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The map label for this gene is proW-1

Identifier: 11498584

GI number: 11498584

Start: 881411

End: 882025

Strand: Reverse

Name: proW-1

Synonym: AF0979

Alternate gene names: 11498584

Gene position: 882025-881411 (Counterclockwise)

Preceding gene: 11498585

Following gene: 11498575

Centisome position: 40.49

GC content: 52.52

Gene sequence:

>615_bases
ATGATTGAGCTGCTGAAGGTTCTCGCTGCCACCTACGAGCACCTCCTTCTAACCTATGGGGCGCTGGCCGTAAGCATAGC
CCTTGCCATCCCCCTCGCCATCGCCTCGGTTTACAGCAGGAAGCTTGCATCGGTTATTATGGCCTTCGCCAACGTCGTTC
AGGCAGTTCCGAGCTTTGCCGTTGTTGCGCTTGTCGTCCCCTTCCTCGGAATAGGCTTCACTCCAGCCGTTTTCGCCATC
GTTCTGAGAGCTCTTTTACCGATAGTCAGAAACACCTACGTTGGGATGATGAGCGTTGATGAGGCTACCATTGATGCTGC
GAGGGGCATAGGCCTCACTGACTTCCAAATCATCCGCTACATCCGCCTCCCCAACGCCTACGCCCCGATGTTTGCGGGGA
TAAAGTTTGCAGGGATTCTTGCCAACAGCATAGCCATTCTAACTGCTATTATTGGTAGTGGGGGGCTCGGAAGGCTTGTG
TTTGAGGGCTTGGCGAGCTTCAACACCGAGAAGGTTATAGCCGGAGCGCTGCCTGCAATCCTTATAGCCGTCTTTATCGA
CGTAAGCTTTACAAAAATAGAAGGAAGATTCGGCTCAGATAATTCTTCTCGTTAA

Upstream 100 bases:

>100_bases
ATACTCGTTGCGGGTTTATGGGTTGGGATTCTTGCTGTATTGCTCGACGCCTTTGCCGGGGCTGTTGAGAGAGTTTTGAG
CAGAAAATTCAGGGGAGAGT

Downstream 100 bases:

>100_bases
ACTTCCTCCTCACCCGTCCTTATCTTGACTGACTTCTCCACTGGAATAACGAATATCCTCCCATCACCGAACTTCCCAGT
TCTTGCCGAACTCACTATCG

Product: osmoprotection protein (proW-1)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIELLKVLAATYEHLLLTYGALAVSIALAIPLAIASVYSRKLASVIMAFANVVQAVPSFAVVALVVPFLGIGFTPAVFAI
VLRALLPIVRNTYVGMMSVDEATIDAARGIGLTDFQIIRYIRLPNAYAPMFAGIKFAGILANSIAILTAIIGSGGLGRLV
FEGLASFNTEKVIAGALPAILIAVFIDVSFTKIEGRFGSDNSSR

Sequences:

>Translated_204_residues
MIELLKVLAATYEHLLLTYGALAVSIALAIPLAIASVYSRKLASVIMAFANVVQAVPSFAVVALVVPFLGIGFTPAVFAI
VLRALLPIVRNTYVGMMSVDEATIDAARGIGLTDFQIIRYIRLPNAYAPMFAGIKFAGILANSIAILTAIIGSGGLGRLV
FEGLASFNTEKVIAGALPAILIAVFIDVSFTKIEGRFGSDNSSR
>Mature_204_residues
MIELLKVLAATYEHLLLTYGALAVSIALAIPLAIASVYSRKLASVIMAFANVVQAVPSFAVVALVVPFLGIGFTPAVFAI
VLRALLPIVRNTYVGMMSVDEATIDAARGIGLTDFQIIRYIRLPNAYAPMFAGIKFAGILANSIAILTAIIGSGGLGRLV
FEGLASFNTEKVIAGALPAILIAVFIDVSFTKIEGRFGSDNSSR

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=194, Percent_Identity=32.9896907216495, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788449, Length=162, Percent_Identity=30.8641975308642, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789033, Length=180, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI87081802, Length=145, Percent_Identity=26.2068965517241, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 21462; Mature: 21462

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELLKVLAATYEHLLLTYGALAVSIALAIPLAIASVYSRKLASVIMAFANVVQAVPSFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVALVVPFLGIGFTPAVFAIVLRALLPIVRNTYVGMMSVDEATIDAARGIGLTDFQIIRY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHH
IRLPNAYAPMFAGIKFAGILANSIAILTAIIGSGGLGRLVFEGLASFNTEKVIAGALPAI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
LIAVFIDVSFTKIEGRFGSDNSSR
HHHHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure
MIELLKVLAATYEHLLLTYGALAVSIALAIPLAIASVYSRKLASVIMAFANVVQAVPSFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVALVVPFLGIGFTPAVFAIVLRALLPIVRNTYVGMMSVDEATIDAARGIGLTDFQIIRY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHH
IRLPNAYAPMFAGIKFAGILANSIAILTAIIGSGGLGRLVFEGLASFNTEKVIAGALPAI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
LIAVFIDVSFTKIEGRFGSDNSSR
HHHHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]