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Identifier: 11497970

GI number: 11497970

Start: 324520

End: 325878

Strand: Reverse

Name: Not Available

Synonym: AF0358

Alternate gene names: 11497970

Gene position: 325878-324520 (Counterclockwise)

Preceding gene: 11497973

Following gene: 11497969

Centisome position: 14.96

GC content: 49.45

Gene sequence:

>1359_bases
ATGCAAATGATTGCTGAAATATATTATGAACGGGGAACAATTGTTGTTAAAGGTGATGCTCACGTTCCTCATGCTAAGTT
CGATTCTCGAAGCGGAACTTACAGGGCGCTTGCCTTCAGATATAGGGACATAATCGAGTACTTTGAAAGTAACGGCATTG
AGTTTGTTGACAACGCAGCGGACCCAATTCCCACACCCTACTTCGATGCTGAAATCAGCCTGAGAGATTATCAGGAAAAG
GCGCTGGAGAGGTGGCTTGTTGATAAAAGAGGTTGTATTGTCCTTCCAACAGGCTCAGGAAAAACTCACGTTGCAATGGC
TGCTATTAACGAGCTTTCAACCCCAACTCTTATTGTGGTCCCAACTCTTGCCCTCGCTGAACAGTGGAAGGAGAGGCTGG
GAATTTTCGGTGAGGAGTACGTTGGAGAGTTCAGTGGCAGAATAAAAGAGCTGAAACCCCTCACCGTCTCAACCTACGAC
TCCGCATACGTAAACGCTGAAAAGCTGGGAAACAGGTTTATGCTTCTCATTTTCGATGAGGTGCACCACCTTCCAGCCGA
GTCCTACGTCCAGATAGCTCAGATGTCTATTGCTCCCTTCAGGCTGGGACTGACGGCAACTTTCGAAAGGGAGGATGGAA
GGCATGAAATTCTAAAGGAAGTGGTTGGTGGGAAGGTTTTCGAGCTTTTTCCAGACAGCCTGGCGGGAAAGCACCTTGCG
AAATACACGATAAAAAGAATTTTTGTCCCTCTTGCTGAGGACGAGAGGGTGGAGTACGAGAAAAGGGAGAAAGTGTACAA
GCAGTTTCTCAGGGCAAGGGGAATAACGCTGAGAAGGGCGGAGGACTTCAACAAGATAGTTATGGCCTCTGGATACGATG
AAAGGGCTTATGAGGCGTTGAGGGCGTGGGAAGAGGCGAGGAGGATAGCCTTTAACTCCAAAAACAAAATCAGGAAGCTG
AGGGAGATACTCGAGAGGCACAGGAAAGACAAAATCATAATCTTCACCCGCCACAACGAGCTCGTCTACAGGATTTCGAA
AGTTTTTCTGATTCCGGCAATAACGCATCGAACCAGCAGGGAGGAGAGGGAGGAGATACTTGAGGGCTTCAGGACGGGCA
GATTCAGGGCAATTGTGAGCAGCCAGGTTCTCGACGAGGGGATTGACGTGCCTGATGCCAACGTCGGTGTGATAATGAGC
GGTAGCGGTAGCGCGAGGGAGTACATCCAGCGACTCGGGAGAATTCTCAGACCGTCCAAGGGGAAAAAGGAAGCCGTGCT
GTATGAGCTGATTTCCAGAGGGACAGGAGAGGTGAACACAGCGAGGAGGAGAAAGAATGCTGCCAAAGGAGCTGCTTGA

Upstream 100 bases:

>100_bases
ATTTTTCCCGTTGTTGCGGCTGCTGAAGATGCAGAACGTTGTGAAGGAAGTAAAGTGTTATTCACCTGCCAGCAAAGCTT
AAAGGTATGAAAACGGAGGT

Downstream 100 bases:

>100_bases
CGTCAGAAGGGCAAAGGGAAGAATTTTTCCGAAATTTGCGGATGAGAGGGACTACGAACTGGCGGAAAAGGTAATTGAGA
TTTTCAAGAAGGGATTGGGA

Product: DNA repair protein RAD25

Products: NA

Alternate protein names: Type III Restriction Res Subunit; DNA Repair Helicase; Helicase Domain-Containing Protein; Helicase Domain Protein; ATP-Dependent DNA Helicase; DNA Repair Helicase RAD; Helicase; Type III Restriction Res Subunit Family; DNA Repair Protein Rad; DNA Repair Helicase Rad; DNA Helicase; DNA Repair Protein RAD; Superfamily II DNA/RNA Helicase; DNA/RNA Helicase; DNA Repair Protein; DNA/RNA Helicase Superfamily II; DNA-Repair Protein; Helicase-Like Protein; Helicase Protein; DEAD/DEAH Box Helicase Domain-Containing Protein; ATP-Dependent Helicase; DNA Or RNA Helicase Of Superfamily II; DNA/RNA Repair Helicase; DNA-Repair Helicase; Helicase ATP-Dependent; Helicase DNA Repair; DNA Or RNA Helicase; Helicase DNA Repair Rad; RAD25-Type DNA Repair Helicase; DNA Repair Related Protein; Restriction; RNA Polymerase Sigma; DEAD/DEAH Box Helicase-Like; Restriction Endonuclease Family Protein; DNA-Helicase; XPB/RAD25-Related Helicase; Helicase ATP-Dependent Intein-Containing; DNA Or RNA Helicase Of Superfamily Protein II; DEAD/DEAH Box Helicase

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MQMIAEIYYERGTIVVKGDAHVPHAKFDSRSGTYRALAFRYRDIIEYFESNGIEFVDNAADPIPTPYFDAEISLRDYQEK
ALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPTLIVVPTLALAEQWKERLGIFGEEYVGEFSGRIKELKPLTVSTYD
SAYVNAEKLGNRFMLLIFDEVHHLPAESYVQIAQMSIAPFRLGLTATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLA
KYTIKRIFVPLAEDERVEYEKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEALRAWEEARRIAFNSKNKIRKL
REILERHRKDKIIIFTRHNELVYRISKVFLIPAITHRTSREEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMS
GSGSAREYIQRLGRILRPSKGKKEAVLYELISRGTGEVNTARRRKNAAKGAA

Sequences:

>Translated_452_residues
MQMIAEIYYERGTIVVKGDAHVPHAKFDSRSGTYRALAFRYRDIIEYFESNGIEFVDNAADPIPTPYFDAEISLRDYQEK
ALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPTLIVVPTLALAEQWKERLGIFGEEYVGEFSGRIKELKPLTVSTYD
SAYVNAEKLGNRFMLLIFDEVHHLPAESYVQIAQMSIAPFRLGLTATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLA
KYTIKRIFVPLAEDERVEYEKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEALRAWEEARRIAFNSKNKIRKL
REILERHRKDKIIIFTRHNELVYRISKVFLIPAITHRTSREEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMS
GSGSAREYIQRLGRILRPSKGKKEAVLYELISRGTGEVNTARRRKNAAKGAA
>Mature_452_residues
MQMIAEIYYERGTIVVKGDAHVPHAKFDSRSGTYRALAFRYRDIIEYFESNGIEFVDNAADPIPTPYFDAEISLRDYQEK
ALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPTLIVVPTLALAEQWKERLGIFGEEYVGEFSGRIKELKPLTVSTYD
SAYVNAEKLGNRFMLLIFDEVHHLPAESYVQIAQMSIAPFRLGLTATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLA
KYTIKRIFVPLAEDERVEYEKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEALRAWEEARRIAFNSKNKIRKL
REILERHRKDKIIIFTRHNELVYRISKVFLIPAITHRTSREEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMS
GSGSAREYIQRLGRILRPSKGKKEAVLYELISRGTGEVNTARRRKNAAKGAA

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557563, Length=447, Percent_Identity=26.8456375838926, Blast_Score=123, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17556358, Length=447, Percent_Identity=27.0693512304251, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6322048, Length=407, Percent_Identity=27.7641277641278, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI221331068, Length=403, Percent_Identity=27.0471464019851, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24662247, Length=403, Percent_Identity=27.0471464019851, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51769; Mature: 51769

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMIAEIYYERGTIVVKGDAHVPHAKFDSRSGTYRALAFRYRDIIEYFESNGIEFVDNAA
CCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCC
DPIPTPYFDAEISLRDYQEKALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPTLIVV
CCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEHHHHHHHCCCCEEEEE
PTLALAEQWKERLGIFGEEYVGEFSGRIKELKPLTVSTYDSAYVNAEKLGNRFMLLIFDE
CCHHHHHHHHHHHCCCCHHHHHHHHCHHHHCCCCEEEECCCCEEEHHHHCCEEEEEEEHH
VHHLPAESYVQIAQMSIAPFRLGLTATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLA
HHHCCHHHHHHHHHHHCCCEEECEEEEEECCCCHHHHHHHHHCCEEEECCCHHHHHHHHH
KYTIKRIFVPLAEDERVEYEKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEAL
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHHHHH
RAWEEARRIAFNSKNKIRKLREILERHRKDKIIIFTRHNELVYRISKVFLIPAITHRTSR
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCH
EEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSK
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCC
GKKEAVLYELISRGTGEVNTARRRKNAAKGAA
CCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MQMIAEIYYERGTIVVKGDAHVPHAKFDSRSGTYRALAFRYRDIIEYFESNGIEFVDNAA
CCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCC
DPIPTPYFDAEISLRDYQEKALERWLVDKRGCIVLPTGSGKTHVAMAAINELSTPTLIVV
CCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEHHHHHHHCCCCEEEEE
PTLALAEQWKERLGIFGEEYVGEFSGRIKELKPLTVSTYDSAYVNAEKLGNRFMLLIFDE
CCHHHHHHHHHHHCCCCHHHHHHHHCHHHHCCCCEEEECCCCEEEHHHHCCEEEEEEEHH
VHHLPAESYVQIAQMSIAPFRLGLTATFEREDGRHEILKEVVGGKVFELFPDSLAGKHLA
HHHCCHHHHHHHHHHHCCCEEECEEEEEECCCCHHHHHHHHHCCEEEECCCHHHHHHHHH
KYTIKRIFVPLAEDERVEYEKREKVYKQFLRARGITLRRAEDFNKIVMASGYDERAYEAL
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHHHHH
RAWEEARRIAFNSKNKIRKLREILERHRKDKIIIFTRHNELVYRISKVFLIPAITHRTSR
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCH
EEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSK
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCC
GKKEAVLYELISRGTGEVNTARRRKNAAKGAA
CCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA