEEEEEECCCHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCR
HHHHHCCCHHHHHHHHCCCHHHHCCCCCEEECCHHHHHHHCCCEEEEECCCCCHHHHHHH
QILRFAPAQLVAFDLSEYAMYRLAEELRERFPDQPVVPIIGDAKDSLLLDQVMSRHAPHI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCEE
VFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVACAAIRHDVRHFVLISTDKAVNPTNVMG
EEEHHHHHCCCCHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHH
ASKRLAEMVCQALQQTSGGTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHCCCCEEEECHHHHH
FFMTIPEASQLVLQASSMGHGGEIFILEMGQPVRIVDLARDLIRLYGFSEGQIRIDFTGL
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
RPGEKLYEELLADDETTTRTPHPKLRIARAREVPDHLLDELLPWLMQRRVLSDDEVRRDL
CCHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
RRWVPEYQTAASPALQTVPTLFPSKSAARD
HHHCCHHHHHCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFRSKASWLSLSAFLFDLTAVVASWLFAYLVRFNGSIPADFLGGALQALVWALPVYALMF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
HLFGLYRGLWVFASLPDLMRISKAVGGGGVIVMIGAVMFQPSPIIPRSVLIVSPLMLFLA
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEHHHHCCCCCCCCHHHHHHHHHHHHHH
MGGARALYRATKEFYLYGGLVGQGKPVLVLGAGTAGASLARELSRSGEWRLVGLLDDDVT
CCCHHHHHHHHHHHEEECCEECCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHH
KQGREIYGYKVLGSFNDLKHWTDAMKIEYAIIAIPSASVETQRRVATLCVRAGVKAMVLP
HCCCCEEEEEEECCCHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHH
SLTALMPGQGFLSQVRNIDLEDLLGRDAVTIDTPHVEALLRGRVVMVTGAGGSIGSELCR
HHHHHCCCHHHHHHHHCCCHHHHCCCCCEEECCHHHHHHHCCCEEEEECCCCCHHHHHHH
QILRFAPAQLVAFDLSEYAMYRLAEELRERFPDQPVVPIIGDAKDSLLLDQVMSRHAPHI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHCCCCEE
VFHAAAYKHVPLMEEHNAWQALRNNVLGTYRVACAAIRHDVRHFVLISTDKAVNPTNVMG
EEEHHHHHCCCCHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHH
ASKRLAEMVCQALQQTSGGTQFETVRFGNVLGSAGSVIPKFQQQIAKGGPVTVTHPEITR
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHCCCCEEEECHHHHH
FFMTIPEASQLVLQASSMGHGGEIFILEMGQPVRIVDLARDLIRLYGFSEGQIRIDFTGL
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECC
RPGEKLYEELLADDETTTRTPHPKLRIARAREVPDHLLDELLPWLMQRRVLSDDEVRRDL
CCHHHHHHHHHCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
RRWVPEYQTAASPALQTVPTLFPSKSAARD
HHHCCHHHHHCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]