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The map label for this gene is ileS

Identifier: 11498241

GI number: 11498241

Start: 568005

End: 571061

Strand: Reverse

Name: ileS

Synonym: AF0633

Alternate gene names: 11498241

Gene position: 571061-568005 (Counterclockwise)

Preceding gene: 11498243

Following gene: 11498240

Centisome position: 26.21

GC content: 51.29

Gene sequence:

>3057_bases
ATGCTTCCCGCTAAATACTCACCGAAGGATGTGGAATCTGAAATTTTCAAGTTCTGGGAGGATAATGACATCTACAGAAA
AGTTAAGGAGAAAGGTGGAAGAAAGTTTTACTTCGTTGATGGCCCACCCTACACAACAGGAAGGATTCATCTGGGAACTG
CGTGGAATAAAGTTCTGAAGGATACCATTCTGCGCTACAAGAGGATGATGGGCTTTGCTCCCACAGACACTCCGGGCTGG
GACATGCATGGTTTGCCAATTGAAGTTAAGGTGGAGCAGGAGCTTGGATTCAGAACAAAGAGGGACATTGAGAGTTTTGG
AATTGATAAGTTCATCGAGAGGTGCATGAACTACGCTCTGGCCAACAAAGACGCCATGACGGAGCAGTTCAAGAGCCTCG
CAGTCTGGATGGACTGGGAGAATCCCTACATGACCATCAAGGCTGAGTACATGAACGCTGCGTGGTTTGCGATCAAGAGG
GCTCACGAGAGGGGGCTGCTTGAGAGGAAGAAGATGGTTGTTAACTGGTGCCACCGCTGTGAAACGGCACTGGCTGATGC
TGAGGTGGAGTACTGGGATGAGGAGGACCCCTCAATCTACGTCAAGTTCCCCGTAAAGGGGGAGAAGGACACCTACATCG
TCATCTGGACCACCACGCCCTGGACACTTCCAGCCAACATGGCCGTTGCCGTTCATCCATCACTTGAGTACGCAAAGTTC
AGGGCGGTTAAGGACGGGAAGGTTGAATATTTAATCCTCGCAAAGGAGCTTGCCGACTCCGTATTGGGAAAGGGAGACTA
CGACAGCTGGGAGGTGGTTGAAACCTACCTCGGAGAGGATTTAGAGGGTCTGGAGTACGAGCACCCCCTTGCCGATGAAG
TGCCGTTGCAGAAGAACTGGAAGCATCAGGTTTTCTTTGCTGACTTCGTCACTGCTGAAAACACGGGCTGTGTCCACATT
GCTCCGGGGCACGGTGTTGAGGACTATGAGCTTGGAGTGGAGAAGGGACTGGAGGTTTTCAATCCCGTTGACGACAGGGG
GGTTTACACTGAGGAGGCAGGCAAATACGCAGGAAAGCACGTGAAGGAGGCCAATGACGACATCATTGACGACCTCTACC
GCAAGGATTTGCTGCTGGCTGAGGAGAGAATTGTTCACCGCTACGGCCACTGCTGGCGCTGCAAGACGCCAATCATTTAC
AGAGCAACGGAGCAGTGGTTCATCAAGATTTCAGAGCTGAAGGATGAGATGCTGGAGGAAATAGACAAGGTAATGTGGAT
TCCCGAGTGGGCGGGAAGTGCGAGGTTCAAGGACTGGGTCAGCAACGCCAAGGACTGGTGCATAAGCAGGCAACGCTACT
GGGGCATCCCCATTCCTGTCTGGATTTGCGAAAAGTGCGGAGAGATGAAGGTTGTCGGCAGCATTAACGAGATAGAGTGG
GAAAACGACCTCGATTTGCACAGACCCAAAATTGACGCCGTAACGTTCAGCTGTCAGTGCGGAGGGGTAATGAGGAGAGT
TCCAGATGTCTTTGATGTCTGGTTCGACAGTGGTGTGGCGAGCTGGGGGAGTATTGCTTATCCACTCAGAAAGGACAAAT
TCGAGGAGCTTTGGCCCGCAGATTTTATCACAGAAGGGCACGACCAGACGAGGGGATGGTTCTACTCCCAGCTTGGCACT
TCAGTTGTTTGCTTTGATAAAGCCCCCTACAAAGCTGTTTTGATGCACGGCTTCACACTTGACGAGCAGGGAAGGAAGAT
GAGCAAGAGCCTCGGCAACGTTGTTGAGCCCGAGGAGGTTGTTGGCCAGATTGGCGTTGACGGCTTCAGGCTCTACGTCC
TCTACTCCGCTCCCTGGGAGGACCTGAGGTTCAGCTGGGAGGAGGCGAGGAACATAAACAGAATGCTCAACGTCGTGTGG
AATGCTGTCAGATTTGCCCACACCTACATGAGCCTTGATAATTACAGCTTTGGCGAGAAGGGAGAGCTTAAGATTGAGGA
CAGGTGGATTCTATCAAGGCTTGAGAGCTTTATAAAGGAGGCTAACGAGGCCATGGAAGGCTATCAGGTCCACAGAGTTG
TCAGAGCCTTCTTTGACTTCTTCGTTGAGGACTTCAGCAGGTGGTACATCCAGATTATCAGGCCGAGAGTGTGGGAGGAG
AGGGATTCCCCATCGAAGCTCGCAGCCTACTACACGATGTTCAGGGTGATTGACAGGTCTTTGAGAGCTATAGCCCCCTT
CGCCCCGCTCATTGCGGAGTGGTTCTACCAGCACGTTGTAAAGGAGTTCAGGGAGGGGGAGGAGTCCATTTTCATGGAGG
AGTATTCCACTGCTGAGGTTGAGATGATTGATGGCGAGCTTGAGGCAGCAATGAAGGTTGCGAAGGAGATTGTAGAGGCT
GCAGCCAATGCAAGGAACAAGGCAAAGAGGAAGCTGAGGTGGCCTTTGAGGGAGCTTGTTATAGAGTCGGGCAGCGAGAA
GGTAAGAAAGGCTGTGGAGATGCTTGAGGAGACAATTTTGAGCCAGTGCAACGTTAAGCAGGTTAGAGTGGTTGACAGCT
TTGAGAAGGAGATTGAAATCAAGCCGAACTACAAGTACATCGGCCCGTTGCTCAAAGAAAAGGCTGGGGAATTTGCGAAG
TACGTGGCATCGCTTAAGGAGATTCCCGAAAAGCTCGTTTTCGATGGTGTGGAGCTTGACCCCAAGCAGGCCATAGTTGT
GGACTACAGGCTGCCTGAAGGATACGAGTATGCAGAGTTTTCAGGAGGAGTGGTTTACATCTACAAGGAGCTCGACGATG
AGCTTGTGAGGGAGGCATTTGCCAGAGAGGTTATTAGGAGAATTCAGGAGATGAGAAAGGAGCTCGACCTCGACGTCGAG
GAGTTCATTGAAACGACAGTGGAGATGGATGCCGAGCTCGTCAAAGGCTGGGAAGACTACATAAAGAGCGAGACGAGGTC
ACAGAAGCTGGTTTTCGGCAAAGCAGAGGGGTACGTTAGAGAGTGGAATATTGAGGGAAAGAAGGTTAAAATAGGAATAA
AAAGGCTGAGGGGTTAG

Upstream 100 bases:

>100_bases
TAATTTTTGCTGCCCCACCATGATGGTATATGCTTTTGCATGTCAAAATTCCGGAAAGGAAAGCTGATAACTTTTTTAAT
CCACCGGCTGTTCAGGTTTC

Downstream 100 bases:

>100_bases
AAATCCCTCCAATTTTTGTTTGTGTACTCCTCCTCTTTCAAACCAAAAAGCTTATTATTTCCGTCAAGGGAAGAGATTTT
ATGTCGTTAAGAGAGAAAGT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1018; Mature: 1018

Protein sequence:

>1018_residues
MLPAKYSPKDVESEIFKFWEDNDIYRKVKEKGGRKFYFVDGPPYTTGRIHLGTAWNKVLKDTILRYKRMMGFAPTDTPGW
DMHGLPIEVKVEQELGFRTKRDIESFGIDKFIERCMNYALANKDAMTEQFKSLAVWMDWENPYMTIKAEYMNAAWFAIKR
AHERGLLERKKMVVNWCHRCETALADAEVEYWDEEDPSIYVKFPVKGEKDTYIVIWTTTPWTLPANMAVAVHPSLEYAKF
RAVKDGKVEYLILAKELADSVLGKGDYDSWEVVETYLGEDLEGLEYEHPLADEVPLQKNWKHQVFFADFVTAENTGCVHI
APGHGVEDYELGVEKGLEVFNPVDDRGVYTEEAGKYAGKHVKEANDDIIDDLYRKDLLLAEERIVHRYGHCWRCKTPIIY
RATEQWFIKISELKDEMLEEIDKVMWIPEWAGSARFKDWVSNAKDWCISRQRYWGIPIPVWICEKCGEMKVVGSINEIEW
ENDLDLHRPKIDAVTFSCQCGGVMRRVPDVFDVWFDSGVASWGSIAYPLRKDKFEELWPADFITEGHDQTRGWFYSQLGT
SVVCFDKAPYKAVLMHGFTLDEQGRKMSKSLGNVVEPEEVVGQIGVDGFRLYVLYSAPWEDLRFSWEEARNINRMLNVVW
NAVRFAHTYMSLDNYSFGEKGELKIEDRWILSRLESFIKEANEAMEGYQVHRVVRAFFDFFVEDFSRWYIQIIRPRVWEE
RDSPSKLAAYYTMFRVIDRSLRAIAPFAPLIAEWFYQHVVKEFREGEESIFMEEYSTAEVEMIDGELEAAMKVAKEIVEA
AANARNKAKRKLRWPLRELVIESGSEKVRKAVEMLEETILSQCNVKQVRVVDSFEKEIEIKPNYKYIGPLLKEKAGEFAK
YVASLKEIPEKLVFDGVELDPKQAIVVDYRLPEGYEYAEFSGGVVYIYKELDDELVREAFAREVIRRIQEMRKELDLDVE
EFIETTVEMDAELVKGWEDYIKSETRSQKLVFGKAEGYVREWNIEGKKVKIGIKRLRG

Sequences:

>Translated_1018_residues
MLPAKYSPKDVESEIFKFWEDNDIYRKVKEKGGRKFYFVDGPPYTTGRIHLGTAWNKVLKDTILRYKRMMGFAPTDTPGW
DMHGLPIEVKVEQELGFRTKRDIESFGIDKFIERCMNYALANKDAMTEQFKSLAVWMDWENPYMTIKAEYMNAAWFAIKR
AHERGLLERKKMVVNWCHRCETALADAEVEYWDEEDPSIYVKFPVKGEKDTYIVIWTTTPWTLPANMAVAVHPSLEYAKF
RAVKDGKVEYLILAKELADSVLGKGDYDSWEVVETYLGEDLEGLEYEHPLADEVPLQKNWKHQVFFADFVTAENTGCVHI
APGHGVEDYELGVEKGLEVFNPVDDRGVYTEEAGKYAGKHVKEANDDIIDDLYRKDLLLAEERIVHRYGHCWRCKTPIIY
RATEQWFIKISELKDEMLEEIDKVMWIPEWAGSARFKDWVSNAKDWCISRQRYWGIPIPVWICEKCGEMKVVGSINEIEW
ENDLDLHRPKIDAVTFSCQCGGVMRRVPDVFDVWFDSGVASWGSIAYPLRKDKFEELWPADFITEGHDQTRGWFYSQLGT
SVVCFDKAPYKAVLMHGFTLDEQGRKMSKSLGNVVEPEEVVGQIGVDGFRLYVLYSAPWEDLRFSWEEARNINRMLNVVW
NAVRFAHTYMSLDNYSFGEKGELKIEDRWILSRLESFIKEANEAMEGYQVHRVVRAFFDFFVEDFSRWYIQIIRPRVWEE
RDSPSKLAAYYTMFRVIDRSLRAIAPFAPLIAEWFYQHVVKEFREGEESIFMEEYSTAEVEMIDGELEAAMKVAKEIVEA
AANARNKAKRKLRWPLRELVIESGSEKVRKAVEMLEETILSQCNVKQVRVVDSFEKEIEIKPNYKYIGPLLKEKAGEFAK
YVASLKEIPEKLVFDGVELDPKQAIVVDYRLPEGYEYAEFSGGVVYIYKELDDELVREAFAREVIRRIQEMRKELDLDVE
EFIETTVEMDAELVKGWEDYIKSETRSQKLVFGKAEGYVREWNIEGKKVKIGIKRLRG
>Mature_1018_residues
MLPAKYSPKDVESEIFKFWEDNDIYRKVKEKGGRKFYFVDGPPYTTGRIHLGTAWNKVLKDTILRYKRMMGFAPTDTPGW
DMHGLPIEVKVEQELGFRTKRDIESFGIDKFIERCMNYALANKDAMTEQFKSLAVWMDWENPYMTIKAEYMNAAWFAIKR
AHERGLLERKKMVVNWCHRCETALADAEVEYWDEEDPSIYVKFPVKGEKDTYIVIWTTTPWTLPANMAVAVHPSLEYAKF
RAVKDGKVEYLILAKELADSVLGKGDYDSWEVVETYLGEDLEGLEYEHPLADEVPLQKNWKHQVFFADFVTAENTGCVHI
APGHGVEDYELGVEKGLEVFNPVDDRGVYTEEAGKYAGKHVKEANDDIIDDLYRKDLLLAEERIVHRYGHCWRCKTPIIY
RATEQWFIKISELKDEMLEEIDKVMWIPEWAGSARFKDWVSNAKDWCISRQRYWGIPIPVWICEKCGEMKVVGSINEIEW
ENDLDLHRPKIDAVTFSCQCGGVMRRVPDVFDVWFDSGVASWGSIAYPLRKDKFEELWPADFITEGHDQTRGWFYSQLGT
SVVCFDKAPYKAVLMHGFTLDEQGRKMSKSLGNVVEPEEVVGQIGVDGFRLYVLYSAPWEDLRFSWEEARNINRMLNVVW
NAVRFAHTYMSLDNYSFGEKGELKIEDRWILSRLESFIKEANEAMEGYQVHRVVRAFFDFFVEDFSRWYIQIIRPRVWEE
RDSPSKLAAYYTMFRVIDRSLRAIAPFAPLIAEWFYQHVVKEFREGEESIFMEEYSTAEVEMIDGELEAAMKVAKEIVEA
AANARNKAKRKLRWPLRELVIESGSEKVRKAVEMLEETILSQCNVKQVRVVDSFEKEIEIKPNYKYIGPLLKEKAGEFAK
YVASLKEIPEKLVFDGVELDPKQAIVVDYRLPEGYEYAEFSGGVVYIYKELDDELVREAFAREVIRRIQEMRKELDLDVE
EFIETTVEMDAELVKGWEDYIKSETRSQKLVFGKAEGYVREWNIEGKKVKIGIKRLRG

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1005, Percent_Identity=32.1393034825871, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI94721241, Length=1005, Percent_Identity=32.1393034825871, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI46852147, Length=811, Percent_Identity=33.6621454993835, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI268370293, Length=831, Percent_Identity=24.5487364620939, Blast_Score=245, Evalue=2e-64,
Organism=Homo sapiens, GI268370297, Length=829, Percent_Identity=24.6079613992762, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI5454158, Length=847, Percent_Identity=24.4391971664699, Blast_Score=241, Evalue=3e-63,
Organism=Homo sapiens, GI268370295, Length=784, Percent_Identity=24.7448979591837, Blast_Score=230, Evalue=4e-60,
Organism=Escherichia coli, GI2367096, Length=778, Percent_Identity=35.8611825192802, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1790708, Length=1001, Percent_Identity=23.1768231768232, Blast_Score=235, Evalue=1e-62,
Organism=Escherichia coli, GI1786861, Length=767, Percent_Identity=22.5554106910039, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17541896, Length=990, Percent_Identity=31.3131313131313, Blast_Score=494, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI71980946, Length=798, Percent_Identity=29.9498746867168, Blast_Score=318, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI17510661, Length=884, Percent_Identity=25.7918552036199, Blast_Score=260, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI72001587, Length=895, Percent_Identity=23.1284916201117, Blast_Score=197, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1044, Percent_Identity=31.8007662835249, Blast_Score=508, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6325217, Length=799, Percent_Identity=30.7884856070088, Blast_Score=347, Evalue=6e-96,
Organism=Saccharomyces cerevisiae, GI6321531, Length=871, Percent_Identity=24.1102181400689, Blast_Score=232, Evalue=2e-61,
Organism=Drosophila melanogaster, GI28574730, Length=1007, Percent_Identity=30.0893743793446, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24668547, Length=1007, Percent_Identity=30.0893743793446, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24668543, Length=1007, Percent_Identity=30.0893743793446, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI281366294, Length=780, Percent_Identity=31.5384615384615, Blast_Score=348, Evalue=1e-95,
Organism=Drosophila melanogaster, GI17864482, Length=888, Percent_Identity=25.7882882882883, Blast_Score=257, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24653289, Length=888, Percent_Identity=25.7882882882883, Blast_Score=257, Evalue=3e-68,
Organism=Drosophila melanogaster, GI21355675, Length=843, Percent_Identity=24.7924080664294, Blast_Score=256, Evalue=5e-68,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_ARCFU (O29622)

Other databases:

- EMBL:   AE000782
- PIR:   A69329
- RefSeq:   NP_069467.1
- ProteinModelPortal:   O29622
- SMR:   O29622
- GeneID:   1483851
- GenomeReviews:   AE000782_GR
- KEGG:   afu:AF0633
- NMPDR:   fig|224325.1.peg.626
- TIGR:   AF_0633
- HOGENOM:   HBG577712
- OMA:   NFIDECK
- ProtClustDB:   PRK06039
- BioCyc:   AFUL224325:AF_0633-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 118886; Mature: 118886

