Click here to switch to the map view.

The map label for this gene is cat2-1

Identifier: 11498745

GI number: 11498745

Start: 1020246

End: 1021694

Strand: Reverse

Name: cat2-1

Synonym: AF1145

Alternate gene names: 11498745

Gene position: 1021694-1020246 (Counterclockwise)

Preceding gene: 11498746

Following gene: 11498744

Centisome position: 46.9

GC content: 53.28

Gene sequence:

>1449_bases
ATGAAGAGGTGTGATAGAATGAACTACAGGGAAGAATATGAAAAAAAGCTTATCAGTCCTGAAGAGGCTGCGGGGCTTGT
AGAGAGTGGAATGCACATCGAGCTTGGCGGTGCCGCAAATACAGCGCTCATAATAGACAAATACCTCGCAAAGAGAAAGG
ACGAGCTTGAAAACGTTAAAGTGGGTACTTTCATAGACCTCGCCCATTACGAGTTTCTCAAGGCCGACCCCAATGGGGAG
GTCTTCGAGTGGTCGAGCGGCTTCCTCTACCGACCCGTAAGAAAAACCAGCAAGGAGCTTGGACCGTGTGTATTCAGGCC
CAACCTGTATCACGACGTTCCGAAAATTGTCAGGGAGTTCTCCAAAGACTACGACCCGATAGACATCGCCTACCTCGTCA
CCACGCCCATGGACAAGCACGGCTACTTCAACTTCGGCCTGACCTGCTCGCACATGAAGGCGCTGGCAGAGGTTGCAGAG
AAGGTTGTGGTGGTCGTCAAAGAAAATATGCCCTGGGTCAATGGAGGCTACGACGAGTGCATCCACATCTCGGAAGTTGA
CTACATCGTTGAGGACAACGAGATGCCAGTTCCGTTCATACCATTCAGCATACCCCCAACGAAGGAGGATGAGATGATAG
CAGAGAACATACTCAACGCAGAAACGAAGGACGGCAGGAAGCTCATACAGGATGGCTCAACGCTTCAGGTTGGCATTGGC
GGTCTGCCGGATACGGTTGTTAAAATGCTCAAGGAAGGAGGGTACAAGAACCTCGGCGTGCACACCGAAATGATGGGCGA
TGGCACGCTTGAGTTGATTGAGGAGGGCGTTGTTACCAACGACCAGAAGAGGCTCGATAGGGGGAAGAGCGTTTTCACGT
TCGCCCTCGGCTCTCTCAAGCTCTACGAGTACCTCGACAGGAATCCGGAGGTTGCAACCTACCCAGTCGACTACACCAAC
GACCCCTTCATCATAGCGCAGCAGCCGAAGATGTTCTCCCTAAACCAGGCCGCAGAGGCCGACCTGATGGGCCAGATAAA
CTCGGAGCAGATGGGGCTGATATCACCAACAGGCAAGCTCTATCAGGTGAGCGGGACTGGGGGGCAGTTGGACTTCGTTA
TGGGCTGTCTTTTCAGCAGAGACAGACAGGGCTTCAGCATTCTCGCAATGTACTCCACACACAACGGTACGTCGAGGATC
AAGCCCATCCTGCCTCCTGGAGCGGCGGTGACTGTCCCGAGAAGCATGGTTCAGGTTGTTGCAACCGAGTGGGGAGTTGC
CTACCTGAAGGGGCTTACGGTAAAGGAAAGGGCAATAGCGATGATTCATCTCGCGCATCCAGACCACAGGGAGTGGCTGG
AGAAGGAGGCTGAAAAACTCGGTCTTCTACCGCCGAACTACACAATCCCGGCAGGCAAGCCGGATTACTTGCTCTACAAG
AGGGATTAA

Upstream 100 bases:

>100_bases
AATTTCATACGATAAAATTTTTAAGCTGCCCATTTTCCTAAAGGATTAATCAGAGTTATGTTTAATTCAGAAAACGTTAA
ATATTCTCCATAATTTTCAA

Downstream 100 bases:

>100_bases
GTTTTTAAATTTTTTCGCATAAGGCAAACTCATGCAACTGAAAAAGGCAGCTCTGCTGACATCAGGTGTTGCTTCCTTTC
TCACCCCCTTCATGGGCTCT

Product: 4-hydroxybutyrate CoA transferase (cat2-1)

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MKRCDRMNYREEYEKKLISPEEAAGLVESGMHIELGGAANTALIIDKYLAKRKDELENVKVGTFIDLAHYEFLKADPNGE
VFEWSSGFLYRPVRKTSKELGPCVFRPNLYHDVPKIVREFSKDYDPIDIAYLVTTPMDKHGYFNFGLTCSHMKALAEVAE
KVVVVVKENMPWVNGGYDECIHISEVDYIVEDNEMPVPFIPFSIPPTKEDEMIAENILNAETKDGRKLIQDGSTLQVGIG
GLPDTVVKMLKEGGYKNLGVHTEMMGDGTLELIEEGVVTNDQKRLDRGKSVFTFALGSLKLYEYLDRNPEVATYPVDYTN
DPFIIAQQPKMFSLNQAAEADLMGQINSEQMGLISPTGKLYQVSGTGGQLDFVMGCLFSRDRQGFSILAMYSTHNGTSRI
KPILPPGAAVTVPRSMVQVVATEWGVAYLKGLTVKERAIAMIHLAHPDHREWLEKEAEKLGLLPPNYTIPAGKPDYLLYK
RD

Sequences:

>Translated_482_residues
MKRCDRMNYREEYEKKLISPEEAAGLVESGMHIELGGAANTALIIDKYLAKRKDELENVKVGTFIDLAHYEFLKADPNGE
VFEWSSGFLYRPVRKTSKELGPCVFRPNLYHDVPKIVREFSKDYDPIDIAYLVTTPMDKHGYFNFGLTCSHMKALAEVAE
KVVVVVKENMPWVNGGYDECIHISEVDYIVEDNEMPVPFIPFSIPPTKEDEMIAENILNAETKDGRKLIQDGSTLQVGIG
GLPDTVVKMLKEGGYKNLGVHTEMMGDGTLELIEEGVVTNDQKRLDRGKSVFTFALGSLKLYEYLDRNPEVATYPVDYTN
DPFIIAQQPKMFSLNQAAEADLMGQINSEQMGLISPTGKLYQVSGTGGQLDFVMGCLFSRDRQGFSILAMYSTHNGTSRI
KPILPPGAAVTVPRSMVQVVATEWGVAYLKGLTVKERAIAMIHLAHPDHREWLEKEAEKLGLLPPNYTIPAGKPDYLLYK
RD
>Mature_482_residues
MKRCDRMNYREEYEKKLISPEEAAGLVESGMHIELGGAANTALIIDKYLAKRKDELENVKVGTFIDLAHYEFLKADPNGE
VFEWSSGFLYRPVRKTSKELGPCVFRPNLYHDVPKIVREFSKDYDPIDIAYLVTTPMDKHGYFNFGLTCSHMKALAEVAE
KVVVVVKENMPWVNGGYDECIHISEVDYIVEDNEMPVPFIPFSIPPTKEDEMIAENILNAETKDGRKLIQDGSTLQVGIG
GLPDTVVKMLKEGGYKNLGVHTEMMGDGTLELIEEGVVTNDQKRLDRGKSVFTFALGSLKLYEYLDRNPEVATYPVDYTN
DPFIIAQQPKMFSLNQAAEADLMGQINSEQMGLISPTGKLYQVSGTGGQLDFVMGCLFSRDRQGFSILAMYSTHNGTSRI
KPILPPGAAVTVPRSMVQVVATEWGVAYLKGLTVKERAIAMIHLAHPDHREWLEKEAEKLGLLPPNYTIPAGKPDYLLYK
RD

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=229, Percent_Identity=25.3275109170306, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI32563853, Length=491, Percent_Identity=31.1608961303462, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17538151, Length=458, Percent_Identity=30.7860262008734, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21358615, Length=460, Percent_Identity=35, Blast_Score=238, Evalue=8e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 54019; Mature: 54019

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRCDRMNYREEYEKKLISPEEAAGLVESGMHIELGGAANTALIIDKYLAKRKDELENVK
CCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCE
VGTFIDLAHYEFLKADPNGEVFEWSSGFLYRPVRKTSKELGPCVFRPNLYHDVPKIVREF
ECEEEEEHHHHEEEECCCCCEEEECCCCEECCHHHHHHHCCCEEECCCHHHHHHHHHHHH
SKDYDPIDIAYLVTTPMDKHGYFNFGLTCSHMKALAEVAEKVVVVVKENMPWVNGGYDEC
HCCCCCEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHE
IHISEVDYIVEDNEMPVPFIPFSIPPTKEDEMIAENILNAETKDGRKLIQDGSTLQVGIG
EEEECEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCEEEEECC
GLPDTVVKMLKEGGYKNLGVHTEMMGDGTLELIEEGVVTNDQKRLDRGKSVFTFALGSLK
CCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCCCCCHHHHHCCCEEEEEHHHHHH
LYEYLDRNPEVATYPVDYTNDPFIIAQQPKMFSLNQAAEADLMGQINSEQMGLISPTGKL
HHHHHCCCCCEEEEECCCCCCCEEEECCCCCEECCHHHHHHHHCCCCCCCCEEECCCCCE
YQVSGTGGQLDFVMGCLFSRDRQGFSILAMYSTHNGTSRIKPILPPGAAVTVPRSMVQVV
EEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHH
ATEWGVAYLKGLTVKERAIAMIHLAHPDHREWLEKEAEKLGLLPPNYTIPAGKPDYLLYK
HHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
RD
CC
>Mature Secondary Structure
MKRCDRMNYREEYEKKLISPEEAAGLVESGMHIELGGAANTALIIDKYLAKRKDELENVK
CCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCE
VGTFIDLAHYEFLKADPNGEVFEWSSGFLYRPVRKTSKELGPCVFRPNLYHDVPKIVREF
ECEEEEEHHHHEEEECCCCCEEEECCCCEECCHHHHHHHCCCEEECCCHHHHHHHHHHHH
SKDYDPIDIAYLVTTPMDKHGYFNFGLTCSHMKALAEVAEKVVVVVKENMPWVNGGYDEC
HCCCCCEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHE
IHISEVDYIVEDNEMPVPFIPFSIPPTKEDEMIAENILNAETKDGRKLIQDGSTLQVGIG
EEEECEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCEEEEECC
GLPDTVVKMLKEGGYKNLGVHTEMMGDGTLELIEEGVVTNDQKRLDRGKSVFTFALGSLK
CCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCCCCCHHHHHCCCEEEEEHHHHHH
LYEYLDRNPEVATYPVDYTNDPFIIAQQPKMFSLNQAAEADLMGQINSEQMGLISPTGKL
HHHHHCCCCCEEEEECCCCCCCEEEECCCCCEECCHHHHHHHHCCCCCCCCEEECCCCCE
YQVSGTGGQLDFVMGCLFSRDRQGFSILAMYSTHNGTSRIKPILPPGAAVTVPRSMVQVV
EEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHH
ATEWGVAYLKGLTVKERAIAMIHLAHPDHREWLEKEAEKLGLLPPNYTIPAGKPDYLLYK
HHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
RD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]