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The map label for this gene is lldD

Identifier: 11498413

GI number: 11498413

Start: 717638

End: 718738

Strand: Reverse

Name: lldD

Synonym: AF0807

Alternate gene names: 11498413

Gene position: 718738-717638 (Counterclockwise)

Preceding gene: 11498419

Following gene: 11498411

Centisome position: 32.99

GC content: 47.14

Gene sequence:

>1101_bases
GTGGAGCGTTACAACAAGAGGGTCGGTGCTGACGTTCCCCTTACCAAGGATTTTCTCAAGCTCTTTTGTTATCTTCATTA
CATTACAAAGATCATTGAAACAATTTGGTTTTGGGGTTCATATGTTTACCATATCTTTTATATTTTTTTAGAGCGTGCTG
GTAACATGAAAACGATAGACGAGCTTGTTGAAAGCGCCAGACAGATACTTCAGGAAAGGGATGTGAACATAGAGGTTTTA
GAGGGGGGTACGGAGAGGGGGTTGACGGTAAGGAGAAACAGAGAGATTTTAGACTCCATCGGAATAAAAATGAACCTCCT
ATCAGACTTCGAACCTTCTTTGGAAACGGAATTTCTCGGAAGGAAGATTTCCATGCCTGTTATGCCGGCCCCGCTTTCAG
GGCTGGTAAAATCTGTGGATGCCAACTGTTTTAAGAGAATAATCCGCGAAGCGTGGGAGGCGGGGGTTGTTCCGTGGATA
GGCCATCCTATTCAGGATGATGTTTCGGAATTCGAGAAGGAGTTCGTCTGGATTATCAAGCCTCTCAGAAACACCAAGAG
AGTGTACGATGATGTTGAGAAGGCAGAATCGTCAAAGGCCATGGCAATTGGCATGGACATTGACTCTGCAGCGGGAATAA
AGGTTGGGGGGACAATTCTGAGCTACGGGGGAACTAAGGTGTGGAGCAAGAAGGAGCTTGCTGACCTCGCCTCCACGACG
AAGTTGCCATTCATCGTCAAGGGGGTTCTCAGTGAGAGGGATTACTACTCACTCGCCGACATTAGCTCTGCCATTGTCGT
CTCGAATCACGGCGGGAGGGTGCTCGATTCGGCTATTTCTCCGCTCGAACTTCTGCCATACTTAGAGAAAGTGGTTCCAA
CCGGTGTTGACAGCGGCTTCAGGTACGGCTCGGATGTGTTCAAGGCCTTAGCTCTGGGAGCCGATTTCGTCCTTTTTGGC
AGACTCATGGTTTACGCGCTTGCAATTGAAAACGGAGTTCAGACTGCTTTAAACATGATCAGGGATGAGCTTTTGAGGAT
TATGAAGCTCACGGGAGCGAAAAGTGTGAAAGAAATAAGTAAAGAAGCTGTTGTGCTTTAA

Upstream 100 bases:

>100_bases
TGTTCTCGTAGCAGAGTTTTGCAATCCTCGCAACCTGCTCCGTATTTTCCGGAAAAACTACCGCAGTTGCGTTACCGGCT
TTTCCAATAGCATCAGTCGA

Downstream 100 bases:

>100_bases
TTTTTTTAAATCATTTGTATTTTCAGGATGAAGACTGCTATCGCCGCCACCACGCTGACAACTATTGCGTAAATCGTTGC
CGGCACGAGGTTCTTCCTGA

Product: L-lactate dehydrogenase, cytochrome-type (lldD)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MERYNKRVGADVPLTKDFLKLFCYLHYITKIIETIWFWGSYVYHIFYIFLERAGNMKTIDELVESARQILQERDVNIEVL
EGGTERGLTVRRNREILDSIGIKMNLLSDFEPSLETEFLGRKISMPVMPAPLSGLVKSVDANCFKRIIREAWEAGVVPWI
GHPIQDDVSEFEKEFVWIIKPLRNTKRVYDDVEKAESSKAMAIGMDIDSAAGIKVGGTILSYGGTKVWSKKELADLASTT
KLPFIVKGVLSERDYYSLADISSAIVVSNHGGRVLDSAISPLELLPYLEKVVPTGVDSGFRYGSDVFKALALGADFVLFG
RLMVYALAIENGVQTALNMIRDELLRIMKLTGAKSVKEISKEAVVL

Sequences:

>Translated_366_residues
MERYNKRVGADVPLTKDFLKLFCYLHYITKIIETIWFWGSYVYHIFYIFLERAGNMKTIDELVESARQILQERDVNIEVL
EGGTERGLTVRRNREILDSIGIKMNLLSDFEPSLETEFLGRKISMPVMPAPLSGLVKSVDANCFKRIIREAWEAGVVPWI
GHPIQDDVSEFEKEFVWIIKPLRNTKRVYDDVEKAESSKAMAIGMDIDSAAGIKVGGTILSYGGTKVWSKKELADLASTT
KLPFIVKGVLSERDYYSLADISSAIVVSNHGGRVLDSAISPLELLPYLEKVVPTGVDSGFRYGSDVFKALALGADFVLFG
RLMVYALAIENGVQTALNMIRDELLRIMKLTGAKSVKEISKEAVVL
>Mature_366_residues
MERYNKRVGADVPLTKDFLKLFCYLHYITKIIETIWFWGSYVYHIFYIFLERAGNMKTIDELVESARQILQERDVNIEVL
EGGTERGLTVRRNREILDSIGIKMNLLSDFEPSLETEFLGRKISMPVMPAPLSGLVKSVDANCFKRIIREAWEAGVVPWI
GHPIQDDVSEFEKEFVWIIKPLRNTKRVYDDVEKAESSKAMAIGMDIDSAAGIKVGGTILSYGGTKVWSKKELADLASTT
KLPFIVKGVLSERDYYSLADISSAIVVSNHGGRVLDSAISPLELLPYLEKVVPTGVDSGFRYGSDVFKALALGADFVLFG
RLMVYALAIENGVQTALNMIRDELLRIMKLTGAKSVKEISKEAVVL

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=326, Percent_Identity=28.5276073619632, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7705393, Length=326, Percent_Identity=28.5276073619632, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI11068137, Length=136, Percent_Identity=39.7058823529412, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1790033, Length=130, Percent_Identity=43.0769230769231, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193208036, Length=137, Percent_Identity=37.956204379562, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323587, Length=162, Percent_Identity=38.2716049382716, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI78707188, Length=142, Percent_Identity=37.3239436619718, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281363140, Length=148, Percent_Identity=37.1621621621622, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI78707190, Length=148, Percent_Identity=37.1621621621622, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 41016; Mature: 41016

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERYNKRVGADVPLTKDFLKLFCYLHYITKIIETIWFWGSYVYHIFYIFLERAGNMKTID
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ELVESARQILQERDVNIEVLEGGTERGLTVRRNREILDSIGIKMNLLSDFEPSLETEFLG
HHHHHHHHHHHHCCCCEEEECCCCCCCCEECCCHHHHHHCCCEEEHHHCCCCCHHHHHHC
RKISMPVMPAPLSGLVKSVDANCFKRIIREAWEAGVVPWIGHPIQDDVSEFEKEFVWIIK
CCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
PLRNTKRVYDDVEKAESSKAMAIGMDIDSAAGIKVGGTILSYGGTKVWSKKELADLASTT
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECCEEEECCCCCCCCHHHHHHHHHHC
KLPFIVKGVLSERDYYSLADISSAIVVSNHGGRVLDSAISPLELLPYLEKVVPTGVDSGF
CCHHHHHHHHCCCCCHHHHHHCCEEEEECCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCC
RYGSDVFKALALGADFVLFGRLMVYALAIENGVQTALNMIRDELLRIMKLTGAKSVKEIS
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KEAVVL
HHHCCC
>Mature Secondary Structure
MERYNKRVGADVPLTKDFLKLFCYLHYITKIIETIWFWGSYVYHIFYIFLERAGNMKTID
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ELVESARQILQERDVNIEVLEGGTERGLTVRRNREILDSIGIKMNLLSDFEPSLETEFLG
HHHHHHHHHHHHCCCCEEEECCCCCCCCEECCCHHHHHHCCCEEEHHHCCCCCHHHHHHC
RKISMPVMPAPLSGLVKSVDANCFKRIIREAWEAGVVPWIGHPIQDDVSEFEKEFVWIIK
CCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
PLRNTKRVYDDVEKAESSKAMAIGMDIDSAAGIKVGGTILSYGGTKVWSKKELADLASTT
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEECCEEEECCCCCCCCHHHHHHHHHHC
KLPFIVKGVLSERDYYSLADISSAIVVSNHGGRVLDSAISPLELLPYLEKVVPTGVDSGF
CCHHHHHHHHCCCCCHHHHHHCCEEEEECCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCC
RYGSDVFKALALGADFVLFGRLMVYALAIENGVQTALNMIRDELLRIMKLTGAKSVKEIS
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KEAVVL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA