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The map label for this gene is pmm

Identifier: 11498070

GI number: 11498070

Start: 414321

End: 415661

Strand: Reverse

Name: pmm

Synonym: AF0458

Alternate gene names: 11498070

Gene position: 415661-414321 (Counterclockwise)

Preceding gene: 11498072

Following gene: 11498067

Centisome position: 19.08

GC content: 50.78

Gene sequence:

>1341_bases
ATGAGAGCAGGAGGAGCCGGAGAGCTTTTTGGAACCAATGGAGTTAGAGGGATTGCAAATTCCGAGCTTACAGCCGATAT
GGCTCTAAACCTTGGCAGGACCATTGGAACGCTAAGGCAGGGCAAGATAGCCATCGCATGCGACACGAGAATTTCAAGCT
CAATGCTCAAATCTGCAGTTTCGGCTGGAATAATGTCCACTGGCAGTGATGTTGTTGACATCGGCATTGCCCCCACACCG
GCCCTTCAGTATTACGTGAAGGAGACGGACTGCTCAGCAGGGGTTATAGTGACTGCAAGCCACAATCCGAGAGAGTATAA
CGGCATCAAGTTCGTTCAGGAGAATGGGGTGGAGTTCTACAGGGAGATGGACGAGGAGAGCGAGAGAGTTTACATGAGCA
AGAAGTTCAGGATCGCAGAATGGAGCGAGGTGGGGCAGCTTTACCAAGACAATTCGGGGCTGAGGAAGTACATAGAGGCC
ATCATCAACTCAGTTGAGCTTGACAAATCCTACAGGGTTGCCGTTGACTGTGGAAACGGAGCTGGCTGCTTCACCACTCC
CGAAATTCTGAAGGAGCTTGGCTGCGACGTTTATGGAATAAACTGCAACCCCGACGGCAGATTCCCCGCAAGAAATCCCG
AGCCTGTAGAGGCTTCGCTGGATTTGCTGAAGAAGGCTGTTGTTGACTTCAGGGCAGATTTCGGCGTTGCTCACGATGGA
GATGCTGATAGAGCGGTTTTTGTTGACGAGAAGGGAAACTTCGTCAATGAGGATGTGATGCTCGCTCTCATGGCAAAGCA
CTACGTTGAGAAGAATGGAGGGGGGTTGGTGGTAACTCCAGTCTCATCCTCAAAATGCGTTGAAGATGCGGTTAAGATGG
CTGGTGGAGAGATTATTTACACCGCCGTAGGCTCGCCAGTGGTTGCAAAGGTGATGATTGAAAAGGAAGCTGTTTTCGGC
GGAGAGGGAAATGGTGGGCTGATTTTCCCAGAGCATCTCATTGCGAGAGATGGGGGGATGAGCGTTGCAAAGGTTCTGGA
GCTTCTTGATGAGAAAAGAAAGAGGTTGAGCGAGCTTGCGGCTGAGATTCCAAGATACCACATTGTAAAAGGCAAAGTGG
AGTGCAGGGAGAAGAAGAGACTGCTTGAAGGGCTGAAGGAGGAGTTTCCCGAAGCCAATCACATCGATGGAGCGAGGATT
GACTTCGAGGACGGGTGGGTTTTAATTCGCCCCTCAGGGACTGAGCCCATTGCAAGGGTTTATGCGGAAGCAAAAACTGA
GGATAGGGCGAGGGAGCTTTACGAGCTGGGATTGAGGGCGATAAAAAAGATTTTAGGCTAA

Upstream 100 bases:

>100_bases
ATTAGAAGGATCGTAAGGAGCGGGCGTTCGACAGGGAGCATCAAAAGTGATTCGGAATCTCGGTAAAAAACTTTTTGAAC
ATTCATTCTGAATTGCTGCC

Downstream 100 bases:

>100_bases
GAGGCTCTGGAACTTTCTTGCCATCCTTATGCCCTTTATTTTTAGCTTTCCGGTGGCTAAAAGCTTTAGAGTTTTCAGCA
TTCCCGCCTTTCCCGTTGCG

Product: phosphomannomutase (pmm)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MRAGGAGELFGTNGVRGIANSELTADMALNLGRTIGTLRQGKIAIACDTRISSSMLKSAVSAGIMSTGSDVVDIGIAPTP
ALQYYVKETDCSAGVIVTASHNPREYNGIKFVQENGVEFYREMDEESERVYMSKKFRIAEWSEVGQLYQDNSGLRKYIEA
IINSVELDKSYRVAVDCGNGAGCFTTPEILKELGCDVYGINCNPDGRFPARNPEPVEASLDLLKKAVVDFRADFGVAHDG
DADRAVFVDEKGNFVNEDVMLALMAKHYVEKNGGGLVVTPVSSSKCVEDAVKMAGGEIIYTAVGSPVVAKVMIEKEAVFG
GEGNGGLIFPEHLIARDGGMSVAKVLELLDEKRKRLSELAAEIPRYHIVKGKVECREKKRLLEGLKEEFPEANHIDGARI
DFEDGWVLIRPSGTEPIARVYAEAKTEDRARELYELGLRAIKKILG

Sequences:

>Translated_446_residues
MRAGGAGELFGTNGVRGIANSELTADMALNLGRTIGTLRQGKIAIACDTRISSSMLKSAVSAGIMSTGSDVVDIGIAPTP
ALQYYVKETDCSAGVIVTASHNPREYNGIKFVQENGVEFYREMDEESERVYMSKKFRIAEWSEVGQLYQDNSGLRKYIEA
IINSVELDKSYRVAVDCGNGAGCFTTPEILKELGCDVYGINCNPDGRFPARNPEPVEASLDLLKKAVVDFRADFGVAHDG
DADRAVFVDEKGNFVNEDVMLALMAKHYVEKNGGGLVVTPVSSSKCVEDAVKMAGGEIIYTAVGSPVVAKVMIEKEAVFG
GEGNGGLIFPEHLIARDGGMSVAKVLELLDEKRKRLSELAAEIPRYHIVKGKVECREKKRLLEGLKEEFPEANHIDGARI
DFEDGWVLIRPSGTEPIARVYAEAKTEDRARELYELGLRAIKKILG
>Mature_446_residues
MRAGGAGELFGTNGVRGIANSELTADMALNLGRTIGTLRQGKIAIACDTRISSSMLKSAVSAGIMSTGSDVVDIGIAPTP
ALQYYVKETDCSAGVIVTASHNPREYNGIKFVQENGVEFYREMDEESERVYMSKKFRIAEWSEVGQLYQDNSGLRKYIEA
IINSVELDKSYRVAVDCGNGAGCFTTPEILKELGCDVYGINCNPDGRFPARNPEPVEASLDLLKKAVVDFRADFGVAHDG
DADRAVFVDEKGNFVNEDVMLALMAKHYVEKNGGGLVVTPVSSSKCVEDAVKMAGGEIIYTAVGSPVVAKVMIEKEAVFG
GEGNGGLIFPEHLIARDGGMSVAKVLELLDEKRKRLSELAAEIPRYHIVKGKVECREKKRLLEGLKEEFPEANHIDGARI
DFEDGWVLIRPSGTEPIARVYAEAKTEDRARELYELGLRAIKKILG

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=31.6143497757848, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788361, Length=449, Percent_Identity=28.5077951002227, Blast_Score=164, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 48540; Mature: 48540

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGGAGELFGTNGVRGIANSELTADMALNLGRTIGTLRQGKIAIACDTRISSSMLKSAV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
SAGIMSTGSDVVDIGIAPTPALQYYVKETDCSAGVIVTASHNPREYNGIKFVQENGVEFY
HHHHHCCCCCEEEECCCCCCHHEEEEEECCCCCCEEEEECCCCCCCCCEEEEHHCCHHHH
REMDEESERVYMSKKFRIAEWSEVGQLYQDNSGLRKYIEAIINSVELDKSYRVAVDCGNG
HHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
AGCFTTPEILKELGCDVYGINCNPDGRFPARNPEPVEASLDLLKKAVVDFRADFGVAHDG
CCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DADRAVFVDEKGNFVNEDVMLALMAKHYVEKNGGGLVVTPVSSSKCVEDAVKMAGGEIIY
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEE
TAVGSPVVAKVMIEKEAVFGGEGNGGLIFPEHLIARDGGMSVAKVLELLDEKRKRLSELA
EECCCCHHHHHHHHHHHEECCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AEIPRYHIVKGKVECREKKRLLEGLKEEFPEANHIDGARIDFEDGWVLIRPSGTEPIARV
HHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCCHHHHH
YAEAKTEDRARELYELGLRAIKKILG
HHHHCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRAGGAGELFGTNGVRGIANSELTADMALNLGRTIGTLRQGKIAIACDTRISSSMLKSAV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
SAGIMSTGSDVVDIGIAPTPALQYYVKETDCSAGVIVTASHNPREYNGIKFVQENGVEFY
HHHHHCCCCCEEEECCCCCCHHEEEEEECCCCCCEEEEECCCCCCCCCEEEEHHCCHHHH
REMDEESERVYMSKKFRIAEWSEVGQLYQDNSGLRKYIEAIINSVELDKSYRVAVDCGNG
HHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
AGCFTTPEILKELGCDVYGINCNPDGRFPARNPEPVEASLDLLKKAVVDFRADFGVAHDG
CCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DADRAVFVDEKGNFVNEDVMLALMAKHYVEKNGGGLVVTPVSSSKCVEDAVKMAGGEIIY
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCEEE
TAVGSPVVAKVMIEKEAVFGGEGNGGLIFPEHLIARDGGMSVAKVLELLDEKRKRLSELA
EECCCCHHHHHHHHHHHEECCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AEIPRYHIVKGKVECREKKRLLEGLKEEFPEANHIDGARIDFEDGWVLIRPSGTEPIARV
HHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCCHHHHH
YAEAKTEDRARELYELGLRAIKKILG
HHHHCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]