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The map label for this gene is wrbA

Identifier: 11497955

GI number: 11497955

Start: 314185

End: 314760

Strand: Reverse

Name: wrbA

Synonym: AF0343

Alternate gene names: 11497955

Gene position: 314760-314185 (Counterclockwise)

Preceding gene: 11497956

Following gene: 11497954

Centisome position: 14.45

GC content: 52.43

Gene sequence:

>576_bases
ATGGCCAGGATTCTTGTTATTTTTCATTCCATCACGGGCAACACGATGAAGCTCGCAAAGGCCGTTGCTGATGGTGCGAG
GGAAGGAGGAGCGGAGGTTGCTGTTAAGAGAGTTCCCGAAACCATCCCGGCTGAAATCCTCGAAAAGAACCCCGGCTACG
TTAAAGTAAGGGAAGAGCTTGAAAGCTTCGAGGTTGCAAGGCCAGAGGAGCTTCAAGATTATGATGCAATCATTTTTGGC
TCTCCGACGAGATTTGGAGTGATGTCCTCGCAGATGAAGCAGTTCATTGATATGACGGGAAGGTTGTGGATGGAGAGGAG
GCTTGAGGGCAAGGTTGGGGCTGTTTTCACCTCAAACGAGATGCCCCACGGCGGTAAGGAGGCGACGCTGCTCTCAATGC
TCCTTCCTCTCTTCGCACACGGGATGATTATTGTCGGACTGCCCCCGGCGAAAGAACTCTACAGGGCTGGAAGCTACTAC
GGGGCGGCATCAACAGGAGTTCCCAAGGAGGATGACTTGCAGGTTGCAAAAATGCTCGGAAAAAGGGTGGCAGAGGTGGC
TGAAAAGCTCTGCTAA

Upstream 100 bases:

>100_bases
GCCTTCAAAGCTGAGAAATCCGGGAAGCTTACGGCCTTCTCCTACTGCAACATCCATGGCCTCTGGATGGGAGAGGCGAC
GCTAAGCTTGGAGTGATTGA

Downstream 100 bases:

>100_bases
ACTTTACCGTTTGCAATTTTTACCTTTTCCTTAGCCTGAGGTCAGACAGGCAAATGGTTCGAATTTCGTAAATTTGGATT
TTTCAAAATCCAGAAAAATT

Product: tryptophan repressor binding protein (wrbA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MARILVIFHSITGNTMKLAKAVADGAREGGAEVAVKRVPETIPAEILEKNPGYVKVREELESFEVARPEELQDYDAIIFG
SPTRFGVMSSQMKQFIDMTGRLWMERRLEGKVGAVFTSNEMPHGGKEATLLSMLLPLFAHGMIIVGLPPAKELYRAGSYY
GAASTGVPKEDDLQVAKMLGKRVAEVAEKLC

Sequences:

>Translated_191_residues
MARILVIFHSITGNTMKLAKAVADGAREGGAEVAVKRVPETIPAEILEKNPGYVKVREELESFEVARPEELQDYDAIIFG
SPTRFGVMSSQMKQFIDMTGRLWMERRLEGKVGAVFTSNEMPHGGKEATLLSMLLPLFAHGMIIVGLPPAKELYRAGSYY
GAASTGVPKEDDLQVAKMLGKRVAEVAEKLC
>Mature_190_residues
ARILVIFHSITGNTMKLAKAVADGAREGGAEVAVKRVPETIPAEILEKNPGYVKVREELESFEVARPEELQDYDAIIFGS
PTRFGVMSSQMKQFIDMTGRLWMERRLEGKVGAVFTSNEMPHGGKEATLLSMLLPLFAHGMIIVGLPPAKELYRAGSYYG
AASTGVPKEDDLQVAKMLGKRVAEVAEKLC

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=203, Percent_Identity=43.8423645320197, Blast_Score=149, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6319849, Length=204, Percent_Identity=33.8235294117647, Blast_Score=104, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320235, Length=204, Percent_Identity=30.8823529411765, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 20914; Mature: 20782

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARILVIFHSITGNTMKLAKAVADGAREGGAEVAVKRVPETIPAEILEKNPGYVKVREEL
CCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCEEEHHHHH
ESFEVARPEELQDYDAIIFGSPTRFGVMSSQMKQFIDMTGRLWMERRLEGKVGAVFTSNE
HHHCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
MPHGGKEATLLSMLLPLFAHGMIIVGLPPAKELYRAGSYYGAASTGVPKEDDLQVAKMLG
CCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
KRVAEVAEKLC
HHHHHHHHHCC
>Mature Secondary Structure 
ARILVIFHSITGNTMKLAKAVADGAREGGAEVAVKRVPETIPAEILEKNPGYVKVREEL
CEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHCCCCEEEHHHHH
ESFEVARPEELQDYDAIIFGSPTRFGVMSSQMKQFIDMTGRLWMERRLEGKVGAVFTSNE
HHHCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
MPHGGKEATLLSMLLPLFAHGMIIVGLPPAKELYRAGSYYGAASTGVPKEDDLQVAKMLG
CCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
KRVAEVAEKLC
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA