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The map label for this gene is yncB [H]

Identifier: 114800551

GI number: 114800551

Start: 2597382

End: 2598428

Strand: Reverse

Name: yncB [H]

Synonym: HNE_2470

Alternate gene names: 114800551

Gene position: 2598428-2597382 (Counterclockwise)

Preceding gene: 114797189

Following gene: 114799727

Centisome position: 70.13

GC content: 53.01

Gene sequence:

>1047_bases
ATGCCGGTTAGAATAAACCCACACTGGATTCTGGCGCGTACGCCAATTAAAGGGTGGCCCGTTGATGAGGATTTTTCTTG
GCGCGAAGCCCCGGCGATCTTGCCTCAGCTGGGACAAATGTTGACGCGCACGATCTACCTTTCGCTTGATCCTTATCAAT
GGGGGCGCCGGCGCAGAGGTGTCGAAATTCCTGGCGAAGTTTGCCATGGCCGTACCGTTTCGCAGGTTTTGCAAAGTCGT
ATAAAAGGATTTGAGGCAGGCGATTATGTGTTCAACACAAATGGCTGGCAGACTTACGGCCTTACAGGTGAAGGCATATC
TGATTTCGGCTATATGCTACCGCGCAAGATTGATCCGAACATGGCGCCAATTTCTTCCGCCCTCGGCATTCTCGGAATGC
TGGGGTTAACGGCCTATGCTGGCATTGTCGTGCAATGTGCGCCGCAACCGGGAGAAACGGTTGTAATCTCCGCCGCGTCG
GGCGGCGTAGGGCAAGTTGCTGGTCAGTTGGCAAAATTGCGAGGGTGCCGGGTCGTGGGAATCGCGGGCCGTGAAGAAAA
GTGCGCCTATGTGCGAGATACTCTGGGGCTGGACGCCTGCATTTCGCATCTCGATTCGGACTTTTCAGAGCGTTTGCGTG
CGGCCTGCCCGGACGGCGTTGATGTTTATTTCGAGAATGTAGGCGGGCGTGTGTTTGAGGCTGTTTTGAACCTTTTCAAT
ATAAATGCTCGCATCACCCTGTGTGGCCTTGCCTCGCAGTATGGCGCAATGAATGAAGACATCATGCAGGTATGGAATGA
GACTGGTGCAGATATATTCAGTAGACGAAACGTCATAGTGCATCCGCTTTTTGTAGGAAACTTTGTGGTGAGTCATCAAG
ATCAGTTTCTTGCCGAGATGGCTGAATGGTTGCGAGGCGGGCATATGCACTATCTGGAAGACATTTCCGATGGCCTTGAG
AGCGCACCGCAGGCATTTCGGGAGATGCTGGCAGGTGGAACTTTTGGAAAGACGCTCGTGCAGGTTTCAGCCGATCCCAC
GCTATAA

Upstream 100 bases:

>100_bases
TTTCATACTAACAATTTTCCACCCCTGGCGTCATTGATTGACATGGGGTGAGCCCGCCGCTCTGTTTGGTTTCGGGGCTC
AGTGCAGCATTGGAGTGTTT

Downstream 100 bases:

>100_bases
GGCGGATCATAAAGTGGCGTGATCCTCGCCAAAGATTCCAGAATAATCGGAATACGGAATTGTAAGGTGCATGCCCATTT
GCAAATATCGGCATGTTCAA

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPVRINPHWILARTPIKGWPVDEDFSWREAPAILPQLGQMLTRTIYLSLDPYQWGRRRRGVEIPGEVCHGRTVSQVLQSR
IKGFEAGDYVFNTNGWQTYGLTGEGISDFGYMLPRKIDPNMAPISSALGILGMLGLTAYAGIVVQCAPQPGETVVISAAS
GGVGQVAGQLAKLRGCRVVGIAGREEKCAYVRDTLGLDACISHLDSDFSERLRAACPDGVDVYFENVGGRVFEAVLNLFN
INARITLCGLASQYGAMNEDIMQVWNETGADIFSRRNVIVHPLFVGNFVVSHQDQFLAEMAEWLRGGHMHYLEDISDGLE
SAPQAFREMLAGGTFGKTLVQVSADPTL

Sequences:

>Translated_348_residues
MPVRINPHWILARTPIKGWPVDEDFSWREAPAILPQLGQMLTRTIYLSLDPYQWGRRRRGVEIPGEVCHGRTVSQVLQSR
IKGFEAGDYVFNTNGWQTYGLTGEGISDFGYMLPRKIDPNMAPISSALGILGMLGLTAYAGIVVQCAPQPGETVVISAAS
GGVGQVAGQLAKLRGCRVVGIAGREEKCAYVRDTLGLDACISHLDSDFSERLRAACPDGVDVYFENVGGRVFEAVLNLFN
INARITLCGLASQYGAMNEDIMQVWNETGADIFSRRNVIVHPLFVGNFVVSHQDQFLAEMAEWLRGGHMHYLEDISDGLE
SAPQAFREMLAGGTFGKTLVQVSADPTL
>Mature_347_residues
PVRINPHWILARTPIKGWPVDEDFSWREAPAILPQLGQMLTRTIYLSLDPYQWGRRRRGVEIPGEVCHGRTVSQVLQSRI
KGFEAGDYVFNTNGWQTYGLTGEGISDFGYMLPRKIDPNMAPISSALGILGMLGLTAYAGIVVQCAPQPGETVVISAASG
GVGQVAGQLAKLRGCRVVGIAGREEKCAYVRDTLGLDACISHLDSDFSERLRAACPDGVDVYFENVGGRVFEAVLNLFNI
NARITLCGLASQYGAMNEDIMQVWNETGADIFSRRNVIVHPLFVGNFVVSHQDQFLAEMAEWLRGGHMHYLEDISDGLES
APQAFREMLAGGTFGKTLVQVSADPTL

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=343, Percent_Identity=35.2769679300292, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI226059133, Length=343, Percent_Identity=35.2769679300292, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI226246682, Length=359, Percent_Identity=33.983286908078, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI226246680, Length=359, Percent_Identity=33.983286908078, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI22748929, Length=359, Percent_Identity=33.983286908078, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI226056130, Length=251, Percent_Identity=38.2470119521912, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI28557745, Length=330, Percent_Identity=24.8484848484848, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI226510941, Length=351, Percent_Identity=41.025641025641, Blast_Score=251, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI133901712, Length=322, Percent_Identity=30.7453416149068, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI133901710, Length=322, Percent_Identity=30.7453416149068, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323504, Length=373, Percent_Identity=27.6139410187668, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38094; Mature: 37963

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRINPHWILARTPIKGWPVDEDFSWREAPAILPQLGQMLTRTIYLSLDPYQWGRRRRG
CCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHCCC
VEIPGEVCHGRTVSQVLQSRIKGFEAGDYVFNTNGWQTYGLTGEGISDFGYMLPRKIDPN
CCCCHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCCCHHHHHHHCCCCCCCC
MAPISSALGILGMLGLTAYAGIVVQCAPQPGETVVISAASGGVGQVAGQLAKLRGCRVVG
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEE
IAGREEKCAYVRDTLGLDACISHLDSDFSERLRAACPDGVDVYFENVGGRVFEAVLNLFN
ECCCCCHHHHHHHHCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHC
INARITLCGLASQYGAMNEDIMQVWNETGADIFSRRNVIVHPLFVGNFVVSHQDQFLAEM
CCCEEEEEECHHHHCCCCHHHHHHHHHCCHHHHHCCCEEEEEEECCCCHHHHHHHHHHHH
AEWLRGGHMHYLEDISDGLESAPQAFREMLAGGTFGKTLVQVSADPTL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
PVRINPHWILARTPIKGWPVDEDFSWREAPAILPQLGQMLTRTIYLSLDPYQWGRRRRG
CEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHCCC
VEIPGEVCHGRTVSQVLQSRIKGFEAGDYVFNTNGWQTYGLTGEGISDFGYMLPRKIDPN
CCCCHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCCCHHHHHHHCCCCCCCC
MAPISSALGILGMLGLTAYAGIVVQCAPQPGETVVISAASGGVGQVAGQLAKLRGCRVVG
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEE
IAGREEKCAYVRDTLGLDACISHLDSDFSERLRAACPDGVDVYFENVGGRVFEAVLNLFN
ECCCCCHHHHHHHHCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHC
INARITLCGLASQYGAMNEDIMQVWNETGADIFSRRNVIVHPLFVGNFVVSHQDQFLAEM
CCCEEEEEECHHHHCCCCHHHHHHHHHCCHHHHHCCCEEEEEEECCCCHHHHHHHHHHHH
AEWLRGGHMHYLEDISDGLESAPQAFREMLAGGTFGKTLVQVSADPTL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]