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 589-589

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPAKYSPKDVESEIFKFWEDNDIYRKVKEKGGRKFYFVDGPPYTTGRIHLGTAWNKVLK
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEECHHHHHHHH
DTILRYKRMMGFAPTDTPGWDMHGLPIEVKVEQELGFRTKRDIESFGIDKFIERCMNYAL
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
ANKDAMTEQFKSLAVWMDWENPYMTIKAEYMNAAWFAIKRAHERGLLERKKMVVNWCHRC
CCCHHHHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETALADAEVEYWDEEDPSIYVKFPVKGEKDTYIVIWTTTPWTLPANMAVAVHPSLEYAKF
HHHHHCCCCEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHH
RAVKDGKVEYLILAKELADSVLGKGDYDSWEVVETYLGEDLEGLEYEHPLADEVPLQKNW
EECCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
KHQVFFADFVTAENTGCVHIAPGHGVEDYELGVEKGLEVFNPVDDRGVYTEEAGKYAGKH
CCEEEEEEEEECCCCCEEEECCCCCCCHHHHCHHHCHHHHCCCCCCCCCHHHHHHHHHHH
VKEANDDIIDDLYRKDLLLAEERIVHRYGHCWRCKTPIIYRATEQWFIKISELKDEMLEE
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHH
IDKVMWIPEWAGSARFKDWVSNAKDWCISRQRYWGIPIPVWICEKCGEMKVVGSINEIEW
HHHHEECCCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHCCC
ENDLDLHRPKIDAVTFSCQCGGVMRRVPDVFDVWFDSGVASWGSIAYPLRKDKFEELWPA
CCCCCCCCCCCCEEEEEECCCHHHHHCHHHHHHHHHCCCCCCCCEECCHHHHHHHHHCCH
DFITEGHDQTRGWFYSQLGTSVVCFDKAPYKAVLMHGFTLDEQGRKMSKSLGNVVEPEEV
HHHCCCCCHHCCEEHHHHCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
VGQIGVDGFRLYVLYSAPWEDLRFSWEEARNINRMLNVVWNAVRFAHTYMSLDNYSFGEK
HHHCCCCEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GELKIEDRWILSRLESFIKEANEAMEGYQVHRVVRAFFDFFVEDFSRWYIQIIRPRVWEE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDSPSKLAAYYTMFRVIDRSLRAIAPFAPLIAEWFYQHVVKEFREGEESIFMEEYSTAEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHCCCCEE
EMIDGELEAAMKVAKEIVEAAANARNKAKRKLRWPLRELVIESGSEKVRKAVEMLEETIL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHH
SQCNVKQVRVVDSFEKEIEIKPNYKYIGPLLKEKAGEFAKYVASLKEIPEKLVFDGVELD
HHCCCHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKQAIVVDYRLPEGYEYAEFSGGVVYIYKELDDELVREAFAREVIRRIQEMRKELDLDVE
CCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EFIETTVEMDAELVKGWEDYIKSETRSQKLVFGKAEGYVREWNIEGKKVKIGIKRLRG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEEEEHHHCCC
>Mature Secondary Structure
MLPAKYSPKDVESEIFKFWEDNDIYRKVKEKGGRKFYFVDGPPYTTGRIHLGTAWNKVLK
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEECHHHHHHHH
DTILRYKRMMGFAPTDTPGWDMHGLPIEVKVEQELGFRTKRDIESFGIDKFIERCMNYAL
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
ANKDAMTEQFKSLAVWMDWENPYMTIKAEYMNAAWFAIKRAHERGLLERKKMVVNWCHRC
CCCHHHHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETALADAEVEYWDEEDPSIYVKFPVKGEKDTYIVIWTTTPWTLPANMAVAVHPSLEYAKF
HHHHHCCCCEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCCEEEECCCHHHHHH
RAVKDGKVEYLILAKELADSVLGKGDYDSWEVVETYLGEDLEGLEYEHPLADEVPLQKNW
EECCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
KHQVFFADFVTAENTGCVHIAPGHGVEDYELGVEKGLEVFNPVDDRGVYTEEAGKYAGKH
CCEEEEEEEEECCCCCEEEECCCCCCCHHHHCHHHCHHHHCCCCCCCCCHHHHHHHHHHH
VKEANDDIIDDLYRKDLLLAEERIVHRYGHCWRCKTPIIYRATEQWFIKISELKDEMLEE
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHH
IDKVMWIPEWAGSARFKDWVSNAKDWCISRQRYWGIPIPVWICEKCGEMKVVGSINEIEW
HHHHEECCCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHCCC
ENDLDLHRPKIDAVTFSCQCGGVMRRVPDVFDVWFDSGVASWGSIAYPLRKDKFEELWPA
CCCCCCCCCCCCEEEEEECCCHHHHHCHHHHHHHHHCCCCCCCCEECCHHHHHHHHHCCH
DFITEGHDQTRGWFYSQLGTSVVCFDKAPYKAVLMHGFTLDEQGRKMSKSLGNVVEPEEV
HHHCCCCCHHCCEEHHHHCCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
VGQIGVDGFRLYVLYSAPWEDLRFSWEEARNINRMLNVVWNAVRFAHTYMSLDNYSFGEK
HHHCCCCEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GELKIEDRWILSRLESFIKEANEAMEGYQVHRVVRAFFDFFVEDFSRWYIQIIRPRVWEE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RDSPSKLAAYYTMFRVIDRSLRAIAPFAPLIAEWFYQHVVKEFREGEESIFMEEYSTAEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHCCCCEE
EMIDGELEAAMKVAKEIVEAAANARNKAKRKLRWPLRELVIESGSEKVRKAVEMLEETIL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHH
SQCNVKQVRVVDSFEKEIEIKPNYKYIGPLLKEKAGEFAKYVASLKEIPEKLVFDGVELD
HHCCCHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKQAIVVDYRLPEGYEYAEFSGGVVYIYKELDDELVREAFAREVIRRIQEMRKELDLDVE
CCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EFIETTVEMDAELVKGWEDYIKSETRSQKLVFGKAEGYVREWNIEGKKVKIGIKRLRG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475