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The map label for this gene is mraY

Identifier: 115350514

GI number: 115350514

Start: 521330

End: 522499

Strand: Direct

Name: mraY

Synonym: Bamb_0460

Alternate gene names: 115350514

Gene position: 521330-522499 (Clockwise)

Preceding gene: 115350513

Following gene: 115350515

Centisome position: 14.66

GC content: 62.82

Gene sequence:

>1170_bases
ATGCTGCTGGCGCTGGCGCAATGGCTGCAGGGCGACGCAAGCTTTTTGCGCTTGTTCACGTACCTGACGTTCCGTGCGGT
GATGGCTACCATCACCGCGCTCGGGATCGGGCTCGTGTGCGGACCGTGGGTGATCCGCAAGCTGACGCAAATGAAGGTGG
GGCAGGCCGTGCGCAAGGACGGCCCGCAGAGCCACCTCGTGAAGTCCGGCACGCCGACGATGGGCGGCGTGCTGATCCTG
ATTGGCATCGCGGTCGCGACGCTGCTGTGGGGCGACCTGACCAACCGTTTCATCTGGATCGTGATGCTCGTCACGTTCGG
TTTCGGCGTGATCGGCTGGGTCGATGACTATCGCAAGGTCGTCTACAAGGATCCGCGCGGGATGTCGTCGCGCGAAAAGT
ATTTCTGGCAATCGGTGATCGGGCTGTTCGCGGCGGTCTACCTGGCATTCAGCGTGTCCGAGGCGAACAACGTGCGCGTG
TTCGACCTGTTCATGGCGTGGGTGCGCAGCGGCCTGTCGATGGGGCTGCCCGCGCGTGCCGACCTGATGCTGCCGTTCTT
GAAATCGATCAGCTACCCGCTGGGCGTGTGGGGCTTCATCGTGCTGACCTACTTCGTGATCGTCGGCGCGAGCAACGCGG
TGAACCTCACTGACGGCCTCGACGGCCTCGTGATCATGCCGGTCGTGCTGGTCGGTGGGTCGCTCGGCGTGTTCGCGTAT
GTGATGGGGAGTTCGGTCTATTCGAAATACCTGTTGTTCCCGCACATTCCGGGCGCGGGCGAACTGCTGATCTTCTGTTC
GGCGATGGGGGGGGCAGGGCTCGCGTTCCTCTGGTACAACACGCACCCCGCGCAGGTGTTCATGGGCGACGTCGGCGCGC
TGGCGCTCGGCGGCGCGCTCGGCACGGTCGCGGTGATCGTGCGCCAGGAAATCGTGCTGTTCATCATGGGTGGCATCTTC
GTCGCGGAAACCTTGTCGGTGATGCTGCAGGTGTCGTGGTTCAAGTACACGAAGAAGCGTTACGGCGAAGGGCGGCGCCT
GCTGAAGATGGCGCCGCTGCATCACCATTTCGAATTGTCCGGCTGGAAGGAAACGCAGGTGGTGGTGCGTTTCTGGATCA
TCACGCTGATGCTGTGCCTGTTCGGTCTGTCCACCCTCAAGTTGCGGTAA

Upstream 100 bases:

>100_bases
GGCTCGCGGTACATGAAGATGGAGCGCGTGGTCGACGCGCTGACGAACCAATCCGCGGCGGGCACGGTGCCCGCCGCACA
CTGAGTAGAAGGAAGGAAGC

Downstream 100 bases:

>100_bases
AGGAAAGGTAAAAGGATGTCTGGCGAGATGTTTGGAGATCGGCAGCGGCCGATGGTGCTCGTACTGGGGCTCGGGGAATC
GGGCCTCGCGATCGCGCGAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQSHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGGSLGVFAY
VMGSSVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR

Sequences:

>Translated_389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQSHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGGSLGVFAY
VMGSSVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
>Mature_389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQSHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGGSLGVFAY
VMGSSVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=389, Percent_Identity=52.1850899742931, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_BURA4 (B1YSS1)

Other databases:

- EMBL:   CP001025
- RefSeq:   YP_001807198.1
- GeneID:   6179099
- GenomeReviews:   CP001025_GR
- KEGG:   bac:BamMC406_0485
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   BAMB398577:BAMMC406_0485-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 42809; Mature: 42809

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x9610180)-; HASH(0x13513818)-; HASH(0x1413cf04)-; HASH(0x12ad0020)-; HASH(0x1241b13c)-; HASH(0x128fb130)-; HASH(0x137424e8)-; HASH(0x1339ae44)-; HASH(0x960c554)-; HASH(0x96d5708)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKD
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPQSHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKV
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCHH
DLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGGSLGVFAY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHCCCHHHHHH
VMGSSVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGAL
HHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHCCHHHHHHHHHH
GTVAVIVRQEIVLFIMGGIFVAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEECC
GWKETQVVVRFWIITLMLCLFGLSTLKLR
CCCHHHHHHHHHHHHHHHHHHCHHHHCCH
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA