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The map label for this gene is hisC [H]

Identifier: 115350399

GI number: 115350399

Start: 388627

End: 389700

Strand: Direct

Name: hisC [H]

Synonym: Bamb_0344

Alternate gene names: 115350399

Gene position: 388627-389700 (Clockwise)

Preceding gene: 115350398

Following gene: 115350400

Centisome position: 10.93

GC content: 68.9

Gene sequence:

>1074_bases
ATGACGACGCCCCAAGACATCATCCGCCGCGACGTGCTCGCGATGACGAGCTACCCGGTGCCCGACGCGAGCGGCTTCGT
GAAGCTCGACGCGATGGAGAACCCGTATTCGCTGCCCGCGCCGCTGGCGGCCGCGCTCGGCGAGCGCCTCGCGCAGGTCG
CGCTGAACCGCTACCCGGCGCCGCGCCCGGGCGCGCTGCTCGACAAGCTGCGCCGCGCGATGGGCGTGCCGGCCGCGTGC
GACGTGCTGCTCGGCAACGGCTCGGACGAAATCATCAGCATGATGTCGGTGGCATGCGCGAAGCCGGGCGCGAAGGTGCT
CGCGCCGGTGCCGGGCTTTGTGATGTACGAGCTGTCCGCGAAGTTCGCGCAGCTCGAATTCGTCGGCGTGCCGCTCAAGG
CAGACCTGACGCTCGACGCCGACGCGATGATCGCGGCGATCGCCGAGCACCGGCCCGCGCTCGTCTATCTCGCGTACCCG
AACAATCCGACCGGCACGCTGTACGACGAAGCCGACGTCGAGCGGATCATCGCGGCCGCGCAACACAGCCTGATCGTGAT
CGACGAGGCGTATCAACCGTTCGCGGAGCGCTCGTGGCTGCCGCGCGCCGCCGAGTTCGACAACGTCGTCGTGATGCGCA
CGGTGTCGAAGCTCGGCCTGGCCGGCATCCGCCTCGGCTATCTCGCGGGGCTGCCCACCTGGCTGACCGAGTTCGACAAG
GTGCGCCCGCCGTACAACATCAACGTGCTGACCCAGGCGAGCGCCGATTTCCTGCTCGACCACCTCGACGTGCTCGATGC
GCAGGCGGCCGAACTGCGTGCGGAACGCACGCGCCTCGCGCAGGCCGTGGCCGCGCTGCCGGGCGCGACGGTGTTCCCGA
GCGCCGGCAATTTCCTGCTGGTGCGCGTGCCGGACGCGGCGGCGGTGTTCGATGCGCTGCTCACCGAGCGGGTGCTGATC
AAAAACGTGAGTAAAATGCATCCGTTGCTGGCCGAATGCGTGCGACTGACCGTCGGTTCTCCCGACGAAAACGCGCGCCT
GCTGGCTGCCTTGAAACTCGCGCTGCCCGGTTGA

Upstream 100 bases:

>100_bases
ACGCATCGGCCGCGGTCGACGAGGAGACCCTGCGCACGGCGGCAGCCGCCACCGTGCCGAGACCATTTGACGCCGGCGCG
AAGCACGCCGGCTTGAGACC

Downstream 100 bases:

>100_bases
GCCCAGGGCGCGGCGGCGCGCGACGATCAATCCCCATTTACATCAGACTCAATCAAGGAATTGCCATGCGTGTGGCGGAA
GTCGTTCGCAATACCAGCGA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTTPQDIIRRDVLAMTSYPVPDASGFVKLDAMENPYSLPAPLAAALGERLAQVALNRYPAPRPGALLDKLRRAMGVPAAC
DVLLGNGSDEIISMMSVACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLKADLTLDADAMIAAIAEHRPALVYLAYP
NNPTGTLYDEADVERIIAAAQHSLIVIDEAYQPFAERSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLAGLPTWLTEFDK
VRPPYNINVLTQASADFLLDHLDVLDAQAAELRAERTRLAQAVAALPGATVFPSAGNFLLVRVPDAAAVFDALLTERVLI
KNVSKMHPLLAECVRLTVGSPDENARLLAALKLALPG

Sequences:

>Translated_357_residues
MTTPQDIIRRDVLAMTSYPVPDASGFVKLDAMENPYSLPAPLAAALGERLAQVALNRYPAPRPGALLDKLRRAMGVPAAC
DVLLGNGSDEIISMMSVACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLKADLTLDADAMIAAIAEHRPALVYLAYP
NNPTGTLYDEADVERIIAAAQHSLIVIDEAYQPFAERSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLAGLPTWLTEFDK
VRPPYNINVLTQASADFLLDHLDVLDAQAAELRAERTRLAQAVAALPGATVFPSAGNFLLVRVPDAAAVFDALLTERVLI
KNVSKMHPLLAECVRLTVGSPDENARLLAALKLALPG
>Mature_356_residues
TTPQDIIRRDVLAMTSYPVPDASGFVKLDAMENPYSLPAPLAAALGERLAQVALNRYPAPRPGALLDKLRRAMGVPAACD
VLLGNGSDEIISMMSVACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLKADLTLDADAMIAAIAEHRPALVYLAYPN
NPTGTLYDEADVERIIAAAQHSLIVIDEAYQPFAERSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLAGLPTWLTEFDKV
RPPYNINVLTQASADFLLDHLDVLDAQAAELRAERTRLAQAVAALPGATVFPSAGNFLLVRVPDAAAVFDALLTERVLIK
NVSKMHPLLAECVRLTVGSPDENARLLAALKLALPG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=366, Percent_Identity=30.327868852459, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=365, Percent_Identity=27.9452054794521, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38285; Mature: 38154

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPQDIIRRDVLAMTSYPVPDASGFVKLDAMENPYSLPAPLAAALGERLAQVALNRYPA
CCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
PRPGALLDKLRRAMGVPAACDVLLGNGSDEIISMMSVACAKPGAKVLAPVPGFVMYELSA
CCCCHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEEHHHH
KFAQLEFVGVPLKADLTLDADAMIAAIAEHRPALVYLAYPNNPTGTLYDEADVERIIAAA
HHEEEEEEECCEEECCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHH
QHSLIVIDEAYQPFAERSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLAGLPTWLTEFDK
CCCEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VRPPYNINVLTQASADFLLDHLDVLDAQAAELRAERTRLAQAVAALPGATVFPSAGNFLL
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEE
VRVPDAAAVFDALLTERVLIKNVSKMHPLLAECVRLTVGSPDENARLLAALKLALPG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TTPQDIIRRDVLAMTSYPVPDASGFVKLDAMENPYSLPAPLAAALGERLAQVALNRYPA
CCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
PRPGALLDKLRRAMGVPAACDVLLGNGSDEIISMMSVACAKPGAKVLAPVPGFVMYELSA
CCCCHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEEHHHH
KFAQLEFVGVPLKADLTLDADAMIAAIAEHRPALVYLAYPNNPTGTLYDEADVERIIAAA
HHEEEEEEECCEEECCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHH
QHSLIVIDEAYQPFAERSWLPRAAEFDNVVVMRTVSKLGLAGIRLGYLAGLPTWLTEFDK
CCCEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VRPPYNINVLTQASADFLLDHLDVLDAQAAELRAERTRLAQAVAALPGATVFPSAGNFLL
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEE
VRVPDAAAVFDALLTERVLIKNVSKMHPLLAECVRLTVGSPDENARLLAALKLALPG
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12754231 [H]