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The map label for this gene is aprM

Identifier: 11499243

GI number: 11499243

Start: 1484788

End: 1485600

Strand: Reverse

Name: aprM

Synonym: AF1653

Alternate gene names: 11499243

Gene position: 1485600-1484788 (Counterclockwise)

Preceding gene: 11499244

Following gene: 11499242

Centisome position: 68.2

GC content: 49.32

Gene sequence:

>813_bases
ATGATGAGTATAAGGACAATAATAATAATGAGCTTGGTGATAATAGTGAGTCTCCAAACGGCAGCAGGAGTTCCAGTGAT
TATAAAGGTTGCGGACGGATATCTGGATGACGTTGCTGCCACAATGCACGGAGCAAAGAAAATAGAGCTGTTCAGCGTCA
TTGCGGCTGATTTGAGTGAAGATGAAATCAAAAAGCTGTCGGAGAATCCCTATGTTGAAGGAGTCTATCCCGACGTCGAC
GTAAAGGCCGTTGACGAAATACAGATGCTATCCATGCCTGATCTCTTCTCCACCACAGCAACGTCTGTCAGTGAAGCAGA
CGTGTGGAACCTTGACTTCATAAACGTCTCGGGAGTATGGAAAATGGGCTACAAGGGTAGCGGGGTTAAGGTTGCCGTCA
TAGACACCGGCGTTGCGAGGCACCCGGATTTTGCTGATAGAATCGTAGCCTTTGCTGACTTCGTCAACGGGCAAACTGAG
CCCTACGACGATAACGGACACGGAACTCACGTTGCAGGAACAATCGCTGGAGAGATAACAGGAGTCGCTCCGGAAGCGGA
AATCATGGCAGCAAAGGTTCTCGACAGCAGGGGGAGCGGGAAGCTCTCAACCGTTCTCATGGGGATACAGTGGGCCTATG
AAAATGGTGCGGACGTGATAAGCATGAGTCTTGGAGCATTGCCCGGATTGGGGGGAGCTACGGAAAAGTTCTCAACTCAG
GAGAGAGCTACGAAATTAATCTTCCGGTTTATTCGAGCCTCGGAGAAGTTTACGATGACATGGACAACTTCGTGCCGAGT
TACATTAAGCTGA

Upstream 100 bases:

>100_bases
TTAATATTTTTTAACTAATTCTTAAATTTGTTATTCTAATTTTTTCGGTATTTACTATTTTGTGAGAAAAATTTATTTAC
GGAAGGTTTGACCGATTTTC

Downstream 100 bases:

>100_bases
GGGTTAATCCCGACACGGTGAACTACGTCTGGGCTGCGCCGCCTTACGGTGGAACAAGGACCCTTGAAATGGACGTTGAC
AGGCCCTTCACGCTTAAGTT

Product: alkaline serine protease (aprM)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MMSIRTIIIMSLVIIVSLQTAAGVPVIIKVADGYLDDVAATMHGAKKIELFSVIAADLSEDEIKKLSENPYVEGVYPDVD
VKAVDEIQMLSMPDLFSTTATSVSEADVWNLDFINVSGVWKMGYKGSGVKVAVIDTGVARHPDFADRIVAFADFVNGQTE
PYDDNGHGTHVAGTIAGEITGVAPEAEIMAAKVLDSRGSGKLSTVLMGIQWAYENGADVISMSLGALPGLGGATEKFSTQ
ERATKLIFRFIRASEKFTMTWTTSCRVTLS

Sequences:

>Translated_270_residues
MMSIRTIIIMSLVIIVSLQTAAGVPVIIKVADGYLDDVAATMHGAKKIELFSVIAADLSEDEIKKLSENPYVEGVYPDVD
VKAVDEIQMLSMPDLFSTTATSVSEADVWNLDFINVSGVWKMGYKGSGVKVAVIDTGVARHPDFADRIVAFADFVNGQTE
PYDDNGHGTHVAGTIAGEITGVAPEAEIMAAKVLDSRGSGKLSTVLMGIQWAYENGADVISMSLGALPGLGGATEKFSTQ
ERATKLIFRFIRASEKFTMTWTTSCRVTLS
>Mature_270_residues
MMSIRTIIIMSLVIIVSLQTAAGVPVIIKVADGYLDDVAATMHGAKKIELFSVIAADLSEDEIKKLSENPYVEGVYPDVD
VKAVDEIQMLSMPDLFSTTATSVSEADVWNLDFINVSGVWKMGYKGSGVKVAVIDTGVARHPDFADRIVAFADFVNGQTE
PYDDNGHGTHVAGTIAGEITGVAPEAEIMAAKVLDSRGSGKLSTVLMGIQWAYENGADVISMSLGALPGLGGATEKFSTQ
ERATKLIFRFIRASEKFTMTWTTSCRVTLS

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=167, Percent_Identity=34.7305389221557, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319893, Length=102, Percent_Identity=37.2549019607843, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324576, Length=172, Percent_Identity=30.2325581395349, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 28920; Mature: 28920

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSIRTIIIMSLVIIVSLQTAAGVPVIIKVADGYLDDVAATMHGAKKIELFSVIAADLSE
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCCH
DEIKKLSENPYVEGVYPDVDVKAVDEIQMLSMPDLFSTTATSVSEADVWNLDFINVSGVW
HHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEEECCEE
KMGYKGSGVKVAVIDTGVARHPDFADRIVAFADFVNGQTEPYDDNGHGTHVAGTIAGEIT
EECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEE
GVAPEAEIMAAKVLDSRGSGKLSTVLMGIQWAYENGADVISMSLGALPGLGGATEKFSTQ
CCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCEEEEHHCCCCCCCCCCHHHHHH
ERATKLIFRFIRASEKFTMTWTTSCRVTLS
HHHHHHHHHHHHCCCEEEEEEEEEEEEEEC
>Mature Secondary Structure
MMSIRTIIIMSLVIIVSLQTAAGVPVIIKVADGYLDDVAATMHGAKKIELFSVIAADLSE
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCCH
DEIKKLSENPYVEGVYPDVDVKAVDEIQMLSMPDLFSTTATSVSEADVWNLDFINVSGVW
HHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEEECCEE
KMGYKGSGVKVAVIDTGVARHPDFADRIVAFADFVNGQTEPYDDNGHGTHVAGTIAGEIT
EECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEE
GVAPEAEIMAAKVLDSRGSGKLSTVLMGIQWAYENGADVISMSLGALPGLGGATEKFSTQ
CCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCEEEEHHCCCCCCCCCCHHHHHH
ERATKLIFRFIRASEKFTMTWTTSCRVTLS
HHHHHHHHHHHHCCCEEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2116590; 3142851; 7934828; 9384377 [H]